Ana nuna Metformin 500 don sarrafa ciwon sukari. Wannan cutar ta bambanta da sauran cututtuka ta hanyar yaduwar hanzari da haɗarin mutuwa. Kula da ciwon sukari shine ɗayan ayyukan fifiko da aka saita wa likitoci a duniya.
Sunan kasa da kasa mai zaman kansa
Sunan asalin duniya shine Metformin.
ATX
A10BA02.
Saki siffofin da abun da ke ciki
An samar dasu ta hanyar Allunan. Abun da ke ciki ya ƙunshi magungunan metformin hydrochloride da abubuwan taimako: silicon dioxide, magnesium stearic salt, copovidone, cellulose, Opadry II. Ba a samar da magunguna a saukad.
An samar dasu a cikin nau'ikan allunan, abun da ke ciki ya ƙunshi magungunan metformin hydrochloride da abubuwan taimako.
Aikin magunguna
Metformin (dimethylbiguanide) yana da tasirin maganin cutar suga. Tasirin kwayar halitta yana da alaƙa da ikon hana ayyukan gluconeogenesis a cikin jiki. A wannan yanayin, yawan ATP a cikin sel yana raguwa, wanda ke ƙarfafa rushewar sugars. Magungunan yana kara adadin glucose wanda ke shiga daga sararin samaniya a cikin tantanin halitta. Akwai haɓaka yawan adadin lactate da pyruvate a cikin kyallen.
Maganin yana rage yawan lalacewar mai, yana hana samuwar kitse mara iyaka.
Yayin amfani da biguanides, ana ganin canji a cikin aikin insulin, wanda ke haifar da raguwa a hankali a yawan adadin glucose a cikin jini. Ba ya motsa samuwar insulin ta hanyar ƙwayoyin beta, wanda ke ba da gudummawa ga ingantaccen taimako na hyperinsulinemia (ƙara yawan insulin a cikin jini).
A cikin marasa lafiya masu lafiya, shan Metformin baya haifar da raguwar sukari na jini. A wannan yanayin, ana ɗaukar shi don magance kiba saboda hana ci, rage yawan shan glucose daga ƙwayar gastrointestinal zuwa cikin jini.
Hakanan yana da kayan haɗin jini, shine, yana rage yawan adadin lipoproteins da yawa mai yawa wanda ke da alhakin ƙirƙirar filayen atherosclerotic. Yana da tasiri mai amfani akan aikin tasoshin jini da zuciya, yana hana bayyanar angiopathy (lalacewar jijiyoyi da jijiya a cikin ciwon suga).
Pharmacokinetics
Bayan gudanarwa na ciki na kwamfutar hannu, mafi girman taro dimethylbiguanide ya kai bayan awa 2.5. 6 sa'o'i bayan amfani na ciki, tsarin sha daga ƙwayar hanji ya gushe, daga baya kuma aka sami raguwar sannu a hankali a cikin adadin Metformin a cikin jini.
Kudin shiga cikin allurai na warkewa yana taimakawa wajen kula da yawan maganin a cikin plasma a cikin 1-2 μg a cikin lita 1.
Yin amfani da miyagun ƙwayoyi tare da abinci yana rage ɗaukar abu mai aiki daga plasma. Cum ɗin magani yana faruwa a cikin hanji, ciki, gyada mai narkewa. A bioavailability na miyagun ƙwayoyi ya kai 60%. Plasma sunadarai basu daure sosai.
An cire shi tare da kodan da 30% ba canzawa. Ragowar adadin mahaɗin yana cire hanta.
Kudin shiga cikin allurai na warkewa yana taimakawa wajen kula da yawan maganin a cikin plasma a cikin 1-2 μg a cikin lita 1.
Alamu don amfani
An tsara maganin don nau'in 1 ko nau'in ciwon sukari na 2. Yana da ƙari ga babban maganin cutar sankara (ta amfani da insulin ko rage ƙwayoyin glucose). Idan ciwon sukari mai dogaro da insulin, ana yin shi ne kawai a hade tare da insulin. A cikin nau'in ciwon sukari na 2, ana iya tsara maganin monotherapy.
Hakanan ana ba da shawarar don magance kiba, musamman idan wannan ilimin yana buƙatar kulawa da hankali koyaushe na glucose jini.
Contraindications
An sanya hannu cikin wadannan lamura:
- shekaru haƙuri har zuwa shekaru 15;
- hypersensitivity zuwa metformin da duk wani abin da ke jikin allunan;
- precoma;
- tabarbarewa na koda da gazawa (ƙaddarawar ƙirar creatinine);
- ketoacidosis;
- nama necrosis;
- rashin ruwa a jiki wanda yake haifar da amai ko gudawa;
- cutar lalacewar ƙafa;
- matsanancin cututtuka;
- girgiza jihar na haƙuri;
- m bugun zuciya;
- kasawar rashin haihuwa;
- abinci tare da adadin kuzari a kasa 1000 kcal;
- gazawar hanta;
- lactic acidosis (ciki har da cikin anamnesis);
- jaraba ga barasa;
- m da cuta mai saurin kamuwa da cuta wanda ke haifar da matsananciyar yunwar oxygen a cikin mutane;
- zazzabi
- manyan raunin da ya faru, ayyukan tiyata, da bayan aikin likita;
- amfani a kowane nau'i na abubuwa masu kunar bakin wake dauke da sinadarin aidin;
- m maye tare da ethanol;
- ciki
- lactation.
Ba a yarda da marasa lafiya na masu shan barasa su ɗauki Metformin 500 ba.
Tare da kulawa
Yakamata a yi taka tsantsan yayin ɗaukar abubuwa masu rage sukari saboda yiwuwar haɗarin maganganun cututtukan jini. Marasa lafiya suna buƙatar bin ka'idodin tsarin abinci mai gina jiki, bi daidai da wadataccen abinci na carbohydrates a ko'ina cikin rana. Tare da ƙara yawan nauyin jiki, karamin abu ya kamata a yi amfani dashi.
Yadda ake ɗaukar Metformin 500
Allunan ana ɗaukarsu a baka, ba tare da taunawa ba, tare da ruwa mai yawa. Idan mai haƙuri yana da wahala hadiye, to, an ba shi damar raba kwamfutar hannu zuwa sassa 2. Haka kuma, kashi na biyu na kwaya ya kamata ya bugu nan da nan bayan na farko.
Kafin ko bayan abinci
Karɓar baƙi ne kawai za'ayi bayan ci abinci.
Shan maganin don ciwon sukari
A cikin ciwon sukari, an tsara sashi na farko a cikin allunan 2 na 500 MG. Ba za a iya raba shi zuwa allurai 2 ko 3 ba: wannan yana taimaka wajan rage ƙarfin tasirin sakamako. Bayan makonni 2, adadin yana ƙaruwa zuwa matakin tabbatarwa - Allunan 3-4 na 0.5 g kowane .. Matsakaicin adadin yau da kullun na metformin shine 3 g.
Ana amfani da Metformin 500 ne kawai bayan abinci.
Game da amfani da Metformin tare da insulin, sashinta ba ya canzawa. Bayan haka, wani raguwa a cikin adadin insulin da aka ɗauka ana aiwatar dashi. Idan mai haƙuri ya cinye fiye da raka'a 40. insulin, sannan ragewa a cikin adonsa ya halatta kawai a tsarin asibiti.
Yadda ake ɗaukar nauyi
Don asarar nauyi, ana wajabta maganin 0.5 g sau 2 a rana, tabbatar bayan cin abinci. Idan tasirin asarar nauyi bai isa ba, to an tsara wani kashi na 0.5 g .. Tsawon lokacin jiyya don asarar nauyi kada ya zama fiye da makonni 3. Na gaba hanya ya kamata a maimaita kawai bayan wata daya.
A cikin aiwatar da asarar nauyi kuna buƙatar kunna wasanni.
Lokacin shakatawa
Rabin rayuwar dimethylbiguanide shine awoyi 6.5.
Sakamakon sakamako na Metformin 500
Haɓaka sakamako masu illa suna faruwa a kullun.
Gastrointestinal fili
Abubuwanda suka fi yawan faruwa sune: tashin zuciya, amai, gudawa, raguwar abinci, jin zafi a ciki da hanji. Sau da yawa marasa lafiya na iya jin takamaiman ɗanɗano na karfe a cikin rami na baka.
Yawancin sakamako masu illa na yau da kullun sune jin zafi a ciki da hanji.
Wadannan alamun suna bayyana ne kawai a farkon amfani da miyagun ƙwayoyi kuma daga baya wucewa. Ba a buƙatar magani na musamman don sauƙaƙe waɗannan bayyanar cututtuka ba.
Daga gefen metabolism
Yana da matukar wuya ga mai haƙuri ya inganta lactic acidosis. Wannan yanayin yana buƙatar sakewa.
A ɓangaren fata
Idan yanayin rashin hankalin a cikin marasa lafiya, halayen fata a cikin nau'in jan farfajiyar da itching na iya faruwa.
Tsarin Endocrin
Da wuya, ana iya lura da marasa lafiya da ke dauke da cututtukan thyroid ko adrenal gland functioning.
Cutar Al'aura
Allergic halayen faruwa ne kawai tare da ƙara mutum ji ga mahaifa. Mutum na iya haɓakawa: erythema, itching, redness na fata ta nau'in cutar urtikaria.
Idan yanayin rashin hankalin a cikin marasa lafiya, halayen fata a cikin nau'in jan farfajiyar da itching na iya faruwa.
Tasiri kan ikon sarrafa abubuwan inji
Babu wani tasiri mara kyau a cikin ikon fitar da abubuwa masu rikitarwa da fitar da abin hawa. Yakamata a yi taka tsantsan yayin yin kwatankwacin Metformin tare da sauran magunguna masu rage sukari, saboda zasu iya rage matakan sukari da gaske. Ba da shawarar tuki a cikin wannan yanayin don guje wa haɗarin haɗari.
Umarni na musamman
Amfani da maganin yana hade da wasu fasali. Yakamata a yi taka tsantsan wurin ci gaban faduwar zuciya, tabarbarewa koda, da hanta. Yayin aikin jiyya, ana buƙatar saka idanu akan glucometer.
An soke maganin ne kwanaki 2 kafin kuma a cikin kwanaki 2 bayan kamuwa da cututtukan fata da ke amfani da wakilai na kayan aikin rediyo. Hakanan dole ne a yi yayin da aka wajabta mai haƙuri hanyoyin yin aikin gaba ɗaya a cikin maganin cutar maganin janar ko na gida.
Tare da haɓaka kamuwa da cuta na urinary da gabobin ciki, kuna buƙatar gaggawa tuntuɓi likita.
Yi amfani da lokacin daukar ciki da lactation
An hana shi shan yayin ɗaukar yaro da shayarwa.
Gudanar da Metformin ga yara 500
Ga yara 'yan kasa da shekaru 15, ba a sanya maganin ba.
Yi amfani da tsufa
A cikin tsofaffi, daidaita sashi ya zama dole. Ba'a ba da shawarar irin waɗannan masu haƙuri ba da allurai na maganin. Ya kamata a yi amfani da kayan taimako na warkewa don rage tasirin sakamako. Wani lokacin ana tsara Metformin 400.
Aikace-aikacen aiki mara kyau
Game da rauni na koda, ya kamata a yi amfani da magani tare da taka tsantsan. Idan cutar sankara ce ta ci gaba, to sai a soke maganin, saboda amfani da shi na iya tayar da jijiyar wuya ga kodan. Daya daga cikin manufofin kula da ciwon sukari shine hana haɓakar ciwan koda da kuma lalacewar ƙasa.
Game da rauni na koda, ya kamata a yi amfani da miyagun ƙwayoyi tare da taka tsantsan, idan cutar sankara ce ta haɓaka, to an soke maganin.
Amfani don aikin hanta mai rauni
Tare da rikicewar hanta, ƙwayoyi sun bugu da hankali. Bambanta da tsananin lalacewar nama hanta na taimaka wa canji a cikin abinci. Ya kamata a sa ido sosai a kan abubuwan nuna alamun ingancin kere-kere da sauran sigogin nazarin halittu.
Yawan adadin 500 na Metformin
Yawan shaye-shaye na iya haifar da lactic acidosis, amma ba ya haɓaka hypoglycemia. Bayyanar cututtuka na lactic acidosis:
- amai
- zawo
- rashin jin daɗi a cikin ciki;
- hauhawar zafin jiki;
- ciwon tsoka
- zafi a ciki.
Idan babu kulawar likitanci a wannan lokacin tsananin wahala, tsananin wahala. Nan gaba, rashin daidaituwa ya faru.
Yi amfani da ceases tare da haɓakar acidosis. An kwantar da mara lafiyar cikin gaggawa. Hanya mafi inganci don magance jikin mutum shine hemodialysis.
Idan babu kulawar likita yayin yawan yawan damuwa, tsananin farin ciki, haushi.
Yin hulɗa tare da wasu kwayoyi
Ya kamata a kula da hankali kan yanayin gudanar da aikin sulfonyl-urea da insulin. Akwai haɗarin hauhawar haɓakar glucose na jini a cikin haƙuri. Tasirin hypoglycemic na biguanides an rage shi da magunguna masu zuwa:
- wakilan glucocorticosteroid na tsari da aikin gida;
- abubuwan abubuwa masu juyayi;
- glucagon;
- shirye-shiryen adrenaline;
- progestogens da estrogens;
- shirye-shirye na abubuwa da ke ɓoye ta glandar thyroid;
- abubuwan nicotinic acid;
- thiazide diuretics;
- maganin halittu;
- Cimetidine.
Inganta tasirin hypoglycemic:
- ACE masu hanawa;
- beta-2 adrenergic antagonists;
- MAO masu hanawa;
- Cyclophosphamide da misalanta;
- duk PVP marasa steroidal;
- Maganin Kawaus.
Ya kamata a kula da hankali kan yanayin gudanar da aikin sulfonyl-urea da insulin.
Shan wakilai masu dauke da sinadarin iodine don karatun X-ray suna canza yanayin metabolform, wanda shine dalilin da ya sa ya fara nuna sakamako. Zai iya haifar da mummunan rauni na koda.
Chlorpromazine yana hana fitowar insulin. Wannan na iya buƙatar haɓaka metformin.
Yawan cin abinci na biguanides yana ƙaruwa da hankali na Amilorid, Quinine, Vancomycin, Quinidine, Cimetidine, Triamteren, Ranitidine, Procainamide, Nifedipine.
Amfani da barasa
Barasa yana ƙara haɗarin lactic acidosis. A lokacin jiyya, ya kamata ka guji yin amfani da giya da duk magunguna da samfura na ethanol, saboda ba su da jituwa tare da Metformin.
Analogs
Analogs sune:
- Formmetin;
- Glucophage;
- Siofor;
- Metformin Siofor;
- Metformin Tsayi;
- Canform Metformin;
- Metformin Zentiva;
- Bagomet;
- Metfogamma;
- Langerine;
- Glycomet.
Formmetin na iya aiki azaman analogues na ƙwayar Metformin 500.
Magunguna kan bar sharuɗan
Ana buƙatar takardar sayan likita. Ya kamata a rubuta sunan samfurin a Latin.
Zan iya siye ba tare da takardar sayan magani ba
Haramun ne sayar da magani a cikin kantin magani ba tare da takardar sayan magani ba.
Magungunan kai na kanka na iya cutar da mutum sosai kuma yana haifar da matsanancin rashin ƙarfi.
Farashi don Metformin 500
Kudin magungunan a Rasha kusan 155 rubles ne. kowace fakitin 60 Allunan.
Yanayin ajiya na miyagun ƙwayoyi
Dole ne a adana shi a zazzabi a daki a busasshiyar wuri.
Ranar karewa
Magungunan ya dace don amfani na shekaru 3.
Mai masana'anta
An samar da maganin a masana'antar kamfanonin Indoco magunguna ltd, L-14, yankin masana'antu na Verna, Verna, Salcete, Goa - 403 722, India, Teva Pharmaceutical Enterprises Ltd. A Rasha, mutum na iya samun masana'antar magani a masana'antar Gedeon Richter.
Nazarin game da Metformin 500
A yanar gizo zaka iya karanta bita na kwararru da kuma marasa lafiyar da suka sha maganin.
Likitoci
Irina, mai shekara 50, endocrinologist, Moscow: “Metformin da analogues - Glucofage da Siofor - suna taimakawa sosai don magance cutar da rage matakan sukari. Masu maganin suna yarda da shi sosai, kawai a lokuta da wuya bayyanar cututtukan gastrointestinal ya faru a cikin kwanakin farko na maganin. Dogara da aka tsara yadda ya kamata yana rage buƙatar jikin mutum ga masu ciwon sukari. ”
Svetlana, mai shekara 52, endocrinologist, Smolensk: "Aikin ingantacciyar hanyar magance cutar sukari shine kula da matakan sukari a cikin iyakoki na al'ada da hana haɓaka haɗarin haɗari. Metformin yana bi da kyau tare da waɗannan ayyuka. A cikin marasa lafiya suna shan magani, ƙirar glycemic shine mafi kusanci ga al'ada."
Marasa lafiya
Anatoly, shekaru 50, St. Petersburg: "Metformin ya taimaka wajen hana faruwar harin hyperglycemia. Yanzu haka sukari bai wuce fiye da 8 mmol / L. Ina jin daɗi ba. Na ɗauki Metformin 1000 bisa ga umarnin."
Irina, mai shekara 48, Penza: “Shan maganin, ya rage yawan amfani da insulin.Zai yiwu a ci gaba da nuna alamun glycemia a cikin iyakokin da likita ya ba da shawarar. Bayan wadannan magungunan, ciwon tsoka ya tafi, kuma hangen nesa ya inganta. "
Rage nauyi
Olga, mai shekara 28, Ryazan: "Tare da taimakon Metformin 850, ya yiwu a rage nauyi da nauyin kilogram 8 a hade tare da ƙarancin kalori da ƙarancin carb. Na ji mai kyau, bana jin ƙushi ko ƙuna. Bayan magani na yi ƙoƙarin bin abincin daga kiba."
