An tsara allunan Glibomet musamman don marasa lafiya da ke fama da ciwon sukari mellitus-insulin-insulin (nau'in II) Haɗin maganin yana ba ku damar samun ingantaccen tasiri a cikin maganin wannan magani.
Sunan kasa da kasa mai zaman kansa
Metformin + glibenclamide (metformin + glibenclamide).
ATX
A10BD02.
Ana samun Glibomet a cikin nau'ikan allunan a cikin kwasfa.
Saki siffofin da abun da ke ciki
Kwayoyin a cikin kwasfa. Abubuwa masu aiki a cikin kwamfutar hannu 1: 2.5 glibenclamide, 400 mg metformin hydrochloride. Sauran abubuwan da aka gyara:
- microcrystalline cellulose;
- sitaci masara;
- magnesium stearate;
- talc;
- diethyl phthalate;
- cellulose acetate;
- colloidal silicon dioxide.
Aikin magunguna
Magungunan yana tattare da yawancin magungunan cututtukan cututtukan cututtukan fata. Yana da sakamako mai cutarwa da kuma cututtukan cututtukan zuciya.
Glidenclamine shine asalin ƙarni na 2 na tushen sulfonylurea. Yana kunna samar da insulin ta hanyar yin aiki a kan masu karɓar beta na pancreas, yana haɓaka matakin insulin na ƙwayoyin tsoka da haɓaka ƙaddamarwar insulin da aiki na insulin dangane da shan gulukos ta hanta da tsokoki, yana rage jinkirin aiwatar da lipolytic a cikin tsarin jijiyar nama.
Metformin wani biguanide ne. Abun yana haɓaka ji na jijiyoyin ƙwayoyin jikin mutum zuwa tasirin insulin, yana rage matakin karɓar glucose a cikin tsarin narkewar abinci kuma yana da sakamako mai hanawa a cikin gluconeogenesis. A sakamakon haka, metabolism na lipid an daidaita shi, kuma ana rage nauyin jiki a cikin masu ciwon suga.
Magungunan yana tattare da yawancin magungunan cututtukan cututtukan cututtukan fata. Yana da sakamako mai cutarwa da kuma cututtukan cututtukan zuciya.
Pharmacokinetics
Glibenclamide ya zama cikakke kuma cikin hanzari ya mamaye ganuwar hanjin narkewa. Lokaci don isa Cmax shine daga minti 60 zuwa 120. An cire ta da bile da kodan a kusan daidai ƙimar. Rabin-rayuwar ya bambanta tsakanin awanni 5-10.
Hakanan ana amfani da Metformin ta hanyoyin hanji. Jiki ba ya rushe. Kodan ya cire ta a kamannin su. Cire rabin rayuwa ya kai 7 awanni.
Alamu don amfani
Ana amfani da maganin don magance nau'in ciwon sukari na 2 na mellitus (insulin-dogara) in babu ingantacciyar tasiri daga monotherapy tare da wasu magungunan hypoglycemic da kuma maganin rage cin abinci.
Ana amfani da maganin don magance nau'in ciwon sukari na 2.
Contraindications
- cututtukan cututtukan cuta masu haɗari waɗanda ke haɗuwa tare da lalata a cikin aikin kodan / hanta ko abubuwan hypoxic;
- rashin haƙuri ɗaya;
- tsananin lalata hanta;
- kamuwa da cutar sankara / precoma;
- lokacin shayarwa da / ko daukar ciki (tare da taka tsantsan);
- nau'in ciwon sukari ketoacidosis;
- matsanancin rashin ƙarfi na jini;
- lactic acidosis;
- nau'in 1 na insulin-dogara da ciwon sukari mellitus.
Yadda ake ɗaukar Glibomet
Ana ɗaukar allunan a baka. Cin abinci yana inganta shan ƙwayoyi. An tsara allurai daban-daban, yin la'akari da yawan ƙwayar ƙwayar cuta na sukari a cikin jini da kuma ƙarfewar ƙwayar carbohydrate.
An tsara allurai daban-daban, yin la'akari da yawan ƙwayar ƙwayar cuta na sukari a cikin jini da kuma ƙarfewar ƙwayar carbohydrate.
Shan maganin don ciwon sukari
Matsakaicin matakin farko shine daga allunan 1 zuwa 3 a kowace rana, sannan a hankali ana kara sashi sosai har sai an sami biyan diyya game da cutar. Matsakaicin maganin yau da kullun shine 5 Allunan a rana.
Sakamakon sakamako na Glybomet
Gastrointestinal fili
- hepatitis;
- jalestice cholestatic;
- amai
- take hakkin ciki;
- kadan tashin zuciya.
Hematopoietic gabobin
- raguwa a matakin sel sel jini, farin farin sel da platelet (da wuya);
- megaloblastic / hemolytic anemia.
Tsarin juyayi na tsakiya
- rage ji na ƙwarai;
- paresis (a cikin mafi yawan lokuta);
- daidaituwa ta hanyar motsa jiki;
- ciwon kai.
Daga gefen metabolism
- akwai haɗarin haɓakar haɓakar jini.
A ɓangaren fata
- rashin ƙarfi ga haske (da wuya),
Cutar Al'aura
- kurji
- kumburi;
- rashin lafiyan rhinitis;
- yawan zafin jiki;
- haɗin gwiwa da ciwon tsoka.
Magungunan zai iya haifar da jin zafi a cikin tsokoki da gidajen abinci.
Tasiri kan ikon sarrafa abubuwan inji
A lokacin shan allunan, akwai yiwuwar hypoglycemia, don haka ya kamata ku guji sarrafa na'ura da injuna.
Umarni na musamman
Lokacin amfani da miyagun ƙwayoyi, dole ne mutum ya bi shawarar likita sosai game da tsarin aikin da allurai. Bugu da ƙari, yayin lokacin jiyya, yana da kyau a bi tsarin abinci, haɓaka tsarin ayyukan motsa jiki da lura da glucose na jini koyaushe.
Haɗin metformin yana haifar da karuwa a cikin yawan lactic acid a cikin jini, wanda zai haifar da irin wannan yanayin mai haɗari kamar lactic acidosis. Sabili da haka, lokacin shan magani, abubuwan haɗari kamar tsawan azumi, yanayin ƙazantar da cutar siga, shan giya da kowane yanayi da ke da alaƙa da hypoxia ya kamata a cire shi.
Don hana lactic acidosis, ya kamata a guji yin azumin nafila a yayin maganin Glibomet.
Yi amfani da lokacin daukar ciki da lactation
An hana. Don tsawon lokacin aikin jiyya daga shayarwa ya kamata ya dena.
Takardar sayen magani na Glybomet ga yara
Allunan ba a amfani da su don kula da marasa lafiya wadanda shekarunsu bai gaza 18 ba.
Yi amfani da tsufa
Ba a buƙatar daidaita sashi ba.
Aikace-aikacen aiki mara kyau
Tare da kulawa na lokaci-lokaci na diuretics da antihypertensive kwayoyi, yakamata a yi taka tsantsan. Kari akan haka, yakamata a kula da keɓantar da keɓaɓɓen mahaifa don marasa lafiya da ƙwayoyin cuta.
Amfani don aikin hanta mai rauni
Marasa lafiya da ke fama da aikin hanta yakamata suyi amfani da magani a hankali.
Marasa lafiya da ke fama da aikin hanta yakamata suyi amfani da magani a hankali.
Glybomet overdose
Alamar halayyar dabi'a: akwai haɗarin haɗarin hypoglycemia da lactic acidosis. Wadannan cututtukan cututtukan suna bayyana ta hanyar bayyanar cututtuka:
- amai
- bari;
- apathy
- raguwa a cikin karfin jini;
- keta lafazin sarari;
- gumi
- karuwar zuciya;
- pallor na fata;
- rawar jiki
- tashin zuciya
- bradyarrhythmia (reflex);
- rashin jin daɗi a cikin rami na ciki;
- tashin hankalin bacci;
- Damuwa
- nutsuwa
Tare da kowane tuhuma na lactic acidosis da hypoglycemia, mai haƙuri yana buƙatar asibiti da gaggawa.
Tare da nau'i mai laushi na hypoglycemia, kuna buƙatar cin ɗan ƙaramin sukari ko sha wani abin sha mai laushi. Wannan zai magance aikin farji.
Hanyar da ta fi dacewa da magani shine hanyar hemodialysis.
Yin hulɗa tare da wasu kwayoyi
Beta-blockers, allopurinol, oxygentetracycline da dicumarol suna haɓaka aikin hypoglycemic na maganin a cikin tambaya.
Haɗuwa tare da cimetidine da sauran abubuwan da ake amfani da su na sulfonylurea suna ƙara haɗarin lactic acidosis.
Amfani da barasa
Barasa a hade tare da miyagun ƙwayoyi na iya haifar da hypoglycemia da disulfiram-like yanayi. Sabili da haka, a lokacin jiyya ya kamata watsi da haɗin su.
Barasa a hade tare da miyagun ƙwayoyi na iya haifar da hypoglycemia da disulfiram-like yanayi.
Analogs
Mai yiwuwa madadin magungunan:
- Siofor;
- Metformin;
- Gluconorm;
- Metglib;
- Forcearfin Metglib;
- Glucovans;
- Karin Gluconorm.
Magunguna kan bar sharuɗan
Kwayoyin hana daukar ciki.
Kwayoyin hana daukar ciki.
Farashin Glibomet
A cikin kantin magunguna a Rasha, allunan da aka rufe da tsada tsakanin 330-360 rubles. don kwali na kwali mai dauke da faranti 4 na kwayoyi 10 a cikin kowane da umarnin amfani.
Yanayin ajiya na miyagun ƙwayoyi
Yanayin ingantacce: bushe, wuri mai duhu mara amfani ga yara, yawan zafin jiki kada ya fi + 25 ° C.
Ranar karewa
Bai wuce watanni 36 ba. Kar a ɗauki allunan ƙarewa.
Mai masana'anta
Kamfanin Jamus "Berlin-Chemie Menarini Group / AG".
Nazarin Glibomet
Nadezhda Khovrina, shekara 40, Moscow
Kafin likita ya tsara wannan maganin na baka, nayi amfani da Glucofage. Koyaya, kusan babu wani amfani daga gare shi. Wadannan kwayoyin suna cikin sauri da kuma rage girman sukari. An tabbatar da wannan ta hanyar nazarin.
Galina Guseva, shekara 45, St. Petersburg
Na dade ina shan maganin. Tasirin yana da tsayayye, in ji shi. Kwanan nan na je wurin likita don gano ko ana iya haɗe shi da magungunan m, tunda ina da shakku na helminthiasis. Likitan ya yarda da liyafar su a lokaci guda. Yanzu zan iya bacci cikin kwanciyar hankali.
