Blocktran GT wani magani ne wanda aka tsara sau da yawa don hawan jini. Babban bukatar wannan maganin yana faruwa ne saboda yanayin dacewa da kuma farashi mai rahusa.
Sunan kasa da kasa mai zaman kansa
Sunan duniya gaba daya na maganin shine Losartan.
Blocktran GT wani magani ne wanda aka tsara sau da yawa don hawan jini.
ATX
Dangane da rarrabuwa da kwayoyi, ATX: C09DA01.
Losartan haɗe tare da diuretics.
Saki siffofin da abun da ke ciki
Ana fitar da maganin a cikin nau'ikan allunan zagaye, kowane ɗayan an lullube shi da wani laushi mai narkewa mai santsi. Launin harsashi na iya zama ruwan hoda, akwai tintin launin shuɗi.
A cikin abun da ke cikin miyagun ƙwayoyi, babban aikin yana aiki ne ta hanyar abubuwan da ke aiki:
- potassium losartan;
- hydrochlorothiazide.
Jerin abubuwan abubuwa masu taimako sun hada da:
- microcrystalline cellulose;
- lactose monohydrate;
- dankalin dankalin turawa;
- povidone;
- magnesium stearate;
- sodium sitaci glycolate;
- colloidal silicon dioxide.
Hadadden losartan da hydrochlorothiazide suna taimakawa rage karfin jini.
Kwalin kwamfutar hannu yana kunshe da kayan aikin masu zuwa:
- polydextrose;
- hypromellose;
- talc;
- matsakaici sarkar triglycerides;
- titanium dioxide;
- dextrin;
- fenti carmine jan ruwa mai narkewa (E120).
Aikin magunguna
Hadadden losartan da hydrochlorothiazide suna da kayan antihypertensive ƙari. Saboda wannan, raguwar hauhawar jini yana faruwa sosai da ƙarfi fiye da lokacin amfani da kowane bangare daban-daban. Kasancewar tasirin diuretic yana ba da gudummawa ga:
- motsawar samar da aldosterone;
- increasedara yawan aikin retsma retin;
- karuwar taro na angiotensin II;
- rage matakan potassium.
Sakamakon abun ciki na losartan, miyagun ƙwayoyi ya kasance ga rukuni na angiotensin mai karɓa na antagonensin 2. Ba ya hana kinase II (wannan enzyme yana da alhakin lalata bradykinin).
Magungunan ba ya haifar da toshewar wasu kwayoyin halittu da tashoshin ion ion waɗanda ke shafar aiki da tsarin jijiyoyin zuciya.
Abubuwa masu aiki suna aiwatar da tsari da yawa a tsarin samar da jini lokaci daya:
- lowers hauhawar jini da matsa lamba a cikin jijiyoyin bugun jini;
- rage taro na norepinephrine da aldosterone a cikin jini na jini;
- rage ƙimar OPSS;
- yana da tasirin diuretic;
- rage bayan kaya;
- yana taimakawa haɓaka haƙuri ga marasa lafiya tare da raunin zuciya zuwa ga aikin jiki.
A wannan yanayin, maganin ba ya haifar da toshe wasu kwayoyin halittar jijiyoyi da kuma tashoshin ion waɗanda ke shafar aiki da tsarin jijiyoyin zuciya.
Hydrochlorothiazide yana da kaddarorin antihypertensive da diuretic. Aikinsa yana da nufin sake fasalin abubuwanda ake samu a cikin abubuwanda ke gudana a cikin ƙyalli. Wataƙila karuwa a cikin taro uric acid. Bayan kulawa ta baka, sashin ya fara aiki bayan sa'o'i 2. Ana samun ingantaccen aiki bayan awa 4. Yawan lokaci na iya bambanta daga awa 6 zuwa 12.
Pharmacokinetics
Tasirin antihypertensive bayan kashi daya na miyagun ƙwayoyi ya isa matsakaicinsa bayan sa'o'i 6. A cikin sa'o'i 24 masu zuwa, sakamako yana raguwa a hankali. Cleaddamar da ƙwayar cutar plasma na ƙwayar cuta da metabolite shine 600 ml / min da 50 ml / min, bi da bi.
Theaukar abu mai aiki yana faruwa ta hanjin kodan da hanjinsa (tare da bile).
Theaukar abu mai aiki yana faruwa ta hanjin kodan da hanjinsa (tare da bile).
Alamu don amfani
An wajabta miyagun ƙwayoyi don cututtukan masu zuwa:
- Hawan jini. Ana amfani da maganin don warkewa da dalilai na prophylactic.
- Hypertrophy na ventricle hagu. An nuna magungunan don rigakafin cututtukan zuciya.
Contraindications
Yin amfani da miyagun ƙwayoyi ba tare da takardar izinin likita ba yana da rauni sosai. Akwai da dama contraindications:
- hypersensitivity zuwa daya ko da yawa abubuwa a cikin abun da ke ciki;
- shekarun yara har zuwa shekaru 18 (ba a yi nazarin tasirin aikin mai aiki a jikin yaran ba);
- kasancewar cututtukan glucose-galactose malabsorption, rashi lactase ko rashin haƙuri a cikin lactose;
- lokacin daukar ciki da lokacin shayarwa;
- mummunan tarihin cutar hanta, cholestasis;
- Cutar Addison;
- rashin ruwa a jiki;
- matsananciyar yanayin jijiya;
- ilimin cututtukan koda (idan keɓancewar creatinine ba ƙasa da 30 ml / min ba);
- rashin lafiya
- hypokalemia refractory;
- hyperkalemia
- ciwon sukari mellitus yana da wuyar sarrafawa.
Tare da kulawa
A gaban wasu cututtukan akwai buƙatar zaɓin sigar kulawa sosai. A lokaci guda, ana kulawa da likita akai-akai don yanayin mai haƙuri. Tare da taka tsantsan, allunan ana wajabta su a waɗannan lambobin:
- stenosis (mitral da aortic);
- lokacin dawowa bayan dasawa da koda;
- hanawar cutar bugun jini;
- kasancewar tsananin bugun zuciya;
- na farko hyperaldosteronism;
- cututtukan cerebrovascular;
- angioedema.
Yadda ake ɗaukar Blocktran GT
Allunan ana samunsu don sarrafa baki. Abinci baya tasiri a kan pharmacokinetics, saboda haka, ana cinye maganin a kowane lokaci mai dacewa: kafin abinci, lokacin abinci, ko bayan hakan.
Ana ɗaukar daidaitaccen ma'aunin yau da kullun a matsayin kwamfutar hannu 1, ana ɗauka sau ɗaya. Akai-akai - lokaci 1 a rana.
A wasu halaye, wannan ƙimar bazai iya haifar da tasirin warkewar da ake so ba, to, a ƙarƙashin kulawar likita, yana yiwuwa a ƙara yawan zuwa allunan 2 a kowace rana. Wannan yakamata ya kasu kashi biyu. Sau da yawa, marasa lafiya da ke fama da hauhawar jini na jijiyoyin jiki irin wannan.
Tare da ciwon sukari
A cikin lura da marasa lafiya da ciwon sukari ya kamata a kai a kai saka idanu kan yanayin haƙuri.
Daga tsarin mai juyayi da gabobin jijiya, kara gajiya mai yiwuwa ne.
Sakamakon sakamako na Blocktran GT
Abubuwan sakamako masu tasowa daga amfani da miyagun ƙwayoyi na iya danganta tsarin tsarin jiki daban. Rashin bayyanuwa yana faruwa a farkon farkon shan allunan, a hankali an kawar da su.
Gastrointestinal fili
Rashin daidaituwa shine maƙarƙashiya da jin zafi a cikin ciki. Mai yiwuwa flatulence, bushe bakin, gastritis, sialadenitis, pancreatitis, hyponatremia.
Hematopoietic gabobin
Daga tsarin jini da jijiyoyi, anaemia anada yawanci a cikin marasa lafiya. Leukopenia, agranulocytosis, thrombocytopenia, da purpura da wuya su faru.
Tsarin juyayi na tsakiya
Daga tsarin juyayi da gabobin jijiyoyi, kara yawan kiba, asma, tsananin rauni, rashin bacci da ciwon kai na yiwuwa.
Commonlyarancin kullun, rashin barci, rauni, damuwa, neuropathy na gefe, rikicewar ƙwaƙwalwar ajiya, rawar jiki daga ƙarshen, damuwa, damuwa a cikin dandano, ringing da tinnitus, conjunctivitis, da asarar hankali.
Daga cikin tasirin sakamako masu illa da suka shafi tsarin urinary, ana kiran cututtukan urinary fili.
Daga tsarin urinary
Daga cikin cututtukan da suka shafi gama gari wanda ake danganta shi da shi shine ake kira urinary fili cututtuka, rage karfin a cikin maza, nakasa aikin koda, da kuma bayyanar urination na peremptory. Hydrochlorothiazide a wasu yanayi na iya haifar da glucosuria, nephritis interstitial.
Daga tsarin numfashi
Wasu marasa lafiya suna koka game da ambaliyar hanci, tari da alamu na kamuwa da cuta da ke shafar jijiyar tashin zuciya (a tsakanin su sinusitis da pharyngitis). Irin wadannan bayyanar cututtuka sukan kasance tare da zazzabi.
Commonarancin yau da kullun sune rhinitis, mashako, ƙarancin numfashi, huhun ciki, huhu.
A ɓangaren fata
Shan magungunan na iya haifar da bushewar fata, daukar hoto, hyperemia, yawan shan ruwa, jiki mai guba, fasalin fata na lupus erythematosus.
Daga tsarin musculoskeletal
Ana yawan gano tashin hankali, ciwon baya, myalgia, zafi a kafafu da kirji. Arthralgia, fibromyalgia da amosanin gabbai ana ɗaukar alamun bayyanai.
Daga tsarin musculoskeletal bayan shan miyagun ƙwayoyi, yawancin lokuta ana gano raɗaɗi.
Daga tsarin zuciya
Sakamakon sakamako a yayin magani na iya zama:
- karuwar zuciya;
- orthostatic hypotension;
- arrhythmia;
- angina pectoris;
- bradycardia;
- necrotizing vasculitis;
- zafi a zuciya.
Cutar Al'aura
Allergy amsawar rashin lafiyar jiki ce ga wani ɓangaren miyagun ƙwayoyi. Yana haɗuwa tare da itching, urticaria, fitsari, angioedema.
Tasiri kan ikon sarrafa abubuwan inji
Yayin gudanar da aikin jiyya tare da miyagun ƙwayoyi, marasa lafiya na iya fuskantar tasirin sakamako irin su rashin barci, rage yawan natsuwa da jijiyoyin gani da ƙaiƙayi da asarar hankali. A saboda wannan dalili, dole ne a kula sosai lokacin tuki da kuma shiga cikin wasanni masu haɗari.
Umarni na musamman
Blocktran yana da ikon haɓaka taro na ƙwayoyin serin creatinine da urea na jini. Wadannan canje-canje sau da yawa suna faruwa ne a cikin marasa lafiya da aka gano tare da stenosis na kodan ko na katako.
Allergy amsawar rashin lafiyar jiki ce ga wani ɓangaren miyagun ƙwayoyi.
Yi amfani da lokacin daukar ciki da lactation
A magani, babu bayanai kan tasirin wannan maganin akan lafiya da yanayin tayin. A wannan yanayin, maganin yana shafar RAAS, wanda a cikin ka'idar na iya haifar da ci gaban nakasa da mutuwar tayi yayin ɗaukar maganin a cikin digiri na biyu da na uku.
Idan ya zama dole a yi amfani da maganin a cikin kula da mata masu shayarwa, likitoci sun bada shawarar hana lactation, tunda madarar nono tana dauke da karamin adadin losartan.
Alƙawarin tariyar Blocktran GT
Ba a samun bayanai game da tasiri na magani a lokacin ƙuruciya ba. Don wannan, ba a ba wa yara magani.
Yi amfani da tsufa
Sakamakon gwaji na asibiti, babu wani hatsari yayin ɗaukar daidaitattun matakan maganin. Haɓaka kashi ba da shawarar ba.
Masana sun haramta amfani da wannan magani yayin shayarwa.
Aikace-aikacen aiki mara kyau
A wasu halaye, shan miyagun ƙwayoyi ya haifar da matsala a cikin kodan. Anyi bayanin wannan ta hanyar hanawar RAAS, wanda ke faruwa bayan ɗaukar kwayoyin. Irin waɗannan cututtukan na ɗan lokaci ne kuma an dakatar dasu bayan dakatar da magani.
Tare da taka tsantsan, ya kamata a ba da magunguna ga mutanen da ke fama da cutar sananniya ta hanji.
Aikace-aikace don aikin hanta mai rauni
Sakamakon karatun likitanci, karuwar losartan a cikin jinin marasa lafiya da aka gano da cutar hanta. A saboda wannan dalili, an rage sashi don aikin hanta mai rauni.
Doaukar da yawa na Blocktran GT
Wucewa da maganin da likita ya umarta yakan haifar da yawan shan magunguna. Ana nuna shi ta bayyanar ƙananan jini, tachycardia, bradycardia. Rashin wucewar hydrochlorothiazide yana haifar da hypochloremia, hypokalemia, hyponatremia. Wataƙila ƙara arrhythmias.
Sakamakon karatun likitanci, karuwar losartan a cikin jinin marasa lafiya da aka gano da cutar hanta.
Don kwantar da yanayin mara lafiyar, likitoci suna yin diureis mai ƙarfi kuma suna gudanar da magani na alama. A wannan yanayin, hemodialysis ba shi da tasiri.
Yin hulɗa tare da wasu kwayoyi
Angiotensin II mai karɓar maganin antagonist a wasu halaye an wajabta shi azaman ɓangaren hadadden magani. A wannan yanayin, sinadarin losartan yana hulɗa daban da sauran kwayoyi:
- Haɗawa tare da Aliskiren ba da shawarar ba saboda haɗarin ci gaba da cututtukan cututtukan ƙwaƙwalwa a cikin aikin kodan da hauhawar jini.
- Tare da masu hana ACE. Sau da yawa akwai bayyanar lalacewa ta koda, syncope, babban hypotension ko hyperkalemia.
- Amfani kai tsaye tare da kwantar da hankali ko wakilan kwantar da hankula suna haifar da haɓaka juna game da aikin kwayoyi.
- Tare da isar da sinadarin potassium, da yawa daga cikin mara lafiya suna haɓaka matakan potassium a cikin jiki.
- Tare da fluconazole da rifampicin, sakamakon losartan yana raguwa.
- Tare da barbiturates da narcotic analgesics. Akwai haɗarin haɗari na orthostatic hypotension.
- Tare da magungunan hypoglycemic. Daidaitawar sashi ya zama dole, tunda an rage tasirin magunguna.
Amfani da barasa
Tabletsaukar Allunan ba a cika son su tare amfani da giya ba. Irin waɗannan ayyukan suna iya haifar da mummunan sakamako masu illa. Hydrochlorothiazide a gaban ethanol zai iya haifar da tashin hankali na orthostatic.
Analogs
Magungunan suna da alamun analogues da yawa waɗanda kamfanonin Rasha da na kasashen waje ke samarwa. Daga cikinsu akwai kwayoyin halitta da magunguna masu kama da wannan:
- Vazotens H;
- Lorista N;
- Gizaar Forte;
- Presartan H;
- Simartan-N;
- Gizortan.
Magunguna kan bar sharuɗan
Zaku iya siye magani ta hanyar takardar sayan magani.
Zan iya siye ba tare da takardar sayan magani ba
Ana samun magunguna daga rukuni na angiotensin II antagonists antagonists ne kawai kan takardar sayan magani.
Blocktran GT Farashin
Kudin maganin yana dogara da sashin allunan. Farashin kimantawa a cikin kantin magunguna a Moscow daga 220 rubles. kowace fakiti (30 Allunan).
Yanayin ajiya na miyagun ƙwayoyi
Wurin don adana magungunan yakamata ya bushe, ya kiyaye daga hasken rana kai tsaye. Yanayin zafi - ba ya fi + 25 ° С.
Ranar karewa
Amincewa da yanayin ajiya na miyagun ƙwayoyi, rayuwar shiryayye na allunan ya kai watanni 24 daga ranar da aka sake su. Bayan wannan lokaci, an haramta yin amfani da miyagun ƙwayoyi.
Mai masana'anta
Ana samar da maganin ne ta hanyar Pharmstandard-Leksredstva OJSC. Kamfanin magunguna yana cikin Kursk a adireshin: st. Kashi Na Biyu, 1a / 18.
Blocktran GT sake dubawa
Alexander, dan shekara 48, Volgograd
An dauki maganin a matsayin wani ɓangare na cikakken magani bayan fama da matsalar hauhawar jini. A farkon zamanin, ciwon kai da ƙananan gajiya ya tashi. Likitan ya ba da shawarar kar a karba. A cikin sati na biyu, sai an daina jin sakamako masu illa. An kammala aikin gyaran ginin.
Tatyana, ɗan shekara 39, Khabarovsk
Na dade ina fama da cutar hawan jini. Magungunan suna aiki da sauri kuma yadda ya kamata. Kafin wannan, likitan ya ba da wasu kwayoyin magani, amma ba su kawo wani sakamako ba.
