Yanumet magani ne na baki wanda ake amfani da shi wajen maganin cututtukan cututtukan daji wadanda ba na insulin-insulin ba. Shan maganin yana taimaka wajan daidaita matakan glucose na jini na yau da kullun, yana hana ci gaban cutar da inganta ingantacciyar rayuwa ga marasa lafiya.
Sunan kasa da kasa mai zaman kansa
Metformin + Sitagliptin.
Yanumet magani ne na baki wanda ake amfani da shi wajen maganin cututtukan cututtukan daji wadanda ba na insulin-insulin ba.
ATX
A10BD07.
Saki siffofin da abun da ke ciki
Ana amfani da miyagun ƙwayoyi ta kasuwanci a cikin nau'ikan allunan Alllong tare da farfajiya na biconvex, an rufe shi da fim ɗin shiga cikin haske mai ruwan hoda, ruwan hoda ko launi ja (dangane da sashi). An shirya maganin a cikin fakiti mai bakin ciki guda 14. Fakitin takarda mai kauri ya ƙunshi fitsari 1 zuwa 7.
Abubuwan da ke aiki da Yanumet sune sitagliptin a cikin nau'in phosphate monohydrate da metformin hydrochloride. Abun da ke cikin sitagliptin a cikin shirye-shiryen koyaushe ɗaya ne - 50 MG. Ctionarancin kashi na metformin hydrochloride na iya bambanta kuma shine 500, 850 ko 1000 a cikin kwamfutar 1.
A matsayin abubuwanda ke taimakawa, Yanumet ya ƙunshi lauryl sulfate da sodium stearyl fumarate, povidone da MCC. An yi harsashi da kwamfutar hannu daga macrogol 3350, polyvinyl barasa, titanium dioxide, baƙar fata da baƙin ƙarfe jan ƙarfe.
An shirya maganin a cikin fakiti mai bakin ciki guda 14.
Aikin magunguna
Magungunan ƙwayar cuta shine wakili mai haɗuwa wanda abubuwan aiki masu aiki suna da haɗin gwiwa (haɗin gwiwa) sakamako na hypoglycemic, yana taimakawa marasa lafiya da nau'in ciwon sukari na II na mellitus suna kiyaye matakan glucose na al'ada.
Sitagliptin, wanda shine ɓangare na miyagun ƙwayoyi, shine mai hana dipeptidyl peptidase-4 inhibitor mai mahimmanci. Lokacin da aka sha shi a baki, yana haɓaka abun cikin glucagon-kamar peptide-1 da glucose-peulinide-insulinotropic-insulinotropic peptide - kwayoyin da suke haɓaka haɓakar insulin kuma suna ƙara ɓoyewa a cikin ƙwayoyin ƙwayar cuta ta sau 2-3. Sitagliptin yana ba ku damar kula da matakan sukari na al'ada na plasma a cikin kullun kuma yana hana ci gaban glycemia kafin karin kumallo da bayan cin abinci.
Ayyukan sitagliptin yana ƙaruwa ta hanyar metformin - wani abu mai ɗauke da jini wanda ke da alaƙa da biguanides, wanda ke rage haɗarin sukari a cikin jini ta hanyar dakatarwa ta hanyar 1/3 aiwatar da samar da glucose a cikin hanta. Bugu da ƙari, lokacin ɗaukar metformin a cikin marasa lafiya da ke dauke da ciwon sukari na 2, akwai raguwa a cikin shan glucose daga ƙwayar narkewa, haɓaka yanayin jijiyoyin jiki zuwa insulin da kuma haɓaka aikin fatima acid.
Pharmacokinetics
Matsakaicin yawan plasma na sitagliptin ana lura da sa'o'i 1-4 bayan sarrafa bakin magana na kashi ɗaya, metformin - bayan awa 2.5. A bioavailability na abubuwa masu aiki lokacin amfani da Yanumet akan komai a ciki shine kashi 87% da 50-60%, bi da bi.
Yin amfani da sitagliptin bayan cin abinci ba ya shafar sha daga cikin narkewar abinci. Yin amfani da metformin a lokaci guda tare da abinci yana rage ƙimar sha kuma yana rage yawan damuwa a cikin plasma da 40%.
Fitar sitagliptin yana faruwa ne musamman da fitsari. Wani karamin sashi daga ciki (kusan 13%) yana barin jiki tare da abubuwan da ke cikin hanji. Kodan ya gama cire komai da kodan.
Kodan ya gama cire komai da kodan.
Alamu don amfani
An wajabta magani don kamuwa da cutar siga 2. An nuna shi azaman ƙari ga abinci da motsa jiki ga marasa lafiya waɗanda:
- rashin iya sarrafa matakan glucose tare da yawan allurai na metformin;
- Ya rigaya ya sha magungunan hade wadanda suka dogara da kayan aikin da ya hada Yanumet, kuma magani ya samar da sakamako mai amfani;
- far yana da mahimmanci tare da abubuwan da suka samo asali na sulfonylurea, Ponγ agonists, ko insulin, tunda shan metformin a hade tare da waɗannan kwayoyi baya bada damar cimma iko na dole akan maganin glycemia.
Contraindications
Ba a amfani da magani wajen maganin marasa lafiya waɗanda ke da cututtukan da ke biye ko yanayin:
- nau'in ciwon sukari na mellitus;
- ketoacidosis, tare da mai ciwon sukari ko ba tare da shi ba;
- lactic acidosis;
- aikin lalata hanta;
- gazawar renal, a cikin abin da keɓancewar creatinine ba ƙasa da 60 ml minti ɗaya ba;
- rashin ruwa a jiki.
- mawuyacin halin pathologies na asalin cutar;
- jihar rawar jiki;
- lura da iodine-dauke da abubuwan bambanci;
- cututtukan cututtukan da ke haifar da ƙarancin oxygen a cikin jiki (bugun zuciya, infarction na zuciya, rashin ƙarfi na numfashi, da dai sauransu);
- asarar nauyi tare da rage yawan kalori (har zuwa 1 dubu kcal a kowace rana);
- barasa;
- giya barasa;
- lactation
- ciki
- karamin shekaru;
- mutum rashin jituwa ga abubuwan da aka gabatar a cikin abubuwan da ke jikin allunan.
Tare da kulawa
Lokacin amfani da Yanumet, yakamata ayi amfani da tsofaffi da waɗanda ke fama da rauni na koda.
Yadda ake ɗaukar Yanumet
Ana amfani da miyagun ƙwayoyi sau biyu a rana tare da abinci, a wanke da wasu sips na ruwa. Don rage yiwuwar mummunan sakamako daga narkewa, ana fara jiyya tare da mafi ƙarancin kashi, sannu a hankali yana haɓaka shi har sai an sami sakamako na warkewa.
Shan maganin don ciwon sukari
An zabi sashi na Yanumet ga kowane mara lafiya daban-daban, la'akari da tasirin magani da kuma haƙuri na magani. Matsakaicin adadin yau da kullun kada ya wuce 100 MG.
Sakamakon sakamako na Yanumet
Yayin shan maganin, mai haƙuri na iya fuskantar tasirin da ba a so ta tsokanar sitagliptin da metformin. Idan sun faru, ya zama dole mu guji ƙarin maganin kuma ziyarci likita da wuri-wuri.
Idan akwai wani sakamako masu illa, ya zama dole a guji kara murmurewa sannan a ziyarci likita da wuri-wuri.
Gastrointestinal fili
Abubuwan haɗari masu illa daga tsarin narkewa shine galibi ana lura da su a matakin farko na far. Waɗannan sun haɗa da jin zafi a cikin jijiyoyin ciki, tashin zuciya, amai, haɓakar gas a cikin hanji, zawo, maƙarƙashiya. Shan kwayoyin magani tare da abinci na iya rage mummunan tasirin su akan tsarin narkewa.
A cikin marasa lafiya da ke karbar magani tare da Yanumet, ci gaban pancreatitis (basur ko cutar necrotizing), wanda ba zai haifar da mutuwa ba.
Daga gefen metabolism
Idan aka zaɓi sashi ba daidai ba, mai haƙuri na iya fuskantar matsalar rashin ƙarfi, wanda ya ƙunshi raguwar haɓakar sukari na jini. Lokaci-lokaci, shan magani na iya haifar da lactic acidosis, wanda ke nuna kanta a cikin nau'i na raguwa a cikin matsin lamba da zafin jiki, jin zafi a ciki da tsokoki, ƙarancin bugun jini, rauni da gajiya.
A ɓangaren fata
A cikin maganganun da ke cikin rashi, a cikin marasa lafiya suna shan magani na hypoglycemic, ƙwararrun likitoci suna binciken vasculitis na fata, ƙwararrun pemphigoid, guba mai narkewa a cikin ƙwayar cuta.
Daga tsarin zuciya
Magungunan suna da haƙuri da kyau ga mutanen da ke fama da cututtuka na zuciya da jijiyoyin jini. Lokaci-lokaci, suna iya fuskantar raguwa a cikin bugun zuciya, wanda ke faruwa sakamakon lactic acidosis.
Magungunan suna da haƙuri da kyau ga mutanen da ke fama da cututtuka na zuciya da jijiyoyin jini.
Cutar Al'aura
Tare da rashin jituwa ga abubuwan da ke cikin maganin, mutum na iya haɓaka halayen rashin lafiyar ta hanyar cututtukan urtikaria, itching da fatar kan fata. Yayin yin jiyya tare da Yanumet, da yiwuwar faruwar cututtukan fata, fatar mucous membranes, wanda ke da haɗari ga rayuwa, ba a yanke hukunci ba.
Tasiri kan ikon sarrafa abubuwan inji
Magungunan zai iya haifar da nutsuwa, don haka a duk lokacin da aka gudanar da shi an bada shawarar ƙin fitar da motar kuma ta yi aiki tare da sauran hanyoyin haɗari.
Umarni na musamman
A yayin jiyya tare da Yanumet, marasa lafiya suna buƙatar biye da tsarin abinci tare da rarraba nau'ikan carbohydrates a cikin kullun kuma a kula da metabolism metabolism a jiki.
Yi amfani da lokacin daukar ciki da lactation
Kada a sha magani a yayin ɗaukar yaro, tunda bayanai akan amincinsa a wannan lokacin babu su. Idan wata mace da take karbar magani tare da Yanumet ta sami juna biyu ko kuma ta yi niyyar yin hakan, to tana bukatar ta daina shan ta kuma ta fara maganin insulin.
Amfani da maganin bai dace da shayar da nono ba.
Amfani da maganin bai dace da shayar da nono ba.
Wa'adin Yanumet ga yara
Nazarin da ke tabbatar da amincin miyagun ƙwayoyi a cikin yara da matasa ba a aiwatar da su ba, saboda haka, bai kamata a tsara shi ga marasa lafiya waɗanda shekarunsu ba su wuce shekara 18 ba.
Yi amfani da tsufa
Tunda kayan aikin Yanumet sun kebe a cikin fitsari, kuma a cikin tsufa, aikin motsin yara ya ragu, yakamata a yi wa likitancin magani a hankali ga mutane sama da shekara 60.
Aikace-aikacen aiki mara kyau
An sanya maganin a cikin marasa lafiya da ke fama da matsanancin rauni ko kuma matsakaici na rashin nasara na koda. Mutanen da ke da raguwar matsakaici a cikin aikin koda ya kamata su sha maganin a ƙarƙashin kulawar kwararrun.
Amfani don aikin hanta mai rauni
An hana yin nadawa.
Bai kamata a rubuta wa marasa lafiya da ƙwayar cutar hanta magani ba.
Doaƙƙar yawa daga Yanumet
Idan kashi ya wuce, mai haƙuri na iya haɓaka lactic acidosis. Don kwantar da yanayin, sai a yi masa gwaji tare da matakan ɗaukar jinin tsarkake jini.
Yin hulɗa tare da wasu kwayoyi
Haɗarin miyagun ƙwayoyi tare da diuretics, glucagon, hana hana haihuwa, phenothiazines, corticosteroids, isoniazid, antagonists na calcium, nicotinic acid da hormones thyroid suna haifar da rauni ga aikinsa.
An inganta tasirin hypoglycemic na miyagun ƙwayoyi lokacin da aka yi amfani da su tare da magungunan anti-mai kumburi marasa ƙarfi, MAO da ACE inhibitors, insulin, sulfonylurea, oxytetracycline, clofibrate, acarbose, beta-blockers da cyclophosphamide.
Amfani da barasa
Haramun ne a sha giya yayin jiyya tare da Yanumet.
Analogs
Tsarin kwatancen maganin shine Valmetia. Ana samar da wannan magani a cikin nau'in kwamfutar hannu kuma yana da kayan aiki iri ɗaya kuma sun dace da Yanumet. Hakanan, ƙwayar tana da zaɓi mai ƙarfi - Yanumet Long, wanda ya ƙunshi 100 MG na sitagliptin.
Idan babu wani sakamako mai warkewa daga Yanumet, likita zai iya ba da izinin wakilai na hypoglycemic ga mai haƙuri, a cikin abin da ake haɗuwa da metformin tare da sauran abubuwan hypoglycemic. Wadannan magungunan sun hada da:
- Avandamet;
- Amaryl M;
- Douglimax;
- Galvus;
- Vokanamet;
- Glucovans, da sauransu.
Magunguna kan bar sharuɗan
A gaban takardar sayan magani.
Zan iya siye ba tare da takardar sayan magani ba
Kuna iya siyan magungunan ba tare da takardar sayen magani ba kawai a cikin kantin magani na kan layi.
Farashi don Yanumet
Kudin magani ya dogara da sashi da adadin allunan a cikin fakitin. A cikin Rasha, ana iya siyan shi don 300-4250 rubles.
Yanayin ajiya na miyagun ƙwayoyi
An yaba da maganin a cikin wani wuri mai kariya daga hasken rana kuma ba a isa ga ƙananan yara. Yawan ma'aunin ajiya na allunan kada ya wuce + 25 ° C.
A cikin kantin magani, ana iya siye magunguna tare da takardar sayan magani.
Ranar karewa
Watanni 24 daga ranar da aka ƙera su.
Mai masana'anta
Kamfanin Kamfanin magunguna Merck Sharp & Dohme B.V. (Netherlands).
Nazarin likitoci game da Yanumet
Sergey, 47 shekara, endocrinologist, Vologda
Ga marasa lafiya da ke fama da rashin lafiyar insulin-da ke fama da cutar kansa, galibi ina ba da wannan magani, tunda an tabbatar da ingancinsa yau. Yana sarrafa glucose da kyau kuma kusan ba ya haifar da sakamako masu illa, koda tare da tsawon jiyya.
Anna Anatolyevna, 53 years old, endocrinologist, Moscow
Ina ba da shawarar yin magani tare da Janumet ga marasa lafiya waɗanda ba sa iya daidaita sukarin jininsu tare da Metformin kaɗai. Hadaddun abubuwan da ke tattare da miyagun ƙwayoyi yana taimakawa mafi kyawun alamun alamun glucose. Wasu marasa lafiya suna jin tsoron shan ƙwayar saboda haɗarin cututtukan jini, amma binciken da aka yi kwanan nan ya nuna cewa yuwuwar faruwar hakan daidai yake a tsakanin mutanen da suka karɓi kwaya da placebo. Kuma wannan yana nufin cewa miyagun ƙwayoyi ba su da tasiri a kan ci gaban cututtukan cututtukan zuciya. Babban abu shine a zabi madaidaicin sashi.
Ya kamata a ba da magani a hankali ga mutanen da shekarunsu suka wuce 60.
Neman Masu haƙuri
Lyudmila, shekara 37, Kemerovo
Ina jinya tare da Janomat kusan shekara guda. Ina ɗaukar mafi karancin kashi 50/500 MG da safe da maraice. A cikin watanni 3 na farko na jiyya, ya yiwu ba kawai don ɗaukar ciwon sukari a ƙarƙashin kulawa ba, har ma don rasa kilogiram 12 na nauyi. Na haɗu da magani tare da abinci da matsakaiciyar motsa jiki. Yanzu ina jin daɗi sosai fiye da magani.
Nikolay, ɗan shekara 61, Penza
Ya kasance yana shan Metformin don ciwon sukari, amma sannu a hankali ya daina taimakawa. Masana ilimin kimiyya na endocrinologist sun wajabta jiyya tare da Yanumet kuma suka ce wannan magani shine maganin da yafi karfi na abinda na sha a baya. Na kwashe shi tsawon watanni 2, amma har yanzu sukuna sukari. Ba na ganin kyakkyawan sakamako daga jiyya.
