Melfor ya kafa kansa a cikin kasuwar magunguna saboda tasirin gaske game da aikin tsarin zagayawa. A cikin layi daya, ana amfani da maganin don kawar da gajiya mai rauni wanda ya samo asali daga yanayin damuwa na jiki da halin kirki. Magungunan yana taimakawa wajen daidaita samarda jini zuwa yankin ischemic na myocardium, kwakwalwa, tare da cututtukan dystrophic a cikin retina na etiologies daban-daban.
Sunan kasa da kasa mai zaman kansa
Meldonium.
Melfor ya kafa kansa a cikin kasuwar magunguna saboda tasirin gaske game da aikin tsarin zagayawa.
ATX
C01EB.
Saki siffofin da abun da ke ciki
Ana amfani da maganin a cikin siffofin sashi daban-daban:
- Maganin allura.
- Syrup na baka.
- Capsules don amfani da baka.
Magani
1 ml na nau'in sashi na ruwa ya ƙunshi 100 MG na aiki fili - meldonium, narkar da cikin ruwa mai bakararre don yin allura. Maganin don daidaitawa, cikin intramuscularly da intravenously ana siyar dashi cikin gilashin ampoules tare da ƙara 5 ml a kowane yanki ko 2, 20, 50, 100 raka'a a cikin ɗaɗɗun farka.
Kafurai
Farin fata mai rufi tare da wuya gelatin m harsashi dauke da foda cakuda 250 MG meldonium MG. Magungunan na miyagun ƙwayoyi an kulle su a cikin blisters na fuloti 10-30 kowannensu.
Aikin magunguna
Magungunan sunadarai ne na gamma-butyrobetaine. Magungunan an yi niyya don haɓaka metabolism gaba ɗaya. Hanyar aiwatarwa ta dogara da hanawar enzyme gamma-butyrobetaine hydroxynase, sakamakon abin da ya haifar da carnitine da shigarwar tsararren sarkar acid mai tsayi cikin tsarin salula. Magungunan yana hana tara nau'ikan kitse mai yawa (abubuwan da aka samo na acyl coenzyme A da acyl carnitine) waɗanda basu sami halayen shaye-shaye na jiki ba.
Magungunan an yi niyya don haɓaka metabolism gaba ɗaya.
Tare da raguwa a cikin ƙwayar plasma na carnitine, farawar gamma-butyrobetaine yana farawa, wanda ke da tasirin natsuwa a jikin bangon jijiyoyin jiki. A lokaci guda, abu mai aiki yana ba da gudummawa ga:
- karuwa da aiki;
- raguwa gajiya akan asalin damuwa da damuwa ta jiki;
- haɓaka aikin bugun zuciya;
- theara haɓakar gwiwa da amsawar rigakafi.
A gaban ischemia, meldonium yana da hannu a cikin maido da samar da jini zuwa yankin da ake gudanar da cututtukan cuta da jigilar makamashi. Tissues suna samun damar yin amfani da iskar oxygen ta hanyar kunna glycolysis a lokaci guda a ƙarƙashin yanayin anaerobic. Idan mummunan cututtukan zuciya da jijiyoyin jini ya faru, miyagun ƙwayoyi suna taɓarɓare wuraren necrotic kuma yana rage lokacin murmurewa. Tare da haɓakar rashin ƙarfin zuciya, juriya na myocardial zuwa karuwar damuwa yana ƙaruwa, da yiwuwar angina pectoris yana raguwa, ƙimar zuciya tana ƙaruwa.
A cikin mummunan yanayin ko mai saurin kamuwa da cuta na ƙwaƙwalwa yayin liyafar Melfort, microcirculation an daidaita shi a cikin yanayin cutar cuta ta ischemic. Jini yana farawa da rarrabawa tsofaffin fitsarin da ya shafa.
Ana amfani da Meldonium a cikin aikin likita don magance dystrophy na jijiya na opic da tasoshin fundus. A lokaci guda, miyagun ƙwayoyi suna motsa aikin da tsarin juyayi na tsakiya kuma yana kawar da rikicewar jijiyoyi a cikin marasa lafiya da ke fama da alamun karbowar barasa da barasa.
Pharmacokinetics
Bayan gudanar da baki, meldonium yana farawa da ƙwaƙwalwar ƙwaƙwalwa ta microvilli na ƙananan hanji na hanji. A bioavailability bayan kashi ɗaya shine 78%.
Bayan gudanar da baki, meldonium yana farawa da ƙwaƙwalwar ƙwaƙwalwa ta microvilli na ƙananan hanji na hanji.
Idan ya shiga cikin jijiya na jijiyoyin jiki, matsakaicin aikin mai aiki a cikin jini yana gyarawa bayan sa'o'i 1-2. Meldonium yana ɗaukar canji a hepatocytes tare da samuwar samfuran 2 na rayuwa mai aiki wanda aka keɓe ta hanjin kodan. Kashe rabin rabin rayuwa kai tsaye ya dogara ne da matakan da aka karɓa - tare da daidaitaccen kashi na 250 mg na meldonium shine 3-6 hours.
Alamu don amfani
Ana amfani da maganin ta baka da kuma allura a cikin jijiya don magani a waɗannan halayen:
- hanzarta farfadowar nama bayan tiyata;
- ficewa daga asalin cutar shan giya;
- hadaddun hanyoyin magance cututtukan zuciya na zuciya, cututtukan zuciya, tare da raunin myocardial infarction da angina pectoris;
- gazawar hormonal tare da cardiomyopathy;
- rage aiki;
- hadewar magani na hatsarin cerebrovascular;
- rigakafin bugun jini, karancin hanji;
- damuwa ta jiki, musamman tsakanin 'yan wasa.
Ana amfani da allurar parabulbar a gaban raunin cuta a cikin retina, thrombosis, basur na asali daban-daban, retinopathy, hemophthalmus.
Contraindications
An haramta yin amfani da miyagun ƙwayoyi don amfani da marasa lafiya tare da karuwar matsa lamba na intracranial a kan asalin rikice-rikice na ƙwayoyin cuta na hanji da jijiyoyin mahaifa, tare da tashin hankali na nama zuwa meldonium.
Tare da kulawa
An ba da shawarar yin hankali tare da magani na dogon lokaci ga marasa lafiya da cututtukan hanta da koda.
Yadda ake ɗaukar Melfort
Ana bada shawarar a sha maganin shafawa a baki kafin abinci da safe sabili da sakamako mai ban sha'awa.
Ana bada shawarar a sha maganin shafawa a baki kafin abinci da safe sabili da sakamako mai ban sha'awa.
| Cutar | Tsarin warkewa | |
| Magani don allura | Kafurai | |
| Activityarfafa aikin jiki | Single kashi - na ciki na 5 ml. Tsawan lokacin magani shine kwanaki 10-14. Idan ya cancanta, za a iya maimaita karatun bayan makonni 2-3. | 250 mg sau 4 a rana don kwanaki 10-14. Ana maimaita warkarwa bayan makonni 2-3 idan ya cancanta. An ba da shawarar 'yan wasa su dauki 0.5-1 g na miyagun ƙwayoyi sau 2 a rana kafin motsa jiki. A shirye-shiryen gasar, hanya ce ta lura tsawon kwanaki 14-21, a wasu ranakun - daidaitaccen lokacin. |
| A matsayin wani ɓangare na haɗakar maganin cututtukan zuciya | A / a cikin 5-10 ml na tsawon makonni 2. |
|
| Matsanancin lokaci na hatsarin ischemic cerebrovascular | Ana bayar da allurar ne kawai tare da abubuwan fashewa. A ƙarshen allurar, an wajabta gudanar da maganin maganin; gabatarwar iv 5 ml kowace rana don kwanaki 7-10. Idan akwai rashin wadatar haila, to ya zama dole a allurar da maganin har tsawon kwana 10-14. | Farjin yana wuce makonni 4-6, lokacin da kuke buƙatar shan 500 MG na miyagun ƙwayoyi kowace rana. |
| Dauke da cutar barasa | 5 ml ana allura a cikin jijiya sau biyu a rana. Aikin jiyya shine kwanaki 7-10. | 500 MG sau 4 a rana don kwanaki 7-10. |
| Cututtaccen ƙwayar cuta ga tasoshin asusun | Inje na 0.5 ml retrobulbar ko a cikin yankin a ƙarƙashin conjunctiva na kwana 10. | Capsules ba zai ba da tasirin warkewar da ake so ba. |
Tare da ciwon sukari
Magungunan ba ya tasiri a asirce na aikin ƙwayoyin beta da ke cikin ƙwayar jini, sabili da haka, ba a buƙatar ƙarin gyara ga marasa lafiya da ciwon sukari.
Magungunan ba ya tasiri a cikin ayyukan asirin ƙwayoyin beta na cututtukan fata da sukari na jini.
Side effects Melfora
Sakamakon mara kyau daga gabobin jiki da tsarin daban-daban na iya bayyana saboda rashin kyakkyawan tsarin allura da kuma watsi da shawarwarin likita.
Gastrointestinal fili
A cikin lokuta masu wuya, alamomin dyspeptik, tashin zuciya, ciwon ciki, zawo, zazzaɓi, da maƙarƙashiya na iya faruwa.
Hematopoietic gabobin
Tare da gudanarwa na baka, akwai haɗarin raguwa a adadin abubuwan da aka kafa cikin jini. Idan mummunan halayen ya faru a cikin tsarin jijiyoyin jini, tachycardia, hauhawar jini, ko hauhawar jijiya na iya faruwa.
Tsarin juyayi na tsakiya
Zai yiwu ci gaban tashin hankali na psychomotor.
Cutar Al'aura
A mafi yawan lokuta, haɓakar girgiza ƙwayar cutar anaphylactic da edema Quincke ba ta kai ba. Marasa lafiya na iya fuskantar fatar jiki, ƙaiƙayi, da erythema.
Tasiri kan ikon sarrafa abubuwan inji
A lokacin da ake amfani da maganin ƙwayar cuta, tuki, matsanancin motsa jiki, yin aiki tare da na'urori masu rikitarwa da sauran ayyukan da ke buƙatar taro da ƙwarewar motsa jiki an yarda.
Umarni na musamman
A yayin gudanar da karatun asibiti da kuma kwarewar amfani da maganin ta hanyar likitocin zuciya a aikin likitanci, an gano cewa meldonium ba zai iya mayar da ayyukan jikin gaba daya cikin rashin wadatar zuciya ba.
Yi amfani da tsufa
Ba a buƙatar mutanen da suka wuce shekaru 60 don yin canje-canje ga tsarin kulawa.
Aiki yara
Ba'a bada shawarar amfani da capsules da mafita don amfani ba har zuwa 18 shekara saboda ƙarancin ingantaccen bincike da bayanai game da tasirin meldonium akan haɓaka da haɓaka yaro a cikin ƙuruciya, lokacin samartaka. Ba a amfani da syrup har sai an shekara 12.
Yi amfani da lokacin daukar ciki da lactation
Akwai haɗarin shiga ciki na meldonium ta hanyar shinge na mahaifa, sakamakon abin da kefar babbar kyallen takarda da gabobin jiki a lokacin haɓakar tayi. An wajabta magungunan ga mata masu juna biyu ne kawai idan akwai haɗari ga rayuwar mai haƙuri wanda ya zarce hadarin cutar kansa ta cikin mahaifa.
A lokacin jiyya, wajibi ne a daina shayarwa.
Aikace-aikacen aiki mara kyau
Dole ne a kula sosai yayin shan magungunan a kan asalin aikin koda wanda ba daidai ba.
Amfani don aikin hanta mai rauni
Ba'a bada shawarar maganin ga mutanen da ke fama da ciwon hanta mai yawa.
Fiye da Melfora
Tare da kashi ɗaya na babban kashi, akwai haɗarin raguwa a cikin karfin jini, tsananin farin ciki, tachycardia arterial, rauni na tsoka, da ciwon kai. Ana yin magani na mara haƙuri don kawar da alamun asibiti na yawan abin sama da ya kamata. Lokacin ɗauka ta baki (capsules, syrup), ana ba da shawarar cewa a ba wa mai haƙuri aikin gawayi don rage sha a cikin ƙananan hanjin.
Yin hulɗa tare da wasu kwayoyi
Tare da haɗin gwiwa na Melfora tare da wasu magunguna, ana lura da halayen masu zuwa:
- Sakamakon warkewa na magungunan antianginal, cardiac glycosides, haɓakar hypoglycemic na haɓaka.
- Akwai haɗarin haɓaka tachycardia da hypotension lokacin ɗaukar Nifedipine, vasodilators, magungunan antihypertensive, alpha-adrenergic receptor blockers, Nitroglycerin.
Akwai haɗarin haɓakar tachycardia da hypotension tare da haɗin Nifedipine.
A ƙarshen batun, dole ne a kula da hankali.
Amfani da barasa
A lokacin da ake shan magani, ba a ba da shawarar a sha giya ba. Ethanol yana hana ayyukan tsarin juyayi na tsakiya, yana da sakamako na hepatotoxic kuma yana ƙaruwa da halayen mummunan sakamako. Ingan giya na Ethyl yana haifar da mutuwar ƙwayoyin hanta, wanda ke rage tasirin Melfor, kuma yana ƙaruwa da haɓakar haɓakar ƙwayar mai.
Analogs
| Take | Farashin, rub. | Ayyuka da bambance-bambance daga Melfora |
| Magnikor | 75 | Tushen maganin shine haɗakar acetylsalicylic acid da magnesium hydrochloride. Amfani da allunan don lura da ƙanƙanin isheemiya da na zuciya. |
| Harshen Tumbi | 274-448 | Saukad da allunan da ke cikin haɗin haɗuwa kan hauhawar jini, arrhythmia da sauran cututtukan zuciya. |
| Cordaflex | 76 | Akwai shi a cikin allunan da aka gaza. Abunda yake aiki shine nifedipine. Yana taimaka tare da cututtukan zuciya, ischemia na zuciya, hawan jini da hauhawar jini mai wahala mai yawa. |
| Amlipin | 340 | Hanyar aiwatar da miyagun ƙwayoyi ta dogara ne akan haɗarin lisinopril da amlodipine, waɗanda aka yi amfani dasu don magancewa da hana cututtukan zuciya. |
| Corvitol | 250 | Kwayar aiki mai aiki shine metoprolol, wanda ya zama dole don kula da angina pectoris, hyperthyroidism, bugun zuciya, kawar da ischemic sites da kuma daidaituwa na yawan zuciya. |
| Kudesan | 330 | Saukad da Allunan, da kayayyakin magungunan magani wanda aka bayyana saboda ubidecarenone. Ana amfani dasu don arrhythmias, don murmurewa bayan bugun zuciya, don magance cututtukan zuciya na zuciya. |
| Bisoprolol | 95-115 | Jiyya na angina pectoris, hauhawar jini da kuma rauni na zuciya. |
Magunguna kan bar sharuɗan
Ana sayar da maganin a cikin kantin magunguna daidai da rubutattun magunguna.
Farashi
Matsakaicin farashin maganin yana kai 500-560 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Wajibi ne don ɗaukar mafita da capsules na miyagun ƙwayoyi a zazzabi na + 15 ... + 25 ° C a wani wuri wanda ba zai iya dacewa da danshi da hasken rana ba.
Ranar karewa
Watanni 24.
Mai masana'anta
Ozone LLC, Rasha.
Nasiha
Marina Kutina, likitan zuciya, Rostov-on-Don
Na yi aiki tare da Melfor tsawon shekaru 6. Sanya don intramuscular, ciki da amfani da baka. Marasa lafiya suna ba da rahoton inganci a cikin kwanakin 10 na warkewa. Sakamakon warkewa shine ƙara ƙarfin hali, ƙaruwa da ƙarfi da kuma daidaituwa na tsarin zuciya. Ina wajabta magani na 500 MG. Ka'idojin yau da kullun na iya ƙaruwa a cikin jiyya na cututtukan zuciya da jijiyoyin zuciya, dystrophy na retinal, fundus, state-infarction state, myocardial dystrophy.Ba na ba da shawarar karɓar karuwa da ƙwaƙwalwar hankali.
Stepan Rogov, dan shekara 34, Irkutsk
Likita ya ba da allunan Melfor bayan rashin lafiyar Mildronate. Ina shan maganin har tsawon watanni tare da maimaita dogon karatun dangane da aikin akan juzu'i a arewa, wanda ke buƙatar juriya ta jiki. Akwai wasu matsalolin zuciya da gajiya daga yawan aiki. Lokacin ɗaukar capsules, gajiya yana raguwa, hare-haren angina ba su da yawa, yanayi yana inganta. Na bar magana mai inganci.
Julia Gerasimova, shekara 27, Lipetsk
Ina aiki a cikin kantin sayar da kaya har tsawon sa'o'i 12-14 a rana, wanda shine dalilin da yasa na gaji a jiki da tunani. Likita ya ba da maganin capsules na Melfora. Yanayin aiki - duk sati 2. Kayan aiki mai inganci wanda ke inganta sautin a jiki, yana inganta yanayi da maida hankali. Tasirin maganin yana jin kwanaki 2-3 bayan gudanarwa. An ɗauki capsules daidai bisa ga umarnin don guje wa sakamako masu illa.
