Magungunan Rosuvastin da Atorvastatin sune wakilai na hanawar jini. Toari da damar rage ƙwayar jini, suna da kaddarorin antioxidant kuma suna hana ci gaba da rarraba ƙwayoyin tumo. Kamfanin masana'antun magunguna na kasar Rasha daban-daban ne ya kera su kuma suna daga cikin kwayoyi na rubutattun kwayoyi.
Halayen rosuvastatin
Magungunan shine farin kwamfutar hannu biconvex wanda ke dauke da rosuvastatin abu mai aiki, a cikin abubuwan da aka tattara:
- 5 MG;
- 10 MG;
- 20 MG;
- 40 MG
Magungunan Rosuvastin da Atorvastatin ƙananan cholesterol, suna da kaddarorin antioxidant kuma suna haɓaka haɓakar ƙwayoyin tumo.
Ana sayar da Allunan a cikin katako. Mafi ƙarancin adadin a cikin kunshin shine 7 inji mai kwakwalwa., Matsakaicin shine 300 inji mai kwakwalwa.
A bioavailability na miyagun ƙwayoyi ya kusan 20%. Matsakaicin maida hankali a cikin jini ya kai 5 hours bayan gudanarwa. Cire rabin rayuwar shine awanni 19.
Yarinyar da aka ba da shawarar maganin shine 10 MG (ga marasa lafiya na tseren Mongoloid - 5 MG), ana ɗauka sau ɗaya a rana. Idan ya cancanta, ana iya haɓaka shi zuwa 20 MG sau ɗaya a rana, amma ba a baya ba bayan tsawon watanni na gudanarwa. Yin amfani da sashi na 40 MG na iya yiwuwa ne kawai a cikin nau'ikan cututtukan da ke tattare da cutar kuma gabaɗaya a ƙarƙashin kulawa na likita.
Alamar Atorvastatin
Abubuwan da ke aiki da miyagun ƙwayoyi abu ne guda ɗaya mai aiki, wanda za'a iya ƙunsar shi a cikin kwamfutar hannu a cikin abubuwan da ke tafe:
- 10 MG;
- 20 MG;
- 40 MG;
- 80 MG
Dogaro da mai ƙira, allunan na iya zama zagaye ko m, suna da rubutu a ɗayan ɓangarorin. Ana sayar da maganin a cikin kwali. Mafi ƙarancin allunan a cikin kunshin shine guda 10, matsakaicin shine guda 300.
Atorvastatin dole ne a ɗauka akan komai a ciki, saboda haɗuwa tare da abinci yana hana ɗaukar abu mai aiki.
Ana amfani da miyagun ƙwayoyi ta hanyar ƙananan bioavailability (12%). Matsakaicin maida hankali ana samun sa'o'i 1-2 bayan gudanarwa. Rabin rayuwar shine awa 13.
Sashi na miyagun ƙwayoyi ya dogara da farkon ƙwayar cholesterol kuma ya kamata a zaɓi shi daban-daban don kowane haƙuri. Yankin da aka bada shawarar farko shine 10 MG sau daya a rana. Matsakaicin da za'a iya yarda dashi a rana shine 80 MG. Dole ne a sha miyagun ƙwayoyi a kan komai a ciki. Haɗuwa tare da abinci yana haifar da ɗaukar abu mai aiki.
Kwatanta Miyagun Kwayoyi
Dukkanin magunguna biyu waɗanda ke ƙarƙashin kulawa suna cikin rukunin rukuni na roba. Idan aka kwatanta da sauran abubuwa na wannan aji, ana nuna su ta hanyar raguwa mai mahimmanci a matakin TG. Koyaya, kayan aikinsu ba iri ɗaya bane.
Kama
Wadannan kwayoyi suna da wannan manufar ta shan - ragewan cholesterol. Sakamakon magungunan su yana raguwa da hanawar rage ƙarfin HMG-CoA. Sakamakon waɗannan halayen shine raguwa a cikin ƙwayoyin cholesterol a cikin sel da kuma kunna catabolism na LDL cholesterol catabolism. Matsayin da maida hankali ya ragu sosai ya dogara da matakin maganin.
Positivearin tasirin tabbatacce daga shan Rosuvastatin ko Atorvastatin za su kasance:
- haɓaka aikin endothelium tare da lalatawar sa;
- normalization na rheological Properties na jini;
- haɓaka halin da jijiyoyin bugun jini da atheroma.
Alamu don amfanin su sune cututtukan da ke tafe:
- hypercholesterolemia na asali iri-iri, gami da homozygous familial hypercholesterolemia;
- nau'in hyperlipidemia IIa da IIb;
- Nau'in III na dysbetalipoproteinemia;
- endogenous hypertriglyceridemia (nau'in IV).
Bugu da kari, ana amfani da irin wadannan magungunan don maganin cutar sankara ta hanyar marassa lafiya tare da wasu dalilai da yawa don ci gaban cututtukan zuciya na zuciya, kamar:
- shekaru sama da 55;
- shan taba
- ciwon sukari mellitus;
- hauhawar jini
- low cholesterol (HDL) a cikin jini;
- jarabar kwayar halitta.
Hakanan an wajabta su ga waɗanda mutanen da suka rigaya suka kamu da cutar ischemia, don rage yiwuwar haɓakar angina pectoris, bugun zuciya ko bugun jini.
Magunguna suna da irin wannan maganin. Ba a ba da Rosuvastatin ko Atorvastatin ba:
- tare da cututtukan hanta a cikin aiki mai aiki;
- yayin daukar ciki da lactation;
- yara da matasa.
Tare da taka tsantsan, ya kamata a yi amfani da kwayoyi tare da:
- barasa;
- tsinkayar cutar sankarar mama;
- mai rauni na koda.
Abubuwan da ke tattare da halayen marasa kyau na jiki zuwa farwa tare da waɗannan magunguna sun yi kama. Lokacin da aka ɗauke su, ci gaban irin waɗannan sakamako masu illa kamar:
- rashin bacci da farin ciki, da sauran maganganu daga tsarin juyayi na tsakiya;
- dysfunctions na azanci, kamar asarar dandano ko tinnitus;
- ciwon kirji, arrhythmia, angina pectoris;
- anemia, rashin jini;
- mashako, ciwon huhu, asma, ciwan hanci;
- tashin zuciya da sauran abubuwan narkewa;
- amosanin gabbai, fashewar gout;
- kumburi
- haɓakar cututtukan urogenital;
- halayen cututtukan fata
- wani canji a kirga na gwajin jini;
- karin nauyi;
- girman nono;
- bayyanar cututtuka na rashin lafiyan.
Ana samun sakamako mafi ƙoshin warkewa bayan makonni 4 na jiyya tare da waɗannan kwayoyi.
Lokacin shan waɗannan magungunan, matan masu haihuwa dole ne suyi amfani da hanyoyin ingantattun maganin hana haihuwa.
Menene bambance-bambance
Duk da kamanceceniya, waɗannan kwayoyi sun kasance cikin tsararraki daban daban. Rosuvastatin sabon haɓaka ne wanda ke ba ka damar rage matsakaici da matsakaiciyar sashi na kayan aiki saboda haɓaka mafi girma.
Magungunan da ake tambaya suna da hanyoyi daban-daban na kawar:
- atorvastatin an cire shi daga jiki tare da bile a cikin hanyar metabolites wanda aka canza shi ta hanyar enzymes hanta;
- rosuvastatin - ba canzawa tare da feces.
Rosuvastatin abubuwa ne na hydrophilic, kuma Atorvastatin yana narkewa a cikin mai.
A cikin nau'in 2 na ciwon sukari na mellitus, an fi son a zaɓi rosuvastatin, tun da yake ba shi da tasirin gaske ga tasirin ƙwayoyin carbohydrates.
Wanne ne mafi aminci
Nazarin ya nuna cewa abin da ya haifar da tasirin sakamako iri ɗaya ne ga duka magunguna.
An lura cewa tare da nau'in ciwon sukari na 2, ya fi dacewa a zaɓi mutummutumi na hydrophilic, wanda ya haɗa da Rosuvastatin, tunda irin waɗannan abubuwan ba su da tasiri a kan yanayin ƙwayoyin carbohydrates.
Wanne ne mai rahusa
Farashin Rosuvastatin da Atorvastatin sun dogara da dalilai da yawa:
- yawan Allunan a kowace fakitin;
- masana'antun magunguna;
- manufofin farashin kantin magani;
- yankin sayan magani.
Shahararren kantin magani na kan layi yana bayar da siyar da Rosuvastatin a farashin da ke gaba:
- Allunan 30 na 10 MG da Izvarino Pharma suka samar - 545.7 rubles;
- Allunan 30 na 10 MG da aka ƙera ta hanyar Vertex - 349.3 rubles;
- Allunan 60 na MG 20, wanda Canonpharm Production LLC suka yi, - 830.5 rubles .;
- Allunan 90 na 20 MG da kamfanin ya samar "Arewa Star" - 1010.8 rubles.
Atorvastatin ana iya siyanta da kudin mai zuwa:
- Allunan 30 na 10 MG wanda kamfanin Arewa Star ya samar - 138 rubles;
- Allunan 30 na 10 MG wanda aka ƙera ta Ozone LLC - 65,4 rubles;
- Allunan 60 na 40 MG wanda kamfanin Arewa Star ya samar - 361.4 rubles;
- Allunan 90 na 20 MG na alamar Vertex - 799 rubles.
Daga farashin da aka ambata, ya bayyana sarai cewa Atorvastatin magani ne mai rahusa fiye da Rosuvastatin.
Wanne ya fi kyau - rosuvastatin ko atorvastatin?
Bayanai da aka samo kan kwatankwacin tasirin waɗannan magunguna sun nuna cewa rosuvastatin far yana da tasiri sosai akan rage yawan ƙwayoyin cholesterol. Bugu da kari, wannan magani ya kasance na mutum-mutumi ne na tsararraki 4 kuma yana ba da babban tasiri a matsayin maganin cutar sankara na jijiya.
Koyaya, zaɓin magani yakamata ya zama likita mai halartar kowane haƙuri, yin la'akari da halayen ɗabi'unsa, cututtukan haɗin gwiwa da kuma karfin kuɗi.
Shin ana iya maye gurbin rosuvastatin tare da atorvastatin?
Duk da cewa kwatancen abubuwanda aka tsara sun nuna cewa aikin Rosuvastatin da Atorvastatin ba abu daya bane, analog ne kuma ana musayar su. Koyaya, kafin motsawa daga wannan magani zuwa wani, yakamata ku nemi likita koyaushe, tunda magungunan magunguna sun sha bamban, sakamakon abin da waɗannan magungunan ke shafar ƙwayoyin hanta da kwakwalwa ta hanyoyi daban-daban, kuma suna da hanyoyi daban daban na shakatawa.
Likitoci suna bita
Grigory, dan shekara 46, Moscow: "Babban abin da mai haƙuri ke buƙatar sani lokacin shan irin waɗannan magunguna shi ne, manufarsu ba ta kawar da buƙatar bin umarnin da aka tsara ba. Da farko dai, koyaushe ina ba da shawarar Rosuvastatin, tunda an tabbatar da babban ingancinsa a asibiti. Idan mummunan halayen ya faru, Ina fassara su zuwa analogues" .
Valentina, 'yar shekara 34, Novosibirsk: "Na dauki shan wannan magungunan a matsayin kyakkyawan tsari na cututtukan zuciya da na jijiyoyin jini da kuma cututtukan cerebral arteriosclerosis.
Nazarin Marasa lafiya ga Rosuvastatin da Atorvastatin
Nikolai: shekara 52, Kazan: "Amfanin Atorvastatin kawai shine ƙaramar farashinta. A gare ni, gudanarwarsa ta kasance tare da ɗumbin raunin da ya faru: tashin zuciya da ciwon kai sun taɓarɓare a kai a kai. A lokaci guda, matakan cholesterol na haɓaka."
Svetlana, dan shekara 45, Murmansk: "A kan shawarar likita, na sauya daga ɗaukar Atorvastatin zuwa Rosuvastatin, saboda yawan maganin tashin zuciya. Ina iya cewa sabuwar ƙwayar ba ta haifar da irin wannan amsa ba, yayin da hakan kuma yana shafar matakan cholesterol."
