Gluconorm Plus yana nufin jami'ai masu yawa na cututtukan jini. Sakamakon kasancewar abubuwa da yawa masu aiki, za a iya samun sakamako mai kyau yayin aikin jiyya cikin sauri. Kayan aikin da aka yi la’akari da shi ya banbanta da kwatankwacin sunan guda (Gluconorm) a sashi mai girma. Haka kuma, magungunan biyu suna cikin nau'in farashin guda.
Sunan kasa da kasa mai zaman kansa
Metformin + Glibenclamide.
Gluconorm Plus yana nufin jami'ai masu yawa na cututtukan jini.
ATX
A10BD02.
Saki siffofin da abun da ke ciki
Ana iya samun magungunan kawai a cikin nau'ikan allunan. Ya ƙunshi sinadaran aiki: glibenclamide da metformin hydrochloride. Sashi a cikin kwamfutar hannu 1, bi da bi: 2.5 da 5 MG; 500 MG Bayan wannan haɗin abubuwa, abun da ke ciki ya ƙunshi ma'aunin kayan taimako na wannan nau'in sakin:
- microcrystalline cellulose;
- hyprolosis;
- croscarmellose sodium;
- magnesium stearate.
Allunan an rufe su da wani keɓaɓɓen shafi wanda ya rage ƙimar kwatancen abubuwa masu aiki. Sakamakon wannan, matakin mummunar tasiri akan ƙwayoyin mucous na ciki yana raguwa. Kuna iya siyan samfurin a cikin fakitin da ke kunshe da allunan 30.
Ana iya samun magungunan kawai a cikin nau'ikan allunan. Ya ƙunshi sinadaran aiki: glibenclamide da metformin hydrochloride.
Aikin magunguna
Tsarin Gluconorm Plus yana dogara ne akan tasirin abubuwan abubuwa daban daban. Kowane bangare yana aiki da ka'idodin kansa, amma a lokaci guda yana inganta tasirin ɗayan. Sakamakon tasiri mai rikitarwa, an rufe matakai daban-daban na kwayoyin halitta a cikin jiki, wanda ke ba da gudummawa ga rage saurin abubuwan glucose. Don haka, metformin mallakar bature ne. Wannan wakili ne wanda yake aiwatar da ayyuka daban-daban a lokaci guda:
- normalizes rabo daga insulin zuwa proinsulin da daure insulin to free, amma wannan tsari ba a kunna by Gluconorm, amma a sakamakon sauran halayen na jiki tsokani wannan magani.
- yana rage haɗuwa da glucose a cikin jini, wanda saboda hanawar haɗin metformin, a lokaci guda yana fara aiwatar da canji a cikin sel.
A ƙarshen banbanci na haɓakar gulukos, ƙwayar jijiyar nama zuwa insulin yana ƙaruwa. A lokaci guda, sakin kitse na kitse na ragewa. Kayan hada hada hada hada abubuwa ma da hankali. Yawan triglycerides, low yawa na lipoproteins, shima yana raguwa. A saboda wannan, ana rage yawan samuwar kitse na jiki, wanda kai tsaye ke shafar nauyin mutum. A kan tushen ingantaccen abinci mai gina jiki, ƙarancin kalori da kuma motsa jiki mai tsayi, ci gaban kiba yana tsayawa, wanda yake da mahimmanci musamman ga masu ciwon sukari.
Sakamakon kai tsaye na miyagun ƙwayoyi a kan rabo na nau'ikan insulin daban-daban saboda wasu halayen. Don haka, tare da maganin metformin, babu wani tasiri akan aikin samarda insulin, tunda wannan abu yana nuna kaddarorin hypoglycemic, yana kewaya sel. Duk da gaskiyar cewa wannan bangaren yana keta metabolism na cholesterol, yana rage yawan LDL, maganin baya rage abubuwan HDL. Godiya ga waɗannan halayen, nauyin ba kawai ya daina ƙaruwa ba, amma an lura da raguwarsa a ƙarƙashin wasu yanayi da yawa.
Wani abin mallaka na metformin shine ikon yin tasiri akan abubuwan da suka kirkiro na jini. Don haka, yayin jiyya tare da Gluconorm Plus, ƙirar fibrinolytic na jini an daidaita su. A sakamakon haka, rukunin jini da aka kafa. Wannan tsari ya samo asali ne daga toshe mai kunna plasminogen mai aiki.
Wani abin mallaka na metformin shine ikon yin tasiri akan abubuwan da suka kirkiro na jini.
Abubuwan da ke aiki na biyu (glibenclamide) suna cikin rukuni na abubuwan da suka samo asali na sulfonylurea. Hanyar wannan nau'in ita ce mafi inganci ga dukkanin magungunan cututtukan cututtukan cututtukan ƙwaƙwalwar ƙwayar cuta. Hanyar aikin glibenclamide yana dogara ne akan ikon yin tasiri akan ƙwayoyin beta na pancreatic. Lokacin yin hulɗa tare da masu karɓar su, rufewar potassium da tashoshi mai buɗe jiki.
Sakamakon waɗannan halayen shine kunnawar sakin insulin. Wannan shi ne saboda shigar alli a cikin sel. A mataki na ƙarshe, an lura da saki sosai na insulin a cikin jini, wanda ke taimakawa raguwar glucose. Ganin yadda ake amfani da wannan sinadari, yana da kyau a yi amfani da shi kawai wajen lura da marassa lafiya da ke dauke da kwayoyin beta na farji. In ba haka ba, an rage tasirin glibenclamide.
Pharmacokinetics
Ana amfani da Metformin cikin sauri. Matsayin da yake maida hankali a cikin jijiyoyin jini yana ƙaruwa zuwa ƙimar iyakarsa bayan 2 hours. Rashin ingancin abu abu ne na ɗan gajeren lokaci. Bayan awa 6, raunin plasma na metformin yana farawa, wanda shine sakamakon ƙarshen tsarin ɗaukar ƙwayar narkewa. Hakanan rabin rayuwar kayan yana raguwa. Tsawon lokacinta ya bambanta daga awa 1.5 zuwa 5.
Bugu da kari, metformin baya daure wa garkuwar plasma. Wannan abu yana da ikon tarawa cikin kyallen da ƙodan, hanta, gyada mai haɓaka. Renarancin kayan aiki na yara shine babban abin da ke ba da gudummawa ga tarawar metformin a cikin jiki, wanda ke haifar da karuwa a cikin wannan ɓangaren kuma ƙara haɓakarsa.
Renarancin aiki na ƙarancin ƙasa shine babban abin da ke ba da gudummawa ga tarawar metformin a cikin jiki, wanda ke haifar da karuwa a cikin inganci.
Glibenclamide yana tsawon lokaci - tsawon awanni 8-12. Babban ganiya yana aiki cikin awa 1-2. Wannan abun yana daure sosai da garkuwar jini. Tsarin canji na glibenclamide yana faruwa a cikin hanta, inda aka kirkiro mahadi 2 waɗanda ba su nuna ayyukan hypoglycemic ba.
Alamu don amfani
An ba da izinin amfani da maganin don maganin marasa lafiya da masu ciwon sukari na 2 a cikin wasu yanayi:
- rashin sakamako a cikin maganin da aka wajabta a baya na kiba, idan aka yi amfani da kowane daga cikin magungunan: Metformin ko Glibenclamide;
- gudanar da aikin sauyawa, samarda cewa matakin glucose a cikin jini yana da tsayayye kuma ana kulawa da shi sosai.
Contraindications
An lura da iyakoki da yawa waɗanda ba a amfani da kayan aikin tambaya ba:
- rashin haƙuri ga kowane ɓangare a cikin abun da ke ciki (aiki da aiki);
- nau'in ciwon sukari na 1;
- take hakkin carbohydrate metabolism a cikin ciwon sukari;
- matakin farko na cutarma;
- coma;
- babban raguwa a cikin glukoton jini;
- daban-daban pathological yanayin da taimako zuwa koda matsalar aiki na samfur, yana iya slowing sauka aiwatar shaye ruwa, cututtuka, bugu.
- duk wata cuta da ke tattare da rashi iskar oxygen, daga cikinsu akwai abin lura da karancin iskar ciki;
- lactic acidosis;
- mai yawan pathological jihohi, wanda su ne tushen for assigning insulin, a cikin wannan yanayin, da ƙarin ruri daga cikin abu na iya haifar da rikitarwa.
Yadda ake ɗaukar Gluconorm Plus?
Mitar shan allunan da yawan abubuwanda aka sanya aikin an tantance su akayi daban-daban. Halin mai haƙuri da ciwon sukari mellitus, kasancewar wasu cututtuka, da shekaru suna shafar zaɓin tsarin kulawa. Ana ɗaukar miyagun ƙwayoyi tare da abinci.
Tare da ciwon sukari
Fara farawa tare da karancin allurai. Tabletauki kwamfutar hannu 1 a rana. Haka kuma, maida hankali kan abubuwanda ke aiki na iya zama daban: 2.5 MG + 500 MG; 5 MG + 500 MG. A hankali, adadin metformin da glibenclamide yana ƙaruwa, amma ba fiye da 5 MG da 500 mg ba, bi da bi. Ana yin canji a cikin taro na kwayoyi kowane mako 2 har sai yanayin haƙuri ya daidaita.
Matsakaicin adadin maganin yau da kullun shine 4 Allunan, yayin allurai kayan aiki masu aiki a cikin 1 pc: 5 MG da 500 MG. Wani madadin shine allunan 6, amma adadin glibenclamide da metformin sune bi da bi: 2.5 mg, 500 MG. Abubuwan da aka nuna na maganin sun kasu kashi-kashi (2 ko 3), duka sun dogara da yawan allunan. Banda shi ne lokuta idan ana wajabta kwamfutar hannu 1 a kowace rana.
Sakamakon Gefen Gluconorm Plus
Akwai haɗarin nakasar gani saboda raguwar matakan glucose.
Gastrointestinal fili
Vomiting, tare da tashin zuciya, rashin cin abinci, tashin zuciya na ciki, dandano na karfe. Abunda ke faruwa na bayyanar cututtuka na jaundice, hepatitis ba shi da sauƙin lura, ayyukan hepatic transaminases yana ƙaruwa. Wannan sakamako ne na canje-canje a cikin hanta.
Vomiting tare da tashin zuciya shine ɗayan cututtukan da ke tattare da cutar.
Hematopoietic gabobin
Yawan rikice-rikice tare da canje-canje a cikin kayan da kaddarorin jini: thrombocytopenia, leukopenia, anemia, da sauransu.
Tsarin juyayi na tsakiya
Gajiya, ciwon kai da farin ciki, rauni gaba ɗaya, yanayin raunin hankali (da wuya).
Carbohydrate metabolism
Hypoglycemia, alamomin su ne tashin hankali, rikicewa, damuwa, hangen nesa, gari, rauni, da sauransu.
Daga gefen metabolism
Lactic acidosis
A ɓangaren fata
Akwai alamun rashin damuwa ga hasken rana.
Cutar Al'aura
Urticaria. Babban bayyanar cututtuka: kurji, itching, zazzabi. Erythema yana tasowa.
A miyagun ƙwayoyi na iya tsokanar da alerji a cikin yanayin itching da kurji.
Tasiri kan ikon sarrafa abubuwan inji
La'akari da cewa miyagun ƙwayoyi yana haifar da rushewar ido, wani lokacin yana ba da gudummawa ga ci gaban hypoglycemia, ana ba da shawarar yin taka tsantsan yayin kulawa tare da Gluconorm Plus yayin tuki.
Umarni na musamman
An tsara miyagun ƙwayoyi tare da taka tsantsan yayin da ya faru game da mummunan tasirin glandon thyroid, glandon gland, tare da zazzabi da ƙarancin ƙarancin abinci.
A lokacin jiyya, ana bada shawara don kula da matakin glucose koyaushe (a kan komai a ciki kuma bayan cin abinci).
Wajibi ne a sanar da likita game da cututtukan cututtukan cututtukan kwayoyin halittar dabbobi. A wannan yanayin, ana iya buƙatar canza canji a tsarin jigilar magani.
Gabanin tushen hanta da cututtukan koda, yawan haɗarin metformin a cikin jini yana ƙaruwa, wanda shine sakamakon jinkirin kawar da wannan abu. A sakamakon haka, lactic acidosis yana haɓaka.
Yi amfani da lokacin daukar ciki da lactation
Ba a sanya shi ba.
Dalilin Gluconorm Plus ga yara
Ba a yi amfani da shi ba, kawai maganin tsufa ne yarda.
Ba a amfani da magani don magance yara.
Yi amfani da tsufa
Ana ɗaukar miyagun ƙwayoyi tare da taka tsantsan, musamman idan mai haƙuri yana fuskantar matsanancin motsa jiki. A wannan yanayin, haɗarin lactic acidosis yana ƙaruwa.
Aikace-aikacen aiki mara kyau
Kada ayi kwayar magani don lalata lalacewar wannan sashin. Ana buƙatar sarrafa ikon ƙirƙirar ƙirƙirar Tare da raguwa mai mahimmanci a cikin hanyar jiyya an katse.
Amfani don aikin hanta mai rauni
Magungunan yana contraindicated cikin haɗarin gazawar hanta.
Yawan yawaitar Gluconorm Plus
Wannan kayan aiki yana da haɗari idan an yi amfani da shi azaman ajalin magani. A wannan yanayin, hypoglycemia yana haɓaka, tunda ana aiki hanyoyin saki insulin. A lokaci guda, ana amfani da glyconeogenesis da amfani da glucose sosai. Sakamakon haka, tare da karuwa a cikin kashi na Gluconorm Plus, rikice-rikice suna haɓaka.
Farfadowar ya shafi daidaituwar abincin. Mai haƙuri dole ne ya ɗauki kashi na carbohydrates a kowane nau'i. Idan mummunar cuta ta taso, tare da wari, ana gudanar da magani ne a asibiti: ana gudanar da maganin dextrose a cikin jijiya.
Lokacin da kashi na Gluconorm Plus ya karu, lactic acidosis na iya haɓaka. Wannan yanayin na ilimin likita yana buƙatar magani a asibiti. Haka kuma, ana amfani da lactate da metformin yadda ya kamata daga jiki ta hanyar amfani da shi. Don cire glibenclamide, wannan hanyar ba ta dace ba, saboda wannan abun yana daure sosai da garkuwar jini.
Magungunan yana contraindicated cikin haɗarin gazawar hanta.
Yin hulɗa tare da wasu kwayoyi
Amincewar amfani da Gluconorm Plus da Miconazole suna ba da gudummawa ga haɓakar haɓakar jini.
Ba a amfani da samfuran da ke ɗauke da Iodine tare da maganin a cikin tambaya. Wannan yakamata ayi la'akari dashi yayin gudanar da sahihancin da ake buƙatar yin amfani da haɓakar bambanci tare da abubuwan da ke iodine.
Phenylbutazone yana haɓaka aikin da miyagun ƙwayoyi ke tambaya - yana ba da gudummawa ga ƙarin raguwa a cikin matakan glucose.
Besontan tsokani ƙara yawan tasirin mai guba akan hanta.
Adadin kwayoyi da abubuwa waɗanda ke buƙatar taka tsantsan:
- Chlorpromazine;
- GCS;
- beta-adrenergic agonists da adrenergic blockers;
- kamuwa da cuta;
- Danazole;
- ACE masu hanawa.
Amfani da barasa
Ba za a iya haɗa giya da ke da giya tare da Gluconorm Plus ba.
Analogs
Waɗanda suke cancanta:
- Glibomet;
- Janumet;
- Metglib;
- Glucophage da sauransu.
Magunguna kan bar sharuɗan
Magunguna magani ne.
Zan iya saya ba tare da takardar sayan magani ba?
A'a.
Farashin Gluconorm da
Matsakaicin farashin: 160-180 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Yaran da aka bayar da shawarar zazzabi: har zuwa + 25 ° С.
Ranar karewa
Ana adana kaddarorin magungunan na shekaru 2 daga ranar da aka sake su.
Mai masana'anta
Pharmstandard-Tomskkhimfarm OJSC, Rasha.
A cikin tsufa, ana ɗaukar miyagun ƙwayoyi tare da taka tsantsan, musamman idan mai haƙuri yana fuskantar matsanancin motsa jiki.
Nazarin Gluconorm Plus
Likitoci
Valiev A.A., endocrinologist, dan shekara 45, Vladivostok
Ingantaccen magani. Sakamakon da ake so na ilmin likita ana iya samunsa nan da nan, amma irin waɗannan alamu suna da alaƙa da haɗarin rikitarwa. Ragewa da saurin sukari a cikin jini yana haifar da hypoglycemia, saboda haka zaku iya ɗaukar magani kawai bayan tuntuɓar likita.
Shuvalov E. G., therapist, 39 years old, Pskov
Wannan maganin yana aiki daidai. Ana iya ɗaukar shi tare da nau'in ciwon sukari na 2. Na lura adadi mai yawa na sakamako masu illa, contraindications. Na yi la'akari da fa'ida ta zama farashi mai araha, wanda yake da mahimmanci, saboda sau da yawa marasa lafiya dole ne su ɗauki waɗannan kwayoyin.
Marasa lafiya
Veronika, 28 years old, Yaroslavl
Kwanan nan na gano ciwon sukari. Yayinda nake koyon zama tare da shi, Ina buƙatar abinci da kula da glucose na lokaci-lokaci. Na kuma dauki wannan magani, yana taimakawa da sauri, kuma wannan ƙari ne, saboda mafi girman tsorona shine rashin daidaituwa ga asalin raguwar matakan glucose.
Anna, shekara 44, Samara
Magungunan ba su dace ba. Bayar da sakamako masu illa. Ciwon kai, tashin zuciya, raunin gani - Na sami waɗannan alamun a kaina. Da farko likitan ya yarda cewa batun yana cikin sashi, amma har ma mafi kyawun tsarin kulawa da ladabi bai gyara matsalar ba.
