An wajabta Atorvastatin ko Simvastatin don runtse cholesterol da haɓaka tafiyar matakai na rayuwa. An yi amfani da magunguna duka biyun a cikin aikin likita, sabili da haka, sun tabbatar da kansu duka don magani da kuma rigakafin cututtukan zuciya.
Alamar Atorvastatin
Atorvastatin yana nufin magungunan rage yawan lipid daga rukuni na statins. Atorvastatin alli trihydrate (10.84 mg) abu ne mai aiki wanda ya shiga cikin kwayar cholesterol. Wannan kayan yana taimakawa rage yawan lipoproteins mai ƙarancin ƙarfi (LDL) da babban yawa (HDL), don haka hana ƙirƙirar filayen cholesterol.
An wajabta Atorvastatin ko Simvastatin don runtse cholesterol da haɓaka tafiyar matakai na rayuwa.
Bayan shigar ciki, kwamfutar hannu ta shiga cikin karamin hanjin ta, inda nan take ta shiga tsarin jini ta jikin bangon ta. A bioavailability na aiki mai aiki shine 60%. Enzymes na hepatic yana aiki da kayan magani, kuma an cire ragowar daga jiki da feces, fitsari da gumi.
Babban cholesterol a cikin atherosclerosis, kasancewar filaye a cikin manya da kanana sune manyan alamomin amfani da Atorvastatin. Haka kuma yana da kyau a rubuto magani don rigakafin wadannan cututtukan:
- nau'in ciwon sukari guda 2;
- bugun zuciya;
- bugun jini;
- hauhawar jini
- angina pectoris;
- ischemia na zuciya.
Atorvastatin yana nufin magungunan rage yawan lipid daga rukuni na statins.
Atorvastatin yana da ikon tarawa a cikin jiki tare da amfani da tsawan lokaci da wasu cututtukan cuta, alal misali, idan aikin hanta ko koda ke da rauni. A wannan yanayin, ana lura da sakamako mai guba na miyagun ƙwayoyi. Mai haƙuri na iya yin gunaguni da zazzabi, ciwon kai, rauni na gaba ɗaya, da saurin aiki. Idan ka yi watsi da duk waɗannan alamun, to, yiwuwar gubar gaba ɗaya ta jiki tana da yawa.
Halayen simvastatin
Maganin Simvastatin shima yana cikin rukunin gumakan. Abubuwan da ke aiki da miyagun ƙwayoyi shine simvastatin. Wadanda suka ware sun hada da:
- titanium dioxide;
- lactose;
- povidone;
- citric acid;
- acid na ascorbic;
- magnesium stearate, da sauransu.
Simvastatin yana da babban matakin sha. Matsakaicin mafi yawan abubuwan aiki a cikin jini ana samun sa'o'i 1-1.5 bayan gudanarwa. Bayan awa 12, wannan matakin ya ragu da kashi 90%. Babban hanyar shakatawa shine ta hanjin ciki, ta hanjin kodan, kashi 10-15% na kayan aiki masu aiki an kebe su.
Babban dalilin maganin shine rage cholesterol a cikin cututtukan zuciya. An wajabta maganin a irin waɗannan lokuta:
- babban haɗarin bunkasa atherosclerosis;
- na farko hypercholesterolemia (nau'in II a da II b);
- hypercholesterolemia da hauhawar jini;
- don rigakafin infarction na zuciya daga zuciya, bugun jini, harin ischemic, atherosclerosis na tasoshin zuciya.
Babban manufar yin amfani da Simvastatin ita ce rage ƙananan cholesterol a cikin cututtukan zuciya.
Kwatanta Atorvastatin da Simvastatin
Bayar da magani kuma zaɓi hanyar tsarawa ya kamata ya zama gwani kawai wanda zaiyi la'akari da hanyar cutar ba kawai, amma halayen mutum na jiki.
Kama
Dukansu magungunan suna da amfani sosai a cikin aikin zuciya don jiyya da kariya daga cututtukan zuciya da na jijiyoyin jini.
Dukansu Atorvastatin da Simvastatin sune magunguna masu tasiri kuma suna da manufa guda ɗaya - rage ƙwaƙwalwar jini.
Hakanan sun haɗu da waɗannan abubuwan:
- Magungunan suna da kayan aiki daban-daban, amma akwai lactose a cikin duka. Don haka, ya kamata a umurce su da hankali tare da fahimtar wannan bangaren na taimako.
- Sakamakon sakamako a cikin nau'i na tsananin zuciya shine halayyar magunguna biyu. A saboda wannan dalili, yayin lokacin kulawa, ya kamata ku ƙi fitar da mota kuma kuyi aiki tare da madaidaitan hanyoyin.
- An ba da magani ga magunguna tare da magunguna masu rage kiba, domin myopathy na iya haɓaka. Idan, a kan asalin aikin jiyya tare da Atorvastatin ko Simvastatin, zazzabi ya tashi kuma jin zafi ya bayyana, to ya kamata a watsar da magunguna, yana maye gurbinsu da analogues.
- Ciki da juna biyu wata sabuwa ce. Mata a lokacin jiyya dole ne su yi amfani da maganin hana haihuwa.
- Tare da yin amfani da dogon lokaci da yawan wuce gona da iri, da yiwuwar tasirin sakamako yana da girma. A irin waɗannan halayen, kodan da hanta suna wahala mafi yawa. Sabili da haka, an hana shi sosai a wuce adadin da likitan ya umarta.
Mene ne bambanci
Babban bambanci shine cewa abun da aka shirya na shirye-shiryen ba shine abu mai aiki ba. Don haka, atorvastatin yana nufin siffofin roba, waɗanda suke da tasirin warkewa na daɗewa. Simvastatin shine statin na halitta tare da sakamako na ɗan gajeren lokaci.
Abunda ke aiki na Atorvastatin yafi karfi, sabili da haka, wannan magungunan yana da ƙarin contraindications. Wadannan sun hada da:
- ciki da lactation;
- shekaru har zuwa shekaru 10;
- na kullum mai shan giya;
- karuwar adadin transaminases a cikin jini;
- rashin lafiyan halayen lactose;
- cututtuka a cikin babban mataki.
Ba a ba da shawarar Simvastatin don amfani ba a cikin halayen masu zuwa:
- hypersensitivity ga abubuwan da ke cikin miyagun ƙwayoyi;
- cutar hanta
- karamin shekaru;
- ciki da lactation;
- lalacewar tsoka.
Atorvastatin ba a son amfani da shi lokaci ɗaya tare da masu hana ƙwayoyin cuta da magungunan ƙwayoyin cuta. Ba za a iya haɗa Simvastatin tare da masu hana HIV da magungunan kashe ƙwari ba. Kada ku ci ruwan innabi ko ku sha ruwan innabi lokacin da kuke kula da allunan. wannan hade yana iya wucewa da maida hankali kan abubuwanda suke aiki a cikin jini.
Sakamakon sakamako masu zuwa na iya faruwa yayin ɗaukar Simvastatin:
- matsalolin narkewa;
- rashin bacci
- ciwon kai
- take hakkin dandano da hangen nesa (da wuya);
- ƙaruwar ESR, raguwa a cikin platelet da ƙwayoyin jini.
Yayin aikin jiyya tare da Atorvastatin, marasa lafiya na iya fuskantar tinnitus, matsalolin ƙwaƙwalwar ajiya, da kuma jin gajiya kullun.
A kan asalin ɗaukar Simvastatin, ciwon kai na iya faruwa.
Ana nuna alamar hemodialysis a cikin lokuta na overdose na simvastatin. Irin wannan hanyar ba za ta zama da amfani ba a cikin irin wannan yanayin tare da Atorvastatin.
Wanne ne mai rahusa
Farashin magunguna ya dogara da ƙasar kerawa da sashi.
Ana yin Simvastatin a cikin ƙasashe da yawa, ciki har da Rasha, Faransa, Serbia, Hungary, da Czech Republic. Kudin kunshin na allunan 30 na allunan 20 zai zama 50-100 rubles. Farashin shirya magani (guda 20. Don 20 MG) wanda aka samar a cikin Czech Republic kusan 230-270 rubles.
Atorvastatin na kayan Rasha ana iya siyan su a cikin magunguna a wannan farashin:
- 110 rub - 30 inji mai kwakwalwa. 10 MG kowane;
- 190 rub - 30 inji mai kwakwalwa. 20 MG kowane;
- 610 rub - 90 inji mai kwakwalwa. 20 MG kowane.
Wanne ya fi kyau - atorvastatin ko simvastatin
Likita mai halarta ne kawai zai iya ba da labarin wane magani ne mafi kyau bayan bincika mai haƙuri, amma akwai wasu mahimman abubuwa na magungunan:
- Za'a iya samun sakamako mai inganci mai sauri tare da Atorvastatin, kamar yadda ya ƙunshi abu mai aiki tare da tasiri mai ƙarfi.
- Simvastatin yana haifar da ƙananan sakamako masu illa, wanda shine amfanin wannan magani. Lokacin da aka yi amfani da shi daidai, abubuwan guba a kusan basa tarawa cikin jiki.
- Sakamakon bincike na asibiti na magungunan, an tabbatar da cewa Simvastatin yana rage cholesterol mai cutarwa da 25%, da Atorvastatin - da kashi 50%.
Don haka, don tsawanta na jiyya game da cututtukan cututtukan ƙwayar cuta, ya kamata a zaɓi Atorvastatin, kuma don rigakafin cututtukan jijiyoyin jiki, ya fi kyau amfani da Simvastatin.
Neman Masu haƙuri
Olga, 37 years old, Veliky Novgorod
Bayan bugun zuciya, an wajabtawa Simvastatin don rage cholesterol. Jiyya yana tsawan watanni 4 kuma a wannan lokacin babu sakamako masu illa. Ba za a iya musantawa da miyagun ƙwayoyi ba ne farashin, raɓa - ƙarancin inganci. Binciken da aka maimaita shine ya nuna cewa matakin mummunan kwayar cholesterol ya ragu kadan. Baba ya damu, saboda yana da babban fata na magani. Na yi imani cewa simvastatin yana taimakawa a cikin maganganun milder, kuma ba a cikin manyan ci gaba ba. Yanzu ana ba mu magani tare da wani magani.
Mariya Vasilievna, 57 years old, Murmansk
A gwaji na gaba, likita ya ce kololulerol ya ɗan ƙaru kuma ya ba da shawarar ɗaukar gumaka. Na ɗauki Simvastatin, na bi abinci kuma na bi motsa jiki mara ƙima. Bayan watanni 2 na wuce bincike na biyu, wanda dukkanin alamu suka koma al'ada. Ban yi nadamar cewa na sha maganin ba, kodayake mutane da yawa sun yi gargaɗi game da lahani da rashin amfani a cikin jinina. Ina mai farin cikin cewa an sami sakamako. Ina bayar da shawarar shi!
Galina, shekara 50, Moscow
Na ji tsoro lokacin da na ji daga likita cewa akwai kwayar cholesterol fiye da 8. Ina tunanin cewa magani zai kasance mai tsawo da wahala. Atorvastatin aka wajabta. Ban sanya wani takamaiman bege game da maganin ba, amma a banza. Bayan watanni 2 na magani, cholesterol ya ragu zuwa 6. Ban yi tsammanin maganin zai taimaka ba. Ina so in lura cewa na sha sosai a kan shawarar likita kuma babu wasu sakamako masu illa.
Dukansu magungunan suna da amfani sosai a cikin aikin zuciya don jiyya da kariya daga cututtukan zuciya da na jijiyoyin jini.
Likitoci sun bita kan Atorvastatin da Simvastatin
Egor Alexandrovich, dan shekara 44, Moscow
Da kyar na iya rubuta Simvastatin, saboda Na dauke shi magani ne na karni na karshe. Yanzu akwai wasu gumakan zamani waɗanda suka fi tasiri da aminci. Misali, atorvastatin. Wannan maganin ba kawai zai iya rage matakin mummunan cholesterol ba, amma yana rage haɗarin bugun zuciya da bugun jini. M fitarwa mai dacewa.
Lyubov Alekseevna, mai shekara 50, Khabarovsk
A cikin aikin likita, Ina ƙoƙari don tsara Atorvastatin ga marasa lafiya idan babu contraindications. Na yi imani cewa wannan magani yana aiki a hankali, ba tare da rushe aikin gabobin ciki da tsarin jikin mutum ba. Da wuya marasa lafiya su koka da tasirin sakamako, wanda yake mahimmanci. Bayan duk, yawancin masu fensho suna zuwa da irin wannan matsala, waɗanda suka riga sun sami cututtuka na kullum.
