Tasirin miyagun ƙwayoyi Ryzodeg a cikin ciwon sukari

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Rysodeg FlexTouch magani ne mai ƙoshin lafiya wanda ke da tasirin warkewa a cikin jiyya na nau'in 1 ko nau'in ciwon sukari na 2. Yin amfani da insulin biphasic yana rage bukatar yin allura akai-akai.

Sunan kasa da kasa mai zaman kansa

Insulin dagasari + Insulin kamar yadda yake shi (Insulin degcin + Insulin kamar yadda yake so).

Rysodeg FlexTouch magani ne mai ƙoshin lafiya wanda ke da tasirin warkewa a cikin jiyya na nau'in 1 ko nau'in ciwon sukari na 2.

ATX

A10AD06.

Saki siffofin da abun da ke ciki

Magani don allurar subcutaneous. Ya ƙunshi insulin degludec da insulin cikin kashi 70:30. 1 ml ya ƙunshi IU 100 na mafita. Ingredientsarin sinadaran:

  • glycerol;
  • abubuwan mamaki;
  • metacresol;
  • zinc acetate;
  • sodium chloride;
  • hydrochloric acid da sodium hydroxide don daidaita ma'aunin acid;
  • ruwa don yin allura.

Don haka, an sami pH na 7.4.

A cikin alkalami na 1, an cika 3 ml na bayani. Rukunin 1 na miyagun ƙwayoyi shine 25.6 μg na insulin degludec da 10.5 μg na insulin aspart.

Aikin magunguna

A miyagun ƙwayoyi ya ƙunshi sauƙin digirinble anael na insulin-mutum na tsawon-lokaci (degludec) da sauri (kewayawa). Ana samo sinadarin ta amfani da hanyoyin ƙirar halitta ta amfani da nau'ikan ƙananan ƙwayoyin saccharomycetes.

Wadannan nau'ikan insulin sun danganta ga masu karbar insulin na halitta da aka samar a jikin mutum kuma suna bayar da tasirin magani. Ana samar da sakamako na rage yawan sukari ta hanyar inganta tsarin dauri na glucose da kuma rage girman samuwar wannan kwayar halittar a cikin hanta hanta.

Magungunan suna ɗaure wa masu karɓar insulin na halitta da aka samar a jikin mutum kuma suna da tasirin magani.

Deglodec bayan p / a cikin siffofin da za'a iya kimanta mahaɗan a cikin ɗakunan ƙwayar ƙwayar cuta, daga inda ya shimfiɗa a hankali zuwa jini. Wannan yana bayyana bayanin martaba na insulin da kuma aikin da yayi. Aspart fara aiki da sauri.

Adadin jimlar na 1 ya fi awowi 24.

Pharmacokinetics

Bayan allurar subcutaneous, an kafa tsayayyun degludec multihexamers. Saboda wannan, an ƙirƙiri wani abu mai ɓoyayyen kayan daga ciki, yana samar da jinkirin kwanciyar hankali zuwa cikin jini.

Aspart yana cikin da sauri: ana gano bayanan an riga an gano bayanan 15 mintuna bayan allura a ƙarƙashin fata.

An kusan rarraba magungunan gaba daya a cikin plasma. Rushewar ta iri ɗaya ce da ta insulin ɗan adam, kuma kayan aikinta ba su da aikin magani.

Cire rabin rayuwar ba ya dogara da yawan magunguna kuma ya kusan awanni 25.

Alamu don amfani

Ana amfani dashi don kula da mutane da nau'in 1 da nau'in ciwon sukari na 2.

Ana amfani da Rysodeg don kula da mutane da nau'in 1 da nau'in ciwon sukari na 2.
An yiwa Ryzodeg contraindicated lokacin ciyar da jariri tare da madara.
An ɗaukar cutar Ryzodeg a cikin yara 'yan ƙasa da shekara 18.

Contraindications

An sanya shi cikin irin waɗannan lamura:

  • rashin hankali ga abubuwan da ke ciki;
  • gestation;
  • shayarwa;
  • shekaru zuwa shekaru 18.

Yadda ake ɗaukar Ryzodeg?

Ana gudanar da maganin a karkashin subcutaneally 1 ko sau 2 a rana kafin abinci. Wani lokaci ana yarda da mai ciwon sukari don ƙayyade lokacin gudanar da maganin. Ga mutanen da ke da nau'in ciwon sukari na 2, ana ba da maganin a matsayin wani ɓangaren monotherapy, kuma a hade tare da magungunan hypoglycemic da aka yi amfani da su a cikin gida.

Don haɓaka matakan sukari na jini, ana nuna daidaituwa na sashi yayin ƙaruwa ta jiki, canjin abinci.

Matsayi na farko don nau'in ciwon sukari na 2 shine raka'a 10. A nan gaba, an zaɓi yin la'akari da yanayin mai haƙuri. Tare da ciwon sukari mai dogaro da insulin, kashi na farko ya kai 70% na yawan buƙata.

Don haɓaka matakan sukari na jini, ana nuna daidaituwa na sashi yayin ƙaruwa ta jiki, canjin abinci.
Ga mutanen da ke da nau'in ciwon sukari na 2, ana bayar da maganin a matsayin wani ɓangare na monotherapy, kuma a hade tare da magungunan hypoglycemic.
Marasa lafiya suna buƙatar canza yanayin kullun allurar rigakafin miyagun ƙwayoyi.

An gabatar dashi cikin cinya, cinya, hadin gwiwa. Marasa lafiya suna buƙatar canza yanayin kullun allurar rigakafin miyagun ƙwayoyi.

Har yaushe za a ɗauka?

Tsawon lokacin izinin likita ne yake ƙaddara.

Sharuɗɗa don amfani da alkalami na syringe

An tsara katako don amfani da allura har tsawon mm 8 mm. Alƙalin sirinji na amfanin mutum ne kawai. Yadda ake amfani da shi:

  1. Tabbatar cewa katangar ta ƙunshi insulin kuma ba ta lalacewa.
  2. Cire hula kuma saka allurar da ake zubar dashi.
  3. Saita kashi akan lakabin ta amfani da mai zaɓa.
  4. Latsa farawa sai ƙaramin digo na insulin ya bayyana a ƙarshen.
  5. Yi allura. Matashin bayan yakamata ya kasance a sifili.
  6. Cire allurar bayan dakika 10.

Sakamakon sakamako na Rysodegum

Sau da yawa hypoglycemia. Yana haɓaka sabili da ƙayyadadden zaɓi da aka zaɓa, canji a abinci.

Sakamakon sakamako na miyagun ƙwayoyi shine halayen rashin lafiyan mutum a cikin hanyar kumburi da harshe da lebe.
Wani lokaci allurar subcutaneous tana haifar da ci gaban lipodystrophy.
Sakamakon sakamako na miyagun ƙwayoyi shine yiwuwar bayyanar urticaria.
Sau da yawa wani sakamako na gefe na shan miyagun ƙwayoyi yana ƙaruwa bugun bugun zuciya.
Sakamakon sakamako na miyagun ƙwayoyi shine halayen rashin lafiyan mutum a cikin nau'in nauyi a cikin ciki.
Sakamakon sakamako na miyagun ƙwayoyi shine halayen rashin lafiyan mutum a cikin nau'in zawo.

A ɓangaren fata

Wani lokaci allurar subcutaneous tana haifar da ci gaban lipodystrophy. Zai yuwu a iya magance shi koyaushe idan kuna canza shafin allurar. Wani lokacin hematoma, basur, zazzabi, kumburi, kumburi, jan launi, haushi da matse fata yana fitowa a wurin allurar. Suna wucewa da sauri ba tare da magani ba.

Daga tsarin rigakafi

Hannun jari na iya bayyana.

Daga gefen metabolism

Hypoglycemia yana faruwa idan kashi na insulin ya wuce yadda ake buƙata. Raguwar raguwar glucose yana haifar da asarar hankali, rikicewar jiki da lalatawar kwakwalwa. Bayyanar cututtuka na wannan yanayin suna haɓaka cikin hanzari: ƙoshin ɗumi, rauni, tashin hankali, bushewa, gajiya, amai, yunwar, zawo. Sau da yawa, bugun zuciya yana kara karfi, kuma hangen nesa yana rauni.

Cutar Al'aura

Kumburi da harshe, lebe, nauyi a cikin ciki, fata mai ƙaiƙayi, zawo. Wadannan halayen na ɗan lokaci ne kuma, tare da ci gaba da magani, a hankali sun ɓace.

Tasiri kan ikon sarrafa abubuwan inji

Sakamakon cututtukan hypoglycemia, maida hankali na iya lalacewa a cikin marasa lafiya. Sabili da haka, a haɗarin rage glucose, ana bada shawarar guji tuki motocin ko injuna.

Sabili da haka, a haɗarin rage glucose, ana bada shawarar guji tuki motocin ko injuna.

Umarni na musamman

Yayin aikin jiyya, masu gabatar da yanayin yanayin rashin haila na iya haɓaka. A kan lokaci, sai su wuce. Cututtukan kamuwa da cuta sun kara bukatar insulin.

Insuarancin kuzari na Ryzodegum yana haifar da ci gaban bayyanar cututtuka na cututtukan hawan jini. Alamomin ta sun bayyana a hankali.

Dysfunction na adrenal gland shine yake, glandon thyroid da pituitary gland shine yake buƙatar canji a cikin maganin.

Lokacin canja wurin mai ciwon sukari zuwa allurar Ryzodegum Penfill, ana sanya kashi ɗaya kamar insulin na baya. Idan mai haƙuri ya yi amfani da tsarin kula da maganin basal-bolus, to, an ƙaddara matakin gwargwadon buƙatun mutum.

Idan aka rasa allura ta gaba, to mutumin zai iya shigar da maganin da aka tsara a ranar. Kada ku sarrafa kashi biyu, musamman a cikin jijiya, saboda yana haifar da ƙwanƙwasa jini.

An hana shi shiga intramuscularly, saboda ɗaukar insulin canje-canje. Karka yi amfani da wannan insulin a cikin matattarar insulin.

Yi amfani da tsufa

A cikin cututtukan concomitant pathologies, ana buƙatar daidaita sashi.

A cikin tsufa, tare da cututtukan concomitant pathologies, ana buƙatar daidaita sashi.

Aiki yara

Ba a yi nazarin tasirin yara ba. Sabili da haka, masana ilimin likitanci ba da shawarar gudanar da wannan insulin ga yara 'yan ƙasa da shekara 18 ba.

Yi amfani da lokacin daukar ciki da lactation

Kada a wajabta wa mata yayin haihuwa da shayarwa. Wannan ya faru ne sakamakon karancin karatun asibiti dangane da amincin miyagun ƙwayoyi a cikin waɗannan lokutan.

Aikace-aikacen aiki mara kyau

A cikin cutar koda mai rauni, ana buƙatar daidaita sashi.

Amfani don aikin hanta mai rauni

Zai iya buƙatar rage adadin kudaden.

Adadin yawa na Ryzodegum

Tare da kara allurai, hypoglycemia na faruwa. Ainihin adadin lokacin da za'a iya faruwa ba.

Ana cire nau'i mai laushi da kansa: ya isa a yi amfani da ɗan adadin mai zaki. An shawarci marasa lafiya suyi sukari tare da su. Idan mutum bai san komai ba, an wajabta masa glucagon a cikin tsoka ko a ƙarƙashin fata. Na / O ne kawai ke gudanar da aikin kula da lafiya. Ana gabatar da Glucagon kafin a fitar da mutum daga yanayin rashin sani.

Yin hulɗa tare da wasu kwayoyi

Rage bukatar insulin hade da:

  • magunguna na baki don magance hyperglycemia;
  • agonists na GLP-1;
  • MAO da masu hana ACE;
  • beta-blockers;
  • shirye-shiryen salicylic acid;
  • anabolics;
  • wakilan sulfonamide.

Lokacin hulɗa tare da anabolics, buƙatar insulin yana raguwa.

Needara buƙata:

  • Yayi kyau
  • magunguna don haɓaka fitowar fitsari;
  • corticosteroids;
  • cututtukan ƙwayar thyroid na analogues;
  • Harkar ciki;
  • Danazole

Haramun ne a kara wannan magani ga mafita don shigar da ciki.

Amfani da barasa

Ethanol yana haɓaka tasirin hypoglycemic.

Analogs

Misalan wannan maganin sune:

  • Haskakawa
  • Tujeo;
  • Levemir.
Tallace-tallacen Films na Ryzodeg Darwin © 2015

Magunguna kan bar sharuɗan

An sake shi ta hanyar takardar sayan magani.

Zan iya saya ba tare da takardar sayan magani ba?

A'a.

Farashi

Kudin 5 alkalami da za'a iya zubar dasu kusan 8150 rubles.

Yanayin ajiya na miyagun ƙwayoyi

Adana alƙalumman da aka rufe da katako a cikin firiji a zazzabi na + 2ºС.

Ranar karewa

Watanni 30

Mai masana'anta

Novo Nordisk A / S Novo Alle, DK-2880 Baggswerd, Denmark.

Levemir shine analog na Ryzodegum.
Tujeo kwatanci ne na Ryzodeg.
Glargin alama ce ta Ryzodegum.

Nasiha

Marina, shekara 25, Moscow: "Wannan alkalami ne mai dacewa don shigar da insulin a ƙarƙashin fata. Ban taɓa kuskure da kashi ba. A yanzu dai allurar ta zama mara zafi. Babu wani yanayi na rashin ƙarfin halin jini. Ina sarrafa cutar da abinci, Na sarrafa zuwa 5 mmol."

Igor, ɗan shekara 50, St. Petersburg: "Wannan ƙwayar tana taimakawa wajen sarrafa sukari na jini fiye da waɗansu. Babban fa'idarsa shine ana iya bayar da allura sau ɗaya a rana. Godiya ga alkalami mai dacewa, allura ta kusan zama mara wahala."

Irina, 'yar shekaru 45, Kolomna: "Magungunan na taimaka wa barin abubuwan glucose kusa da na al'ada fiye da na sauran. Abubuwan da ke tattare da tunaninsu na ba ku damar gujewa allura mai yawa yayin rana. Yanayin lafiya yana da gamsarwa, cututtukan cututtukan cututtukan jini sun tsaya."

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