Bayyanar cututtuka da lura da insulinomas na pancreatic

Insulinoma da ke faruwa a cikin jijiyoyin jiki ana ɗauka cewa shine ƙwanƙwaran hormonal mai aiki. A mafi yawan halaye, tsari ne maras kyau kuma zai iya haifar da cutar kansar kan jiki kawai a cikin 15%.

Insulinoma yana da alamomi daban-daban waɗanda suka dogara da matakin kariya na jiki, halayen mutum, tasirin abubuwan waje ko na ciki. Cutar tana da wahalar kamuwa da cuta, don haka marassa lafiya su yi watsi da bayyanar, kuma har ma da alamun farko ya kamata su nemi likita.

Sanadin da pathogenesis

Ba a san ainihin musabbabin abubuwan insulinomas ba. Kawai haɗin wannan wannan neoplasm tare da adenomatosis, wanda ke a matsayin cutar ƙwayar cuta mai saurin cutar kuma yana ba da gudummawa ga haɓakar ƙwayar jijiyoyin ƙwayoyi.

Koda yake, akwai wasu zatorori game da asalin insulinomas, wadanda basu sami tabbacin kimiyya ba tukuna.

Wadannan dalilai sun hada da:

• kwayoyin halittar jini zuwa yaduwar kwayoyin cuta;
• hargitsi a cikin hanyoyin da ake ada adawar a yanzu.

Neoplasm bashi da tsari guda, koda sassan goruwa iri daya na iya bambanta da juna. Launin abin da ke cikin kwayoyin jikinsu ya bambanta kuma yana iya samun inuwa mai haske ko sautunan duhu. Wannan yana bayyana iyawar insulin don samar da da kuma adana abubuwa da yawa na kwayoyin.

Neoplasms marasa aiki, kamar yadda al'adar ke nunawa, galibinsu sunada girman girma, kuma a tsawon lokaci zasu iya girma zuwa cutuka masu muni. Wannan tsarin yana alaƙa da ƙananan alamun cutar, kazalika da ƙarshen gano shi.

Bayyanuwar insulinoma yana taimakawa wajen samar da insulin a cikin adadi mai yawa. Matsanancin matakan hormone a cikin jiki suna haifar da hypoglycemia, lokacin da darajar sukari ke raguwa sosai. Yawancin lokaci ana ɗaukar faruwar irin wannan neoplasm a sakamakon matsaloli tare da glandar endocrine. Theungiyar haɗarin don ci gaban irin wannan cutar ta hada da mutane daga 25 zuwa 55 shekara. Ba a taɓa ganin ilimin halittar yara cikin jarirai ko matasa.

Tushen pathogenesis na halin halayyar ɗan adam na insulinoma shine maganin insulinoma, rashin lafiyar insulinoma ne, wanda baya dogaro da darajar glycemia.

Azumi na dogon lokaci na iya haifar da lafiyayyen mutum ya sauke glucose zuwa ƙasan ƙarancin al'ada, haka kuma raguwa mai yawa cikin adadin kwayoyin.

A cikin mutanen da ke da ƙwayar ƙwayar ƙwayar cuta, ana buƙatar glycogenolysis saboda haɓakar insulin, sabili da haka, in babu ci a cikin glucose daga abinci, ainahin tashin jini yana faruwa.

Idan wannan yanayin yana faruwa akai-akai, to, canje-canje na dystrophic yakan faru a cikin tsarin jijiyoyi da jijiyoyin jini, wanda zai iya haifar da haɓakar ƙwayar cerebral da kuma haifar da ƙwanƙwasa jini.

Symptomatology

Alamomin ciwon farjin cututtukan zuciya na iya bambanta saboda dalilai masu zuwa:

• yawan insulin da aka samar;
• matakai tumo;
• girman insulinoma;
• siffofin masu haƙuri.

Manuniyar alamomin insulinoma sune:

• cututtukan cututtukan jini na haihuwar da suka faru 3 sa'o'i bayan abun ciye-ciye ko babban abincin;
• maida hankali na glucose wanda ke cikin jinin jini shine 50 MG;
• dakatar da alamun hypoglycemia saboda yawan sukari.

Yawancin abin da ke faruwa na hypoglycemia ya rushe aiki da tsarin juyayi (tsakiya da yanki). A cikin lokaci tsakanin irin waɗannan hare-hare, akwai bayyanar cututtuka na jijiyoyi, rashin tausayi, myalgia, raguwar ƙwaƙwalwar ajiya, da kuma damar tunani.

Yawancin waɗannan abn naƙasassun suna ci gaba bayan cire warin, wanda ke haifar da asarar ƙwararrun ƙwararrun ƙwararru da samun matsayi a cikin al'umma. Yanayin cututtukan hypoglycemia wanda ke faruwa cikin maza koyaushe na iya haifar da rashin ƙarfi.

Bayyanar cututtuka na insulinoma an rarraba su cikin yanayin yanayin rashin ƙarfi na hypoglycemia, da kuma bayyanannun bayyanannun harin.

Alamar wani hari

Bayyanar cututtukan jini wanda ke faruwa a cikin mummunan yanayin ya tashi ne saboda farkon abubuwan da ke haifar da damuwa da damuwa a cikin hanyoyin tsarin juyayi na tsakiya. Harin mafi yawan lokuta yakan bayyana ne a kan komai a ciki ko tare da doguwar tsakani tsakanin abinci.

Babban bayyanar cututtuka sune:

• kwatsam na fara ciwon kai mai tsanani;
• daidaituwa ta hanyar aiwatarwa;
• rage ƙarancin gani;
• abin da ya faru na hallucinations;
• Damuwa
• madadin tsoro na tsoro tare da tashin hankali da tsokanar zalunci;
• girgije na hankali;
• rawar jiki yana bayyana a cikin gabar jiki;
• bugun zuciya;
• gumi.

A irin waɗannan lokacin, abubuwan da ke cikin glucose ya ƙasa da 2.5 mmol / L, kuma matakin adrenaline yana ƙaruwa.

Bayyanar cututtuka a wajen harin

Kasancewar insulinomas ba tare da fashewa da wahalar ganowa. Bayyanannun bayanai a bayyane kuma a zahiri basa nan.

Alamu a wajen harin:

• karuwar abinci ko kuma cikakken abinci game da abinci;
• inna
• jin zafi, da rashin jin daɗi a lokacin motsin gira;
• ƙwaƙwalwar ƙwaƙwalwar ajiya;
• lalacewar jijiya ta fuska;
• asarar wasu reflexes da halaye;
• rage aiki na hankali.

Halin da ake alamta bayyanar cututtukan yana faruwa ne a wasu halaye tare da asarar rai ko ma da gudawa. Takaitaccen yanayi na iya haifar da nakasa mutum.

Mutanen da aka tilasta su dakatar da alamun hypoglycemia, a mafi yawan lokuta, sun kasance kiba ko kuma suna da ƙaruwa cikin jiki idan aka kwatanta da abubuwan al'ada. Wasu lokuta alamomin insulinomas na iya haifar da gurɓatar jiki saboda ƙin girman abinci ga kowane abinci.

Binciko

Abubuwan da suka fara bayyanawa na halayyar insulinomas yakamata su zama dalilin gudanar da gwajin ƙwayar cutar mutum.

Iri nazarin karatun:

• dakin gwaje-gwaje (ya kunshi gwaje-gwajen dakin gwaje-gwaje da likita ya tsara);
• aikin;
• kayan aiki.

Bincike na aikin ya hada da:

1. Azumi na yau da kullun - yana ba ku damar sanin rabo na glucose da hormone da aka samar. Godiya ga wannan hanyar, yana yiwuwa a tsokani farkon wani harin na hypoglycemia, wanda zai yuwu a tantance masu mahimman alamomi.
2. Gwajin insulin wanda ke da ƙwarin gwiwa - dangane da gano matakan sukari da ƙimar C-peptide.
3. Gwajin insulin-provocative dangane da gabatarwar glucose domin ya lura da amsawar jikin.

Mataki na karshe ya hada da wadannan karatuttukan kayan aiki masu zuwa:

• scintigraphy;
• MRI (maganin magnetic resonance therapy);
• Duban dan tayi (duban dan tayi);
• catheterization na tsarin tashar don gano neoplasms;
• angiography (bincika ƙari tare da cibiyar sadarwar jijiyoyin jini);
• nazarin radioimmunological - ya bayyana yawan insulin.

Bukatar kowane ɗayan waɗannan karatun an ƙaddara ta likita.

Bidiyo daga Dr. Malysheva wanda aka keɓe shi ga insulinoma, dalilin abin da ya faru da kuma ganewar asali:

Jiyya mai ra'ayin mazan jiya

Magunguna ba zai kawar da tushen cutar ba kuma ba zai haifar da da cikakkiyar murmurewar mai haƙuri ba.

Cases na ra'ayin mazan jiya far:

• ƙi wani mara lafiya ya gudanar da tiyata;
• karuwar hadarin mutuwa;
• Gano metastasis;
• yunƙurin rashin nasara don cire alamar neoplasm.

Hanyoyin magani na Conservative:

• shan kwayoyi masu haɓaka matakin glycemia;
• gudanarwar glucose (a cikin sahun gaba);
• ilimin cutar sankara

Muhimmin sashi na maganin cutar insulinoma shine abinci wanda ya hada da yawan sukari mai yawa.

Turewa

Hanyar sarrafawa da farko shine gano wani ƙari, sannan cire shi. Ana ɗauka tiyata ita ce kaɗai hanyar da za a iya kawar da ciwan.

Insulinoma da aka samo a cikin ƙwayar ƙwayar ƙwayar cuta shine mafi yawan lokuta ana samunsu ne a saman sashin ƙwayar halitta.

Yana da gefuna masu haske, don haka yana da sauƙi a cire. Nearancin ƙananan neoplasms suna da tsari na ƙanjamau kuma maiyuwa ba za'a iya gano su ba a lokacin tiyata.

A irin waɗannan halayen, za a jinkirta cirewar zuwa kwanan wata, lokacin da ƙari ya zama mafi girma. Lokaci na jira don aiki na gaba yana haɗuwa tare da magani mai ra'ayin mazan jiya don hana hypoglycemia da mummunar lalacewar tsarin mai juyayi.

Sake dawowa bayan tiyata yana faruwa a cikin fiye da rabin marasa lafiya. Hadarin mutuwa yana cikin kusan 10% na lokuta. A wasu yanayi, komawa zuwa lokaci na iya faruwa. Yana da mahimmanci a fahimci cewa ganewar asali yana ƙara saurin nasarar warkarwa ga insulinomas.