Atorvastatin-Teva shine sabon ƙarni na statins. Ana daukar magani a matsayin mai tasiri wajen lura da alamun cutar cholesterol mai hawan jini.
Kafin amfani da samfurin, mai haƙuri ya kamata yasan kansa game da cikakken bayani game da samfurin, yin la'akari da kayan aikin, kuma ya kula da bayani game da tasirin sakamako.
Sunan kasa da kasa mai zaman kansa
Atorvastatin, Atorvastatin.
ATX
C10AA05.
Saki siffofin da abun da ke ciki
A cikin cibiyoyin likita da wuraren kantin magani, ana ba da magani a cikin nau'ikan allunan. Na ƙarshen suna haɗuwa a cikin blisters, sannan a cikin fakitoci na takaddun takarda.
Ana amfani da nau'in sashi ta hanyar fim kuma ana nishi a garesu na samfurin. Allunan an gabatar dasu tare da lambobi kamar haka:
- 93 da 7310 a gefe ɗaya na sashi sashi (Allunan 10 mg);
- 93 da 7311 (20 mg kowace);
- 93 da 7312 (40 MG kowace);
- 93 da 7313 (80 MG kowane).
Abubuwan da ke aiki da maganin shine ƙwayoyin atorvastatin.
Atorvastatin-Teva shine sabon ƙarni na statins.
Karin kayan aikin:
- maye gurbin sukari da aka yi amfani da shi a samfuran magunguna;
- nau'in insoluble na ƙananan ƙwayar nauyi polyvinylpyrrolidone;
- Eudragit E100;
- alpha tocopherol macrogol ya maye gurbin;
- gishirin sodium cellulose;
- antihypoxant wanda ke shafar ingancin daidaitawar kwayar halitta idan akwai karancin iskar oxygen.
Babban Layer na kwamfutar hannu ya ƙunshi opadray YS-1R-7003: polysorbate-80, hypromellose 2910 3cP (E464), titanium dioxide, hypromellose 2910 5cP (E464), macrogol-400.
Aikin magunguna
Magungunan ƙwayar cuta shine wakili mai saurin rage ƙwayar cuta wanda ke hana aikin enzyme HMG-CoA reductase. Abubuwan da ke aiki a cikin kwamfutar hannu suna shafar adadin kuzarin cholesterol biosynthesis, yana daidaita matakin lipoproteins a cikin jini, yana ƙaruwa da yawan masu karɓa.
Abunda yake aiki a cikin abun da ke jikin kwamfutar hannu yana shafar adadin kuzarin chosyerol biosynthesis.
A lokaci guda, miyagun ƙwayoyi suna shafar raguwar apolipoprotein B a cikin jini (mai ɗaukar cholesterol da ba dole ba) da triglycerides (mai ɗaukar kitse na jiki).
Don haka, maganin yana rage yiwuwar kamuwa da cututtukan cututtukan jijiyoyin jini, yana hana haɗarin bugun zuciya da bugun jini.
Dangane da nazarin likitanci, ƙwayar ta rage adadin LDL cholesterol da kashi 41-61%, apolipoprotein B - by 34-50%, triglycerides - by 14-33%.
Pharmacokinetics
Abubuwan da ke aiki na miyagun ƙwayoyi suna mayar da hankali ne a cikin jini na jini a cikin minti 30-60.
Abubuwan da ke cikin kwamfutar suna metabolized ta hanta kuma an keɓe su cikin bile har tsawon awanni 14, yayin da suke riƙe da tasirin abubuwan hanawa (har zuwa awanni 30).
Ba a kawar da aiki mai aiki daga jiki tare da tsarkakewar wani abu na jinin.
A cikin cibiyoyin likita da wuraren kantin magani, ana ba da magani a cikin nau'ikan allunan. Na ƙarshen suna haɗuwa a cikin blisters, sannan a cikin fakitoci na takaddun takarda.
Abin da aka wajabta
An hada da magani a cikin warkarwa a cikin halaye masu zuwa:
- Canje-canje na cututtukan cututtukan da ke hade da haɓaka matakin polycyclic lipophilic barasa a cikin jini na jini: firamare, heterozygous dangi da rashin lafiyar familial hypercholesterolemia.
- Increasearawar da ba ta dace ba a matakin lipids da lipoproteins a cikin jini: cakuda ko haɗin hyperlipidemia na nau'in IIa da IIb a cewar Fredrickson. An wajabta jiyya tare da rage cin abinci, wanda abin da ake ci shine abincin don rage girman LDL cholesterol, apolipoprotein B da triglycerides da kuma ƙara yawan cholesterol na HDL.
- Rage matakan beta-lipoproteins da chylomicrons a cikin jini, wanda ke haifar da rashi na bitamin A da E: nau'in dysbetalipoproteinemia a cewar Fredrickson.
- Tsarin triglycerides (nau'in IV a cewar Fredrickson). An wajabta magunguna idan abincin warkewa yana da inganci.
- Homozygous familial hypercholesterolemia, don kawar da abin da hanyar maganin abincin ba shi da tasiri.
- Riskarin hadarin bugun jini, raunin myocardial, angina pectoris.
- Kasancewar dalilai masu haɗari 3 ko sama da haka: jinsi na maza, haɓaka ƙididdigar jiki, tsufa fiye da shekaru 55, hauhawar ventricular, ciwon sukari, matsaloli tare da aikin koda, farji na kashin baya, cututtukan zuciya na hereditary na digiri na farko.
An hada da magani a cikin jiyya tare da ƙara haɗarin bunkasa bugun jini, infarction na zuciya na zuciya, angina pectoris.
Contraindications
A miyagun ƙwayoyi yana da wadannan contraindications:
- rashin haƙuri a cikin abubuwan da ke cikin miyagun ƙwayoyi;
- da rashin ƙarfi ga jiki don ɗaukar lactose;
- rashin sinadarin enzyme Lapp-lactase, ilimin halittar jikin furotin mai dauke da sinadarin glucose da galactose;
- enzymes hanta mai haɓaka;
- m ko cuta na hanta;
- gazawar hanta;
- shirin daukar ciki, lokacin haihuwar yaro ko shayarwa;
- cututtukan neuromuscular (myopathy);
- 'yan tsiraru.
Rashin maganin hepatic shine maganin shan maganin.
Tare da kulawa
Ya kamata a sha miyagun ƙwayoyi da hankali lokacin da:
- cututtukan hanta;
- ba daidai ba musayar abubuwan ganowa;
- kasancewar rikice-rikice a cikin tsarin endocrine da tsarin narkewa;
- m cututtuka (sepsis);
- amai na amai da ba a iya lura da su ba;
- kasancewar raunuka da yawa;
- dysfunction na tsoka na tsarin musculoskeletal;
- shan giya.
A gaban cin zarafi a cikin tsarin endocrine, ya kamata a dauki miyagun ƙwayoyi tare da taka tsantsan.
Mutumin da ya yi aikin tiyata da yawa yayin magani na yau da kullun tare da kwayoyin cutar kwararru ya kamata a duba shi akai-akai ta ƙwararren likita don gano yiwuwar tasirin da ba a so.
Mace da ke amfani da magani tana buƙatar amfani da magungunan hana haihuwa.
Yadda ake ɗaukar Atorvastatin-Teva
Ana bada shawarar magani don amfani kawai idan aka nuna.
Jiyya ya ƙunshi yin amfani da Allunan cikin yarda da daidaitaccen tsarin abinci na hypocholesterolemic.
Lokacin zabar mafi kyawun kashi (10-80 mg), likita yana ɗauka azaman tushen abubuwan da ke nuna alamun bincike, la'akari da la'akari da matakin cholesterol na LDL. Ana gudanar da gwaje-gwaje na sarrafawa don daidaita hanyar magani da aka zaɓa duk ranakun 14-28.
A cikin hypercholesterolemia na farko da haɗin hyperlipidemia, daidaitaccen sashi shine 10 MG a cikin 24 hours.
Tare da hyzycholesterolemia na homozygous - 80 MG kowace rana.
Game da keta hadarin lipid - 10 MG cikin awa 24. Yayin binciken likita, likitan yana daidaita kuma idan ya cancanta, ya karu zuwa 80 MG.
Tasirin shan magani ya bayyana bayan sati 2.
Ana bada shawarar magani don amfani kawai idan aka nuna.
Shan maganin don ciwon sukari
Tare da yin amfani da statins, matakan glucose na jini suna ƙaruwa, don haka ci gaban hyperglycemia mai yiwuwa ne.
Side effects
Gastrointestinal fili
Mafi sau da yawa, sakamako masu illa suna faruwa a cikin nau'in ciwon ciki, ƙwannafi, tashin zuciya, bloating da maƙarƙashiya. Wadannan abubuwan mamaki suna raunana yayin aikin jiyya.
Abubuwa masu haɗari masu haɗari sun haɗa da kumburin ciki, kumburi ko mucous membrane na esophagus, choraasis intrahepatic da anorexia.
Tsarin juyayi na tsakiya
A wasu halaye, mai haƙuri na iya bayyana:
- Dizziness
- ciwon kai
- janar gaba daya da malaise;
- asarar ƙwaƙwalwar ajiyar lokaci;
- rikicewar ji na jijiya (azanci na gosebumps, ƙonawa mai ƙarfi, abin mamakin hankali);
- rage ji na ƙwarai zuwa ga motsawar waje;
- lalacewar jijiyoyin mahaifa;
- rashin bacci da daddare;
- cutar asthenic.
A wasu halaye, mai haƙuri na iya fuskantar zazzabin cizon sauro da rauni gaba ɗaya.
Daga tsarin numfashi
Wadannan sakamako masu illa suna iya yiwuwa:
- asma;
- yada yaduwar cutar huhu;
- kumburi hanci na mucosa;
- ciwon huhu
A ɓangaren fata
A wasu halaye, raunuka da blister suna fitowa akan fatar mai haƙuri sakamakon halayen rashin lafiyan. Wataƙila samuwar ƙwayar cuta ta polymorphic a kan ƙwayar ciki da ƙwayoyin mucous, bayyanar eczema da seborrhea, haɓakar ƙwayoyin cuta mai guba.
A wasu halaye, raunuka da blister suna fitowa akan fatar mai haƙuri sakamakon halayen rashin lafiyan.
Daga tsarin kare jini
Yin amfani da miyagun ƙwayoyi na iya haifar da:
- urin yawan urination;
- rashin daidaituwa;
- pollakiuria;
- yawan cin abinci na dare a cikin dare;
- leukocyturia;
- bayyanar jini a cikin fitsari;
- rashin ƙarfi da take hakkin cizon sauro;
- kumburi da prostate.
Daga tsarin zuciya
A wasu marasa lafiya, lokacin shan kwayoyin, yawan platelet a cikin jini yana raguwa, kumburi da bangon venous yana faruwa, anemia, arrhythmia da angina sun haɓaka.
Daga tsarin musculoskeletal
Wasu marasa lafiya suna zuwa haske:
- rashin jin daɗi da jin zafi a cikin ƙananan kashin baya;
- cramps tsoka da hauhawar jini;
- lalacewar tsoka;
- matsanancin matakin cutar ciwon sanyi;
- amosanin gabbai;
- m zafi a cikin gidajen abinci.
Sakamakon sakamako daga tsarin musculoskeletal: amosanin gabbai.
Cutar Al'aura
Kamar yadda rashin lafiyan halayen ke yiwuwa:
- urticaria;
- itching
- kurji
- girgiza anaphylactic;
- kumburi da fata, kasala mai ƙyalli ko membran mucous.
Umarni na musamman
Amfani da barasa
Yin amfani da allunan a lokaci guda tare da barasa yana inganta sakamako masu illa, yana cutar da jin daɗin haƙuri.
Yin amfani da allunan a lokaci guda tare da barasa yana inganta sakamako masu illa, yana cutar da jin daɗin haƙuri.
Tasiri kan ikon sarrafa abubuwan inji
Idan waɗannan sakamako masu illa sun faru, an haramta tuki da kansu.
Yi amfani da lokacin daukar ciki da lactation
Bai kamata a sha magungunan ba yayin daukar ciki da shayarwa.
Alƙawarin Atorvastatin-Teva ga yara
Magungunan yana contraindicated a cikin yara.
Magungunan yana contraindicated a cikin yara.
Yi amfani da tsufa
Tsofaffi ba tsufa ba ne don amfani da maganin na baka: haɗarin sakamako masu illa ba sa ƙaruwa, tasiri na miyagun ƙwayoyi baya raguwa.
Aikace-aikacen aiki mara kyau
Allunan yakamata a cinye ƙarƙashin kulawar likita.
Amfani don aikin hanta mai rauni
An haramta yin amfani da miyagun ƙwayoyi a cikin siffofin m da na kullum na cututtukan hanta, kazalika da haɓaka mara kyau a cikin matakan transaminases a cikin jini (3 ko fiye da sau idan aka kwatanta da na al'ada).
An haramta yin amfani da miyagun ƙwayoyi a cikin matsanancin yanayi da cututtukan cututtukan hanta, har ma da haɓaka mara kyau a cikin matakan transaminases a cikin jini.
A cikin marasa lafiya da renal gazawar
A wannan yanayin, likitan halartar yana yin gwaje-gwaje na yau da kullun na mara lafiya, bayan wannan za a iya tsara magunguna a rage rage-rage rage ƙwayoyi ko ragewa.
Yawan damuwa
Tare da wuce haddi na aiki mai narkewa a cikin jiki, mai haƙuri yana da alamu masu zuwa:
- ji na bushewa da daci a cikin bakin;
- tashin zuciya da amai
- dyspepsia.
Tare da wuce haddi mai aiki a cikin jiki, mai haƙuri na iya fuskantar tashin zuciya.
Idan aka samu yawan zubar da jini, ana yin layin ciki, sai a sanya idanu a kan matakin CPK a cikin jini.
Yin hulɗa tare da wasu kwayoyi
Abubuwan haɗin gwiwa
A yayin jiyya, wajibi ne don ware amfanin:
- fibrates;
- maganin rigakafin macrolide;
- nicotinic acid;
- wakilan antifungal na bakin ruwa;
- ruwan 'ya'yan innabi.
A yayin jiyya, wajibi ne don ware amfani da ruwan 'ya'yan innabi.
Ba da shawarar haɗuwa ba
Ba a da amfani da miyagun ƙwayoyi don amfani dashi tare da:
- Cyclosporine;
- Masu hana HIV kariya;
- Nefazodone;
- wakilai waɗanda ke rage taro na kwayoyin steroid endogenous.
Haɗuwa yana buƙatar taka tsantsan
An shawarci mara lafiya ya ba da rahoton duk wani yanayin rashin lafiyar a cikin likitan halartar idan ana amfani da allunan lokaci guda tare da:
- P-glycoprotein inhibitors;
- Digoxin;
- maganin hana haihuwa wanda ke dauke da sinadarin ethinyl estradiol da norethisterone;
- Colestipol;
- Warfarin.
An shawarci mai haƙuri ya ba da rahoton duk wani lamari na lalacewa a cikin lafiyar ga likitan halartar idan ana amfani da allunan lokaci guda tare da masu hana-P-glycoprotein.
Analogs
Sauya magunguna, waɗanda suka haɗa da abubuwa masu kama:
- Abita
- Actastatin;
- Astin;
- Atomax;
- Atocor
- Atorem;
- Atoris;
- Atorvastatin;
- Atorvastatin alkaloid;
- Atorvastatin-LEXVM;
- Atorvastatin-SZ;
- Vazator;
- Lipoford;
- Liprimar;
- Novostat;
- Torvazin;
- Torvacard
- Torvas
- Tulip
Wanne ya fi kyau - Atorvastatin ko Atorvastatin-Teva?
Kafin yanke shawara game da amfani da irin wannan kwayoyi, ba tare da la'akari da dalilin ba, mai haƙuri ya kamata yayi nazarin bayanin game da allunan kuma yayi shawara da likitanka game da yiwuwar maye gurbin.
Sunan Atorvastatin (ba tare da ƙara sunan mai ƙira ba) yana nuna cewa ƙungiyar ta ƙirƙira magungunan ne wanda wataƙila ba amintaccen mai ba da magunguna ba ne.
Magunguna kan bar sharuɗan
Ana bayar da allunan gwargwadon maganin, wanda ya ƙunshi sunan magani a cikin Latin, an rubuta shi a kan shafin ƙungiyar likitocin kuma bokan tare da hatimi.
Zan iya siye ba tare da takardar sayan magani ba
Akwai lokuta na sayen magani ba tare da takardar sayan magani ba (ta shagunan kan layi). Amma shan magani ba tare da nadin kwararrun na iya haifar da cutarwa ba ta shafi lafiyar mutum.
Ya kamata a adana miyagun ƙwayoyi daga isar yara a yanayin zafi da ke ƙasa da 30 ° C.
Atorvastatin-Teva Farashin
Kudin magungunan daga wani kamfanin Isra’ila ya bambanta daga 95 zuwa 600 rubles. ya dogara da sashi da wurin siyarwa.
Yanayin ajiya na miyagun ƙwayoyi
Ya kamata a adana miyagun ƙwayoyi daga isar yara a yanayin zafi da ke ƙasa da 30 ° C.
Ranar karewa
Ba a wuce shekaru 2 ba daga ranar fitarwa.
Mai masana'anta
Kamfanin - Kamfanin masana'antar harhada magunguna ta Teva, Isra'ila.
Atorvastatin-Teva Reviews
Likitoci
Vitaliy, dan shekara 42, Ufa
Magungunan daga Teva an samar da shi ta hanyar kamfanin samar da magunguna na amintattu, don haka an wajabta wannan maganin don marasa lafiya tare da ingantaccen ganewar asali. Wasu lokuta marasa lafiya suna korafi game da rashin ingancin maganin. Koyaya, bayan buƙatarta don nuna kunshin da aka saya, an gano cewa wani kamfanin wanda ba a san shi ba ya samar da maganin.
Irina, ɗan shekara 48, Stavropol
Wajibi ne don amfani da maganin kamar yadda likita ya umarta kuma kawai in babu contraindications. A cikin aikin mutum, akwai wani yanayi idan mai haƙuri da cutar hanta ya fara shan kwayoyin magani ba tare da tuntuɓar ƙwararren likita ba, wanda ya haifar da babbar illa ga lafiyar kansa.
Renat, 37 years old, Rostov-on-Don
Bai kamata masu haƙuri su manta da illolin da miyagun ƙwayoyi ke haifar ba. Lokacin amfani da allunan, an shawarci masu haƙuri da su yi gwajin jini na ƙwayoyin cuta akai-akai.
Marasa lafiya
Ilya, 38 years old, Surgut
Don watanni 3 sakamakon rage cin abinci da shan magani, matakin LDL cholesterol ya ragu zuwa 3 mmol / L. Sabili da haka, zan iya faɗi cewa allunan suna da tasiri, suna rarrabewa a cikin wannan ƙananan farashi. Ina yaba shi.
Alexandra, ɗan shekara 29, Izhevsk
An wajabta magungunan mama don rage cholesterol. Watanni 3 sun shude, amma babu sakamako. Amma taro na sakamako masu illa - rashin bacci, ciwon kai, ciwon baya.
Marina, shekara 32, Voronezh
Na yi imani cewa idan akwai matsaloli tare da cholesterol, to ya fi kyau ku bi cin abinci ku ci gaba da ƙari. Magungunan ba ya shafar matakin shan barasa, amma yana haifar da tashin zuciya da ciwon kai. Ta dauki kwayoyin hana daukar ciki kan shawarar likitocin da ke halartar taron ban fahimci abin da yake jagorarsa ba lokacin da ake rubuta irin wannan magunguna ga marasa lafiya. Vasator yana daya daga cikin alamun magungunan.
