Glucophage magani ne mai haɓaka, wanda ya haɗa da metformin, wani sashi wanda ke da tasirin antidiabetic sakamako.
Aiki mai amfani na miyagun ƙwayoyi yana kawar da hyperglycemia ba tare da rage yawan cututtukan jini ba. Ba ya haifar da samar da insulin da kuma yanayin hypoglycemic a cikin mutane masu lafiya.
Yana haɓaka karɓar mai karɓa zuwa ƙwayar peptide kuma yana haɓaka aiki da carbohydrates mai sauƙi. Yana rage haɓakar glucose ta hanzarta haɓaka metabolism da rushewar glycogen. Yana hana shan abubuwa masu sauki a cikin abinci ta hanyar narkewa.
Metformin yana kunna glycogenesis, yana haɓaka ƙarfin jigilar ƙwayar glucose, ingancin metabolism na lipid. Sakamakon shan Glucofage, nauyin mai haƙuri a hankali yana raguwa. Bincike ya tabbatar da kayyakin maganin ƙwayoyin cuta na maganin ƙwaƙwalwar ƙwayar cuta ta Glucophage a cikin daidaikun mutane tare da ci gaba da karuwa a cikin glukos din jini da abubuwan haɗari.
An nuna magungunan ga wadanda suka kamu da cutar, wadanda bayan sun canza hanyar rayuwarsu ta yau da kullun, ba su kai matsayin yanayin glycemic ɗin su ba. Yadda zaka sha Glucofage don kauracewar yawan zubar jini da sakamako masu illa za'a iya samu a bayanin da aka bayar a kasa.
Abun haɗin kai da siffofin sashi
Sashin aiki mai magani ya ƙunshi metformin hydrochloride, ƙananan nauyin polyvinylpyrrolidone, magnesium stearate.
Allunan glucophage
Round, farin biconvex allunan 500 da 850 MG an hade su da fim na hypromellose. Wani farin taro mai hade da juna yana nan a sashin giciye.
M, 1000 mg farin allunan convex a garesu suna da fim na opadra, layin rarraba da rubutu "1000".
Alamu don amfani
Abubuwan da ke aiki da maganin suna inganta metabolism na fats, yana taimakawa kawar da lipoproteins na atherogenic da cholesterol.
Babban alamun alamun amfani da miyagun ƙwayoyi sune kamar haka:
- cututtukan da ba su da insulin-da ke fama da ƙura a cikin kiba da kuma rashin sakamakon amfani da abinci mai gina jiki ko aikin jiki;
- a cikin tsofaffi marasa lafiya da yara fiye da shekaru 10 a matsayin mai zaman kanta magani na type 2 ciwon sukari ko a layi daya da wasu magunguna-rage jini glucose jini;
- rigakafin kamuwa da ciwon sukari na 2 a cikin yanayin kan iyaka.
Contraindications
Kamar kowane magungunan asalin sunadarai, glucophage yana da iyakoki da yawa.
An haramta shan miyagun ƙwayoyi a cikin halaye masu zuwa:
- rashin ƙarfi ga metformin, ƙarin abubuwa na miyagun ƙwayoyi;
- halin hyperglycemia, ketoanemia, precoma, coma;
- aikin cututtukan koda
- canji cikin daidaita-ruwa-gishiri;
- mummunan cututtukan raunuka;
- kasawa gazawar tsarin tafiyar da rayuwa;
- take hakkin musayar gas a cikin huhu;
- decompensated myocardial tabarbarewa tare da m jini wurare dabam dabam;
- m ischemic necrosis;
- babban aiki da raunin da ke buƙatar maganin insulin;
- rikicewar aiki na hanta;
- jaraba na kullum da giya, guba na ethanol;
- ciki
- ƙara yawan lactate jini;
- hanyar scintigraphy ko daukar hoto tare da gabatar da wani bambancin magani wanda ya ƙunshi aidin;
- yarda da karancin kalori.
Ana amfani da glucophage a hankali cikin yanayin da ke gaba:
- babban aiki na jiki a wani tsufa, wanda zai iya haifar da samuwar lactic acidosis;
- rashi mai aiki;
- lactation zamani.
Sashi da sashi na tsari don kamuwa da cutar siga
Ana sarrafa maganin glucophage a baki.Da zarar cikin narkewa, narkewar metformin yana kasancewa cikakke.
Cikakken bayanin halitta ya kai kashi 60%. Matsakaicin maida hankali ne ake lura da awa 2.5 bayan aikace-aikacen.
Abincin lokaci guda na abinci yana jinkirta ɗaukar abin da ke aiki. Metformin da sauri yana cika kyallen takarda ba tare da ma'amala da furotin ba.
Samfarin hypoglycemic yana aiki da rauni na rayuwa. An cire shi saboda narkewar ƙodan na cikin ƙasa da kuma tasirin aiki mai aiki. Cire rabin rayuwa shine awoyi 6.5. Abubuwan da ke tattare da ƙwayoyin ƙwayoyin cuta na haɓaka lokacin tazara, suna haifar da haɗarin tara abubuwa masu guba.
Ana amfani da miyagun ƙwayoyi yau da kullun, ba tare da hutu ba.Ga manya, adadin yau da kullun na abu - 500 ko 850 MG an kasu kashi biyu ko 3 amfani. Ana cinye shi da abinci ko bayan sa. Kowane sati 2, ana sanya ido kan abubuwan da ke cikin suga na jini. Dangane da alamun da aka samo, ana yin gyara.
Increasearawar hankali a hankali yana hana mummunan tasirin narkewar abinci. Tsarin magani na yau da kullun yana shan nauyin 1500-2000 mg. Yawan halatta shine 3000 MG. An kasu kashi uku.
Ga marasa lafiya da ke amfani da metformin a cikin adadin 2000-3000 MG a rana, yana da kyau a sauya zuwa allunan kwayar mg 1000. An rarraba girman yau da kullun zuwa amfani 3.
Haɗin magani tare da insulin yana taimakawa sarrafa glucose jini. Adadin farko na maganin shine 850 MG. An kasu kashi biyu ana amfani da shi. An zaɓi kashi na hormone peptide dangane da sukarin jini.
Anyi maganin Glucophage ga yara sama da 10. An ba da izinin yin amfani da insulin. Volumearamar yau da kullun shine 500 ko 850 MG. Takeauki lokaci 1 a rana tare da ko bayan abinci. Bayan mako biyu, ana aiwatar da gyaran jiyya. Matsakaicin adadin yau da kullun - 2000 MG ya kasu kashi biyu.
Side effects
Wani lokacin glucophage yana haifar da halayen da ba'a so na jiki. Wadannan mummunan yanayi mai yiwuwa ne:
- lactic acidosis;
- isasshen sha na bitamin B 12;
- rashin abubuwan dandano na zahiri;
- nauyi a ciki, amai, yawan motsin hanji, zafin ciki;
- canje-canje a cikin sigogi masu aiki na hanta, hepatitis.
Nazarin a cikin rukuni na yara daga shekaru 10 zuwa 16 sun tabbatar da kasancewar tasirin sakamako masu kama da mummunar illa a cikin marasa lafiyar manya.
Yawan damuwa
Excessimar mahimmancin adadin allurai ko yanayi masu dangantaka suna haifar da haɓakar lactate. Bayyanar bayyanar cututtuka na karuwa a cikin lactic acid na buƙatar dakatar da magani, asibiti cikin gaggawa don tsarin tsarkake jini da lura da alama.
Yin hulɗa da giya
Yin amfani da wakilin antidiabetic da ethanol ba tare da bada shawara ba.
Shan barasa yana haifar da lactic acidosis a cikin waɗannan yanayin concomitant:
- Rashin abinci
- abinci mai karancin kalori;
- cuta cuta hanta.
Haihuwa da lactation
Rashin sakamakon maganin rigakafi a lokacin haihuwar yaro ya zama sanadin lalacewar cutar mahaifa da mace-mace a cikin cikin haihuwarsa.
Ba a samun bayanai game da karuwar yiwuwar rashin ƙarfi a cikin jarirai yayin da mata masu juna biyu ke shan Glucofage.
Idan an gano gaskiyar yanayin ciki ko kuma game da shirin daukar ciki, an soke maganin. Metformin yakan shiga cikin madarar nono.
Ba a gano mummunan tasirin miyagun ƙwayoyi a cikin jarirai ba, amma iyakantaccen adadin bayanai yana nuna rashin amfani da samfurin samfuran jini a wannan lokacin.
Abun Harkokin Magunguna
Haɗin haɗari shine amfani da metformin tare da kayan aikin radipaque wanda ke ɗauke da aidin. A kan asalin ilimin cutar koda, irin wannan binciken yana ba da gudummawa ga ci gaban lactic acidosis.
An soke amfani da miyagun ƙwayoyi kwana biyu kafin binciken. Ci gaba bayan awa 48 a karkashin aikin koda.
Haɗin Glucophage tare da kwayoyi da aka lissafa a ƙasa an bayyana su kamar haka:
- Danazole ya tsokani tasirin maganin metformin;
- Chlorpromazine a cikin manyan kundin yana ƙara yawan adadi na carbohydrates mai sauƙi, rage sakin hormone peptide;
- analogues na kwayoyin halittar endogenous suna kara yawan glucose, suna haifar da rushewar kitse da aka adana;
- diuretics suna tsokanar lactic acidosis a gaban rashi na aiki na kasawa;
- injections na beta2-adrenergic agonists suna kara maida hankali ne akan glucose jini;
- magungunan rigakafi, tare da banda masu toshewar ACE, rage yawan adadin glucose;
- amfani da maganin a lokaci guda tare da abubuwan da suka samo asali na sulfonylurea, hormones na peptide, alhib-glucosidase inhibitors, salicylates yana tsokani rashin lafiyar hypoglycemia;
- Nifedipine yana haɓaka tsarin sinadarai na ɗaukar abubuwan da ke aiki;
- cationic antibacterial jami'ai gasa tare da metformin don tsarin jigilar salula, ƙara matsakaicin adadi na adadin.
Sharuɗɗan sayarwa da ajiya
Ana bayar da maganin ne kawai ta hanyar takardar sayan magani. Zafin ajiya - har zuwa 25 ° C. Ayi nesa da isar yara.
Shin zai yiwu a rasa nauyi daga miyagun ƙwayoyi
Akwai shawarwari don cimma nauyi mai nauyi ba tare da lahani mai yawa ga lafiyar ba. Ana zaɓin farashin magani na mutum da likitan halartar.
Fara da karamin taro, matsa zuwa wani karuwa a hankali. Yi amfani da wakili na hypoglycemic a kan asalin tsarin abinci mai kyau.
Bidiyo masu alaƙa
Dietitian game da tasirin glucophage:
