Jerin magungunan antihypertensive don ciwon sukari na 2

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Magungunan rigakafin ƙwayoyin cuta na ƙwaƙwalwar ƙwayar cuta ta 2 na mellitus an zaɓi su daban-daban, suna ba da tasirin tasirinsu ga ayyukan ƙodan, sakamakon tasirin tasirin mai-mai da fitsari. Rashin hauhawar jijiyoyin jiki yana tare da kashi 80% na waɗanda ke fama da cututtukan hawan jini. Cututtuka suna taɓarɓare aikin gabobin ciki, suna rushe tsarin aikin metabolism.

Siffofin

Magungunan kwayar cutar kwayar cutar don masu ciwon sukari yana da rikitarwa ta hanyar illa wanda ba a ke so, bayyanuwar hakan wanda ke haifar da lalacewar ƙwayar jijiya.

Zaɓin magunguna don hauhawar jini tare da hauhawar jini ya dogara da yanayin:

  • Ingantaccen aiki, ƙaramar sakamako;
  • Cardio da sakamako nephroprotective (kariya daga zuciya da kodan);
  • Babu wani tasiri a cikin taro na lipids da glucose a cikin jini.

Magunguna masu sauri

Idan kana iya saurin jikewar jini a cikin jini, yakamata a sami magunguna masu dacewa don hauhawar jini a cikin ciwon sukari.

Amfani da abubuwan da bazasu iya haifar da haɓakar insulin a cikin masu ciwon sukari ba a yarda da su ba.

Idan taimakon gaggawa ya zama dole, amfani na nufin wanda tasirin jikin sa bai wuce awa 6 ba. Abubuwan da ke aiki waɗanda sune ɓangare na sunayen kasuwanci na gama gari na magunguna:

  • Kyaftin
  • Nifedipine;
  • Clonidine;
  • Anaprilin;
  • Andipal.

Magunguna don amfani da tsari

Karatun mai tsayi sama da 130/80 mm Hg. Art. don masu ciwon sukari suna da rauni tare da rikicewar microvascular, haɓakar atherosclerosis, ci gaba na angiopathies na ciwon sukari. A wannan yanayin, ana bada shawarar amfani da kwayoyi akai-akai, yayin da ake bin abinci mai gishiri da abinci mai narkewa. Sakamakon magungunan hawan jini ga masu ciwon sukari yakamata suyi laushi. Rage saukar karfin jini da tsalle-tsalle yana lalata ko da ga tsarin zuciya na mutum ne mai lafiya.

ACE masu hanawa

Don daidaituwa na hankali na bayyanar cututtuka na hauhawar jini, ana amfani da toshewar angiotensin-mai canza enzyme (ACE), wanda ke ƙarfafa tsarin angiotensin. Ta rage yawan haɗarin angiotensin, glandon adrenal yana samar da ƙirar aldosterone da ke ƙasa, wanda ke riƙe da sodium da ruwa a cikin jiki. Vasodilation na faruwa, an zubar da ruwa mai yalwa da gwal, ana nuna sakamako mai narkewa.

Abubuwa masu aiki waɗanda ke toshe ACE:

  • Enalapril;
  • Perindopril;
  • Quinapril;
  • Fosinopril;
  • Trandolapril;
  • Ramipril.

Suna halin aikin nephroprotective (jinkirin tafiyar matakai), kada ku keta metabolism na carbohydrates, lipids, insulin juriya.

Rashin dacewar masu hanawa shine ikon jinkirta kawar da potassium da jinkirin tasiri. Ba a tantance sakamakon aikin ba kafin makonni biyu bayan alƙawarin.

Manyagun Maƙallan Raji (ARBs)

Sun toshe tsarin kira na renin, wanda ke tayar da canji na angiotensin, wanda ke haifar da katangar ganuwar jijiyoyin jini. An tsara ARBs idan an ƙaddamar da rashin haƙuri ga ACE inhibitors. Hanyar dabarun nazarin halittunsu daban ne, amma maƙasudi iri ɗaya ne - don rage tasirin cututtukan angiotensin da aldosterone.

Ana kiran kungiyar sartan a ƙarshen sunayen abubuwa masu aiki:

  • Losartan;
  • Valsartan;
  • Irbesartan
  • Kayani

Diuretics

Diuretics suna da sakamako mai sauƙi na hypotonic, ana tsara su ne ta hanyar haɗin kai ta amfani da wasu kwayoyin cutar hawan jini don ciwon sukari.

  1. Diptip diuretics (furosemide, lasex) haɗuwa sosai tare da masu hana ACE, ba su shafi matakin sukari, lipids, kuma sun dace da amfani na ɗan lokaci don kawar da kumburi mai ƙarfi na kyallen takarda. Amfani da shi ba tare da izini ba yana haifar da hanzarta kawar da potassium, wanda zai iya tsokani haɓakar hypokalemia da cututtukan zuciya.
  2. Sakamakon sakamako mai sauƙi na diuretic, thiazide-kamar diuretics (indapamide) ba sa tayar da daidaituwa na glucose, mai acid, matakan potassium, kuma baya shafar aikin halitta na kodan.
  3. Thiazide diuretics (hypothiazide) a cikin abubuwan yau da kullun da suka wuce 50 MG sun sami damar haɓaka matakan glucose da cholesterol. An wajabta su da taka tsan-tsan a cikin allurai kaɗan saboda yiwuwar lalacewar kumburin koda da gout.
  4. Abubuwan da ke amfani da daskararren potassium (veroshpiron) ba a ba da shawarar yin amfani da su ba a cikin nau'in ciwon sukari na 2 na sukari, tare da aiki na keɓaɓɓu.

Masu tallata Beta

Akwai kwayoyi da yawa waɗanda ke toshe ƙwayoyin adrenoreceptors ta adrenaline da norepinephrine an sanya su da farko don kula da ischemia, cardiosclerosis, gazawar zuciya. Tare da hauhawar jini, an zaɓi Allunan don hauhawar jini tare da ƙarin tasirin vasodilating:

  • Labetalol;
  • Carvedilol;
  • Nebivolol.

Ayyukan B-blockers na iya haifar da sakamako wanda ke rufe bayyanar cutar glycemia, saboda haka an umurce su da taka tsantsan, da sarrafa yawan glucose.

Masu maganin kishi

Hanyoyin toshiyar alli - rukuni na kwayoyi waɗanda ke rage maida hankali na ions cium alli. Sake shakatawa da fadada ganuwar tasoshin jini, arteries, sel mai santsi. An kasaftawa gida kashi-kashi:

  1. Verapamil, diltiazem. Shafar aikin myocardium da ƙwayoyin zuciya, rage yawan zuciya. Amfani da haɗin kai tare da beta-blockers an hana shi.
  2. Abubuwan da ke haifar da dihydropyridine - nifedipine, verapamil, nimodipine, amlodipine. Sukan kwantar da bangon tsoka mai laushi, suna kara yawan zuciya.

Magungunan calcium ba su tsoma baki tare da carbohydrate, metabolism na lipid. Lokacin amfani dashi azaman magani don matsa lamba, nau'in ciwon sukari na 2 ya fi dacewa, amma yana da yawan contraindications. Nifedipine yana contraindicated a cikin angina pectoris, zuciya da gazawar koda, sun dace da sauƙaƙawar matsala. Amlodipine na iya tayar da kumburi. Verapamil yana da sakamako mai laushi ga aikin kodan, amma yana iya haifar da masu aikin jijiyoyin zuciya.

Mutane daya-daya dauki

Ana haɗaka magungunan rigakafi tare da juna, an zaɓi yin la'akari da cututtukan haɗin gwiwa, magunguna da aka dauka. Rashin hauhawar jini, tare da raunin cutar kansar ƙwayar ƙwayar mahaifa, yana haifar da halayen masu yawa.

Kafin amfani, ya kamata kuyi nazarin jerin tasirin sakamako, hanyoyin kawar dasu.

Lokacin ɗaukar, ana lura da kuzari da karfin jini. A lokaci guda, ana kula da matakin glycated haemoglobin, cholesterol, triglycerides, glucose mai azumi kuma bayan cin abinci ana kulawa. Rashin daidaituwa daga matakin da aka yarda da shi yana buƙatar sauya magunguna.

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