An ba da shawarar Rosulip don rage ƙwayar cholesterol. Ana amfani dashi don ciwon sukari mellitus, atherosclerosis, hauhawar jini da sauran cututtukan zuciya. Babban abu tare da aikin kwayoyin halitta shine rosuvastatin.
Rosuvastatin magani ne na statin. Theungiyar yana haɓaka ɗaukar ƙwayar abinci na lipoproteins da triglycerides a cikin hanta mai haƙuri. Ba'a bayyana magungunan ta hanyar aiki mai sauri. An lura da warkewar cutar mako guda bayan aikace-aikacen.
Bayan wata daya na magani, an lura da ƙarin sakamako mai ma'ana. Yana da wannan a cikin tunanin cewa sun yanke shawara ko za a ci gaba da maganin jiyya ko don yin kwatankwacin maganin da ake amfani da shi idan tasirin bai isa ba a cikin mai haƙuri.
Ana samun magungunan a cikin nau'in kwamfutar hannu, kashi daban-daban. Yi la'akari da menene tasirin magungunan ƙwayar cuta lokacin da yake da kyau a yi amfani da shi, kuma idan aka zaɓi irin waɗannan magunguna?
Fitar saki da alamu don amfani
Rosulip yana samuwa a cikin kwamfutar hannu. Kowane kwamfutar hannu mai shigarda kayan shiga ciki. Allunan suna zagaye ko m, launinsu fari ne ko pastel, a gefe guda akwai zane da ke harafin "E", a gefe guda akwai lambobi dake nuna sashi. Misali, lambar 591 tana nufin cewa sashi shine milligram 5, kuma lambar 592 tayi daidai da 10m na sashi mai aiki.
A kantin magani zaka iya siyan Rosulip 10 mg da 5 mg, 20 da 40 mg. Likita ya ba da magani ga masu ciwon sukari, ba za ku iya ɗaukar kanku ba. Baya ga bangaren aiki, an hada kayan taimako. Musamman, povidone, lactose monohydrate, magnesium stearate, crospovidone da sauran abubuwan haɗin.
Magunguna a kan asalin aikace-aikacen yana da tasirin rage ƙwayar cuta, yana cikin rukunin magunguna na ƙirar gumakan.
Alamu don amfani da maganin:
- Jiyya na farko na nau'in 2a hypercholesterolemia. Ana amfani da nau'in 2b azaman haɗin kai don abinci mai gina jiki.
- A hade tare da tsarin inganta lafiyar abinci da sauran hanyoyin kwantar da hankali na likitancin da aka yi niyya don rage yawan ƙwayar fitsari a cikin jiki tare da kamannin halittar jini na hyzycholesterolemia.
- Increasedara yawan taro na triglycerides a cikin jinin mai haƙuri (an haɗa Allunan tare da abinci).
- A hade tare da daidaitaccen abinci da kulawa da ra'ayin mazan jiya da aka mayar da hankali kan rage yawan cholesterol a cikin masu ciwon sukari waɗanda ke da tarihin ci gaba na atherosclerosis.
Ana amfani da kayan aiki azaman prophylaxis na rikitarwa daga zuciya da jijiyoyin jini. Yana rage hadarin bugun zuciya, bugun jini. An ba da shawarar don farfadowa na jijiya na hanya ta asymptomatic, amma tare da haɓakar haɗarin haɓakar cututtukan zuciya na zuciya.
An wajabta shi a gaban waɗannan abubuwan masu tayar da hankali kamar hauhawar jini, ƙananan taro na cholesterol mai yawa; idan tarihin dangi yana da maganganun ci gaban farkon cutar sankarau.
An shawarci masu ciwon sukari suyi yayin da abun LDL ya wuce raka'a 3.
Idan an gano tarihin cutar cututtukan zuciya, to likitan kwalliyar ne ya tsara shi, ba tare da la’akari da matakin cholesterol ba.
Aikin magunguna da magunguna
Rosuvastatin a matsayin sashin aiki mai aiki ya bayyana a matsayin mai hanawa mai haɓakar enzyme na HMG-CoA, wanda ke taimakawa canza wasu abubuwa zuwa mevalonate, sanannen ƙwayar cholesterol.
Sakamakon karuwa a cikin taro na low yawa cholesterol a hepatocytes a ƙarƙashin rinjayar abu mai aiki, ana ɗaukar tsarin sha da catabolism na mummunan cholesterol. Hakanan ana takaddama ayyukan keɓaɓɓiyar ƙwayoyin tsoka a cikin hanta.
Matsakaicin tasirin warkewar maganin yana ba ku damar samun raguwa mai sauƙi amma ci gaba a cikin LDL, wanda ke rage yiwuwar rikitarwa daga zuciya da jijiyoyin jini.
Abubuwan da ke cikin magungunan magungunan sune kamar haka:
- Abinda ke cikin cholesterol mai yawa a jikin masu ciwon sukari yana ƙaruwa;
- Yawan LDL da jimlar cholesterol, triglycerides an rage su;
- Matsayi na apolipoprotein A-I yana ƙaruwa;
- Matsayi na apolipoprotein B. yana raguwa.
Kayan aiki yana da kayan tarawa, saboda haka an bayyana ci gaba na farko bayan mako guda kawai. Matsakaicin mafi girman abubuwan da ke aiki a cikin jinin mutum ana iya cimmawa bayan makonni 3-4 na amfani - a wannan matakin, ƙwayar tana ba da sakamako 90% na yuwuwar.
Matsakaicin abun cikin abu akasin asalin amfani da tsari an gano shi sa'o'i biyar bayan aikace-aikacen. A bioavailability na miyagun ƙwayoyi shine 20%; yana jin daɗin ƙaruwa gwargwadon aikin da aka tsara.
Rosuvastatin, hanta ta dauke shi, tana ma'amala da cholesterol, sakamakon abin da ke da ƙanƙantar ƙwaƙwalwar ƙone yana ƙonewa. Aƙalla kashi 90% na aiki a jikin ɗan adam ya ƙunshi abubuwan haɗin furotin.
Kusan 90% na maganin da aka yarda an cire shi ta halitta tare da feces, kusan 5% suna barin jiki a cikin koda.
Rabin rayuwar miyagun ƙwayoyi shine 18-19 hours (ba ya dogara da matakin da aka ɗauka ba).
Umarnin don amfani da miyagun ƙwayoyi
Yadda ake ɗaukar Rosulip 10MG zai gaya wa likitan halartar. Kuna buƙatar siyan magani a kantin magani; ana buƙatar takardar sayen magani na likita. Farashi ya bambanta daga mai samarwa. Mafi ƙarancin samfurin likita yana farashin 690 rubles, mafi tsada magungunan da aka yi daga ƙasashen waje daga 850 rubles.
Dole ne a dauki allunan zinc Rosuvastatin a baki. Don tabbatar da tasirin warkewar da ake buƙata, an haɗiye su duka, an wanke su da isasshen ƙwayar ruwa mai sauƙi. Ba shi yiwuwa a niƙa a cikin foda, tauna, fashe, da sauransu, tun da wannan ya keta mutuncin mai shigar da kayan ciki, bi da bi, yanayin yanayin ciki "yana kashe" kayan aiki.
Babu dangantakar asibiti tsakanin abinci da magani. Allunan za'a iya ɗaukar su tare da abinci, kafin abinci a kan komai a ciki, ko bayan abinci. Umarnin don amfani yana nuna cewa dole ne a haɗakar da magani tare da abincin da ya dogara da abinci masu ƙarancin cholesterol.
An tsara Rosulip don masu ciwon sukari lokacin da bincike na cholesterol ya nuna sakamakon fiye da 3 mmol a kowace lita. Lokacin zabar, dole ne a la'akari da matakin ƙimar mai haƙuri da ke fama da ciwon sukari.
Tsarin magani na gargajiya:
- Aikin warkewa yana farawa ne da karancin magani na 5-10 MG. Idan cholesterol har yanzu yana da girma bayan makonni 4, to, ana ƙaruwa sashi, Rosulip 20 mg za'a iya tsara shi.
- Bayan 4-mako magani, marasa lafiya da wani hereditary nau'i na hypercholesterolemia waɗanda suke a cikin hadarin pathologies na zuciya da jijiyoyin jini ana wajabta 40 MG kowace rana.
- An wajabta tsofaffi masu ciwon sukari guda 5 na magani a kowace rana. Bayan haka, sashi ba ya ƙaru saboda ƙuntatawa na shekaru.
- Idan mai haƙuri ya sami rauni game da aiki na dan adam mai matsakaici (creatinine har zuwa 60 ml), tarihin tsinkayewa ga myopathy kuma ga marasa lafiya na Asiya, farawa shine 5 MG; 20-40 MG ba za a taɓa ayyana su ba.
Lokacin da jiyya tare da Rosulip don ciwon sukari ba su taimaka don rage LDL da triglycerides ba, an haɗa ƙarin magunguna a cikin tsarin kulawa - nicotinic acid, kuɗi daga ƙungiyar fibrate.
Increaseara yawan magunguna na Rosulip bayan tiyata ta mako 4 ana aiwatar da ita ne kawai bayan saka idanu akan alamu na mai mai.
Contraindications da sakamako masu illa
A cikin yanayi da yawa, ba za ku iya amfani da miyagun ƙwayoyi don rage cholesterol ba, saboda yana da contraindications na likita. Wani magani kuma an wajabta shi idan mai haƙuri ya kafa ko zargin rashin isasshen abin ga mai aiki ko wasu abubuwan da ke cikin miyagun ƙwayoyi.
An ba da shawarar yin amfani da tushen asalin aiki na cututtukan hanta, wanda ke tattare da haɓaka mai ɗorewa a cikin ayyukan ƙwayoyin magani; tare da mummunan rauni na kodan (keɓantar da keɓaɓɓen ƙasa da mil 30 a lokaci ɗaya).
Kada a rubuta wa yara underan ƙasa da shekara 18 da ke fama da ciwon sukari. Ba zai yiwu ba tare da cutar sankarar bargo da kuma haifar da rikice-rikice na myotoxic, ƙwayar glucu-galactose malabsorption, rashi lactase.
Sanya tare da taka tsan-tsan a hotunan masu zuwa na asibiti:
- Yiwuwar haɗarin cutar myopathy, lalacewa aiki na renal;
- Pathology na hanta;
- Sepsis;
- Hawan jini
- Hypothyroidism
Ana ba da shawara a hankali ga marasa lafiya waɗanda ke da tarihin dogara da barasa. Jiyya na iya haifar da mummunan sakamako. A yawancin zane-zane, ana lura da sakamako masu illa na yanayin haske da wucewa da sauri.
Yin amfani da miyagun ƙwayoyi Rosulip na iya tsokani:
- Cutar Angioneurotic (da wuya).
- Ciwon kai, tsananin farin ciki (sau da yawa), rage yawan damuwa, matsalolin ƙwaƙwalwa (da wuya).
- Rushewar narkewar hanji, zawo / maƙarƙashiya, tashin zuciya, jin zafi a cikin yankin epigastric (sau da yawa). Activityara ayyukan enzymes na hanta, haɓakar matsanancin ƙwayar cutar ta hanji (ba da jimawa ba). Cutar jaundice, mai saurin kamuwa da cuta (mai saurin zuwa).
- A cikin masu ciwon sukari, a matsayin sakamako na gefe, ana lura da itching na fata, urticaria, rashes daban-daban suna bayyana a jiki.
- Myalgia (sau da yawa).
- Tari mara amfani, gajeriyar numfashi, wahalar numfashi (kamar wuya).
A lokacin jiyya, masu ciwon sukari suna buƙatar kulawa da sukari na jini koyaushe, tun da wani lokacin Rosulip yana tsokanar hawa da sauka a cikin glycemia.
Analogs da sake dubawa
Reviews on the miyagun ƙwayoyi kaɗan. Masu ciwon sukari da ke shan maganin sun lura da fa'idarsa tare da cin abinci. Har ila yau, yana da amfani sosai, tunda ya isa ya sha sau ɗaya a rana, ba tare da cin abincin ba.
Tsarin analogue na miyagun ƙwayoyi Rosulip - Rosart. Abun da ke ciki ya ƙunshi abu mai aiki ɗaya. Sashi nau'i na sakin - Allunan a cikin sashi na 5-10-20-40 mg. Ta kasance ta rukuni na statins, ana amfani dashi don kula da babban cholesterol da yanayin cututtukan da ke hade da haɓaka jini LDL. An ba da shawarar azaman prophylaxis na cututtuka na tsarin zuciya.
Rosart fara shan tare da 5 MG. Idan ya cancanta, ana ƙaruwa da sashi zuwa 10 milligrams, ana ƙayyade tsawon lokacin aikin magani daban-daban - gwargwadon matakin LDL a cikin jinin marasa lafiya. An tsara masu ciwon sukari a hankali.
Contraindications don amfani:
- Lokacin haihuwar yaro, lactation;
- Mataki na wuce gona da iri na hanta pathologies;
- Rashin lafiyar hankali;
- Tsarin yara;
- Shekarun yara har zuwa shekaru 18;
- Paarancin aiki na haya.
Rosucard wakili ne na rage kiba. Tasirin miyagun ƙwayoyi ya kasance ne ta hanyar ƙayyadadden adadin kayan aiki. Ba kamar Rosulip ba, yana da ƙarancin contraindications. Wadannan sun hada da daukar ciki, lactation, myopathy, cutar koda / cutar hanta, rashin jituwa na kwayoyin. Ba a sanya wa mata masu haihuwa haihuwa dangane da tushen tsarin yara. An tsara maganin a hankali don maganin giya, cututtukan cututtukan cututtukan fata da kuma haɗuwa tare da fibrates.
Kuna iya haɓaka jerin analogues tare da magunguna - Klivas, Rosuvastatin Sandoz, Akorta, Atomax, Simvastol da sauran kwayoyi. Tare da haɓakar halayen masu illa, likita ya zaɓi wanda zai maye gurbin, an ƙayyade sashi gwargwadon matakin farko na cholesterol, ba za ku iya ba da magani ba. Tasirin warkewa yana faruwa ne kawai tare da tsarin abinci.
Ana ba da bayani game da gumaka a cikin bidiyon a cikin wannan labarin.