Yawancin allunan haila suna taimakawa sosai wajen cire yawan suga a cikin jinin masu ciwon suga. Acarbose, aji na α-glucosidase inhibitors, yana aiki a matakin farko. Yana hana fashewar hadaddun carbohydrates shiga cikin hanjin abinci tare da shi, hakan yana rage jinkirin shigar glucose a cikin jini.
Acarbose yana aiki ne kawai a cikin gida, baya tasiri akan aikin insulin da aikin hanta, baya bada gudummawa ga hypoglycemia. Abun takaici, wannan kayan bashi da lafiya kamar yadda ake tsammani. Sakamakon sakamako masu illa mara kyau da aka bayyana a cikin umarnin, ana ɗaukar acarbose magani ne mai kiyayewa. An tsara shi ko dai tare da rashin ingancin wasu kwayoyi, ko tare da kuskuren akai-akai a cikin abincin.
Menene acarbose kuma yaya yake aiki
Abubuwan carbohydrates a cikin abincinmu sune mafi yawancin hadaddun. Da zaran cikin narkewar abinci, ana sanya su cikin ruwa ta hanyar enzymes na musamman - glycosidases, bayan su sun yanke zuwa monosaccharides. Sauki mai sauƙi, bi da bi, ya shiga cikin mucosa na hanji ya shiga cikin jini.
Acarbose a cikin tsarinsa shine pseudosaccharide wanda aka samo ta hanyar ilimin halittu. Yana gasa tare da sugars daga abinci a cikin hanji na babba: yana ɗaure wa enzymes, yana hana su ikon ɗan lokaci su rushe carbohydrates. Sakamakon wannan, acarbose yana rage jinkirin gudanawar glucose a cikin jini. Mafi yawan saukakke kuma mafi daidaituwa a jiki ya shiga cikin tasoshin, da yake yakamata ayi cire shi daga gare su cikin kyallen. Glycemia ya zama ƙasa, sauyawarsa bayan an rage abinci.
Tabbatar Acarbose Tasirin:
Ciwon sukari da hauhawar jini zai zama abin da ya wuce
- Normalization na sukari -95%
- Cirewa kan jijiyoyin mara wuya - 70%
- Cire zuciyar mai karfin zuciya -90%
- Rabu da cutar hawan jini - 92%
- Increasearuwar kuzarin rana, inganta bacci da dare -97%
- Normalizes glycated haemoglobin, inganta diyya na ciwon sukari.
- Tare da kasancewa mai keta al'aurar haƙuri a kashi 25% rage haɗarin ciwan sukari.
- Yana hana cututtukan zuciya: an rage haɗarin ta hanyar 24% a cikin masu ciwon sukari, da 49% a cikin marasa lafiya tare da NTG.
Acarbose ya fi tasiri a cikin marasa lafiya da al'ada glycemia na yau da kullun da haɓaka bayan cin abinci. Nazarin ya nuna cewa amfani da shi na iya rage glucose mai azumi da 10%, glucose bayan cin abinci da kashi 25%, glycated haemoglobin da kashi 21%, cholesterol by 10%, triglycerides by 13%. Tare da glycemia, maida hankali kan insulin a cikin jini yana raguwa. Saboda ƙananan abun ciki na insulin da lipids a cikin marasa lafiya da ciwon sukari, juriya na insulin da haɗarin atherosclerosis, an sauƙaƙe asarar nauyi.
Anyi amfani da Acarbose a matsayin mai zubar da jini a cikin shekaru fiye da 20. A cikin Rasha, ƙwayoyi guda ɗaya kawai tare da wannan abu suna rijista - Glucobai daga kamfanin Jamus Jamus Pharma Pharma. Allunan suna da allurai 2 - 50 da 100 mg.
Alamu don amfani da miyagun ƙwayoyi
Tare da ciwon sukari, ana iya ba da maganin acarbose:
- Idan cutar ta kasance mai sauƙi, amma ba koyaushe ake bi da abincin ba, ko kuma bai isa ba don daidaita sukari.
- Baya ga Metformin, idan aka samar da insulin ɗinku cikin wadataccen adadin.
- Idan abincin ya samar da glycemia na yau da kullun, amma ana gano ƙwayar triglycerides a cikin jini.
- Marasa lafiya tare da matsanancin ƙoƙari na jiki a maimakon abubuwan da suka samo asali na sulfonylurea, saboda yawanci suna haifar da cututtukan jini.
- Tare da ilimin insulin, idan ba ya taimakawa kawar da sukari cikin hanzari bayan cin abinci.
- Don rage kashi na gajeren insulin.
Hakanan ana amfani da Glucobai don asarar nauyi, duk da gaskiyar cewa umarnin don amfani basu nuna irin wannan tasirin maganin ba.
Ba za a iya shan maganin ba a cikin waɗannan halaye masu zuwa:
| Contraindication | Dalilin ban |
| Yaran zamani | Ba a gudanar da bincike game da amincin acarbose a cikin waɗannan rukunin marasa lafiya ba. |
| Ciki, GV | |
| Cututtukan narkewa na yau da kullun, gami da waɗanda ke bayan aikin ɓacin rai. | Magungunan suna aiki a cikin hanji, don haka matsaloli tare da narkewa ko shan abubuwan gina jiki kai tsaye suna tasiri tasirin sa. |
| Cututtukan tare da haɓakar iskar gas a cikin hanji. | Rike da ƙwayar Carbohydrate a cikin narkewa na narkewa yana haifar da alamun rashin jin daɗi sosai. |
| Rashin nasara idan GFR <25. | Kashi uku na acarbose an keɓance ta cikin kodan, don haka yakamata aƙalla rabin cika ayyukansu. |
Umarnin don amfani
Yadda za a fara shan Glucobay a cikin ciwon sukari:
- Maganin farko shine 150 MG a cikin allurai uku. Wajibi ne cewa acarbose ya shiga cikin esophagus a lokaci guda kamar na carbohydrates na farko, don haka Allunan suna bugu daidai kafin abinci.
- Idan wannan adadin bai isa ya daidaita glycemia ba, an ninka kashi biyu. Don rage tsananin tasirin sakamako, kana buƙatar ba jiki 1-2 watanni don yin amfani da miyagun ƙwayoyi, sannan kawai sai ka ƙara kashi na farko.
- Matsakaicin mafi kyau shine 300 MG, ya ninka sau 3. Ga marasa lafiya da raunin glucose mai ƙaran gaske, wannan adadin shine mafi girman izini.
- Matsakaicin sashi shine 600 MG. An tsara shi a lokuta na musamman, kuma kawai idan mai ciwon sukari bashi da sakamako masu illa.
Sakamakon sakamako yayin amfani da Acarbose
| Mitar abin da ya faru,% | Wanda ba a so aiki bisa ga umarnin |
| >10 | Gas, ana iya haɗa shi da abinci mai yawa, yawan gas. Intensarfin haɓakar gas yana ƙaruwa tare da ƙara yawan acarbose da adadin carbohydrates a cikin abincin. |
| <10 | Ciwon ciki, zawo a cikin cin abincin. |
| <1 | Activityara ayyukan hanta enzymes. Wannan cin zarafin na iya ɓacewa da kan shi, saboda haka bai kamata a katse magani nan da nan ba, da farko ya isa ya sarrafa aikin hanta. |
| <0,1 | Kumburi, tashin zuciya, amai, jin zafi a cikin ciki. |
| keɓaɓɓen lokuta | Canje-canje a cikin abun da ke cikin jini, rashi platelet, toshe hanji, hepatitis. Cutar cutar mahaifa. |
Tare da yawan yawan ƙwayar acarbose, tsananin tasirin sakamako a cikin narkewa yana ƙaruwa sosai, gudawa kusan yakan faru koyaushe. Don hana rashin jin daɗi, awanni 6 masu zuwa na cin abinci ne kawai da abubuwan sha na carbohydrate. A wannan lokacin, yawancin magunguna suna sarrafawa don fita daga jiki.
Yin amfani da Glucobai na Acarbose don asarar nauyi
Lokacin ɗaukar acarbose, wasu daga cikin carbohydrates basu da lokaci don rushewa kuma an keɓe su daga jiki tare da feces, kuma an rage yawan adadin kuzari daidai gwargwado. Sun yi ƙoƙarin amfani da wannan dukiya fiye da sau ɗaya don asarar nauyi, har ma an gudanar da bincike game da tasiri na miyagun ƙwayoyi don asarar nauyi. A cikin marasa lafiya da ciwon sukari, gabatarwar acarbose a cikin tsarin kulawa yana haifar da asarar nauyi na nauyin 0.4 kg. A lokaci guda, yawan caloric da yawan lodi sun kasance iri ɗaya.
An kuma gano cewa amfani da Acarbose don asarar nauyi ya fi tasiri a hade tare da abinci da wasanni. A wannan karon, an gudanar da binciken ne cikin mutane masu lafiya. Sakamakon ya kasance mai ƙarfafawa: sama da watanni 5, marasa lafiya sun rage BMI ta 2.3, a cikin rukunin sarrafawa ba tare da acarbose ba - kawai 0.7. Likitoci suna ba da shawarar cewa wannan tasirin yana da alaƙa da sakamako na gefen maganin. Da zaran sun yi rashin nauyi tare da carbohydrates, nan da nan suna kara aiwatar da fermentation a cikin hanji, zazzabi ko zawo zai fara. Acarbose a nan yana aiki a matsayin nau'i na alamar abinci mai dacewa, kowane cin zarafin abincin yana cike da sakamako mara kyau.
Me za a iya maye gurbinsa
Glucobai bashi da cikakkiyar alamun analogues. Baya ga acarbose, ƙungiyar α-glucosidase inhibitors sun haɗa da abubuwa masu aiki kamar voglibose da miglitol. Dangane da su, an ƙirƙiri Diastabol na Jamusanci, Alumina na Baturke, Yukren Ukraine Voksid. Suna da sakamako iri ɗaya, don haka ana iya ɗayan su analogues. A cikin kantin magunguna na Rasha, babu ɗayan waɗannan magungunan da aka gabatar, wanda ya sa masu ciwon sukari na cikin gida dole ne su kame kansu zuwa Glucobai ko kuma kawo magungunan daga ƙasashen waje.
Farashi
Acarbose ba a cikin jerin Magungunan Mahimmanci da Mahimmanci, saboda haka an tilasta wa marasa lafiya da ciwon sukari su sayi Glucobay da kansu. Farashin a Rasha ya tashi daga 500 zuwa 590 rubles. don allunan 30 na 50 MG. Sashi na 100 MG shine ɗan ƙara tsada: 650-830 rubles. iri daya ne.
A matsakaici, magani zai biya 2200 rubles. tsawon wata daya. A cikin kantin magunguna na kan layi, maganin yana da rahusa, amma a yawancin su zaku biya kuɗin jirgi.
Neman Masu haƙuri
A cewar masu ciwon sukari, Glucobai magani ne "maras kyau". Ba a tilasta wa marasa lafiya kawai su bi tsarin karancin carb, amma a wasu yanayi don barin kayayyakin kiwo, tunda lactose na iya haifar da narkewar abinci. An kimanta sakamakon rage sukari na acarbose da kyau. Magungunan sun sami nasarar daidaita glucose bayan cin abinci, rage yawan canzawarsa da rana.
Binciken rasa nauyi ba su da kyakkyawan fata. Suna shan miyagun ƙwayoyi musamman hakori mai daɗi, wanda ba zai iya yin ba tare da kayan zaki ba na dogon lokaci. Suna samun waɗannan kwayoyin basu da lahani, amma masu tsada sosai. Bugu da ƙari, saboda tasirin sakamako, za a iya cin abincin carbohydrate a gida kawai, ba tare da tsoron sakamakon ba. Idan aka kwatanta da Xenical, Glucobay ya fi haƙuri, amma sakamakon sa yana da ƙasa da yawa.
