Metglib da Metglib Force - umarnin, sake dubawa game da masu ciwon sukari, masu maye

Metglib magani ne na jiki wanda ya kunshi abubuwa guda 2, glibenclamide da metformin. Wannan a halin yanzu shine mafi kyawun haɗuwa da wakilai na hypoglycemic; ana amfani dasu a duk faɗin duniya.

Ana samar da Metglib ne ta Canonfarm, kamfani da ke Moscow wanda aka san shi da ingantattun ka'idoji da tushe na zamani. Magungunan yana shafar glucose jini daga bangarorin biyu: yana raunana juriya na insulin kuma yana ƙarfafa haɓakar insulin. A cikin nau'in ciwon sukari na 2, ana iya amfani da Metglib azaman monotherapy, ko kuma za'a iya haɗa shi tare da Allunan daga wasu ƙungiyoyi da ilimin insulin.

Wanene aka wajabta maganin?

Yaduwar Metglib yana da nau'in ciwon sukari na musamman 2. Hakanan, an wajabta magunguna ba a farkon cutar ba, amma tare da ci gaba. A farkon ciwon sukari, yawancin marasa lafiya sun ba da tabbacin juriya ga insulin, kuma babu canje-canje ko ƙima a cikin ƙirar insulin. Isasshen magani a wannan matakin shine karancin abinci mai gauraye, motsa jiki, da kuma metformin. Ana buƙatar Metglib lokacin da karancin insulin. A matsakaici, wannan cuta ta bayyana shekaru 5 bayan ƙaruwa na farko a cikin sukari.

Za'a iya tsara magunguna biyu na metglib:

• idan magani na baya baya bayarwa ko ƙarshe ya samar da diyya ga masu cutar siga;
• kai tsaye bayan bayyanar cututtuka na nau'in ciwon sukari na 2, idan mai haƙuri yana da isasshen sukari mai yawa (> 11). Bayan daidaituwa na nauyi da raguwa a cikin juriya na insulin, akwai babban yiwuwar cewa sashi na Metglib zai zama za'a rage ko ma canza zuwa Metformin gaba ɗaya;
• idan gwaje-gwaje na C-peptide ko insulin sun kasance ƙasa da al'ada, ba tare da la'akari da tsawon ciwon sukari ba;
• don sauƙin amfani, masu ciwon sukari waɗanda ke shan kwayoyi biyu, glibenclamide da metformin. Shan Metglib yana ba ku damar rage adadin allunan. A cewar masu ciwon sukari, wannan yana rage haɗarin manta da shan maganin.

Aikin magunguna

Kyakkyawan tasirin sukari na Metglib ya samo asali ne sakamakon kasancewar abubuwa guda biyu a cikin abubuwanda suka kasance:

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

1. Metformin - Mashahurin shugaba a gwagwarmayar jure insulin. Hakanan yana rage samarda glucose a cikin jiki, jinkirta shan shi a cikin narkewar abinci, yana inganta nauyi, kuma yana daidaita hanyoyin samarda jini. Magungunan suna aiki a waje da ƙwayar cuta, saboda haka yana da cikakkiyar lafiya a gareta. Wasu marasa lafiya da masu ciwon sukari mellitus metformin ba su da haƙuri, tare da ciwanta na yawan narkewa kamar cuta, tashin zuciya, zawo. Bayan haka, wani magani wanda yake daidai yake har yanzu bai wanzu ba, saboda haka, an wajabta metformin don kusan dukkanin masu ciwon sukari.
2. Glibenclamide - wani ƙwaƙƙwaran ƙwayar sukari mai ƙarfi wanda ke ƙarfafa samar da ƙarin insulin, mai samo asali na sulfonylurea (PSM). Yana ɗaure wa masu karɓa na beta-cell na dogon lokaci, saboda haka yana iya haifar da matsanancin rashin ƙarfi na hypoglycemia. Haka kuma, an dauki mafi yawancin magungunan ƙwayar cuta daga ƙungiyar sulfonylurea. Tasirin mummunar kwayar beta ya fi wanda aka ambata na zamanin analogues - glimepiride da gyaran glyclazide (MV Gliclazide). A cewar likitoci, masu ciwon sukari da ke shan glibenclamide suna gab da fara aikin insulin na shekaru da yawa. A mafi yawan lokuta, ana iya samun raguwar makamancin wannan a cikin hanyoyin aminci: PSM mai sauƙi da gliptins (Galvus, Januvia).

Pharmacokinetics

Fasali na sha da fitarwar Metglib, bayanan da aka karɓa daga umarnin don amfani:

Dangane da sake dubawa, sakamakon Metglib yana farawa a kan matsakaicin 2 sa'o'i bayan lokacin gudanarwa. Idan kun sha miyagun ƙwayoyi a lokaci guda a matsayin abinci, zai taimaka don cire sukari nan da nan yana shiga tasoshin jini yayin lalacewar ƙwayoyin carbohydrates jinkirin. Babban matakin ya sauka akan awoyi 4. A wannan lokacin, haɗarin hypoglycemia yana da girma musamman. Don hana shi, ya zama dole mafi girman aikin ya hadu da abun ciye-ciye.

Tunda yake hanin Metglib hanta ne kuma hanta suka fito, dole ne a kula da lafiyar wadannan gabobin. Tare da tsari mai rikitarwa na cire miyagun ƙwayoyi daga jikin mutum, mai haƙuri zai sha wahala matsanancin rashin ƙarfi na tsawan tsoka.

Sashi

Akwai magungunan a cikin nau'ikan 2. Metglib na yau da kullun yana da sashi na 400 + 2.5: metformin 400 a ciki, glibenclamide 2.5 MG. Ga masu ciwon sukari tare da rikice-rikice na nau'in 2 da juriya na insulin mai ƙarfi (motsi mara nauyi, nauyi mai yawa), wannan rabo ba shi da kyau. A gare su, an saki Metglib Force tare da babban abun ciki na metformin - 500 + 2.5. Masu ciwon sukari ba tare da wuce kima da yawa ba kuma karancin insulin sun fi dacewa da karfin Metglib 500 + 5.

An zaɓi mafi kyawun ƙwayar likita ta hanyar likita, la'akari da ƙwayar cutar glycemia da yanayin lafiyar mai haƙuri. Don kauce wa halayen sakamako na metformin, ƙwayar Metglib a hankali yana ƙaruwa, yana ba jiki lokaci don yin amfani da sabon yanayi.

Yadda za a fara shan Metglib:

1. Farawa kashi - 1 kwamfutar hannu. Garfin Metglib ko ƙarfin Metglib, don marasa lafiya tsofaffi - 500 + 2.5. Suna shan shi da safe.
2. Idan mara lafiya a baya ya sha maganin metformin da glibenclamide daban, kashi na Metglib bai kamata ya fi wanda ya gabata ba.
3. Idan miyagun ƙwayoyi ba su ba da matakin ƙima na glycemia ba, to ana iya ƙara yawan ƙwayar ta. An ba da damar kara yawan kwayoyin cutar a farkon mako 2. Ana iya ƙara Metforminum 500 MG, glibenclamide - har zuwa 5 MG.
4. Matsakaicin adadin Metglib 400 + 2.5 da Metglib Force 500 + 2.5 shine Allunan 6, don Metglib Force 500 + 5 - 4 inji mai kwakwalwa.
5. Ga tsofaffi marasa lafiya da masu ciwon sukari tare da cutar koda, kafin fara magani, umarnin ya ba da shawarar yin gwaje-gwaje don kimanta aikin koda. Idan akwai alamun canje-canje na farko, kashi na Metglib ya kamata a rage. Idan GFR kasa da 60, an haramta amfani da maganin.

Yadda ake ɗaukar Metglib

Metglib sha a lokaci guda kamar abinci. Magungunan yana da buƙatu na musamman don haɗarin samfuran. A cikin ciwon sukari na mellitus, carbohydrates yakamata ya kasance a cikin kowane abinci, sashin da ya fi dacewa ya kamata ya sami ƙananan glycemic index.

Tare da karuwa da yawan allunan, sun kasu kashi biyu (safe, maraice), sannan kuma zuwa allurai 3.

Jerin sakamako masu illa

Jerin sakamakon da ba a ke so wanda zai iya haifar da shan Metglib:

Mafi yawan tasirin sakamako na Metglib ana kiranta hypoglycemia. Abunda ya faru ya dogara ne akan ayyukan mai haƙuri da ciwon sukari, don haka haɗarinsa bashi yiwuwa a lissafa. Don hana saukad da sukari, kuna buƙatar cin carbohydrates a ko'ina cikin rana, kada ku tsallake abinci, ku rama nauyin abinci na carbohydrate na dogon lokaci, kuna iya buƙatar kayan ciye-ciye a daidai lokacin azuzuwan. Idan waɗannan matakan ba su taimaka ba, zai fi kyau maye gurbin Metglib da magungunan da ba su da kyau.

Contraindications zuwa jiyya

Koyarwar ta hana shan Metglib don kamuwa da cutar siga a cikin waɗannan lambobin:

• ketoacidosis na kowane tsananin;
• gazawar renal ko babban haɗarinsa;
• cututtukan da ke haifar da hypoxia na nama, gami da na kullum;
• nau'in ciwon sukari na 1;
• m yanayi na bukatar insulin na wucin gadi;
• rashin lafiyan kowane bangare na Metglib;
• karancin abinci mai gina jiki (<1000 kcal);
• ciki, hepatitis B;
• magani miconazole;
• tarihin lactic acidosis;
• shekarun yara.

Saboda haɗarin haɗari na lactic acidosis, umarnin ba ya ba da shawarar shan Metglib ga masu ciwon sukari na 2 masu shekaru fiye da 60 waɗanda ke fuskantar gwajin motsa jiki a kai a kai.

Yadda za a maye gurbin Metglib

Ana samar da analogs na Metglib duka a Rasha da kuma kasashen waje. Magungunan asali ana ɗauka su zama Glybomet na Jamus wanda Berlin-Chemie ke samarwa, farashinsa shine 280-370 rubles. don 40 Allunan 400 + 2.5.

Cikakkun bayanan analogues:

Idan babu haɗin haɗin glibenclamide tare da metformin a cikin kantin magani, zaku iya siyan su daban, misali, Maninil da Glyukofazh.

Kudin da aka kiyasta

Farashin kayan haɗi na allunan 40 kusan 200 rubles. Allunan 30 na Metglib Force, ba tare da la'akari da sashi ba, ana iya siyan su don 150-170 rubles. Duk analogues da aka yi a Rasha suna da kusan farashin guda.

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