Gluconorm magani ne mai arha, mai tasiri, yayi nazari sosai, amma ba koyaushe bane mai lafiya. An wajabta shi don masu ciwon sukari nau'in 2 don runtse glucose jini. Abubuwa biyu suna ba da tasirin rage sukari - glibenclamide da metformin. Dangane da bincike, hadewar waɗannan magungunan na iya ƙara rage haemoglobin glycated da 1% idan aka kwatanta da ɗayansu. Ga yawancin masu ciwon sukari, wannan kyakkyawan sakamako ne mai kyau, wanda ke ba da damar rama ga masu ciwon sukari, sabili da haka, don guje wa rikice-rikice na ƙarshensa.
Babban koma-bayan Gluconorm shine haɗarin hauhawar jini, saboda haka suna ƙoƙarin kada su sanya magunguna ga marasa lafiya da saurin saukad da saurin sukari.
Alamu don alƙawarin gluconorm
A yawancin marasa lafiya da ke fama da cutar sankara, ƙwaƙwalwa guda ɗaya ba ta iya tsayar da glucose na al'ada, don haka likitoci galibi suna haɗuwa da magani. Nunin don alƙawarinsa akwai gemoclobin glycated sama da 6.5-7%. Mafi yawan la'akari da haɗuwa da haɗuwa da metformin tare da abubuwan da suka samo asali na sulfonylurea (PSM), gliptins da incetin mimetics. Duk waɗannan haɗuwa suna tasiri duka juriya na insulin da kuma yawan samar da insulin, sabili da haka suna samar da sakamako mafi kyau.
Haɗin metformin + sulfonylurea shine mafi yawan gama gari. Abubuwa basa iya hulɗa da junan ku, kada ku rage tasiri. Glibenclamide shine mafi iko da kuma nazarin dukkan PSM. Yana da ƙananan farashi kuma ana siyar dashi a cikin kowane kantin magani, sabili da haka, a hade tare da metformin, an tsara glibenclamide fiye da sauran kwayoyi. Don sauƙaƙan amfani, an ƙirƙiri allunan abubuwa guda biyu tare da waɗannan abubuwan aiki guda biyu - Gluconorm da analogues.
Dangane da umarnin, ana amfani da Gluconorm na musamman ga masu ciwon sukari na 2, idan gyaran abinci, wasanni, da metformin ba su haifar da digo a cikin glucose don ƙima ƙima. Yawan maganin metformin ba zai zama mafi ƙarancin inganci ba (2000 mg) ko kuma mai ciwon sukari ya jure da shi. Hakanan, ana iya ɗaukar gluconorm ta hanyar marasa lafiyar da suka sha glibenclamide a baya kuma metformin daban.
Ciwon sukari da hauhawar jini zai zama abin da ya wuce
- Normalization na sukari -95%
- Cirewa kan jijiyoyin mara wuya - 70%
- Cire zuciyar mai karfin zuciya -90%
- Rabu da cutar hawan jini - 92%
- Increasearuwar kuzarin rana, inganta bacci da dare -97%
An gano bincike: ƙarancin allunan da mai haƙuri ke ɗauka kowace rana, da ƙari yana da sha'awar bi duk magungunan likita, wanda ke nufin cewa mafi girman tasirin magani. Wato, shan Gluconorm maimakon allunan guda biyu ƙaramin mataki ne don mafi kyawun diyya ga masu ciwon sukari.
Bugu da kari, haɓaka sau biyu a cikin matakan allunan sukari masu rage sukari ba su bayar da rage guda ɗaya na sukari ba. Wato, magunguna guda biyu a cikin ƙaramin aiki zasuyi aiki sosai kuma suna ba da ƙananan sakamako masu illa fiye da ɗaya magani a cikin iyakar adadin.
Abun da kuma maganin yake amfani dashi
Gluconorm an samar da kamfanin nan na Rasha tare da Pharmstandard tare da haɗin gwiwar Indian Biopharm na Indiya. Ana amfani da miyagun ƙwayoyi a cikin sigogi 2:
- Ana yin allunan gluconorm a Indiya, an shirya su a Rasha. Magungunan suna da maganin gargajiya na 2.5-400, wato, kowane kwamfutar hannu na metformin ya ƙunshi 400 mg, glibenclamide 2.5 MG.
- Ana samar da allunan gluconorm Plus a cikin Russia daga kayan magani wanda aka saya a Indiya da China. Suna da sashi guda 2: 2.5-500 ga masu ciwon sukari tare da juriya na insulin da 5-500 ga marasa lafiya ba tare da wuce kima ba, amma tare da nuna karancin insulin.
Godiya ga zaɓuɓɓukan sashi daban-daban, zaku iya zaɓar madaidaiciyar rabo ga kowane mai haƙuri da ciwon sukari na 2.
Bari muyi la’akari dalla-dalla yadda abubuwan da ke cikin magungunan Gluconorm ke aiki. Metformin yana rage duka postprandial da azumi glycemia wanda yafi yawa saboda raguwar juriya na insulin. Glucose yana barin tasoshin da sauri kamar yadda ƙwayar jijiyar nama zuwa insulin ke ƙaruwa. Metformin shima yana rage samuwar glucose a jiki daga abubuwanda basa amfani da shi, yana rage jinkirin shiga cikin jini daga narkewar abinci.
Ga masu ciwon sukari, ƙarin kaddarorin metformin waɗanda basu da alaƙa da raguwa a cikin glycemia suma suna da matukar muhimmanci. Magani ya hana haɓakar angiopathy ta hanyar inganta lipids na jini, inganta abinci mai ƙoshin nama. A cewar wasu rahotanni, metformin yana da ikon hana bayyanar neoplasms. A cewar masu haƙuri, yana rage yawan ci, yana taimakawa ci gaba da nauyin al'ada, yana ƙarfafa nauyi, da ƙara haɓaka abincin.
Glibenclamide shine PSM 2 tsara. Yana aiki kai tsaye akan sel na fitsari: yana rage ƙarshen ƙimar hankalinsu ga matakan glucose na jini, don haka yana haɓaka samar da insulin. Har ila yau, Glibenclamide yana haɓaka glycogenogenesis, aiwatar da adanar glucose a cikin tsokoki da hanta. Ba kamar metformin ba, wannan magani na iya haifar da hypoglycemia, mafi tsananin ƙarfi fiye da sauran wakilan ƙungiyar PSM - glimepiride da glyclazide. Ana daukar Glibenclamide mafi ƙarfi, amma kuma mafi hatsarin PSM. Ba'a ba da shawarar ga masu ciwon sukari ba tare da haɗarin hypoglycemia.
Yadda ake shan Maganin Gluconorm
Mafi yawan tasirin sakamako na metformin shine narkewa, glibenclamide - hypoglycemia. Kuna iya rage haɗarin mummunan sakamako na jiyya tare da gluconorm, shan kwayoyi a lokaci guda kamar abinci kuma sannu a hankali suna kara kashi, farawa da mafi ƙarancin.
Sashi na miyagun ƙwayoyi Gluconorm bisa ga umarnin:
Fasali na liyafar | Gluconorm | Karin Gluconorm | |
2,5-500 | 5-500 | ||
Fara amfani, shafin. | 1-2 | 1 | 1 |
Yawan iyakance, shafin. | 5 | 6 | 4 |
Oda na kara sashi | Muna haɓaka kashi ta hanyar kwamfutar hannu 1 a cikin kowane kwanaki 3 idan mai haƙuri ya samu nasarar ɗaukar metformin a baya. Idan ba a ba da maganin metformin ga mai ciwon sukari ba, ko kuma bai yi haƙuri da shi da kyau ba, ƙara kwamfutar hannu ta biyu ba kafin makonni 2 ba. | ||
Untatawa ga masu ciwon sukari da cutar koda da hanta | Don cire gluconorm daga jiki, kyakkyawan hanta da aikin koda ya zama dole. Game da ƙarancin waɗannan gabobin na ƙananan digiri, koyarwar suna ba da shawarar iyakance ga mafi ƙarancin amfani. Farawa tare da matsakaici na kasawa, an haramta maganin. | ||
Yanayin aikace-aikace | Sha 1 kwamfutar hannu a karin kumallo, 2 ko 4 a karin kumallo da abincin dare. 3, 5, 6 shafin. ya kasu kashi uku. |
Tare da juriya na insulin mai ƙarfi, wanda shine halayen mutane masu kiba tare da ciwon sukari, ana iya tsara ƙarin metformin. Yawancin lokaci a wannan yanayin suna shan shi kafin zuwa gado. Mafi kyawun kashi na yau da kullun metformin ana ɗauka shine 2000 MG, matsakaicin - 3000 MG. Furtherarin ƙaruwa a sashi yana da haɗari tare da lactic acidosis.
Tare da rashin carbohydrates a cikin abinci, Gluconorm yana haifar da hypoglycemia. Don hana shi, allunan sun bugu tare da manyan abinci. Dole ne samfura su ƙunshi carbohydrates, mafi yawan jinkirin. Ba za ku iya ba da damar dogon tsayi tsakanin abinci ba, saboda haka ana ba da shawarar ƙarin haƙuri. Binciken masu ciwon sukari sun nuna cewa tare da matsanancin ƙoƙarin jiki, sukari na iya faɗuwa cikin 'yan mintina. A wannan lokacin, kuna buƙatar ku mai da hankali musamman ga lafiyar ku.
Side effects da yawan abin sama da ya kamata
Abin da sakamako masu illa na iya kamuwa da mai ciwon suga yayin amfani da Gluconorm ko misalinsa:
- hypoglycemia a sakamakon PSM;
- halayen daga narkewa kamar jijiyoyin, narkewar su shine metformin. Dangane da sake dubawa, yawancin masu ciwon sukari suna haifar da gudawa da rashin safiya. Umarnin don amfani yayi kashedin cewa zafin ciki da amai suma hakan zai yiwu. Idan irin waɗannan matsalolin sun tashi, kada ku bar Gluconorm nan da nan, yawanci a cikin mako guda jiki yana dacewa da dakatar da amsawa ga miyagun ƙwayoyi kamar haka;
- take hakkin tsarin samarda jini. Yawan abubuwan da ke cikin salula a cikin jini na iya raguwa. Lokacin da aka dakatar da jiyya tare da Gluconorm, an mayar da abun da ke cikin jini;
- lactic acidosis ne mai wuya rikitar da ciwon sukari, halayyar nau'in 2. Ba tare da taimakon likita ba, yana haifar da hauhawar jini;
- rashin haƙuri ga barasa a cikin yanayin m;
- tsarin juyayi na tsakiya na iya amsawa ga amfani da gluconorm tare da ciwon kai da rauni;
- halayen rashin lafiyan suna yiwuwa, har zuwa anaphylactic.
Abubuwan da ke haifar da sakamako masu illa kamar suƙar fitsari da kuma lactic acidosis sune sakamakon hauhawar yawan ƙwayar cuta ta Gluconorm. Zai iya kasancewa:
- Kai tsaye: masu ciwon sukari sun sha fiye da yadda aka tsara.
- Kai tsaye. Hypoglycemia na iya faruwa lokacin da karancin carbohydrates a cikin abinci ko glucose ke cinyewa cikin hanzari yayin aiki na jiki da matsananciyar damuwa, halayyar dan adam da kuma ilimin halin mutum. Samuwar lactate yana ƙaruwa a cikin yanayin maye na giya, gazawar ƙwayar cuta wanda ke haifar da hypoxia, tare da raunin raunin da cututtuka.
Ayyuka don yawan zubar da jini bisa ga umarnin: hypoglycemia mai sauƙi ana dakatar da glucose ko samfura tare da babban abun ciki. Lactic acidosis da hypoglycemia, tare da raunin hankali, suna buƙatar asibiti na gaggawa.
Contraindications
Lokacin da Gluconorm don ciwon sukari baza ayi amfani dashi ba:
- tare da karuwar hankalin mai kwakwalwa zuwa abubuwan da ke jikin kwamfutar hannu. Wannan contraindication ya hada da halayen rashin lafiyan, kuma ya ayyana aiyukan da ba a so wadanda ke buƙatar dakatar da maganin;
- idan an gano nau'in 1 na ciwon sukari;
- yayin kulawa da matsanancin rikice-rikice na ciwon sukari, cututtukan cuta mai rauni da raunin da ya faru. Yanke shawara game da canji na wucin gadi zuwa maganin insulin ne wanda likitan da ke halarta ya kasance;
- tare da rauni mai girma na yara ko babban haɗarin irin wannan rashin ƙarfi;
- yayin daukar ciki da HB. Theuntatawa ta amfani da Gluconorm mai tsauri ne, tunda PSM a cikin ƙirar kwamfutar hannu na iya rushe ci gaban tayin, haifar da hauhawar jini a cikin yaro;
- yayin shan magunan antifungal. Haɗin Gluconorm tare da miconazole ko fluconazole yana da ɓarna tare da mummunan cutar hypoglycemia. Jerin magungunan da ke shafar aikin Gluconorm an nuna su a cikin umarnin don amfani;
- idan mai ciwon sukari ya riga ya dandana lactic acidosis ko yana da haɗarin bunkasa shi.
Analogs da wasu abubuwa
Ma’aikata | Mai masana'anta | Alamar kasuwanci |
Cikakken analogues na gluconorm | Canonpharma | Metglib |
Berlin-Chemie, dakin gwaje-gwaje na Guidotti | Glibomet | |
Gluconorm Plus Analogs | Pharmynthesis | Glibenfage |
Canopharma | Forcearfin Metglib | |
Merck Sante | Glucovans | |
Mai karfi | Bagomet Plus | |
Shirye-shiryen Metformin | Vertex, Gideon Richter, Medisorb, IzvarinoFarma, da sauransu. | Metformin |
Pharmynthesis | Merifatin | |
Merk | Glucophage | |
Shirye-shiryen Glibenclamide | Pharmynthesis | Statiglin |
Pharmstandard, Atoll, Moskhimpharmpreparaty, da sauransu. | Glibenclamide | |
Barcelona Chemie | Maninil | |
Magunguna guda biyu: metformin + PSM | Sanofi | Amaryl, a matsayin wani ɓangare na PSM glimepiride |
Akrikhin | Glimecomb, ya ƙunshi PSM Gliclazide |
Cikakken analogues, kazalika da metformin da glibenclamide daban, zasu iya zama masu maye cikin kwanciyar hankali iri daya kamar na Gluconorm. Idan kuna shirin canzawa zuwa jiyya tare da wani tsararren maganin sulfonylurea, Dole ne a sake zaɓin kashi. Likitocin sun ba da shawarar sauya daga Gluconorm zuwa Amaryl ko Glimecomb ga masu ciwon sukari tare da rikicewar cututtukan carbohydrate na 2, wanda yawanci ke fama da cututtukan jini.
Dangane da sake dubawa, tasiri na Gluconorm da analogues yana kusa, amma masu ciwon sukari sun fi son Glybomet na Jamus, suna la'akari da shi a matsayin magani mafi inganci.
Dokokin ajiya da farashi
Gluconorm yana da tasiri har tsawon shekaru 3 daga ranar samarwa. An ba da izinin Gluconorm Plus don adanawa sama da shekaru 2. Koyarwar ba ta ƙunshi buƙatu na musamman don yanayin ajiya, ya isa a lura da tsarin yanayin zafi wanda bai wuce digiri 25 ba.
Masu ciwon sukari na Rasha na iya karɓar magunguna biyu gwargwadon rubutaccen magani da babban likitan likitanci ko kuma endocrinologist ya tsara. Sayayyar mai zaman kanta za ta kashe mara tsada: farashin fakitin 40 allunan Gluconorm kusan 230 rubles ne, Gluconorm Plus farashin daga 155 zuwa 215 rubles. na allunan 30. Don kwatantawa, farashin Glibomet na asali ya kusan 320 rubles.