A cikin 1 ml. Insulin Humulin ya ƙunshi IU 100 na insulin na ɗan adam. Abubuwan da suke aiki sune insulin 30% mai narkewa da isofan insulin na 70%.
Kamar yadda aka yi amfani da kayan taimako:
- distacacic manic,
- phenol
- sodium hydrogen phosphate heptahydrate,
- hydrochloric acid,
- glycerol
- sinadarin zinc
- furotin sulfate,
- sodium hydroxide
- ruwa.
Fom ɗin saki
Halin insulin Humulin M3 ana samun insulin a cikin nau'ikan dakatarwa don gudanarwa a cikin kwalaben 10 ml, kazalika a cikin kwantena 1.5 da 3, kwantena a cikin kwalaye na guda 5. An tsara katako don amfani dashi a cikin sirinji na Humapen da BD-Pen.
Magungunan yana da tasirin hypoglycemic.
Humulin M3 yana nufin magungunan sake haɗuwa da kwayar halitta na DNA, insulin shine dakatarwar allura biyu tare da matsakaicin tsawon lokacin aiki.
Bayan gabatarwar miyagun ƙwayoyi, ingancin magunguna yana faruwa bayan minti 30-60. Matsakaicin sakamako yana gudana daga 2 zuwa 12 hours, jimlar tsawon tasirin shine 18-24 hours.
Ayyukan insulin na Humulin na iya bambanta dangane da wurin gudanar da maganin, daidaitaccen adadin da aka zaɓa, aikin jiki na mai haƙuri, rage cin abinci da sauran abubuwan.
Babban tasirin Humulin M3 yana da alaƙa da tsarin canza hanyoyin glucose. Insulin kuma yana da tasirin anabolic. A kusan dukkanin kyallen takarda (banda kwakwalwa) da tsokoki, insulin yana motsa motsi na glucose da amino acid, kuma yana haifar da haɓakar anabolism na furotin.
Insulin yana taimakawa canza glucose zuwa glycogen, kuma yana taimakawa juya sukari mai yawa ya zama fats kuma yana hana gluconeogenesis.
Alamu don amfani da sakamako masu illa
- Ciwon sukari mellitus, wanda ake ba da shawarar insulin.
- Cutar kwayar cutar mahaifa (ciwon sukari na mata masu juna biyu).
Side effects
- Kafaffen hypoglycemia.
- Rashin hankali.
Sau da yawa yayin jiyya tare da shirye-shiryen insulin, ciki har da Humulin M3, ana lura da ci gaban hypoglycemia. Idan yana da mummunan tsari, zai iya tsokanar rashin lafiyar jiki (rashin damuwa da asarar hankali) har ma ya kai ga mutuwar mai haƙuri.
A cikin wasu marasa lafiya, halayen rashin lafiyan na iya faruwa, wanda ya bayyana ta amalar fata, kumburi da redness a wurin allurar. Yawanci, waɗannan alamun suna ɓacewa da kansu a cikin 'yan kwanaki ko makonni bayan fara magani.
Wasu lokuta wannan bashi da alaƙa da amfani da miyagun ƙwayoyi da kanta, amma sakamakon rinjayar abubuwan ne na waje ko allurar da ba ta dace ba.
Akwai alamun rashin lafiyan yanayin dabi'a. Suna faruwa sau da yawa ba sau da yawa, amma sun fi muni. Tare da irin wannan halayen, abubuwan da ke faruwa suna faruwa:
- wahalar numfashi
- yawan itching;
- bugun zuciya;
- sauke cikin karfin jini;
- karancin numfashi
- wuce kima gumi.
A cikin mafi yawan lokuta masu rauni, rashin lafiyan mutum na iya haifar da barazana ga rayuwar mai haƙuri kuma yana buƙatar kulawar likita ta gaggawa. Wani lokaci ana buƙatar maye gurbin insulin ko buƙatar bacci.
Lokacin amfani da insulin na dabba, juriya, rashin hankali ga miyagun ƙwayoyi, ko lipodystrophy na iya haɓaka. Tare da nadin insulin Humulin M3, yuwuwar irin waɗannan sakamakon kusan ba komai bane.
Umarnin don amfani
Ba a yarda da insulin na Humulin M3 ba a cikin sarrafawa.
Lokacin rubuta insulin, likita kawai zai iya zaɓin kashi da yanayin gudanarwa. Ana yin wannan ne daban-daban ga kowane haƙuri, dangane da matakin glycemia a jikinsa. Humulin M3 an yi nufin shi ne don gudanar da subcutaneous, amma kuma ana iya sarrafa shi intramuscularly, insulin ya yarda da wannan. A kowane hali, mai ciwon sukari dole ne ya san yadda ake yin insulin.
Bayan haka, ana allurar da maganin a ciki, cinya, kafada ko gindi. A wuri guda za'a iya ba da allurar fiye da sau ɗaya a wata. Yayin aikin, ya zama dole don amfani da na'urorin allura daidai, don hana allura shiga cikin jijiyoyin jini, ba don tausa wurin allurar ba bayan allurar.
Humulin M3 wani shiri ne wanda aka shirya dashi wanda ya kunshi Humulin NPH da Humulin Regular. Wannan ya sa ya yiwu ba shirya maganin kafin gudanarwa ga mai haƙuri da kansa ba.
Don shirya insulin don allurar, murfin katako ko kabad na Humulin M3 NPH ya kamata a birgima sau 10 a cikin hannunka kuma, juyawa digiri 180, a hankali girgiza daga gefe zuwa gefe. Wannan ya kamata a yi har sai dakatarwar ta zama kamar madara ko kuma ta zama kamar ruwa mai ruwa mai girgije.
Ba da shawarar yin amfani da insulin cikin NPH da sauri, saboda wannan na iya haifar da bayyanar kumfa kuma ya tsoma baki tare da ainihin sashi. Kada ku yi amfani da magani tare da laka ko flakes da aka kafa bayan haɗuwa.
Gudanar da insulin
Don shigar da ƙwayoyi daidai, dole ne a fara aiwatar da wasu hanyoyin farko. Da farko kuna buƙatar ƙayyade wurin yin allurar, ku wanke hannuwanku da kyau kuma ku goge wannan wurin tare da zane mai tsami a cikin barasa.
Bayan haka, cire maƙarƙashin kariya daga allura mai siririn, gyara fata (cire shi ko toshe shi), saka allura kuma yi allura. Bayan haka ya kamata a cire allura kuma har da daƙiƙu kaɗan, ba tare da shafawa ba, danna wurin allura tare da adiko na goge baki. Bayan haka, tare da taimakon murfin kariya na waje, kuna buƙatar kwance allura, cire shi kuma sanya murfin baya a alƙalin sirinji.
Baza ku iya amfani da almara guda ba sau biyu. Ana amfani da vial ko kabad har sai komai ya lalace, sannan a jefar da shi. Alkalamiin sikelin an yi shi ne don amfanin mutum kawai.
Yawan damuwa
Humulin M3 NPH, kamar sauran magunguna a cikin wannan rukuni na kwayoyi, ba shi da ma'anar cikakkiyar ma'amala game da yawan ƙwayar cuta, tunda matakin glucose a cikin ƙwayar jini ya dogara da ma'amala tsakanin tsari tsakanin matakan glucose, insulin da sauran matakan rayuwa. Koyaya, yawan insulin da ya wuce zai iya samun mummunan tasirin.
Hypoglycemia yana haɓaka sakamakon rashin daidaituwa tsakanin abun da ke cikin insulin a cikin plasma da kuzarin kuzari da kuma abincin abinci.
Waɗannan alamu sune halayen haɓakar haihuwar jini:
- bari;
- tachycardia;
- amai
- yawan wuce haddi;
- pallor na fata;
- rawar jiki
- ciwon kai
- rikicewa.
A wasu halaye, alal misali, tare da dogon tarihin ciwon sukari mellitus ko kulawa ta kusa, alamun farawar hawan jini na iya canzawa. Za'a iya hana hauhawar jini ta hanyar shan glucose ko sukari. Wani lokaci zaku buƙaci daidaita sashin insulin, sake bitar abincin ko canza ayyukan jiki.
Yawancin hypoglycemia ana yinsa ne sau da yawa ta hanyar subcutaneous ko sarrafawar intanetus na glucagon, biye da carbohydrates. A cikin mawuyacin yanayi, a gaban rikicewar jijiyoyin zuciya, rashi ko na coma, ban da allurar glucagon, dole ne a gudanar da tattarawar glucose a cikin ciki.
A nan gaba, domin hana sake dawowa daga cututtukan jikin mutum, mai haƙuri yakamata ya ɗauki abinci mai wadataccen carbohydrates. Wani mummunan mataki na yanayin rashin lafiyar hypoglycemic yana buƙatar asibiti gaggawa.
Abun Harkokin Magunguna NPH
Tasirin Humulin M3 yana haɓaka ta amfani da maganin hana haihuwa, ethanol, abubuwan da suka dace na salicylic acid, monoamine oxidase inhibitors, sulfonamides, ACE inhibitors, angiotensin II masu karɓar tallafi, masu hana beta-blockers.
Magungunan Glucocorticoid, hormones girma, maganin hana haihuwa, danazole, hormones thyroid, thiazide diuretics, beta2-sympathomimetics suna haifar da raguwa a cikin sakamako na hypoglycemic na insulin.
Orarfafa ko, ba da shawara ba, ya raunana dogara da insulin iya yin maganin lancreotide da sauran analogues na somatostatin.
Kwayar cutar hypoglycemia ana lubricated yayin ɗaukar clonidine, reserpine da beta-blockers.
Sharuɗɗan sayarwa, ajiya
Humulin M3 NPH yana samuwa a kantin magani kawai ta takardar sayan magani.
Dole ne a adana magungunan a zazzabi na 2 zuwa 8, ba za a iya daskarewa kuma a fallasa su ga hasken rana da zafi ba.
Ana buɗe ɓoyayyen butulcin NPH a zazzabi na 15 zuwa 25 don kwanaki 28.
Amincewa da tsarin zafin jiki da ake buƙata, an adana shirin NPH na shekaru 3.
Umarni na musamman
Dakatar da rashin izini game da magani ko kuma alƙawarin da ba daidai ba (wanda yake gaskiya ne ga marasa lafiyar insulin) na iya haifar da ciwan ketoacidosis na ciwon sukari ko hyperglycemia, wanda ke haifar da haɗari ga rayuwar mai haƙuri.
A cikin wasu mutane, lokacin amfani da insulin na mutum, alamomin farawar hypoglycemia na iya bambanta da alamomin alamun insulin dabbobi, ko kuma suna da alamun bayyanannu.
Mai haƙuri ya kamata ya sani cewa idan matakin glucose na jini ya zama al'ada (alal misali, tare da maganin insulin mai zurfi), to alamomin da ke ba da shawara wanda ke gabatowa yawan jini zai iya ɓacewa.
Wadannan bayyanannun na iya zama mai rauni ko kuma bayyana daban idan mutum ya ɗauki beta-blockers ko kuma yana da mellitus na ciwon sukari na tsawon lokaci, da kuma a gaban masu ciwon suga.
Idan rashin lafiyar hyperglycemia, kamar hypoglycemia, ba a gyara ta hanyar da ta dace, wannan na iya haifar da asarar hankali, korar jini, har ma da mutuwar mai haƙuri.
Ya kamata mai haƙuri ya canza zuwa wasu shirye-shiryen insulin NPH ko nau'ikan su kawai a ƙarƙashin kulawar likita. Canza insulin zuwa magani tare da wani aiki na daban, hanyar samarwa (DNA, dabba), nau'in (alade, analog) na iya buƙatar gaggawa ko, akasin haka, ingantaccen gyaran magungunan da aka tsara.
Tare da cututtuka na kodan ko hanta, isasshen aikin ƙwaƙwalwar ƙwayar cuta, aiki mara nauyi na glandar adrenal da glandar thyroid, buƙatar haƙuri ga insulin na iya raguwa, kuma tare da matsananciyar damuwa na damuwa da wasu yanayi, akasin haka, haɓaka.
Mai haƙuri yakamata ya tuna da yiwuwar haɓakar haɓaka da ƙididdiga tare da tantance yanayin jikinsa yayin tuki.
Analogs
- Monodar (K15; K30; K50);
- Novomix 30 Flekspen;
- Ryzodeg Flextach;
- Haɗin Humalog (25; 50).
- Gensulin M (10; 20; 30; 40; 50);
- Gensulin N;
- Rinsulin NPH;
- Farmasulin H 30/70;
- Humodar B;
- Vosulin 30/70;
- Vosulin N;
- Mikstard 30 NM;
- Protafan NM;
- Humulin.
Haihuwa da lactation
Idan mace mai ciki tana fama da ciwon sukari, to yana da matukar mahimmanci a gare ta don sarrafa glycemia. A wannan lokacin, buƙatar insulin yawanci yana canzawa a lokuta daban-daban. A cikin farkon farkon, yana fadi, kuma a cikin na biyu da na uku yana ƙaruwa, don haka daidaitawa kashi na iya zama dole.
Hakanan, ana buƙatar canza canji, rage cin abinci da aikin jiki yayin lactation.
Idan wannan shirin insulin ya dace sosai ga mai haƙuri da ciwon sukari mellitus, to, sake dubawa game da Humulin M3, a matsayin mai mulkin, suna da kyau. A cewar marasa lafiya, miyagun ƙwayoyi suna da tasiri sosai kuma kusan ba shi da sakamako masu illa.
Yana da mahimmanci a tuna cewa an haramta shi sosai don sanya wa kansa insulin, ka kuma canza shi zuwa wani.
Bottleaya daga cikin kwalban Humulin M3 tare da ƙarar kuɗin 10 ml daga 500 zuwa 600 rubles, fakiti na katako guda 3 ml a cikin kewayon 1000-1200 rubles.
