Tare da cututtukan da ba su da insulin-da ke fama da ciwon sukari, ana amfani da kwayoyi masu rage sukari sau da yawa. Ana daukar Glucophage ɗayan mashahuran kwayoyi, saboda kyakkyawan aikinsa.
Ciwon sukari mellitus, kasancewa cuta ce gama gari gama gari, da farko ba ta wata hanyar bayyana kanta. A tsawon lokaci, yawan ƙwayar cutar glycemia yana haifar da shan kashi kusan dukkanin gabobin ciki. Abubuwan haɗari mafi haɗari na ciwon sukari sune retinopathy, ƙafafun sukari, nephropathy da neuropathy.
Don hana irin wannan sakamakon da ba a so, ya zama dole a bi duk ka'idodin magani, gami da amfani da allunan Glucofage na yau da kullun.
Babban bayani game da miyagun ƙwayoyi
Wannan ƙwayar cuta ce ta baki kuma tana cikin ajin biguanides, saboda yana ƙunshe da babban bangaren - metformin hydrochloride. An samar da shi a cikin magunguna daban-daban, watau 500, 850 ko 1000 mg.
Har ila yau, masana'antun suna samar da Glucophage Long - wani shiri mai kama da juna a cikin abun da ke ciki, wanda ke da tasiri sosai. Koyaya, a cikin wannan labarin zamuyi magana game da Glucofage.
Baya ga abu mai aiki, abun da ke tattare da maganin antidiabetic ya hada da abubuwa kamar magnesium stearate, povidone da opadra mai tsabta.
Tare da gudanarwar Glucofage na ciki, metformin yana shiga cikin jijiyar ciki, yana kasancewa cikakke a ciki. Matsakaicin abun ciki na sashi mai aiki yana faruwa bayan sa'o'i biyu na mulkin miyagun ƙwayoyi. Godiya ga aikin da miyagun ƙwayoyi, mutum zai iya cimma sakamako kamar haka:
- Rage sukari na jini zuwa dabi'un al'ada. A wannan yanayin, ba a lura da yanayin hypoglycemic, tun da ƙwayar ba ta tsokani samar da insulin ba.
- Responseara amsawar ƙwaƙwalwa zuwa ƙwayar da aka samar.
- Rage yawan samar da glucose na hanta ta hana glycogenolysis da gluconeogenesis.
- Jinkirta yawan sha na mama.
- Inganta tsarin haɗin glycogen da ƙarfin jigilar masu safarar glucose.
- Kwantar da hankali har ma rage nauyin jikinka. Dangane da wannan, akwai aikin shan wannan magani a cikin marasa lafiya masu lafiya waɗanda suke so su rasa nauyi. Ba su da raguwa a matakan sukari a ƙasa da matakan al'ada.
- Inganta metabolism na lipid da ƙananan cholesterol.
Abubuwan da suke aiki ana rarraba su a ko'ina cikin tsarin jikinsu kuma bai da alaƙa ga furotin a cikin jini. Magungunan ba shi da cikakken haɗin ƙarfe, amma an cire shi tare da fitsari.
Bayan sanin yadda Glucophage ke aiki, zaku iya nuna mahimman abubuwan amfani. Waɗannan sun haɗa da cututtukan da basu da insulin-insulin ƙwaƙwalwa tare da rashin ingancin abinci na musamman da kuma kiba:
- a cikin yara da matasa masu shekaru 10 da haihuwa kadai ko kuma tare da allurar insulin;
- A cikin manya masu keɓaɓɓen kashi ko tare da wasu magungunan antidiabetic.
A cikin ciwon suga, idan aka sami ƙarin dalilai na haɗarin kamuwa da ciwon sukari na 2, an kuma sanya allurar Glucofage.
Umarnin don amfani da miyagun ƙwayoyi
Ana amfani da Glucophage tare da nau'in ciwon sukari na 2 a tsanake cikin lura da yadda yake dashi da kuma duk shawarar da likita ke halarta. Lokacin sayen magani, kuna buƙatar tabbatar da dacewa da shi kuma ku san kanku da shigarwa. Idan kuna da tambayoyi masu alaƙa da amfani da maganin, zaku iya tambayar ƙwararre.
M ya ƙunshi waɗannan bayanai game da shan ƙwayoyi. A farkon jiyya, suna shan sau biyu ko sau uku 500-850 MG a rana yayin ko bayan abincin. Yana da mahimmanci a rarraba abubuwan yau da kullun sau da yawa, tunda irin waɗannan ayyukan zasu iya raunana mummunan tasirin ƙwayar. Wannan halayen yana da alaƙa da ƙari na jiki ga tasirin metformin. Saboda wannan, sau da yawa masu ciwon sukari lokacin shan Glucofage suna koka game da ƙoshin abinci, wato tashin zuciya, zawo, amai, ɗanɗano mai ƙarfe a cikin kogon baki, jin zafi a cikin ciki ko rashin jin daɗi. A cikin makonni biyu, irin waɗannan alamun sun ɓace, wanda ke nuna yiwuwar ƙara yawan sashi.
Adadin kulawa shine 1500-2000 MG kowace rana. Mafi yawan kullun an yarda da shan Glucofage sashi na 3000 MG.
Idan mai haƙuri yana buƙatar juyawa daga wasu magungunan rigakafin ƙwayar cuta zuwa shan Glucofage, da farko za ku daina amfani da wani magani.
Wani lokaci endocrinologists suna ba da shawarar yin amfani da insulin da Glucophage injections a hade tare da nau'in ciwon sukari na 2. A kashi na 500-850 MG sau biyu ko sau uku a rana, sashi na insulin an ƙaddara yin la’akari da abubuwan sukari.
Nawa Allunan Glucofage yara suke buƙatar sha? A cikin marasa lafiya matasa, fara daga shekara 10, an ba da izinin amfani da miyagun ƙwayoyi, duka daban kuma a hade tare da insulin. Sake farawa guda ɗaya na farko shine 500-850 MG, a tsawon lokaci ana iya ƙaruwa zuwa kashi biyu zuwa uku.
Yadda za a sha Glucophage tare da ciwon sukari? Yawancin lokaci ana ɗaukar shi a 1000-1800 MG kowace rana, an kasu kashi biyu.
Idan batun rashin lafiyar koda ko a cikin tsofaffi, ana daukar maganin Glucophage a karkashin kulawa ta musamman daga likitan da ke halartar. Don yin wannan, yakamata a bincika ayyukan koda a kai a kai sau 2-4 a shekara.
Ana adana kayan adana a cikin duhu duhu wurin ga yara. Tsarin zafin jiki kada ya wuce digiri 25 na Celsius. A matsayinka na mai mulkin, rayuwar shiryayye na Glucofage 500 ko 850 MG shine shekaru biyar, kuma Glucofage 1000 MG shine shekara uku.
Contraindications da yiwu cutar
Lokacin sayen Glucophage, dole ne a yi nazarin umarnin amfani dashi.
Littafin bayanin da aka haɗe yana ɗauke da takamaiman jerin abubuwan contraindications don amfanin glucophage.
Kafin rubuta wakili na maganin cututtukan ƙwayar cuta, likita ya kamata ya lura da duk abubuwan da ke tattare da cututtukan masu ciwon sukari don guje wa mummunan sakamako. Don haka, an haramta amfani da Allunan tare da:
- Yin haihuwar jariri ko lokacin shayarwa.
- Hypersensitivity ga babban bangaren da ƙarin abubuwa.
- Precoma na ciwon sukari, coma, ketoacidosis, kazalika da lactic acidosis.
- Rashin ƙarfi, raunin aiki na kasa da kasa (creatinine a ƙasa da 45 ml a minti ɗaya).
- Rashin ruwa na jiki, cututtukan cututtukan fata, rawar jiki, wanda ke kara saurin kamuwa da cutar koda.
- Cututtukan da ke kara haɗarin hypoxia. Waɗannan sun haɗa da mummunan / rauni na zuciya, bugun zuciya, ko gazawar numfashi.
- Ragewar hanta ko gazawar hanta.
- Ayyukan tiyata ko mummunan rauni da ke buƙatar maganin insulin.
- Abubuwan rage cin abinci mai kalori yayin ɗaukar sama da kcal 1000 a rana.
- Barasa maye ko giya mai sa maye.
- Amfani da sinadarin aidin wanda ya kunshi bambancin wakilai kafin da bayan awa 48 na gwaje-gwajen rediyo.
Ana amfani da Glucophage tare da taka tsantsan a cikin marasa lafiya na masu ciwon sukari, fiye da shekaru 60, wanda aikinsu yana da alaƙa da matsanancin ƙoƙari na jiki, tunda suna ƙara saurin haɓakar lactic acidosis. Marasa lafiya tare da dysfunction na koda ma sun fada cikin wannan jerin.
Sakamakon amfani da allunan da ba su dace ba ko don wasu dalilai, haɓakar halayen mara amfani yana yiwuwa. Umarnin ya bayyana abubuwan da zasu biyo baya:
- rikice-rikice a cikin narkewa na ciki - tashin zuciya ko amai, dandano na ƙarfe, zawo, ƙanshin ciki, ciwon ciki.
- halayen da ke kan fata - rashes, itching, erythema.
- bayyanar cutar megaloblastic.
- bayyanar lactic acidosis.
- take hakkin hanta ko hepatitis.
Bugu da ƙari, ana nuna sakamako mai illa a cikin abin da ya faru na rashin ƙarfi a cikin jikin bitamin B12.
Yawan rigakafin
Yana da matukar muhimmanci a san yadda ake shan Glucofage yadda yakamata, saboda yawan shansa na iya kawo sakamako mai cutarwa ga masu ciwon koda, wani lokacin ma mai kisa.
Yawancin karatu sun nuna cewa yin amfani da metformin a sashi na kimanin gram 85, wanda ya zarce mafi girma na yau da kullun ta hanyar sau 42.5, baya haifar da raguwa mai yawa a cikin ƙwayar cuta. Amma lactic acidosis na iya haɓaka, amma menene ke haifar da wannan yanayin?
Lactic acidosis, ko acidosis, babban sakamako ne na tarawar metformin. Idan babu ingantaccen magani da sauri, sakamako mai cutarwa yana yiwuwa. Lokacin ɗaukar Glucofage, ƙarin abin sha yana faruwa kamar haka:
- Seizures tare da cuta dyspeptic.
- Asthenia da ciwon ciki.
- Acidotic dyspnea.
- Rage zafin jiki.
- Ci gaban coma.
Idan mai haƙuri ya lura da akalla ɗayan alamun lactic acidosis, dole ne a tura shi nan da nan zuwa asibiti don kulawa ta gaggawa. Bayan haka, likita ya ƙayyade abubuwan da ke cikin lactate kuma ya bayyana maganin. Don cire metformin da lactate daga jiki, ana amfani da mafi yawan hemodialysis. Hakanan akwai magani don nufin kawar da alamun.
Glucophage da sauran jami'ai masu amfani da karfin jiki
Akwai takamaiman jerin magunguna, mai rikitarwa wanda ke haifar da rikitarwa mara amfani. Wasu daga cikinsu na iya haɓaka tasirin hypoglycemic na Glucophage, yayin da wasu - akasin haka, rage shi.
Ankare shi sosai don amfani da magungunan Glucophage da magungunan x-ray. A irin waɗannan halayen, damar yiwuwar faruwar lactic acidosis yana ƙaruwa. Idan kuna buƙatar ɗaukar irin waɗannan kuɗin, kuna buƙatar dakatar da ɗaukar Glucofage kafin da kuma bayan awoyi 48 na yin amfani da x-ray.
Yiwuwar acidosis a cikin ciwon sukari mellitus mai yiwuwa ne:
- a cikin mummunar guba.
- tare da karancin abinci mai gina jiki;
- tare da karancin kalori (kasa da 1000 kcal a kowace rana);
- tare da keta hanta.
Irin waɗannan kwayoyi kamar danazol, magungunan antihypertensive, salicylates, acarbose, injections insulin, sulfonylureas, nifedipine suna haɓaka tasirin sukari mai narkewar ƙwayar cuta.
Yana rage tasirin-glucose na glucophage irin wannan magani kamar GCS na gida da kuma tsari, chlorpromazine, beta-biyu-agrenergic agonists.
Hada “madauki” diuretics da glucophage, ya zama dole a tuna hadarin lactic acidosis a sakamakon lalacewar koda.
Wasu kwayoyi na iya shafar metformin, wato maida hankali. Wadannan sun hada da magungunan cationic - quinidine, digoxin, amiloride, quinine da sauransu.
Glucophage analogues
Yawancin magungunan hypoglycemic suna taimaka wa masu ciwon sukari da manyan alamu. Saboda haka, idan ba zato ba tsammani, saboda wasu dalilai, shan Glucophage ba zai yiwu ba, likitan na iya zaɓar wasu magunguna waɗanda suka yi kama da tasirin warkewar su.
Daga cikin su, magunguna dauke da abu guda mai aiki an rarrabe su - kalamai. Metformin ya ƙunshi samfuran kamar Bagomet, Siofor, Gliminfor, Metospanin, Gliformin, Metformin Forte da sauransu.
Siofor, magani ne mai rage sukari, wanda ya hada da povidone, magnesium stearate, hypromellose, titanium dioxide da polyethylene glycol, ya kasance sananne musamman a cikin samfuran da aka ambata a sama. Godiya ga amfani da magungunan Siofor, yana yiwuwa a cimma raguwar samar da glucose, karuwa a cikin tasirin ƙwayoyin tsoka ga insulin ɗin da aka samar, haka nan kuma da raguwa a cikin yawan narkewar glucose. Daga cikin abubuwan da ke haifar da mummunan sakamako da mummunar halayen, Siofor yana da kusan iri ɗaya da maganin da ake tambaya. Wanda ya ƙira Siofor shine Jamus, dangane da wannan kyakkyawar musanya ce ga Glucofage.
Magungunan ƙwayar cuta Glucophage da analogues suna samuwa - jami'ai waɗanda basu haɗa metformin ba a cikin abubuwan da suke ciki. Wadannan sun hada da:
- Glurenorm magani ne na antidiabetic wanda ke dauke da glycidone. Kasancewa mai samarda sinadarin sulfonylurea, Glurenorm yana saukar da matakin tashin hankali na rashin lafiyar glucose, yana karfafa samarda insulin, yana kara karfin jijiyoyin jikin sa, yana hana lipolysis a jikin mai, kuma yana rage tarin glucagon.
- Diabetalong sanannen magani ne wanda ya haɗa da gliclazide. Godiya ga aikin da miyagun ƙwayoyi, akwai tsari na metabolism metabolism, haɓaka samar da hormone mai rage sukari, kuma ana samun sakamako mai hana haɓaka haɓaka.
- Amaril M wani magani ne na ƙasar Jamusawa da ake amfani da shi don cututtukan da ba na insulin ba. Yana nufin abubuwan asali na ƙarni na uku na sulfonylurea. Sakamakon abun da ke cikin glimepiride a cikin abun da ke ciki, lokacin amfani da Amaril, yana yiwuwa a sami raguwar glucose din plasma da kuma haɓaka samar da insulin.
Idan kayi la'akari da abin da analogues Glucophage yake da shi, zaku iya samun sake dubawa game da Glucophage, da farashin wannan magani.
Cost da ra'ayi game da magani
A cikin kantin magani, ana iya siye magunguna kawai idan akwai takardar izini daga likita.
Yawancin marasa lafiya suna ba da umarnin magani akan layi, saboda wannan yana taimakawa don adana kuɗin su. Hakanan an bashi damar ganin hoto na kunshin da kwatancin sa.
Babu wani kamfanin Rasha da ke kera wannan samfurin, kamfanin kera magunguna na Faransa Merck Sante ne ya kera shi. To, yaya kudin Glucophage yake? Kudin wakilin antidi masu ciwon sukari ya dogara da yawan allunan da kuma sashi:
- 1000 mg (A'a. 60) - daga 270 zuwa 346 rubles;
- 850 MG (A'a. 60) - daga 150 zuwa 180 rubles;
- 500 MG (A'a. 60) - daga 183 zuwa 230 rubles.
Kamar yadda kake gani, an yarda da maganin Glucofage. A Intanet, zaku iya ganin maganganu masu yawa game da amfani da Glucophage. Misali, bita Mariya (shekaru 56): "Na ga Glucofage har na tsawon shekaru biyu. A wannan lokacin, matakan sukari sun koma al'ada, ba shakka, ina yin biyayya ga tsarin abinci lokacin shan magani. Na sami damar rasa fam biyu."
Game da miyagun ƙwayoyi Glucofage sake dubawa na iya zama mara kyau. Wannan shi ne sakamakon sakamako masu illa yayin daidaitawar jiki zuwa metformin. A wasu majinyata, ana yin tasirin sakamakon haka ne da ba sa shan wannan magani.
Hakanan zaka iya samun nazarin likitocin da suka danganci amfani da kwayoyi don asarar nauyi. Ra'ayin mafi yawan masana a wannan yanayin mara kyau ne. Suna ba da shawarar sosai kada amfani da miyagun ƙwayoyi don wannan dalili.
Glucophage magani ne mai inganci wanda endocrinologists da yawa suna ba da shawara don magance nau'in ciwon sukari na 2. Idan har yanzu baku dauki wannan magani ba, gwada Glucofage, kuma idan kun riga kun sha, ku kara shan shi sosai. Fa'idodin wakilin antidi masu cutar sau da yawa sunfi girman halayensa mara kyau.
Ana ba da bayani game da ƙwayar glucofage na glucose a cikin bidiyon a cikin wannan labarin.