A yau, cututtukan zuciya suna cikin matsayi na farko a cikin cututtukan da ke haifar da mutuwar mutum. Mafi sau da yawa, cin zarafin yana haifar da atherosclerosis, wanda aka kirkiro saboda tarawar mummunan cholesterol da plasta cholesterol a cikin jiki.
Don kauce wa mummunan rikice-rikice na ciwon sukari, yana da mahimmanci don fara magani a cikin dace. Bayan yin nazari da bincike, likitan da ke halartar zai sanar da kai wane nau'in kwarokwaro ne mafi inganci kuma mai lafiya.
Magungunan suna iyakance hanta, da ƙ asa sanya ƙananan ƙwayar lipids a cikin jini, tsabtace tasoshin jini da inganta yanayin rayuwar mai haƙuri.
Iri da kwayoyi
Statins na iya zama na halitta da na roba, waɗanda aka ƙirƙira su da wucin gadi. Hakanan, magungunan cholesterol sun kasu kashi hudu.
Magungunan ƙarni na farko sun haɗa da siffofin halitta, waɗanda ke ware daga fungi. Magungunan sauran tsararrun abubuwa ana haifar su ne ta hanyar motsawa ta zahiri.
Simvastatin da Lovastatin sune mutum-mutumi ne na farko. Ba su da tasirin warkewa da ke ƙasa kuma suna haifar da sakamako masu illa iri-iri. Yin amfani da tsayi yana buƙatar magungunan ƙarni na biyu, wanda ya haɗa da fluvastatin. Ana iya adanar su a cikin jinin mutum na dogon lokaci.
Magunguna na ƙarni na uku suna ba da gudummawa ga raguwa mai mahimmanci a cikin taro na triglycerides da ƙarancin lipoproteins, daga cikinsu ana ɗaukar Atorvastatin shahararrun. Shirye-shirye don tasirin cholesterol na sabon ƙarni na huɗu suna ba da gudummawa ga haɓaka ingantaccen aiki da aminci, idan aka kwatanta da tsoffin analogues.
Baya ga ayyukan asali na rage darajar kiba, kwayoyi suna da fasali na musamman da ƙarin tasirin.
Kayan Statin
Magungunan ƙwayar statin suna shafar samar da cholesterol ta hanta ta hanyar hana shi. Wannan na faruwa ne saboda gaskiyar cewa enzymes da ke cikin kwayar cholesterol ana toshe su. Wadannan enzymes suna haɓaka haɓakar ƙwayoyin mevalonic acid, wanda ke aiki azaman maganin ƙwayoyin cuta.
Statins kuma suna shafar endothelium na tasoshin jini, rage kumburi da rage haɗarin ƙwanƙwasa jini, haɓaka aikin sinadarin nitric oxide, wanda ke daidaita da kwantar da jijiyoyin jini, yana tabbatar da lafiyar zaman sinadarai na jini.
Bugu da ƙari, kwayoyi suna hana infarction na zuciya. Don haka, alal misali, Rosuvastatin ya tabbatar da kasancewa ingantaccen magani wajen rage haɗarin ciwan cututtukan zuciya. A lokacin farfadowa bayan bugun zuciya, ashe mutum ne wanda aka dauka, tunda suna taimakawa hanzarta hanyar warkarwa.
Haɗe da Allunan zai iya ƙara matakin kyakkyawan lipids.
Amfanin statins
Ana amfani da waɗannan nau'ikan magungunan don rigakafi da magani na atherosclerosis, lokacin da sauran hanyoyin maganin ba su nuna tasirin da ake so ba. Statins rage hadarin bugun zuciya, tashin hankali ischemic attack, bugun jini, atherosclerosis.
Hakanan, allunan suna daidaita aikin tsarin jijiyoyin jini a cikin cututtukan jijiyoyin zuciya da angina pectoris, dakatar da alamun cututtukan sukari, rage nauyi a cikin kiba, da rage kumburi a jikin bangon jijiyoyin jini. Magunguna na iya yin bakin jini da hana haɓakar thrombosis, daidaita hanyoyin tafiyar matakai, faɗaɗa jijiyoyi, da kuma cire filayen atherosclerotic.
Magungunan yana ba ka damar hanzarta farfadowa tare da stenting, ischemic bugun jini, na jijiyoyin zuciya jiyya grafting, angioplasty, myocardial infarction, na huhun hanji embolism.
Wanda ke contraindicated da statin jiyya
Kafin farawa, ya kamata ka nemi likita. Zai taimake ka ka zabi magani da sashi, la'akari da halayen mutum na jiki da kasancewar ƙananan cututtuka. Tunda satins suna da contraindications da yawa, ba za a taɓa yi wa kai magani ba.
Yin amfani da miyagun ƙwayoyi ya kamata a watsar da shi gaba ɗaya a gaban halayen rashin lafiyan da kuma rashin haƙuri ga abubuwa masu amfani na miyagun ƙwayoyi, cututtukan koda, glandar thyroid da tsarin endocrine.
Hakanan, ba za a iya amfani da allunan ba idan an keta tsarin musculoskeletal, m da cututtukan hanta na hanta. A cikin ciwon sukari na mellitus, yakamata a kula musamman yayin zabar wata hanyar rage cholesterol. A lokacin daukar ciki, ƙwayar na iya cutar da tayin, saboda haka ya fi kyau maye gurbin magani tare da wani zaɓi mai lafiya ko kuma dakatar da magani gaba ɗaya.
Kuna buƙatar fahimtar cewa shan magani na iya haifar da wasu sakamako masu illa.
- A cikin lokuta masu saukin ganewa, myopathy ya haɗu. Irin wannan cin zarafi ya dogara da shekaru na haƙuri, kashi na miyagun ƙwayoyi, kasancewar matsanancin rikitarwa na ciwon sukari.
- Wani lokacin aikin tsakiya mai lalacewa yana rushewa. Wannan yana bayyana kanta a cikin nau'in ciwon kai, tsananin farin ciki, tashin hankali na barci, rauni gaba ɗaya.
- Lokacin da aka fallasa shi ga tsarin numfashi a wasu yanayi, rhinitis, mashako na haɓaka.
- Hakanan, mai haƙuri na iya fuskantar tashin zuciya, amai, maƙarƙashiya.
Gabaɗaya, tare da daidaituwa, hankali da dacewa ga allunan, zaka iya ganin sakamako mai kyau. Amma idan ya kasance yawan overdose da tsawaita amfani, mai haƙuri zai iya fuskantar halayen da ba daidai ba ta hanyar:
- Jin zafi a ciki da ƙananan hanji, maƙarƙashiya, amai;
- Amnesia, rashin bacci, paresthesia, dizzness;
- Thrombocytopenia ko raguwa mai yawa a cikin taro platelet
- Kumburi, kiba, rashin ƙarfi a cikin maza;
- Muscle cramps, ciwon baya, amosanin gabbai, myopathy.
Hakanan, ana iya lura da sakamako wanda ba a ke so ba idan an yi amfani da cututtukan fata da sauran nau'ikan magunguna masu jituwa da ƙari.
Abvantbuwan amfãni da rashin amfani na statins
Idan kuna kulawa da kullun kuma ku bi duk shawarwarin likita, wannan rukuni na kwayoyi suna rage haɗarin mace-mace daga bugun zuciya da bugun jini da kashi 40 cikin ɗari. Magungunan na iya rage taro da mummunan cholesterol a cikin jini da kashi 50. Don tantance yanayin, ana ba da shawarar sau ɗaya a wata don ba da gudummawar jini zuwa matakin lipids mai cutarwa.
Wannan magani ne mai lafiya, wanda, aka ba da magani, baya da tasiri mai guba a jiki. Sabbin kwayoyi na zamani suna da ƙarancin sakamako masu illa da, ba tare da sakamako ba, ba da izinin magani ga ciwon sukari. A yau, akwai analogues da yawa don siyarwa a kan farashi mai araha, saboda haka kowa zai iya zaɓar magani, yana mai da hankali ga ikon kuɗi.
Rashin daidaituwa ya haɗa da babban farashi, shirye-shiryen asali Rosucard, Krestor, Leskol Forte suna da tsada musamman.
Amma a kan shelves koyaushe akwai allunan masu rahusa, wanda na iya ƙunsar abu guda mai aiki mai aiki.
Mafi inganci da amintattun siffofin
Don amsa tambaya game da abin da statins na iya inganta yanayin mutum ba tare da lahani ga lafiyar ba, an gudanar da binciken kimiyya da yawa. A sakamakon haka, ya juya cewa mafi inganci da ƙarancin magunguna Atorvastatin. A matsayi na biyu ba shi da amintacce mai inganci da ingantaccen Rosuvastatin, kuma a cikin na uku - Simvastatin.
Likita na iya yin allurar atorvastatin don maganin cututtukan zuciya da jijiyoyin jini. Wannan magani ya tabbatar da kansa a cikin karatun asibiti da yawa kuma a aikace ya tabbatar yana iya rage hadarin bugun jini da kashi 50. Dangane da shaidar likitan, sashi shine 40-80 MG da safe ko da yamma, ya danganta da matsayin cutar.
Rosuvastatin magani ne wanda ba asalin halitta ba. Yana da tasiri mai amfani da hydrophilic, wanda ke haifar da rage tasirin sakamako kuma dakatar da haifar da mummunan cholesterol. Ba kamar sauran allunan ba, ƙwayar ba ta tsokani cutar sankara da tsoka ba.
- A kashi 40 MG rage matakin low low lipoproteins da kashi 40 da kuma ƙara maida hankali ne mai kyau cholesterol da 10 kashi.
- Sakamakon amfani da miyagun ƙwayoyi ana iya lura dashi bayan kwana bakwai, bayan wata daya sakamakon ya isa matsakaicinsa, kuma za'a iya kiyaye wannan yanayin na dogon lokaci.
Simvastatin na iya rage hadarin kamuwa da cututtukan jijiyoyin jiki da cututtukan zuciya da kaso 10 cikin dari bayan bugun zuciya, bugun jini, da ciwon suga. Idan kun dauki maganin na dogon lokaci, zaku iya daidaita tasirin mummunan aiki da cholesterol mai kyau, rage haɗarin ƙwayar cuta na jijiyoyin jini.
Kamar yadda likitoci suka lura a cikin bita-da-kullin, statins sune amintattun magunguna. Amma yana da mahimmanci a karanta umarnin kafin amfani, la'akari da halayen mutum na jiki, bi sosai sashi, taka tsantsan a gaban ƙananan cututtuka kuma kada kuyi magani da kansu.
Don inganta yanayin janar, ana bada shawara don yin kayan ado na ganyayyaki na ganye, hada abinci na shuka a cikin menu, kuma amfani da girke-girke mai aminci yayin dafa abinci.
Haka magunguna
Kowane ɗayan magungunan da ke sama suna da sunan kasuwanci daban. Saboda haka, likitan halartar na iya yin irin wannan tsarin na halitta ko, a taqaice, magungunan roba a mafi kyawun farashi.
Abunda ke aiki na Simvastatin shine babban abu mai mahimmanci wanda ke da tasirin rage ƙwayar lipid. Jerin analogues ya hada da Zovatin, Arieskor, Simvakor, Simgal, Vasilip, Zosta, Zokar, Simvastol, Vastatin.
Za'a iya maye gurbin miyagun ƙwayoyi na Pravastatin na farko da Pravospres, Lipostat. Gidajen gini na Lovastatin sun hada da Mevacor, Lovagexal, Lovacor, Apextatin, Rovacor, Holetar, Cardiostatin, Medostatin, Lovasterol, Liprox.
Magungunan Atorvastatin sun hada da Tulip, Canon, Atoris, Atorvox, Atomax, Lipitor, Liprimar, Torvakard, Anvistat, Liptonorm. Babu ƙarancin inganci da amintattun analogues na Rosuvastatin don rage ƙwayar jini sune Rosart, Rosulip, Roxera, Krestor, Tevastor, Mertenil, Novostatin, Akorta.
An bayyana Statins a cikin bidiyon a cikin wannan labarin.
