Cocarnit shiri ne mai rikitarwa wanda ya ƙunshi bitamin B da triphosadenine. Amfani da shi don kula da polyneuropathy na ciwon sukari, neuralgia, ciwon tsoka. Hakanan ana amfani dashi don inganta metabolism a cikin cututtuka na tsarin zuciya.
ATX
A11DA (Vitamin B1).
Cocarnit shiri ne mai rikitarwa wanda ya ƙunshi bitamin B da triphosadenine.
Saki siffofin da abun da ke ciki
Lyophilisate don shirin bayani mai ruwan hoda, ampoules na 3 ml a cikin kunshin sel. Ampoule 1 ya ƙunshi:
- Trifosadenin 10 MG.
- Nicotinamide - 20 MG.
- Cyanocobalamin - 0.5 mg.
- Cocarboxylase - 50 MG.
Waɗanda suka ƙware: glycine 105.8 MG, abubuwan kiyayewa (methyl parahydroxybenzoate - 0.6 mg, propyl parahydroxybenzoate - 0.15 mg). Magani: lidocaine hydrochloride - 10 MG, ruwa don yin allura - 2 ml.
Aikin magunguna
A miyagun ƙwayoyi hadadden bitamin biyu, coenzyme daya da kuma na rayuwa abu.
Trifosadenin kayan aiki ne wanda ya ƙunshi haɗin macroergic wanda ke ba da makamashi ga tsarin juyayi da ƙwayar zuciya. Yana da sakamako mai illa da kyawun cuta. Yana faɗaɗa jijiyoyin zuciya da jijiyoyin wuya. Inganta metabolism na jijiya nama.
Trifosadenin kayan aiki ne wanda ke ɗauke da ƙwayoyin macroergic wanda ke ba da ƙarfi ga ƙwaƙwalwar zuciya.
Nicotinamide - bitamin PP, yana shiga cikin ayyukan makamashi, halayen da ke faruwa na sake zagayowar Krebs. Inganta carbohydrate da furotin metabolism, wayar salula. Yakan rage kiba.
Cyanocobalamin - bitamin B12. Rashin wannan abun yana haifar da zakara wanda bai iya aiki ba, ayyuka masu rauni na igiyar kashin baya da kuma tsarin juyayi na gefe. Kyauta ne na kungiyoyin methyl don rage matakin homocysteine, wanda ke cutar da tsarin jijiyoyin jini. Yana haɓaka sakewar sel.
Cocarboxylase wani coenzyme ne na enzyme carboxylase wanda ke daidaita haɗe-haɗe da ɓarnar ƙungiyoyin carboxyl zuwa ga alpha-keto acid. Yana nufin antihypoxants, yana ƙaruwa da juriya na rashin ƙarfi ga ƙarancin oxygen. Yana rage taro na lactate da pyruvate a cikin cardiomyocytes da jiki. Ya shiga cikin tsarin acid na nucleic, sunadarai, fats.
Pharmacokinetics
Trifosadenin ya rushe a cikin sel zuwa cikin phosphates da adenosine, waɗanda aka haɗo su da tsarin samar da kwayoyin halittar ATP don bukatun makamashi na jiki, gami da ƙwayar jijiya da zuciya.
Cocarboxylase ya shiga cikin kyallen takarda, an haɗo shi a cikin matakan metabolism, sannan ya lalata. Abubuwan lalacewa suna narkewa a cikin fitsari.
Ana ɗaukar Cyanocobalamin ta hanyar transcobalamin sunadarai a cikin nama, mafi yawan hanta, ajiyayyun shi daga ciki. Canzawa zuwa 5-deoxyadenosylcobalamin. Abun kariya a cikin kariya shine 0.9%. Kasancewa cikin hanzari bayan kammala aikin gwamnati. Ana samun mafi girman maida hankali awa daya bayan allura ta wucin gadi. Cire rabin rayuwar shine kwana 500. An keɓe shi ga mafi yawan sashin hanji - kusan 70-100%, 7-10% barin jiki ta hanyar kodan. Penetrates ta cikin mahaifa, har zuwa cikin nono.
Cyanocobalamin shine mafi yawan hanta da aka ajiye shi, daga inda yake biye da shi ta hanyar bile.
Nicotinamide yana cikin hanzari rarraba cikin jiki. Yana cikin metabolized ta hanta - an kirkiro nicotinamide-N-methylnicotinamide. Cire rabin rayuwar shine 1.3 hours. An cire shi ta hanyar kodan, share 0.6l / min.
Alamu don amfani
An ba da alama ga mai ciwon sukari na ciwon sukari (goosebumps, neurogenic pain), cututtukan zuciya da na jijiyoyin jini, neurocirculatory dystonia, a cikin lokaci bayan murmurewa daga bugun jini da bugun zuciya, yayin tashin hankali ischemic na rauni, fainting. Umarnin don amfani yana nuna sciatica, radiculitis.
Contraindications
Contraindicated idan akwai wani hypersensitivity ga miyagun ƙwayoyi, ƙara yawan coagulation jini, ciki, lactation, a karkashin shekara 18 shekaru, m zuciya gazawar, thromboembolism, hemorrhagic bugun zuciya, hanawa hanji, bronchial fuka, cirrhosis na hanta, hepatitis, exacerbation na na ciki ko duodenal miki.
Ba za ku iya amfani da miyagun ƙwayoyi don hauhawar jini ba, tashin hankali, tsawaita tazara ta QT, bugun zuciya, bradyarrhythmias.
Ba za ku iya amfani da miyagun ƙwayoyi don hauhawar jini ba tare da kulawa ba.
Yadda ake ɗaukar Cocarnit
Lokacin amfani da miyagun ƙwayoyi, kuna buƙatar sanin yadda ake shan shi.
Abin da za a yi kiwo
Tsarma 2 ml na 0.5% (10 mg) ko 1 ml na lidocaine 1% tare da 1 ml na ruwa don yin allura.
Shan maganin don ciwon sukari
An sanya allura mai zurfi a cikin tsoka. Aikin shine kwana 9 na ampoule 1. Bayan cire ciwo mai raunin ciwo, ana ci gaba da warkewa - injections ake yi kowace kwana 2-3. Aikin ne makonni 3.
Side effects
Magungunan zai iya haifar da sakamako masu illa.
Gastrointestinal fili
Ciwon hanci, amai, gudawa - da wuya.
Hematopoietic gabobin
Increasearuwar yawan ƙwayoyin jan jini, sel fararen jini, platelet.
Tsarin juyayi na tsakiya
Jin daɗi, ciwon kai, vertigo.
Daga gefen tsarin juyayi na tsakiya, sakamako masu illa a cikin nau'in ciwon kai yana yiwuwa.
Daga fata da ƙananan ƙwayoyin cuta
Daga fata da ƙananan kasusuwa - rashes, itching, redness na fata, kuraje, gumi.
Daga tsarin rigakafi
Cutar ƙodar Quincke, ƙaiƙayi, fitsari.
Daga gefen zuciya
Arrhythmia, tachy da bradycardia, ciwon kirji, rage matsin lamba.
Cutar Al'aura
Murmushi Anaphlactic, amai da fata.
Mai haƙuri na iya fuskantar alamun bayyanar rashin lafiyan ta hanyar fatar fata.
Umarni na musamman
Jiyya tare da miyagun ƙwayoyi ya kamata ya kasance tare da maganin cututtukan mellitus tare da taimakon magungunan hypoglycemic. Idan bayyanar cututtuka ta lalace ko babu canje-canje masu kyau, an daidaita tsarin.
Ana amfani da maganin nan da nan bayan shiri. Yakamata ya sami launin ruwan hoda. Lokacin da ya canza, ba za a iya amfani da miyagun ƙwayoyi ba.
Tasiri kan ikon sarrafa abubuwan inji
Abubuwan da ke haifar da sakamako masu yiwuwa - rashin jin daɗi, ƙwaƙwalwar ido. Lokacin da suka faru, ba za ku iya fitar da motoci da abubuwan haɗin keɓaɓɓu ba.
Abubuwan da ke haifar da sakamako masu yiwuwa - rashin jin daɗi, ƙwaƙwalwar ido.
Yi amfani da lokacin daukar ciki da lactation
An hana shi. Lokacin shan maganin, sun ƙi ciyar.
Cockarnit sashi na yara
An sanya ƙwayar maganin har zuwa shekara 18.
Yi amfani da tsufa
Ba a buƙatar gyaran gyaɗa.
Yawan damuwa
Sakamakon abun ciki na bitamin PP tare da amfani na tsawan lokaci, miyagun ƙwayoyi na iya haifar da cututtukan hanta mai rauni saboda rashi na rukunin methyl. Tare da yawan ƙwayar cyanocobalamin, matakan folic acid yana raguwa.
Yin hulɗa tare da wasu kwayoyi
Cyanocobalamin bai dace da bitamin B1, B2, B6, folic, ascorbic acid, karafa mai nauyi (De-nol, Cisplatin), barasa.
Cyanocobalamin bai dace da barasa ba.
Tare da amfani da lokaci guda na biguanides (Metformin) tare da kwayoyi tare da raunin glucose mai rauni, maganin aminoglycoside, salicylates, potassium, colchicine, anticonvulsants, yawan shan bitamin B12 an rage shi.
Don guje wa hypercoagulation, ba za ku iya amfani da magungunan da ke haɓaka danko na jini ba.
Cyanocobalamin bai dace da chloramphenicol ba.
Yana haɓaka tasirin vasodilating na dipyridamole.
Purines - Caffeine, Theophylline - masu adawa da miyagun ƙwayoyi.
Lokacin amfani da glycosides na zuciya, haɗarin sakamako masu illa suna ƙaruwa.
Nicotinamide yana haɓaka tasirin tashin hankali, maganin kwantar da hankali da rage ƙwayoyi
Xanthinol nicotinate yana rage tasirin maganin.
Mai masana'anta
World Medical Limited.
Analogs
Babu kudade tare da cikakken kayan aiki iri ɗaya. Koyaya, akwai magunguna na rayuwa - sodium adenosine triphosphate, cocarboxylase, Allunan nicotinic acid, cyanocobalamin.
Magunguna kan bar sharuɗan
An sake shi ta hanyar takardar sayan magani. Jerin B.
Farashin Cocarnith
Farashin 3 ampoules shine 636 rubles.
Yanayin ajiya na miyagun ƙwayoyi Kokarnit
Adana a cikin busassun a zazzabi na + 15 ... + 25 ° С.
Ranar karewa
Shekaru 3 Magani shine shekaru 4.
Reviews game da Kokarnit
Nastya
Magungunan ba su da arha, amma ciwo tare da radiculitis an cire shi daidai. Dogara 12 injections.
Katarina V.
Ciwon sukari na 2 wani babban cuta ne. Tana bayyanar da kanta cikin jin zafi a hannu da kafafu. Haye hanya na makonni 3. Kwayar cutar polyneuropathy ta ragu sosai. Ya zama da sauki tafiya.
Bitrus
Ina rashin lafiya da ciwon sukari na 2 da angina pectoris. Likita ya ba da umarnin allura da maganin a kowace rana da ampoule ɗaya don zafin ya tafi. Na yi tsawon kwanaki 5 ina kwanciya, lafiyata ta inganta, raɗaɗin a hannuna ya sauƙaƙa. Ko da matsin ya sauka dan kadan sai ciwon zuciya ya zama baya yawaita.
