Tegretol CR - magani ne mai tazara wanda ke haɓaka ƙarshen shiri mai ƙarfi, don haka hana faruwar hare-hare.
Sunan kasa da kasa mai zaman kansa
Carbamazepine.
Tegretol CR - magani ne mai hana haihuwa wanda ke tayar da ƙarancin shirye shirye.
ATX
Lambar ATX ita ce N03AF01.
Saki siffofin da abun da ke ciki
Ana amfani da miyagun ƙwayoyi a cikin nau'ikan allunan da aka rufe. Allunan suna da siffar biconvex.
Abubuwan da ke aiki mai aiki a cikin allunan na iya zama 200 MG ko 400 MG. Abubuwan da ke aiki shine carbamazepine.
Ana samun allunan 200 MG a cikin fakitin fakiti guda 50. A cikin fakitin 5 blisters na guda 10.
Akwai allunan 400 MG a cikin fakitoci na guda 30. A cikin fakitin 3 blisters na guda 10.
Aikin magunguna
Ana nuna Carbamazepine don sauƙaƙewar tashin zuciya. Babban sinadaran aiki na maganin shine maganin asalin dibenzoazepine. Yana da tasirin maganin rigakafi tare da neurotropic har da psychotropic.
Ba a yi nazarin aikin kimiyyar magunguna ba. Akwai bayani cewa sashinda ke aiki yana shafar membranes na sel, yana tsayar da su kuma yana hana ciwan gaba. Wannan kuma yana faruwa ne saboda hanawa da hanzarin ƙwaƙwalwar ƙwaƙwalwa, saboda wanda akwai hauhawar tsarin jijiyoyi.
Yin amfani da Tegretol a cikin marasa lafiya da ke fama da cututtukan ƙwayar cuta yana tattare da ɓacin da alamun bayyanar cututtuka masu tasiri.
Babban abin da ke tattare da ayyukan miyagun ƙwayoyi yana toshewa da sake dawo da hankalin neurons bayan lalacewa. Wannan ya faru ne sakamakon rashin tasirin tashoshi na ion wanda ke ba da jigilar sodium.
Nazarin ya nuna cewa yin amfani da Tegretol a cikin marasa lafiya da ke fama da cututtukan ƙwayar cuta yana tattare da ƙin bayyanar cututtukan ƙwaƙwalwa masu tasiri: tashin hankali, tashin hankali da ƙara damuwa.
Babu wata tabbatacciyar shaida game da ko carbamazepine yana rinjayar ƙimar halayen psychomotor da damar iyawa na marasa lafiya. A yayin wasu nazarin, an samo bayanan rigima, wasu sun nuna cewa maganin yana inganta kwarewar fahimta.
Tasirin neurotropic na Tegretol yana ba ku damar amfani da shi don maganin cututtukan cututtukan cututtukan zuciya. An wajabta shi ga marasa lafiya tare da nural nesia. trigeminus don sauƙin kai harin na bazata lokaci-lokaci yana haifar da jin zafi.
An tsara masu haƙuri da shan giya don rage haɗarin kamuwa da cuta.
An tsara masu haƙuri da shan giya don rage haɗarin kamuwa da cuta. Hakanan yana rage tsananin tsananin bayyanar cututtukan cututtukan cututtukan zuciya.
A cikin mutanen da ke fama da ciwon sukari insipidus, yin amfani da wannan magani yana daidaita al'ada diuresis.
Ana amfani da tasirin psychotropic na tegretol don magance raunin tunani mai illa. Ana iya amfani dashi duka daban kuma a hade tare da sauran magungunan rigakafin ƙwayoyin cuta, maganin cututtukan fata. An yi bayanin rage bayyanar cututtuka na manic ta hanyar yuwuwar hana ayyukan dopamine da norepinephrine.
Pharmacokinetics
Kasancewa cikin kayan aiki yana faruwa ta hanjin mucosa. Releaseaddamarwarsa daga allunan jinkirin, wanda ke ba da izinin sakamako mai tsawo. Matsakaicin mafi kyawun abu a cikin jini ya kai cikin awa 24. Yana da ƙasa the ƙasa da maida hankali lokacin ɗaukar daidaitaccen tsarin magani.
Saboda jinkirin sakin abu mai aiki, canji a cikin maida hankali a cikin plasma ba shi da mahimmanci. A bioavailability na carbamazepine lokacin ɗaukar allunan jinkiri-an rage su da 15%.
Lokacin da ya shiga cikin jini, sashin jiki mai aiki yana ɗaukar jigilar peptides da kashi 70-80%. Yana haye cikin mahaifa kuma cikin madara. Cutar da ƙwayoyi a ƙarshen zai iya zama sama da 50% na alamomin guda ɗaya a cikin jini.
A bioavailability na carbamazepine lokacin ɗaukar allunan jinkiri-an rage su da 15%.
Metabolism na abu mai aiki yana faruwa a ƙarƙashin rinjayar enzymes hanta. Sakamakon canje-canje na sunadarai, an samar da metabolites mai aiki na carbamazepine da mahallinsa tare da glucuronic acid. Bugu da kari, an samar da karamin adadin metabolite mara aiki.
Akwai hanyar rayuwa wanda bashi da alaƙa da cytochrome P450. Don haka ake samar da mahaukatan sunadarai masu guba na carbamazepine.
Rabin rayuwar rayuwa mai aiki shine awa 16-36. Ya dogara da tsawon lokacin aikin likita. Tare da kunna enzymes na hanta ta wasu magunguna, ana iya rage rabin rayuwar.
2/3 na miyagun ƙwayoyi an keɓe ta ta hanyar kodan, 1/3 - ta cikin hanji. An kusan dakatar da miyagun ƙwayoyi a cikin hanyar metabolites.
Alamu don amfani
Alamu masu amfani da wannan kayan aikin sune:
- epilepsy (wajabta shi ga duka mai sauƙi da gauraye da sarkakkiyar jigilar ciki);
- bipolar shafi cuta;
- m manic psychosis;
- trigeminal neuralgia;
- mai ciwon sukari mai ciwon sukari, tare da raɗaɗi;
- ciwon sukari insipidus tare da ƙara diureis da polydipsia.
Contraindications
Yin amfani da Tegretol ya ta'allaka ne a wadannan lamura:
- daidaikun mutane game da aiki mai aiki ko wasu abubuwan magunguna;
- toshewa;
- barasa cire ciwo;
- take hakki mai narke jini a cikin kashi;
- m intermittent porphyria;
- haɗuwa da miyagun ƙwayoyi tare da inhibitors monoamine oxidase.
Yadda ake ɗaukar Tegretol CR
Abinci baya shafar tasirin maganin. Ana ɗaukar kwamfutar hannu duka kuma an yi wanka da shi tare da adadin ruwa da ake buƙata.
Monotherapy tare da Tegretol mai yiwuwa ne, kuma haɗe tare da sauran jamiái.
Tabbataccen tsari game da amfani da miyagun ƙwayoyi ya ƙunshi gudanarwa na lokaci biyu na allunan. Sakamakon magungunan magunguna tare da tasirin sakamako, ana iya buƙatar karuwa a cikin abubuwan yau da kullun.
Ana ɗaukar kwamfutar hannu duka kuma an yi wanka da shi tare da adadin ruwa da ake buƙata.
Mutanen da ke da santi suna da shawarar tegretol monotherapy. Na farko, ana sanya ƙananan allurai, wanda sannu a hankali yana ƙaruwa zuwa misali. Shawarwarin farko na maganin shine 100 MG 1 ko sau 2 a rana. Mafi kyawun kashi ɗaya shine 400 MG sau 2-3 a rana. A wasu halaye, kuna iya buƙatar ƙara yawan adadin yau da kullun zuwa 2000 MG.
Tare da neuralgia n. trigeminus matakin farko na yau da kullun ya kai 400 MG. Increasesarin ƙaruwa zuwa 600-800 MG. Tsofaffi marasa lafiya suna karɓar kashi 200 na magani a rana.
An wajabta wa mutanen da ke dauke da shan barasa daga 600 zuwa 1200 mg / rana. A cikin alamun bayyanar cututtuka masu guba, ana haɗuwa da miyagun ƙwayoyi tare da magungunan rigakafi
An tsara marasa lafiyar da ke fama da matsanancin halin damuwa daga 400 zuwa 1600 MG na Tegretol kowace rana. Farji yana farawa da ƙarancin ƙwayoyi, wanda a hankali yana ƙaruwa.
Tare da ciwon sukari
An nuna Carbamazepine ga marasa lafiya da ke fama da ciwon sukari. Magungunan yana dakatar da jin zafi wanda ke faruwa sakamakon canje-canje na rayuwa a cikin ƙwayar jijiya. Shawarwarin da aka ba da shawarar yau da kullun don maganin ciwon sukari shine 400 zuwa 800 MG.
An nuna Carbamazepine ga marasa lafiya da ke fama da ciwon sukari.
Sakamakon sakamako na Tegretol CR
A wani bangare na bangaren hangen nesa
Zai iya faruwa:
- rikice-rikice a cikin dandano mai dandano;
- maganin kumburi;
- tinnitus;
- hypo-hyperacusia;
- girgije daga ruwan tabarau.
Daga tsoka da kashin haɗin kai
Wadannan m halayen na iya faruwa:
- ciwon tsoka
- hadin gwiwa zafi.
Gastrointestinal fili
Aukuwa irin wannan da ba a so halayen mai yiwuwa ne:
- tashin zuciya
- amai
- kumburi da bakin mucous na bakin;
- canza yanayin yanayin kujera;
- kumburin koda;
- canza a cikin matakin ayyukan enzymes hanta.
Hematopoietic gabobin
Zasu iya amsa magani tare da bayyanar:
- leukopenia;
- thrombocytopenia;
- agranulocytosis;
- anemia
- rage matakan folic acid.
Kwayoyin Hematopoietic na iya amsawa ga jiyya tare da thrombocytopenia.
Tsarin juyayi na tsakiya
Zai iya amsawa ga rashin lafiyar tare da halayen masu illa:
- Dizziness
- ciwon kai
- na gefe neuropathy;
- paresis;
- rashi magana;
- rauni na tsoka;
- nutsuwa
- hallucinatory syndrome;
- karuwar rashin damuwa;
- rikicewar damuwa;
- hangen nesa biyu
- rikicewar motsi;
- rikicewar hankali;
- gajiya.
Tsarin juyayi na tsakiya na iya amsawa ga jiyya tare da hangen nesa biyu.
Daga tsarin urinary
Zai yiwu a lura:
- fitar;
- pollakiuria;
- urinary riƙewa.
Daga tsarin numfashi
Dalili mai yiwuwa:
- karancin numfashi
- ciwon huhu.
A ɓangaren fata
Zai yiwu a lura:
- ɗaukar hoto;
- dermatitis;
- itching
- erythema;
- hirsutism;
- alamu;
- rashes;
- hyperhidrosis.
Daga tsarin kare jini
Lokaci na rashin ƙarfi na iya faruwa.
Daga tsarin kulawa, rashin ƙarfi na ɗan lokaci na iya faruwa.
Daga tsarin zuciya
Zai iya faruwa:
- toshewa;
- arrhythmia;
- raunin zuciya;
- wuce gona da iri alamun bayyanar cututtuka na zuciya.
Tsarin Endocrin
Bayyanar bayyanar:
- kumburi;
- gynecomastia;
- hyperprolactinemia;
- hawan jini.
Daga gefen metabolism
Zai iya faruwa:
- hyponatremia;
- dagagge triglycerides;
- increaseara yawan taro.
Cutar Al'aura
Bayyanar bayyanar:
- halayen rashin kwanciyar hankali;
- lymhadenopathy;
- zazzabi
- angioedema;
- maganin ciwon hanji.
Daga ɗaukar Tegretol CR a matsayin sakamako na gefen, mai haƙuri na iya lura da zazzabi.
Tasiri kan ikon sarrafa abubuwan inji
Abubuwan haɗari masu haɗari masu alaƙa da haɗuwa da hankali ya kamata a guji yayin shan carbamazepine. Wannan shi ne saboda yiwuwar sakamako masu illa daga tsarin juyayi.
Umarni na musamman
Yi amfani da tsufa
A wasu halaye, ana iya buƙatar daidaita sakin yau da kullun.
Aiki yara
Ana iya ba da magani ga yara. Yawan maganin yau da kullun ya tashi daga 200-1000 MG, ya danganta da shekaru da nauyin mai haƙuri. Lokacin da ake rubuta magungunan, ana ba da shawarar yara 'yan ƙasa da shekaru 3 su zaɓi magani a cikin sikirin.
Yi amfani da lokacin daukar ciki da lactation
Dole ne a gudanar da aikin tiyata tare da carbamazepine yayin daukar ciki tare da taka tsantsan. Ka lura da gaskiyar cewa tegretol na iya ƙara ƙarancin bitamin B12 a cikin mata masu juna biyu.
Lokacin da kake kulawa da mahaifiyar mai reno tare da carbamazepine, yakamata a canza yarinyar zuwa abinci mai wucin gadi. Cigaba da ciyarwa mai yiwuwa ne tare da kulawa da kula da lafiyar yara. Idan yaro ya sami kowane irin mummunan sakamako, ya kamata a daina ciyar da abinci.
Aikace-aikacen aiki mara kyau
Sanya Tagretol ya zama dole bayan tantance aikin koda. Ba'a ba da shawarar yin amfani da miyagun ƙwayoyi a cikin marasa lafiya da keɓaɓɓen lalata koda.
Sanya Tagretol ya zama dole bayan tantance aikin koda.
Amfani don aikin hanta mai rauni
Tarihin cutar hanta dalili ne na taka tsantsan yayin shan ƙwayoyi. Lokaci na kulawa da aikin hanta ya zama dole don guje wa ci gaban cututtukan cututtukan hepatobiliary.
Adadin yawa na Tegretol CR
Sakamakon yawan ƙwayar cuta ta carbamazepine, alamun cututtukan cuta suna faruwa ne a ɓangaren tsarin jijiyoyi, ciwon ciki da aikin zuciya. Amai, tashin zuciya, inhibition na gaba ɗaya suma suna bayyana.
Yawancin bayyanar cututtuka ana dakatar dashi ta hanyar wanke ciki da kuma amfani da bokaye. Ya kamata a gudanar da jiyya a asibiti. Ana nuna wariyar ƙwayar cuta, lura da ayyukan zuciya.
Yin hulɗa tare da wasu kwayoyi
Lokacin da aka haɗa Tegretol tare da wasu jami'ai waɗanda ke canza matakin ayyukan CYP3A4 isoenzyme, haɗuwar carbamazepine a cikin jini yana canzawa. Wannan na iya haifar da raguwa cikin tasiri na jiyya. Irin waɗannan haɗakar magunguna na iya buƙatar daidaita sashi.
Rage maida hankali kan abu mai aiki a hade tare da phenobarbital.
Macrolides, azoles, maganin hana daukar ciki na maganin taiki, magunguna don maganin bacci na iya kara maida hankali kan abubuwan da ke aiki a cikin jini.
Haɗuwa tare da phenobarbital, valproic acid, rifampicin, felbamate, clonazepam, theophylline, da sauransu, suna rage haɗuwa da abu mai aiki.
Gudanarwa na lokaci-lokaci na wasu kwayoyi suna buƙatar daidaitawa don maganin su: maganin tricyclic antidepressants, corticosteroids, protease inhibitors, alluran tashar alli, estrogens, antiviral jamiái, magungunan antifungal.
Haɗuwa tare da wasu diuretics yana haifar da raguwa a cikin ƙwayar plasma na sodium. Carbamazepine na iya rage tasiri na jiyya tare da shakatawa na mara jijiyoyin jiki.
Amfani da ciki tare da maganin hana haifuwa na iya haifar da zubar jini.
Amfani da barasa
Ba'a ba da shawarar cin kowane irin barasa ba yayin amfani da Tegretol.
Analogs
Analogs na wannan kayan aikin sune:
- Finlepsin Retard;
- Finlepsin;
- Carbamazepine.
Ofaya daga cikin analogues na miyagun ƙwayoyi shine Finlepsin Retard.
Bambanci tsakanin Tegretol da Tegretol CR
Wannan magani ya bambanta da daidaitaccen Tegretol a cikin lokacin fitarwa na carbamazepine. Allunan suna da tasirin zamani.
Magunguna kan bar sharuɗan
Magunguna masu sayan magani.
Zan iya siye ba tare da takardar sayan magani ba
A'a.
Farashi
Ya dogara da wurin siye.
Yanayin ajiya na miyagun ƙwayoyi
Dole ne a adana shi a cikin busassun a zazzabi baya wuce + 25 ° C.
Ranar karewa
Amincewa da yanayin ajiya, rayuwar shiryayye shine shekaru 3 daga ranar fitarwa.
Mai masana'anta
Magungunan Novartis Pharma ne suka kera shi.
Nasiha
Artem, 32 years old, Kislovodsk
Tegretol magani ne mai kyau wanda ke taimaka wajan magance jurewa. Na fara shan wannan magani, na sake samun damar yin rayuwa ta yau da kullun. Allunan jimre wa ƙanana da manya. Ban lura da wani sakamako masu illa ba yayin aikace-aikacen. Ina ba da shawara ga duk wanda ke fama da tabin hankali.
Nina, dan shekara 45, Moscow
Anyi amfani da wannan kayan aiki shekara daya da suka gabata. Tsohon tsoffin magungunan rigakafin ya zama abin jaraba, likita ya umurce Tegretol a matsayin wanda zai maye gurbinsa. Na sha allunan kamar mako biyu. Sannan rikitarwa ya bayyana. Ciwon ciki da amai ya bayyana. Yanayina ya kara tabarbarewa, na damu matuka da damuwa. Dole ne in sake komawa wurin likita. Ya yi nazarin. Magungunan sun haifar da halayen cututtukan jini: anemia da thrombocytopenia sun haɓaka. Dole ne in yi sauri na canza maganin.
Cyril, 28 years old, Kursk
Likita ya tsara wannan magani a hade tare da wasu don maganin trigeminal neuralgia. Ban sani ba idan Tegretol ko wasu kwayoyi sun taimaka, amma alamun sun ɓace. Hare-hare na jin zafi sun fara daci da ƙarancin ƙasa. Na sake yin barci kuma na ci abinci na yau da kullun. Zan iya ba da shawarar wannan magani ga duk wanda ya ci karo da irin wannan matsalolin.
