Clopidogrel-Teva magani ne wanda ke hana haɗuwar platelet kuma ya rage tasoshin jijiyoyin jini. Ana amfani da kayan aiki don magani da rigakafin cututtukan zuciya.
Sunan kasa da kasa mai zaman kansa
INN - Clopidogrel.
Clopidogrel-Teva magani ne wanda ke hana haɗuwar platelet kuma ya rage tasoshin jijiyoyin jini.
ATX
Lambar ATX: B01AC04.
Saki siffofin da abun da ke ciki
Maganin yana cikin nau'ikan kwamfyutocin elongated na launin ruwan hoda mai haske. Abubuwan da ke aiki shine hydrosulfate clopidogrel (a cikin adadin 75 MG).
Fitowa:
- lactose monohydrate;
- microcrystalline cellulose;
- hyprolosis;
- crospovidone;
- hydrogenated kayan lambu mai na I;
- sodium lauryl sulfate.
Fim ɗin fim ɗin ya ƙunshi abubuwa masu zuwa:
- lactose monohydrate;
- hypromellose 15 cP;
- titanium dioxide;
- macrogol;
- ja da farin rawaya (daskarar baƙin ƙarfe);
- indigo carmine.
Ana samun magungunan a cikin nau'ikan allunan.
Aikin magunguna
Abubuwan da ke aiki na miyagun ƙwayoyi suna rage haɗin platelet. ADP nucleotides (adenosine diphosphates) suna ƙoƙarin kunna glycoprotein inhibitors kuma suna ɗaure zuwa platelets. A karkashin tasirin clopidogrel, wadannan hanyoyin suna rushewa saboda haka an rage yawan tarin platelet (kungiya). Ayyukan (PDE) na phosphodiesterase bazai canza abu ba.
Sakamakon antiplatelet na miyagun ƙwayoyi yana ɗaukar tsawon rayuwa ta platelet (kimanin kwana 7).
Pharmacokinetics
Lokacin ɗauka ta baka, allunan suna saurin narkewa cikin narkewa. Clopidogrel yana da haɓakar bioavailability, amma ba a canza shi ba shi da tasiri (wannan maganin ne). Yana cikin jini na ɗan gajeren lokaci kuma yana haɗuwa da hanzari a cikin hanta tare da ƙirƙirar metabolites masu aiki da marasa aiki. Sannan Clopidogrel da metabolite mai aiki sun ɗauka kusan sunadarai ga jini.
Sa'a 1 bayan shan miyagun ƙwayoyi a cikin jini, ana lura da mafi girman taro na metabolite marasa ƙarfi na clopidogrel a cikin plasma, wani abu mai mahimmanci na carbonxylic acid, an lura.
An cire maganin a cikin fitsari kuma yana ci gaba cikin kwanaki 5. Ana amfani da metabolite mai aiki a cikin awanni 16.
Alamu don amfani
An wajabta magungunan don hana rikice-rikice na zuciya da jijiyoyin jini a cikin waɗannan lambobin:
- Saukar jini na Myocardial.
- Ischemic bugun jini.
- Cutar sankarar mahaifa ba tare da karuwa ba a bangaren ST.
- Thrombosis (wanda aka yi amfani dashi a hade tare da acid acetylsalicylic acid).
- Karafarini.
- Firamillation na atrial.
- A gaban contraindications don amfanin anticoagulants na kaikaitaccen aiki.
Contraindications
Allunan an haramta shan su zuwa ga marasa lafiya da hanta gazawar (hanya mai tsanani), nuna rashin jinƙai ga miyagun ƙwayoyi ko m zub da jini.
Har ila yau, maganin hana haihuwa shine ciki, lactation da yara 'yan kasa da shekaru 18.
Tare da kulawa
Tare da taka tsantsan, an sanya magungunan don aiki na nakasa (kasawa tare da keɓantar creatinine na 5-15 ml / min), ƙara yawan zubar jini (hematuria, menorrhagia), har ma da bayan aikin tiyata, raunin da ya faru da kuma kasawa a cikin tsarin hemostatic.
A cikin lura da marasa lafiya da cututtukan hanta, ana yin coagulogram akai-akai kuma ana kula da aikin hanta.
Tare da taka tsantsan, an wajabta magunguna don aikin nakasa mai rauni.
Yadda ake ɗaukar clopidogrel-teva?
Marasa lafiya waɗanda suka sami infarction na myocardial infarction an wajabta 75 MG na miyagun ƙwayoyi (1 kwamfutar hannu 1) kowace rana don kwanaki 7-35. Bayan bugun jini, ana shan magungunan a kashi ɗaya, amma hanyar warkewa na iya zuwa watanni shida.
Marasa lafiya da ke fama da cutar sankara mara nauyi ba tare da karuwa ba a bangaren ST ana bada shawarar daukar 300 MG kowace rana a matsayin kashi na farko. Sannan an rage kashi zuwa 75 MG kowace rana, amma ana haɗuwa da maganin antiplatelet tare da acetylsalicylic acid. Ana gudanar da aikin tiyata na shekara 1.
Tare da ciwon sukari
A cikin marasa lafiya da masu ciwon sukari mellitus, ana yawan karuwar haɗarin platelet. Don rigakafin cututtukan cututtukan zuciya da cututtukan zuciya, an wajabta 75 Mittin na clopidogrel-Teva kowace rana.
Tsawon lokacin gudanarwa da yawan insulin ya kamata likita ya tantance shi gwargwadon yanayin mai haƙuri.
Sakamakon sakamako na clopidogrel-Teva
A wani bangare na gabobi
A bango na shan maganin, cututtukan ƙwayar cuta na ciki (na baya da haɗin gwiwa) na iya faruwa.
Daga tsoka da kashin haɗin kai
Rashin tasiri ga tsarin musculoskeletal yana da wuya. Arthritis, arthralgia da myalgia suna yiwuwa.
Magungunan zai iya haifar da ci gaban colitis.
Gastrointestinal fili
Tasirin kan jijiyoyin cikin hanji ya bayyana kamar haka:
- ciwon ciki;
- zub da jini a cikin narkewar abinci;
- tashin zuciya da amai
- zawo
- rauni na raunuka;
- gastritis;
- farashi;
- hepatitis;
- maganin ciwon huhu
- stomatitis
- gazawar hanta.
Hematopoietic gabobin
Daga gefen wannan tsarin ana lura:
- thrombocytopenia;
- leukocytopenia;
- eosinophilia.
Tsarin juyayi na tsakiya
Magungunan a zahiri ba su tasiri da tsarin mai juyayi. A cikin lokuta mafi wuya, ciwon kai, farin ciki, da rikicewa suna faruwa.
Daga tsarin urinary
Sakamakon sakamako daga gabobin urinary:
- hematuria;
- glomerulonephritis;
- ƙãra halittar jini a cikin jini.
Daga tsarin numfashi
Tasiri kan tsarin numfashi:
- hanci;
- na huhun jini;
- bronchospasm;
- cututtukan mahaifa.
Daga tsarin kare jini
Ba a kafa sakamako masu illa ba.
Daga tsarin zuciya
Daga tsarin zuciya da jijiyoyin jini ana lura:
- zub da jini
- jijiyoyin jini;
- vasculitis.
Cutar Al'aura
Wadannan halayen rashin lafiyan na iya faruwa:
- Harshen Quincke na edema;
- magani cutar;
- urticaria;
- itching
A bango daga shan maganin, rashin lafiyan na iya faruwa.
Tasiri kan ikon sarrafa abubuwan inji
Wasu marasa lafiya suna fuskantar ciwon kai da amai yayin shan Clopidogrel-Teva. Yakamata a yi taka tsantsan lokacin sarrafa kayan aiki ko aiwatar da aiki da ke buƙatar mai da hankali sosai.
Umarni na musamman
Kafin tiyata, dole ne a dakatar da maganin (kwanaki 5-7 kafin a yi masa tiyata) saboda yawan haɗarin zub da jini.
Yi amfani da tsufa
Ana amfani da maganin don magance marasa lafiya tsofaffi. Amma a wannan yanayin, ana aiwatar da maganin ba tare da amfani da kashi ba (kashi ɗaya daidai yake da 300 MG) a farkon far.
Adana Clopidogrel-Teva ga yara
An haramta amfani da maganin ga yara 'yan shekara 18.
Yi amfani da lokacin daukar ciki da lactation
Haihuwa da shayarwa sune abubuwan hana amfani da wannan magani.
Ba za ku iya amfani da miyagun ƙwayoyi ba yayin daukar ciki.
Amfani don aikin hanta mai rauni
Marasa lafiya tare da cututtukan hanta (cirrhosis, gazawar hanta) an wajabta maganin tare da taka tsantsan. Don guje wa bashin jini, ya kamata a haɗa magani tare da saka idanu akan aikin hanta.
Clopidogrel-Teva overdose
Tare da gudanar da maganin baka na manyan allurai na miyagun ƙwayoyi (har zuwa 1050 MG), babu wani mummunan sakamako ga jikin.
Amfani na dogon lokaci a cikin manyan allurai na iya haifar da zub da jini.
Yin hulɗa tare da wasu kwayoyi
Saboda haɗarin zub da jini, haramun ne a sha maganin a hade tare da magunguna kamar:
- Anticoagulants.
- Masu hana Glycoprotein IIa / IIIb aiki.
- NSAIDs.
Yakamata a hada shi da heparin.
Ya kamata a haɗakar da hankali tare da thrombolytics da heparin. Tare da yin amfani da lokaci ɗaya tare da omeprazole, esomeprazole da sauran inhibitors na famfo na proton, raguwa a cikin tasirin antiplatelet yana faruwa.
Amfani da barasa
Ba a bada shawarar yin amfani da maganin ba tare da amfani da giya ba. Zai yiwu maye gurbin jiki, ya nuna ta ama, zawo, zazzaɓi, zazzaɓi, gazawar numfashi da bugun zuciya.
Analogs
Shahararrun kwayoyi tare da irin wannan sakamako sune:
- Harshen Lopirel.
- Plavix.
- Sylt.
- Plagril.
- Gabaɗaya.
- Egithromb.
Aiki mai aiki na waɗannan analogues shine clopidogrel.
Magunguna kan bar sharuɗan
Zan iya saya ba tare da takardar sayan magani ba?
Dangane da umarnin, magani yana kan takardar sayen magani.
Farashin Clopidogrel-Teva
Kudin kayan haɗi na allunan 14 jeri daga 290 zuwa 340 rubles, allunan 28 - 600-700 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Ya kamata a aiwatar da ajiya a wuri mai duhu a zazzabi da bai wuce + 25 ° C ba.
Ranar karewa
Magungunan sun dace da shekaru 2.
Mai masana'anta
Mai masana'anta - Teva (Isra'ila).
Ana bayar da maganin ta hanyar sayan magani.
Reviews na clopidogrel-Teva
Irina, ɗan shekara 42, Moscow.
Lokacin da na dauki gwajin jini, sai na sami karin matakan platelet. Likita ya ba da umarnin kashewa. Na dauki miyagun ƙwayoyi na makonni 3, kuma ƙididdigar platelet a cikin jini ya koma al'ada.
Alexander, mai shekara 56, Izhevsk.
Na fara shan wannan magani ne bisa shawarar likita bayan bugun jini. Na kwashe shi tsawon watanni 2 kuma ban yi korafi game da halin da nake ciki ba. Babu sakamako masu illa da suka faru. Magungunan sun cancanci kuɗin.
Leonid, dan shekara 63, Volgograd.
Na yi amfani da wadannan kwayoyin don hana rikice-rikice bayan tiyata. A cikin bayan aikin likita, maganin ya taimaka hana jini kwance. Na yi haƙuri da shigowarsa da kyau; ban taɓa fuskantar mummunan aiki ba.
