An wajabta Gensulin don marasa lafiya da masu ciwon sukari, wadanda suka dace da haɗe tare da wasu nau'ikan insulin. Tare da taka tsantsan, ya kamata a haɗu tare da kwayoyi waɗanda zasu iya haɓaka ko rage tasirin hypoglycemic.
Sunan kasa da kasa mai zaman kansa
Matsalar insulin ɗan adam asalin ilimin ɗan adam.
An wajabta Gensulin don marasa lafiya da masu ciwon sukari, wadanda suka dace da haɗe tare da wasu nau'ikan insulin.
ATX
A10AB01.
Saki siffofin da abun da ke ciki
Kyakkyawan bayani, farin dakatarwa, ana gudanar da subcutaneously. Hazo na iya bayyana wanda zai narke cikin sauƙi lokacin girgiza. An tattara magungunan a cikin kwalabe na milim 10 ko kuma gwal mai nauyin 3 ml.
A cikin 1 ml na miyagun ƙwayoyi, sashi mai aiki yana fitowa a cikin nau'i na insulin na ɗan adam 100 IU. Componentsarin abubuwan haɗin sune glycerol, sodium hydroxide ko hydrochloric acid, metacresol, ruwa mai allura.
A cikin 1 ml na miyagun ƙwayoyi, sashi mai aiki yana fitowa a cikin nau'i na insulin na ɗan adam 100 IU.
Aikin magunguna
Yana nufin insulins na gajere. Ta hanyar amsawa tare da mai karɓa na musamman akan membrane tantanin halitta, yana haɓaka samuwar insulin-receptor complex, wanda yake kunna ayyukan a cikin tantanin halitta da haɗin ginin enzyme.
Matsayi na glucose a cikin jini yana daidaita ta hanyar kara jigilar kaya a cikin sel, ƙara yawan shan abubuwa ta jiki, rage samar da sukari ta hanta, da kuma ƙarfafa glycogenogenesis.
Tsawon lokacin da maganin warkewa ya dogara da:
- kudi sha na aiki mai aiki;
- yanki da kuma hanyar gudanarwa a jiki;
- sashi.
Pharmacokinetics
Bayan allurar da aka bayar ta fara aiki a cikin rabin sa'a, ana yin aikin mafi girman daga awa 2 zuwa 8 kuma zai ɗauki tsawon awanni 10.
Rashin daidaituwa yana faruwa a cikin kyallen takarda, abubuwan da ke aiki ba su wuce zuwa cikin madara ba, kar ƙetare cikin mahaifa, i.e. Karka shafi tayin. Rabin-rayuwar yana ɗaukar mintuna 5-10, waɗanda kodan suka banbaresu da adadinsu ya kai 80%.
Abubuwan da ke aiki na miyagun ƙwayoyi ba su ƙetare mahaifa ba, i.e. Karka shafi tayin.
Alamu don amfani
An nuna shi a cikin lura da waɗannan cututtukan asibiti:
- Type 1 ciwon sukari.
- Nau'in cuta ta II (idan akwai tsayayya da magungunan hypoglycemic).
- Ilimin halin da kansa na ciki
Contraindications
An haramta ta:
- Kowane rashin haƙuri ga mutum aka gyara na miyagun ƙwayoyi.
- Hypoglycemia.
Yadda ake ɗaukar Gensulin?
Ana gudanar da miyagun ƙwayoyi ta hanyoyi da yawa - intramuscular, subcutaneous, intravenous. Zaɓaɓɓen sashi da sashi don allura shine zaɓi daga likitan da ke halartar kowane mara lafiya. Matsakaicin sashi ya bambanta daga 0.5 zuwa 1 IU / kg na nauyin mutum, la'akari da matakin sukari.
Ya kamata a gudanar da insulin rabin sa'a kafin cin abinci ko abun ciye ciye mai haske wanda ya danganta da carbohydrates. Iya warware matsalar preheated zuwa zazzabi dakin. Monotherapy ya ƙunshi allura har zuwa sau 3 a rana (a lokuta na musamman, adadin yana ƙaruwa har sau 6).
Idan kashi na yau da kullun ya wuce 0.6 IU / kg, an kasu kashi da yawa, ana sanya allura a sassa daban-daban na jikin - ƙwararren ƙwaƙwalwar ƙwaƙwalwar zuciya, bangon gaban ciki. Domin kada ya bunkasa lipodystrophy, wurare don injections suna canzawa koyaushe. Ana amfani da sabon allura don kowane allura. Amma game da IM da IV, ana yin shi ne kawai a sashin asibiti daga ma'aikacin lafiya.
Sakamakon sakamako na Gensulin
Tare da cin zarafin kashi da tsarin allura, sakamako masu illa suna haifar ta hanyar:
- rawar jiki
- ciwon kai;
- pallor na fata;
- paresthesia na bakin ciki.
- jin yunwar yau da kullun;
- zafin gumi;
- samarin
Tare da mummunan hypoglycemia, farkon farawar hypoglycemic coma yana yiwuwa.
Daga halayen rashin lafiyan, edewar Quincke, rashes a kan fata, tashin hankali anaphylactic yakan bayyana sau da yawa. Ana nuna halayen gida ta hanyar itching da kumburi, da wuya lipodystrophy, hyperemia ke da wuya. A farkon farawar, wasu marasa lafiya suna fuskantar kurakurai masu raɗaɗi da ke faruwa ba tare da taimakon gaggawa ba.
Tasiri kan ikon sarrafa abubuwan inji
Farkon amfani da insulin ko canzawa zuwa wani nau'in na iya haifar da lalata cikin jin daɗin rayuwa, haɓakar halayen da ba a sani ba. A wannan lokacin, mutum baya buƙatar fitar da abubuwan hawa, abubuwan aiki masu rikitarwa. Zai fi kyau a daina aiki mai haɗari.
Umarni na musamman
Gudanar da maganin ba a yarda da shi ba yayin girgije, ƙirƙirar barbashi mai kauri, ƙarancin launi daban. Yayin duk aikin jiyya, yakamata mai haƙuri ya lura da alamun glucose. Hypoglycemia na faruwa lokacin da:
- yawan abin sama da ya kamata;
- haɓaka aiki na jiki;
- maye gurbin insulin da aka yi amfani da shi;
- amai da gudawa;
- tsallake abinci;
- ƙarancin aikin ƙodan ko hanta, glandar thyroid, adrenal cortex;
- sabon wuri don allura;
- hade tare da wasu kwayoyi.
Rashin ingantaccen magani, rashin magani, musamman idan yazo ga nau'in ciwon sukari na 1, zai haifar da hauhawar jini. Bayyanar cututtuka na haɓaka a hankali kuma suna bayyana tare da yawan urination, kullun ƙishirwa, bushewa da fitar fata, ƙoshin yanayi, kasancewar acetone a cikin iska mai ƙonewa. Idan babu lokacin da ya dace kuma daidai magani, ketoacidosis mai ciwon sukari, ƙwayar cutar hypoglycemic na iya haɓaka.
Ana yin gyaran da kashi ana aiwatar da shi tare da hypopituitarism, cutar Addison, katsewa a cikin glandar thyroid, koda da hanta, cikin tsufa (daga shekaru 65). Sau da yawa, sashi na miyagun ƙwayoyi a cikin marasa lafiya waɗanda ke fuskantar matsanancin ƙoƙarin jiki, suna canza abincinsu kwatsam. Idan mutum ya fara shan wani nau'in magani, za a gudanar da cikakken iko kan adadin glucose.
Insulin yana da matukar yuwuwar yin kuka; sabili da haka, famfon insulin bai kamata a yi amfani dashi ba.
Yi amfani da tsufa
Bayan shekaru 65, ana buƙatar daidaita sutura da ma'auni na yau da kullun na sukari.
Aiki yara
Babu gogewa ta amfani da Gensulin a cikin yara.
Babu gogewa ta amfani da Gensulin a cikin yara.
Yi amfani da lokacin daukar ciki da lactation
Marasa lafiya waɗanda aka gano tare da ciwon sukari na mellitus yayin tsara ciki, gestation na gaba ya kamata su lura da yawan sukari a cikin jini, saboda ƙila kuna buƙatar canza sashi na miyagun ƙwayoyi.
An ba da damar shayar da nono hada tare da amfani da insulin, idan yanayin yarinyar ya kasance mai gamsarwa, babu ciwon ciki. Hakanan ana daidaita yanayin gwargwadon karatun glucose.
Aikace-aikacen aiki mara kyau
Arancin aikin haya shine alamu na kai tsaye don canza adadin maganin da ake sarrafawa.
Amfani don aikin hanta mai rauni
Ana buƙatar magani na daidaitawa na kashi.
Jinnuwar Gensulin
Yin amfani da insulin a adadi mai yawa zai haifar da hypoglycemia. Ana cire digiri mai laushi ta hanyar shan sukari, cin abinci mai kyau na carbohydrate. An ba da shawarar cewa mutane koyaushe suna da abinci mai kyau da abin sha tare da su.
Matsakaici mai zurfi na iya haifar da asarar hankali. A wannan yanayin, ana aiwatar da maganin gaggawa na dextrose iv ga mutum. Bugu da ƙari, ana gudanar da glucagon iv ko s / c. Lokacin da mutum ya zo, yana buƙatar cin isasshen abincin carbohydrate don hana haɗari na biyu.
Matsakaici mai zurfi na iya haifar da asarar hankali.
Yin hulɗa tare da wasu kwayoyi
Akwai jerin magunguna waɗanda zasu iya canza buƙatar insulin na jikin mutum. An inganta tasirin hypoglycemic lokacin da aka yi amfani da su tare:
- maganin haila na baka;
- carbonic anhydrase inhibitors, hanawar kwayoyin hana kwayoyi na oxidase, angiotensin da ke juya masu inzyme;
- sulfonamides;
- Bromocriptine;
- marasa zaɓi na beta-blockers;
- Clofibrate;
- theophylline;
- kwayoyi masu dauke da lithium;
- cyclophosphamide;
- abubuwa a ciki wanda ethanol ke ciki.
Ragewar hypoglycemic yana raguwa yayin ɗauka:
- thiazide diuretics;
- kwayoyin hodar iblis;
- glucocorticosteroids;
- m
- Danazole;
- allunan tashar alli;
- morphine;
- Phenytoin.
Tare da salicylates, duka tasirin wannan maganin yana ƙaruwa kuma yana raguwa.
Amfani da barasa
Yin amfani da insulin lokaci guda tare da abubuwan da ke ƙunshe da giya ba su yarda da su ba.
Analogs
Ana amfani da alamun analog ɗin masu zuwa na maganin: Insuman, Monodar, Farmasulin, Rinsulin, Humulin NPH, Protafan.
Magunguna kan bar sharuɗan
Zan iya saya ba tare da takardar sayan magani ba?
Ba zai yuwu ba. Dogara bisa ga girke-girke.
Farashi
Daga 450 rub.
Yanayin ajiya na miyagun ƙwayoyi
A yanayin zafin jiki daga + 2 ° С zuwa + 8 ° С.
Ranar karewa
Shekaru 2
Mai masana'anta
BIOTON S.A. (BIOTON S.A.), Poland.
Insuman shine misalin maganin.
Nasiha
Ekaterina dan shekara 46, Kaluga
Na kasance ina amfani da Gensulin R tsawon shekaru. A gabansa na gwada magunguna da yawa waɗanda basu dace ba. Kuma wannan ya dace kuma an yarda da shi sosai. Ina son gaskiyar cewa kwalban buɗewa an adana shi daidai, magani ba ya rasa tasiri. Tasirin sa ya daɗe.
Sergey 32 years old, Moscow
Lokacin da aka tsara miyagun ƙwayoyi, na ji tsoro sosai game da sakamako masu illa, amma a banza. Na shigar da shi, kamar yadda aka tsara a cikin umarnin ta amfani da alƙalami mai siket. Gensulin M30 a farkon jiyya ya haifar da tsananin zafin lokaci, amma komai ya ɓace bayan mako biyu. Ina jin dadi, sukari ya ci gaba.
Inga shekara 52, Saratov
Na yi tsammanin mummunan sakamako daga miyagun ƙwayoyi, amma ya zama kyakkyawa. Mai girma don amfani biyu, hadewar magani. Ba a taɓa bayyana yanayin rashin lafiyar ba, kodayake mutane da yawa suna rashes a kan fata a farkon aikace-aikacen Gensulin N.
