Cutar sankarau, saboda saurin saurin girma da kuma yiwuwar mutuwa, yana haifar da babbar barazana ga bil'adama. A cikin shekaru 20 da suka gabata, ciwon sukari ya shiga cikin manyan abubuwanda ke haifar da mace-mace. Ba abin mamaki bane cewa cutar ta ƙunshi wasu manyan fifiko da aka sanya wa likitoci a duk duniya.
Hanyar sashi na magani
Magunguna na Metformin-mawadaci tare da babban kayan aiki na metformin hydrochloride ana samarwa ta cikin masana'antar cikin gida a cikin kashi biyu: 500 MG ko 850 MG kowane. Baya ga kayan aikin na yau da kullun, akwai kuma maɗaukaki a cikin abun da ke ciki: Opadry II, silicon dioxide, magnesium stearate, copovidone, cellulose, polyvidone.
Ana iya gano maganin ta hanyar alamun halayyar: zagaye (500 MG) ko m (850 MG) convex farin Allunan a cikin kwasfa suna haɗe a cikin sel mai laushi na 10. A cikin akwatin zaka iya samun daga 1 zuwa 6 irin faranti. Kuna iya samun magani kawai ta takardar sayan magani.. A kan Metformin Richter, farashin 60 Allunan na 500 MG ko 850 MG shine 200 ko 250 rubles. daidai da. Mai sana'ar ya iyakance rayuwar shiryayye zuwa shekaru 3.
Hanyar aiwatar da maganin
Metformin Richter yana cikin rukuni na biguanides. Sinadarin sa na yau da kullun, metformin, lowers glycemia ba tare da tayar da hanji ba, don haka babu rashin lafiyar jiki a cikin illarsa.
Metformin-mai-arziki yana da kayan aikin sau uku na maganin antidiabetic.
- Magungunan ta hanyar 30% yana hana samar da glucogen a cikin hanta ta hanyar hana glucogenesis da glycogenolysis.
- Magungunan yana hana shan gulukos ta jikin bangon hanji, don haka carbohydrates wani bangare ya shiga cikin jini. Shan magungunan kada ta zama dalilin hana abinci mai karancin abinci.
- Biguanide yana rage juriya daga sel zuwa glucose, yana haɓaka amfani da shi (har zuwa babban adadin a cikin tsokoki, ƙasa a cikin mai mai).
Magungunan yana inganta haɓakar lipid na jini: ta hanzarta dawo da halayen, yana hana samar da triglycerol, da kuma janar da "marasa kyau" (ƙarancin yawa) nau'ikan cholesterol, da rage rage juriya na masu karɓa.
Tunda metformin baya tasiri β-sel na kayan islet da ke da alhakin samar da insulin kwayoyin halitta, wannan ba ya haifar da lalacewarsu da kuma necrosis.
Ba kamar madadin magungunan hana haihuwa ba, yawan yin amfani da miyagun ƙwayoyi yana ba da ƙarfin daidaitawa. Wannan gaskiyar tana da mahimmanci ga yawancin masu ciwon sukari, tun da nau'in ciwon sukari nau'in 2 yawanci yana tare da kiba, wanda ke rikitar da aikin glycemia sosai.
Yana da tasiri na biguanide da fibrinolytic, wanda aka samo asali daga hanawar ƙwayar plasminogen nama mai hanawa.
Daga cikin jijiyoyin mahaifa, wakili na baki yana shafar jiki gaba daya tare da bioavailability har zuwa 60%. An lura da gangar jikinsa bayan kimanin awa 2.5. Ana rarraba magungunan ba tare da bambanci ba akan gabobin da tsarin: mafi yawansu yana tarawa a cikin hanta, hujin parenchyma, tsokoki, da gyada mai narkewa.
Thea'idodin metabolite ana cire su ta hanyar ƙodan (70%) da hanjinsu (30%), kawar rabin rayuwa yana da bambanci daga 1,5 zuwa 4.5 hours.
Wanene aka nuna masa maganin
An tsara Metformin-richter don gudanar da ciwon sukari na nau'in 2, duka biyu a matsayin magani na farko da kuma a wasu matakai na cutar, idan gyare-gyare na rayuwa (ƙarancin abinci mai narkewa, ƙwarewar yanayin motsin rai da aikin jiki) ba zai samar da cikakkiyar iko na glycemic ba. Magungunan sun dace da monotherapy, ana kuma amfani dashi a cikin magani mai wahala.
M cutar daga miyagun ƙwayoyi
Allunan suna contraindicated ga mutane tare da rashin kwanciyar hankali ga sinadaran da dabara. Bugu da kari, ba'a ba da umarnin Metformin Richter ba:
- Tare da decompensated renal da hanta dysfunctions;
- Masu ciwon sukari tare da matsanancin ciwon zuciya da gazawar numfashi;
- Iyaye masu juna biyu da masu shayarwa;
- Barasa giya da wadanda ke fama da mummunan guba;
- Marasa lafiya a cikin yanayin lactic acidosis;
- A lokacin tiyata, lura da raunin da ya faru, ƙonewa;
- A lokacin karatun radioisotope da radiopaque;
- A cikin lokacin farfadowa bayan infarction myocardial;
- Tare da rage yawan abinci da kuma aikin motsa jiki.
Shawarwarin don amfani
Likita ya gabatar da tsarin kulawa da kowane mai ciwon sukari daban-daban, yin la’akari da bayanan dakin gwaje-gwaje, matakin ci gaban cutar, hadewar rikice-rikice, shekaru, amsawar mutum ga maganin.
Don Metformin Richter, umarnin don amfani yana ba da shawarar cewa ka fara hanya tare da mafi ƙarancin adadin 500 MG tare da ƙayyadaddun matakai na kashi tare da isasshen tasiri a kowane sati 2. Matsakaicin ƙa'idar da miyagun ƙwayoyi shine 2.5 g / rana. Ga masu fama da cutar siga, waɗanda sau da yawa suna da matsalolin koda, matsakaicin kashi shine 1 g / day.
Lokacin canzawa zuwa Metformin Richter daga wasu allunan rage sukari, daidaitaccen matakin farko shine 500 MG / rana. Yayin ƙirƙirar sabon tsarin, su ma suna jagorantar su da jimlar magungunan da suka gabata.
A likita ne m da likita, tare da al'ada dauki na jiki, da miyagun ƙwayoyi masu ciwon sukari an dauki rayuwa.
Kimantawa da miyagun ƙwayoyi ta likitoci da masu ciwon sukari
Game da Metformin Richter, sake dubawa suna hade. Likitocin da masu ciwon sukari sun lura da babban tasirin maganin: yana taimakawa wajen sarrafa sukari da ci, babu wani nau'in maye, ƙaramar sakamako, sakamako mai kyau na cututtukan zuciya da sauran rikice-rikice.
Mutanen da ke da ƙoshin lafiya da ke yin gwaji tare da ƙwayar don asarar nauyi sun fi yin gunaguni game da tasirin da ba a so. Shawarwarin gyaran ƙirar wannan rukuni na marasa lafiya yakamata ya kamata mai ƙwararren masanin abinci ya ƙawata, kuma ba masu kutse cikin yanar gizo ba.
Ba wai kawai endocrinologists suna aiki tare da metformin ba, har ma da likitocin zuciya, masu ilimin hanyoyin kwantar da hankali, likitan jiki, likitan mata, kuma bita mai zuwa wani tabbaci ne na wannan.
Irina, ɗan shekara 27, St. Petersburg. A cikin tattaunawar dandamali, Metformin Richter shine mafi yawan tattaunawar masu ciwon sukari ko 'yan wasa, kuma na sha shi don samun juna biyu. Na kasance cikina na polycystic ovary, wanda likitoci suka kira dalilin rashin haihuwa, na kusan shekaru 5. Babu Progesterone (injections) ko magungunan hormonal da suka taimaka don motsa matsalar, har ma sun ba da laparoscopy don haifar da ƙwayoyin ƙwayoyin cuta. Lokacin da nake shirya gwaje-gwaje da kuma kula da asma - wata babbar matsala ga aikin, likitan ilimin mahaifa daya ya shawarce ni in gwada Metformin Richter. A hankali, sake zagayowar ya fara murmurewa, kuma lokacin da watanni shida daga baya akwai alamun ciki, ban yi imani ko dai gwajin ko likitoci ba! Na yi imani cewa wadannan kwayoyin sun kubutar da ni, a cikin matsananciyar shawara na ba ku shawara ku yi kokarin gwadawa, kawai ku yarda da likitan likitan mata don jigilar ci.
Yawan sha da yawa gefen jiki
Ko da ƙaruwa sau goma a cikin adadin metformin waɗanda masu sa kai suka karɓa a gwaji na asibiti ba su tsokani da cutar tarin fatar jini ba. Madadin haka, lactic acidosis ya haɓaka. Kuna iya gane yanayi mai haɗari ta hanyar tsoka da raɗaɗi, rage zafin jiki, rashin lafiyar dyspeptik, asarar daidaituwa, fitsarar nama zuwa ga biri.
Wanda aka cutar ya bukaci asibiti da gaggawa. A wani asibiti, ana cire ragowar metabolite ta hanyar hemodialysis, kuma ana gudanar da aikin tiyata ta kwakwalwa tare da saka idanu kan ayyukan duk mahimman sassan jikin.
Abubuwan da ke aiki da metformin hydrochloride suna da tushe na shaida don aminci. Amma wannan ya shafi, da farko, ga Glucophage na asali. Jenerics sun ɗan bambanta a cikin kayan haɗin kai, ba a gudanar da babban nazari game da ingancin su ba, sabili da haka ana iya bayyana sakamakon.
Kimanin rabin masu ciwon sukari suna koka da rashin lafiyar dyspeptik, musamman a lokacin daidaitawar. Idan kun daidaita sashi a hankali, ku sha miyagun ƙwayoyi tare da abinci, tashin zuciya, za a iya guje wa ɗanɗano na baƙin ƙarfe da alaƙa. Abun da ke cikin abincin shima yana taka muhimmiyar rawa: amsawar metformin kuma jiki yayi daidai ga kayan furotin (nama, kifi, madara, ƙwai, namomin kaza, kayan lambu).
Taya zan iya maye gurbin Metformin-richter
Don magani na Metformin Richter, analogues na iya zama ko dai Allunan tare da ainihin kayan haɗin, metformin hydrochloride, ko madadin magungunan hypoglycemic tare da sakamako iri ɗaya:
- Glucophage;
- Glyformin;
- Metfogamma;
- NovoFormin;
- Metformin-Teva;
- Bagomet;
- Diaformin OD;
- Metformin Zentiva;
- Tsarin Pliva;
- Metformin-Canon;
- Glyminfor;
- Siofor;
- Methadiene.
Baya ga analogues tare da saurin sakin jiki, akwai allunan da ke da tasiri na tsawon lokaci, tare kuma da haɗuwa da abubuwa da yawa masu aiki a cikin dabara guda. Zaɓuɓɓukan ƙwayoyi masu yawa, har ma ga likitoci, ba koyaushe yana ba ku damar zaɓar sauyawa da magani ba, kuma gwaji tare da lafiyar ku game da kanku shiri ne na hallaka kai.
Aikin mai ciwon sukari shine a taimaka wajan yin aikin ƙwaƙwalwar har zuwa iyakar ƙarfinsa, tunda ba tare da gyaran salon ba, duk shawarwarin sun rasa ƙarfi.
Shawarar Farfesa E. Malysheva ga duk waɗanda likitan ya umarta metformin, akan madaidaiciya
