Glucovans - umarnin, musanyawa da sake dubawa na masu haƙuri

Glucovans shiri ne mai kashi biyu wanda ya kunshi magungunan rage yawan sukari guda biyu, glibenclamide da metformin. Duk abubuwan biyu sun nuna amincin su da inganci a cikin binciken da yawa. An tabbatar da cewa ba wai kawai suna daidaita glucose bane kawai, amma suna rage hadarin cututtukan angiopathic da kuma tsawanta rayuwar mai haƙuri.

Haɗin metformin da glibenclamide suna yaɗu. Koyaya, Glucovans na iya, ba tare da ƙari ba, a kira shi magani na musamman wanda ba shi da analogues, tunda glibenclamide yana cikin yanayi na musamman, micronized a ciki, wanda ke rage haɗarin cutar hawan jini. Ana yin allunan Glucovans a Faransa ta Merck Sante.

Dalilai na nadin glucovans

Rage hawa da ci gaban rikice-rikice a cikin masu ciwon sukari yana yiwuwa ne ta hanyar tsawan kula da ciwon suga. Lambobin neman biyan diyya sun yi tsauri a shekarun baya-bayan nan. Wannan ya faru ne saboda gaskiyar cewa likitocin sun dakatar da yin la’akari da nau'in ciwon sukari na 2 na cuta mai sauƙi fiye da nau'in 1. An tabbatar da cewa wannan mummunan cuta ne, mai saurin tashin hankali, ci gaba wanda ke buƙatar magani koyaushe.

Don cimma daidaituwar glycemia na yau da kullun, sau da yawa yana buƙatar ƙwayar sukari fiye da ɗaya. Tsarin kula da hadaddun hanya abu ne gama gari ga yawancin masu ciwon sukari tare da gogewa. A matsayinka na babban doka, ana kara sabon allunan da zaran wadanda suka gabata ba su samar da kashi daya na cutar haemoglobin. Magungunan farko-farko a duk ƙasashen duniya suna metformin. Abubuwan da aka samo na sulfonylureas yawanci ana kara dasu a ciki, mafi mashahuri wanda shine glibenclamide. Glucovans haɗuwa ne da waɗannan abubuwa guda biyu, yana ba ku damar sauƙaƙe tsarin kulawa don masu ciwon sukari, ba tare da rage tasiri ba.

Glucovans tare da ciwon sukari an wajabta:

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

1. Idan akwai alamun jinkirta cutar ko kuma hanzartawa, saurin ɓarna. Mai nuna alama cewa metformin kadai ba zai isa ya sarrafa ciwon sukari ba kuma ana buƙatar Glucovans - glucose mai azumi fiye da 9.3.
2. Idan a matakin farko na maganin ciwon sukari yana maganin karancin abinci mai narkewa a jiki, motsa jiki da metformin basa rage haemoglobin da ke ƙasa da 8%.
3. Tare da raguwa a cikin samar da insulin na kansa. Wannan nuni ko dai an tabbatar da dakin gwaje-gwaje ko kuma shawarar da aka danganta da karuwar cutar glycemia.
4. Tare da ƙarancin haƙuri na metformin, wanda ke ƙaruwa lokaci guda tare da karuwa a cikin sashi.
5. Idan metformin a cikin babban allurai yana contraindicated.
6. Lokacin da mai haƙuri ya samu nasarar ɗaukar metformin da glibenclamide kuma yana son rage adadin allunan.

Aikin magunguna

Magungunan Glucovans shine haɗin ƙayyadaddun haɗakar wakilai guda biyu tare da tasirin sakamako masu yawa.

Metformin yana rage glucose na jini ta hanyar kara yawan jijiyoyi, mai, hanta zuwa cikin insulin. Yana shafar matakin haɗin hormone kawai ba kai tsaye: aikin ƙwayoyin beta suna inganta tare da daidaituwa na abubuwan haɗin jini. Hakanan, ƙwayoyin metformin Glucovans suna rage yawan samar da glucose ta hanta (tare da nau'in ciwon sukari na 2, yana sau 2-3 sau da yawa fiye da al'ada), yana rage rage yawan glucose daga ƙwayar gastrointestinal cikin jini, yana daidaita lipids na jini, kuma yana taimakawa rage nauyi.

Glibenclamide, kamar duk abubuwan da aka samo na sulfonylurea (PSM), suna da tasirin kai tsaye akan ɓoye insulin ta hanyar ɗaura wa masu karɓa na beta-cell. Tasirin maganin yana da ƙanƙan da yawa: saboda haɓaka da yaduwar insulin a cikin jini da raguwar tasirin gllu a cikin kyallen takarda, yin amfani da glucose yana inganta, kuma hantarsa ​​ta hana shi. Glibenclamide shine magani mafi karfi a cikin kungiyar PSM; anyi amfani dashi a aikace-aikacen asibiti sama da shekaru 40. A yanzu likitocin sun fi son sabbin hanyoyin samar da microlized na glibenclamide, wanda shine bangare na Glucovans.

Amfaninta:

• yana aiki sosai fiye da yadda aka saba, wanda ke ba da damar rage kashi na maganin;
• glibenclamide barbashi a cikin matrix na kwamfutar hannu suna da 4 girma dabam. Suna narkewa a lokuta daban-daban, don haka inganta haɓakar miyagun ƙwayoyi zuwa cikin jini da rage haɗarin hauhawar jini;
• ƙananan ƙananan glibenclamide daga Glucovans suna haɗuwa da hanzari zuwa cikin jini kuma suna rayayye rage glycemia a cikin sa'o'i na farko bayan cin abinci.

Haɗin abubuwa guda biyu a cikin kwamfutar hannu guda ɗaya baya lalata tasirin su. Akasin haka, binciken ya samo bayanai a madadin Glucovans. Bayan canjawar masu ciwon sukari shan metformin da glibenclamide zuwa Glucovans, haemoglobin ya ragu da matsakaicin 0.6% na watanni shida na magani.

A cewar masu kera, Glucovans ita ce shahararrun magunguna biyu na duniya, an yarda da amfani da shi a cikin kasashe 87.

Yadda ake shan magani yayin jiyya

Magungunan Glukovans an samar da su a cikin juzu'i biyu, saboda haka zaka iya zaɓar madaidaicin kashi a farkon kuma ƙara shi a gaba. Alamar a kan fakitin 2.5 MG + 500 MG ta ba da shawarar cewa an sanya microlized glibenclamide 2.5 a cikin kwamfutar hannu, metformin 500 mg. Ana nuna wannan maganin a farkon magani ta amfani da PSM. Ana buƙatar zaɓi 5 MG + 500 MG don ƙara ƙarfin jiyya. Ga marasa lafiya da hyperglycemia ke karbar ingantaccen kashi na metformin (2000 mg a kowace rana), ana nuna karuwa a cikin yawan ƙwayar glibenclamide don sarrafa ciwon sukari mellitus.

Shawarwarin maganin Glucovans daga umarnin don amfani:

1. Yawan farawa a mafi yawan lokuta shine 2.5 mg + 500 MG. Ana ɗaukar maganin tare da abinci, wanda yakamata ya zama carbohydrates.
2. Idan a baya wani nau'in mai ciwon sukari guda biyu ya ɗauki kayan aiki guda biyu a cikin allurai masu ƙarfi, farawa na iya zama mafi girma: sau biyu 2.5 mg / 500 mg. A cewar masu ciwon sukari, glibenclamide a matsayin wani ɓangare na Glucovans yana da ingantaccen aiki fiye da yadda aka saba, sabili da haka kashi na baya na iya haifar da hypoglycemia.
3. Daidaita sashi bayan sati 2. Abin da ya fi muni a haƙuri da ke dauke da ciwon sukari yana haƙuri da magani tare da metformin, tsawon lokacin da koyarwar ke ba da shawarar barin ta don yin amfani da miyagun ƙwayoyi. Increasearar haɓaka mai sauri na iya haifar ba kawai ga matsaloli tare da ƙwayar gastrointestinal ba, har ma da raguwar glucose jini.
4. Matsakaicin sashi shine 20 MG na micronized glibenclamide, 3000 MG na metformin. A cikin sharuddan Allunan: 2.5 MG / 500 MG - guda 6, 5 MG / 500 MG - 4 guda.

Shawarwarin daga umarnin shan allunan:

Side effects

Bayani daga umarnin don amfani da tasirin tasirin sakamako:

Dangane da sake dubawa, manyan matsaloli ga marasa lafiya da ke shan miyagun ƙwayoyi Glukovans, suna haifar da rashin jin daɗi a cikin narkewa. Za a iya hana su kawai da ƙaruwa sosai a cikin ƙaruwa da kuma amfani da Allunan ta musamman tare da abinci.

A cikin masu ciwon sukari, yawanci mai saurin rashin ƙarfi yana faruwa. Ana cire shi da sauri ta hanyar glucose kai tsaye bayan farkon bayyanar cututtuka. Ga marasa lafiya waɗanda ba su ji raguwar sukari ba, umarnin ba da shawarar ɗaukar allunan Glucovans da analogues na rukuni. Ya nuna haɗarin metformin tare da gliptins: Galvus Met ko Yanumet.

Contraindications

Amfani da Glucovans yana da haɗari ga masu ciwon sukari waɗanda ke da contraindications zuwa metformin ko glibenclamide:

• rashin lafiyan halayen ga metformin ko kowane PSM;
• Nau'in nau'in ciwon sukari na 1;
• cututtukan koda, idan creatinine> 110 mmol / l a cikin mata,> 135 a cikin maza;
• idan akwai cututtukan m, ana tambayar likita game da yiwuwar yin amfani da maganin a cikin mai haƙuri.
• ciki, lactation;
• ketoacidosis, lactic acidosis;
• hali zuwa lactic acidosis, babban haɗarinsa;
• abinci mai karancin kalori mai tsawo (<1000 kcal / day);
• shan magunguna waɗanda, haɗe tare da Glucovans, suna ba da gudummawa ga ci gaban hypoglycemia. Mafi haɗarin ƙwayoyin antifungal. Za'a iya amfani da magungunan da ke shafar glycemia (cikakken jerin a cikin umarnin takarda) lokaci guda tare da Glucovans bayan daidaitawa na kashi.

Me za a iya maye gurbinsa

Glucovans bashi da cikakkun analogues, tunda duk sauran magungunan da aka yiwa rajista a Rasha tare da abun guda ɗaya sun ƙunshi glibenclamide na yau da kullun, kuma ba micronized ba. Tare da babban yiwuwar za su ɗan yi ƙasa da Glucovans, don haka dole ne a ƙara yawan adadin su.

Hada magungunan metformin + talakawa na glibenclamide sune Glibenfage; Gluconorm da Gluconorm Plus; Metglib da karfi na Metglib; Glibomet; Bagomet Plus.

Glucovans kungiyar analogues sune Amaril M da Glimecomb. Anyi la'akari da su na zamani fiye da magunguna na sama kuma wataƙila suna haifar da hypoglycemia.

Yau, DPP4 inhibitors (glyptins) da haɗuwarsu da metformin - Yanuviya da Yanumet, Galvus da Galvus Met, Ongliza da Combogliz Prolong, Trazhenta da Gentadueto - suna karuwa sosai. Su, kamar Glucovans, suna haɓaka aikin insulin, amma kar a haifar da rashin lafiyar hypoglycemia. Wadannan kwayoyi ba su da mashahuri kamar Glucovans saboda farashin su mai girma. Kudaden tattarawa na wata-wata daga 1,500 rubles.

Glucovans ko Glucophage - wanda yafi kyau

Magungunan Glucofage ya ƙunshi metformin kawai, saboda haka, wannan magani zai zama mai tasiri kawai a farkon matakin cutar sankara, lokacin da insulin kira har yanzu ya isa ya daidaita glycemia. Magunguna ba zai iya hana lalacewar ƙwayoyin beta a cikin nau'in ciwon sukari na 2 ba. A cikin masu ciwon sukari, wannan tsari yana ɗaukar lokaci daban, daga shekaru 5 zuwa shekarun da suka gabata. Da zaran karancin insulin ya zama mai mahimmanci, Glucophage kadai ba za'a iya watsa shi da shi ba, koda kuwa an sha shi da yawa. A halin yanzu, an ba da shawarar fara shan Glucovans lokacin da 2000 mg na Glucophage ba su samar da sukari na al'ada ba.

Yanayin ajiya da farashin

Farashin ƙananan sashi na Glucovans - daga 215 rubles., Mafi girma - daga 300 rubles., A cikin fakitin 30 Allunan. Haɗin shirye-shiryen Rasha tare da glibenclamide farashin kusan 200 rubles. Farashin Amaril kusan 800, Glimecomb - kusan 500 rubles.

Ana adana Glucovans har tsawon shekaru 3. Dangane da umarnin, ya kamata a kiyaye allunan a zazzabi a ƙasa da 30 ° C.

Nazarin masu ciwon sukari