Glycohemoglobin jigon jini ne wanda ke nuna matsayin sukari na jini (glycemia) a wani lokaci. Wannan alamar tana haɗuwa da haemoglobin da glucose. Alamar tana ƙayyade matakin haemoglobin a cikin jini, wanda yake da alaƙa da ƙwayoyin sukari.
Eterayyade matakin glycated haemoglobin yana da mahimmanci ga mata, saboda godiya ga wannan alamar, ana iya gano cutar sankara a matakin farko. Saboda haka, jiyya zai kasance cikin lokaci kuma mai inganci.
Hakanan, ana yin bincike don tantance ƙididdigar a cikin jini don tsari don kimanta ƙimar maganin cutar ciwon sukari. An tantance digirin ne ta hanyar adadin haemoglobin cikin kashi.
(Hb A1)
Haemoglobin mai narkewa yana bayyana saboda hulɗar amino acid tare da sukari, kodayake enzymes ba su da hannu a cikin aikin. Don haka, glucose da amino acid suna hulɗa, suna samar da haɗin gwiwa - glycohemoglobin.
Saurin daukar wannan yanayin da adadin haemoglobin da aka samu ana tantance shi da matsakaicin taro na sukari a cikin jini yayin aikin tantanin jini. Sakamakon haka, ana samar da nau'ikan nau'ikan tarin bayanai: HLA1a, HLA1c, HLA1b.
Kowa ya san cewa tare da wata cuta kamar su cutar sankara, matakan glucose na jini suna ƙaruwa. Dangane da wannan, tsarin fushin glucose da kwayoyin haemoglobin a cikin mata yana kara saurin habaka su. Sakamakon haka, ƙarar ta karu.
Ana samun haemoglobin da ke cikin jini a sel masu launin ja (ƙwayoyin jini). Tsawon rayuwarsu kusan kwanaki 120 ne. Don haka, bincike don tantance taro na haemoglobin zai iya nuna matsayin glycemia a cikin dogon lokaci (kimanin kwanaki 90).
Kula! Kwayoyin jini suna da rai tsawon rai, saboda haka suna riƙe da ƙwaƙwalwar ƙwayar haemoglobin da ya haɗu da glucose.
Daga duk abin da ke sama, tambaya mai ma'ana ta taso: me yasa ba a tantance lokacin glycemia da tsawon rayuwar ƙwayoyin jan jini ba? A zahirin gaskiya, shekarun kwayoyin halittar jan jini na iya zama daban, saboda wadannan dalilai, idan aka yi la’akari da tsammanin rayuwarsu, kwararru sun tsayar da kusan shekarun kwanaki 60 zuwa 90.
Gudanar da ciwon sukari
Ana samun gemocosylated haemoglobin a cikin jinin marasa lafiya da mata masu lafiya da maza. Koyaya, a cikin masu ciwon sukari, ana iya ƙara ƙididdigar jini, wanda ke nufin cewa ƙimar ta wuce sau 2-3.
Lokacin da aka sake dawo da matsayin al'ada na glucose a cikin jini, maida hankali na glycogemoglobin zai sake komawa cikin makonni 4-6, sakamakon abin da dabi'un shi ma ke inganta.
Yin nazari don ƙididdigar haɓaka ya sa ya yiwu a ƙayyade tasiri na lura da ciwon sukari. Yawancin lokaci ana amfani da glycosylated hemoglobin gwajin don kimanta tasirin maganin cutar siga a cikin mata a cikin watanni 3 da suka gabata.
Kula! Idan adadi ya karu, domin dawo da ka’idarsa, ya zama dole a yi gyara don magance cutar.
Kuma ga mata da maza, ana amfani da manuniyar azaman alamar hadari wacce ke yanke hukunci game da yiwuwar cutar. Morearin yawan ƙwayar glycogemoglobin yana ƙaruwa, ƙarin glycemia zai kasance cikin kwanaki 90 na ƙarshe. Don haka, hadarin kamuwa da cutar kansa yana ƙaruwa sosai.
An tabbatar da cewa raguwar kawai 10% yana taimakawa rage yiwuwar kamuwa da ciwon sukari (makanta) da kusan kashi 50%.
Madadin gwajin glucose
A yau, don gano ciwon sukari, za a yi amfani da bincike don auna adadin glucose a cikin jini kuma za a yi nazarin haƙuri kan haƙuri. Amma duk da haka, yuwuwar rashin gano cutar sankara, koda lokacin da aka gudanar da binciken, ya wanzu.
Gaskiyar ita ce maida hankali a cikin glucose alama ce mara tabbatacciya, saboda tsarin sukari na bazata zai iya haɓaka ko ya ragu sosai. Sabili da haka, hadarin da bincike zai zama ba abin dogaro bane har yanzu ya kasance.
Hakanan, gwaji don tantance glucose a cikin jini ya nuna cewa an rage yawanta ko an karɓa kawai lokacin bincike.
Ba a yin amfani da binciken ƙididdiga ba sau da yawa kamar gwajin glucose na jini. Wannan saboda kimantawar haemoglobin yana da tsada sosai. Bugu da ƙari, haemoglobinopathy da anemia na iya nunawa a cikin tattarawar jigon, saboda wanda sakamakon zai kasance ba daidai ba.
Hakanan, sakamakon binciken a cikin yanayi daban-daban waɗanda ke shafar rayuwar rayuwar ƙwayoyin jan jini na iya bambanta.
Kula! Zubda jini ko zub da jini na iya canza sakamakon gwajin haemoglobin.
WHO ta bada shawarar sosai a dauki gwajin haemoglobin na gwajin cutar sankara. Masu ciwon sukari yakamata su gwada glycogemoglobin akalla sau 3 a wata.
Hanyoyi don auna glycogemoglobin
Matsayin hemoglobin na glycosylated na iya bambanta dangane da hanyoyin da wani ɗakin bincike ke amfani da shi. A wannan batun, ana yin gwajin ciwon sukari mafi kyau a cikin cibiyoyi guda ɗaya saboda sakamakon ya kasance daidai.
Kula! Jini don nazarin matakin glycogemoglobin dole ne a ɗora akan komai a ciki kuma ba a son yin gwaji bayan zubar jini da zubar jini.
Dabi'u
Ka'idodin glycogemoglobin shine 4.5-6.5% na jimlar haemoglobin. Hemoglobin maɗaukaki na iya nuna:
- rashin ƙarfe;
- ciwon sukari mellitus.
HbA1, yana farawa daga 5.5% kuma ya karu zuwa 7%, yana nuna kasancewar ciwon sukari mellitus (nau'in 2).
HbA1 yana farawa daga 6.5 da haɓaka zuwa 6.9% na iya nuna yiwuwar kamuwa da ciwon sukari, kodayake gwajin glucose na iya zama al'ada.
Levelsarancin glycogemoglobin suna ba da gudummawa ga:
- zub da jini ko zub da jini;
- hawan jini;
- yawan haila.
