Yin magani na ciwon sukari na type 2 yana da tsawo kuma yana buƙatar amfani da magunguna na musamman. Zabi na kwayoyi ya dogara ba kawai da tsananin cutar ba, har ma a kan yanayin mutum na haƙuri, halayen jikinsa, kasancewar ƙarin cututtuka.
Maganin Metformin na maganin cututtukan type 2 shine ɗayan da aka fi amfani dashi shekaru da yawa. Wannan asalin abubuwa ne na biguanides (wani rukuni na sunadarai da ke tattare da wucin gadi wanda ke da tasirin gaske), warkewar cututtukan da ke haifar da raguwar glucose na jini da sakamako na warkewa. Kamar yadda ka sani, nau'in ciwon sukari na 2 shine insulin. Wannan yana nufin cewa akwai hanyoyi biyu don maganin ta - rage matakan sukari na jini da karfafa ƙarin samar da insulin. Yin amfani da metformin ga masu ciwon sukari yana ba ku damar kwantar da matakin glucose. Yi la'akari da manyan fa'idodi da rashin amfanin wannan magani.
Ka'idar Metformin
Abunda yake aiki shine metformin hydrochloride. Daga aji na biguanides, shi kaɗai ne yake da ingantaccen sakamako na warkewa.Nazarin masu haƙuri suna ba da shawarar cewa wannan maganin yana aiki fiye da sauran masu yawa a cikin aji. Wannan shi ne saboda gaskiyar cewa yana aiki a matakin salula, yana ƙaruwa da hankalinsu ga insulin. Godiya ga aikin Metformin, ana lura da sakamako masu zuwa:
- hanta tana yin karancin glucose;
- karin kitse mai yawa yana fara amfani da oxidize;
- sel sun zama masu saukin kamuwa da insulin;
- ƙarancin glucose yana cikin ƙananan hanji.
- tsokoki suna fara cinye ƙarin glucose;
- wani ɓangare na glucose yayin narkewa ya juya zuwa lactate (lactic acid).
Don haka, maganin yana rage sukarin jini a wata hanya kai tsaye, tunda babban tasirin sa shine ƙara haɓaka jikin mutum ga insulin.
Sakamakon gaskiyar cewa maganin yana motsa hadawan abu na iskar shaka mai guba, ƙarin tasirin warkewa yana bayyana, yana faɗaɗa rukuni na waɗanda aka ba da shawarar su sha Metformin. Waɗannan sune kamar haka:
- da samuwar atherosclerotic jijiyoyin bugun jini ya tsaya;
- nauyin jikin mutum yana raguwa, wanda hakan yana tasiri sosai wajen magance cutar sikari;
- saukar karfin jini.
Ya kamata a lura cewa aiwatar da hada hada abubuwa da abubuwa masu guba a cikin lalacewarsu da canzawa zuwa makamashi. Don haka, yawan ajiyar kitse ya ragu, jiki zai zama siririn. Sabili da haka, ana yawan amfani da miyagun ƙwayoyi don asarar nauyi, saboda yana motsa ƙone mai kai tsaye.
Rashin mummunan sakamako na shan Metformin
Nazarin aikin likita da sake dubawa na marasa lafiya sun nuna cewa wannan hypoglycemic yana da mummunan tasiri. Wannan shi ne saboda wannan ƙara yawan aiki a cikin hadawan abu da iskar shaka na lipids. Yayin wannan tsari na biochemical, mai yawa ba wai kawai ana samar da makamashi ba, har ma da lactate (lactic acid), wanda yawanci yakan haifar da acidosis, wato, juyawa a cikin jigidar hydrogen zuwa ga acid ɗin. Wannan yana nufin akwai acid a cikin jini fiye da yadda ake buƙata, wanda ke rikitar da aikin dukkan gabobin da tsarin har mutuwa.
Lactic acidosis na iya faruwa duka a hankali kuma ba tsammani. Yawancin lokaci alamunta suna da sauƙi kuma marasa mahimmanci, amma wani lokacin yana zuwa rikice-rikice yayin da ake buƙatar dialysis (wato haɗa haɗin ƙwayar wucin gadi zuwa na'urar). Bayyanar cututtukan lactic acidosis sune kamar haka:
- bayyanar rauni;
- nutsuwa
- Dizziness
- m numfashi;
- karancin numfashi
- karancin jini;
- karancin zafin jiki;
- ciwon tsoka, da sauransu.
Kulawa da lactic acidosis yawanci alama ce, a lokuta mafi ƙaranci, an tsara hemodialysis (ƙwararrun hanya don tsarkake jini).
Me ake amfani da Metformin?
Amfani da miyagun ƙwayoyi an yi shi ne don magance cututtukan type 2, da kuma rigakafin wannan cuta. Likitoci sau da yawa suna ba da magani don magance nauyi mai yawa, tsufa mai saurin haɓaka, don daidaita tsarin metabolism.
Contraindications don amfani da Metformin
Bai kamata a yi amfani da wakili don lura da ciwon sukari a cikin waɗannan lambobin masu zuwa ba:
- yayin daukar ciki da lactation;
- yara ‘yan kasa da shekara 10;
- karancin kalori;
- bayan aiki da raunin da ya faru;
- tare da cututtukan hanta;
- tare da lactic acidosis na baya;
- idan akwai hali zuwa lactic acidosis;
- a gaban kasala gazawar a cikin anamnesis.
Yadda ake ɗaukar metformin?
Yana da mahimmanci ga marasa lafiya waɗanda ke son warkewar wucewar glucose a cikin jini su san yadda ake shan metformin tare da ciwon sukari. Ya kamata a lura cewa kasuwa tana ba da kudade tare da allurai dabam-dabam, daga 500 MG zuwa 1000 MG. Hakanan akwai magunguna waɗanda ke da sakamako mai tsawo. An wajabta kashi na farko a cikin ƙaramin sashi, bayan wannan likita na iya ba da shawarar karuwa a ciki. Hakanan yawan lokuta a rana kuma likita zasu iya daidaita shi, amma matsakaicin izinin adadin yau da kullun bai wuce 2 g ba.
Abin da za a yi tare da yawan shan magani
Karka kara yawan maganin don inganta tasirin magani ko kuma ka hanzarta lokacin warkarwa. Yawancin lokaci, yawan abin sama da ya kamata ya ƙare a cikin disrepair - yana haifar da mummunar cutar ga jiki, lokuta masu mutuwa ba sabon abu bane.
Hadarin da ke tattare da wuce haddi na Metformin shine haɓakar lactic acidosis. Alamar halayyar cutar ita ce abar ciki (wato, a cikin ciki) da kuma raunin ƙwayar tsoka, matsalolin narkewa, hanzarta numfashi, ƙarancin zafin jiki, ƙuna da rashin asara har zuwa kwaro.
Idan kuna da akalla ɗayan waɗannan alamun, yakamata ku daina shan magani kuma nan da nan ku nemi likita. Asibitin zai dauki dukkan matakan domin cire lactate daga jiki. A cikin mafi yawan lokuta masu rauni, an wajabta maganin hemodialysis. Yana da tasiri sosai kuma yana ba da sakamako mai sauri.
Yin hulɗa tare da wasu magunguna
Wannan asalin biguanide yana da sifofi na halayyar - kusan dukkanin abubuwan suna fitowa ta hanyar kodan ba su canzawa ba, sauran kashi (kimanin kashi 10%) suna tara a jikin mutum. Kuma idan kodan suka fara aiki ba da jimawa ba, Metformin yana tara abubuwa har cikin kyallen, wanda hakan yakan haifar da mummunan sakamako har zuwa rashin lafiya.
Hakanan yana da mahimmanci a daidaita daidaituwa game da amfani da wakilai na hypoglycemic tare da insulin. Bayan haka, idan Metformin ya bayyana kasancewa cikin jini sama da yadda ake tsammani, mai haƙuri tare da gabatarwar insulin zai iya fada cikin ƙwayar cutar hypoglycemic saboda raguwa sosai a cikin matakan glucose.
Hakanan ana samun raguwar hauhawar jini a cikin jini tare da yin amfani da waɗannan magunguna masu zuwa tare da Metformin:
- Abubuwan da suka samo asali na sulfonylurea;
- NSAIDs;
- Hankalin ƙwayoyin cuta;
- Masu hana MAO (tsaffin magungunan gargajiya);
- acarbose;
- ACE masu hanawa;
- cyclophosphamide;
- ckers-masu hanawa
Kuma waɗannan kuɗaɗen, yayin amfani da magani na rage sukari, akasin haka, rage ayyukanta:
- corticosteroids;
- kwayoyin hodar iblis;
- kamuwa da cuta;
- estrogens;
- maganin hana haihuwa;
- nicotinic acid;
- alli mai ɗauke da baƙin ƙarfe;
- adrenomimetics;
- isoniazids, da sauransu.
Don haka, Metformin ingantaccen magani ne mai rage sukari wanda ke da babban aiki, amma a lokaci guda ba magani bane na duniya. Yana da mummunan tasirin sa da kuma contraindications. Yawancin su ƙanana ne kuma suna wucewa a cikin makonni 1-2, amma wasu na iya tilasta dakatar da shan.
Domin magungunan suyi tasiri, ya zama dole don daidaita sashi tare da likita, bi duk shawarwarinsa, yin biyayya ga abincin da aka tsara kuma a hankali kula da contraindications da illarsa. Hakanan kuna buƙatar tuna cewa barasa shine babban abokin gaba na Metformin, saboda haka ya kamata a cire abubuwan sha da ke kunshe da giya yayin jiyya. Wannan shi ne saboda gaskiyar cewa barasa yana hana aikin enzymes na hanta da dama. Don haka, ƙarin Metformin yana shiga cikin jini, wanda ke haifar da raguwa mai yawa a cikin matakan glucose har zuwa hypoglycemia. Bugu da kari, barasa lokacin hulɗa tare da miyagun ƙwayoyi yana samar da lactic acid. Saboda haka, yin amfani da shi lokacin magani tare da wannan magani yana contraindicated.
