Binciken marasa lafiya da suka yi amfani da Glimecomb a cikin nau'in na biyu na maganin cututtukan mellitus na cutar yana nuna babban tasirin maganin. Wannan magani yana baka damar sarrafa matakan sugars a jikin mai rashin lafiya.
Glimecomb samfurin magani ne, ana samunsu ta fuskokin fararen kofuna masu farin ciki tare da tirin mai kirim. Kowane kwamfutar hannu an raba shi cikin rabi ta hanyar haɗari a farfajiya kuma yana da fuka-fukai. A cikin kera samfurin magani, ana yarda da kasancewar marbling a saman allunan.
Abun da ke cikin miyagun ƙwayoyi ya haɗa da metformin a cikin hanyar hydrochloride azaman aiki mai ƙarfi dangane da tsarkakakken abu a cikin girman 500 MG da glycoslide dangane da tsarkakakken abu a cikin girman 40 MG.
Abubuwan taimako na miyagun ƙwayoyi sune sorbitol, povidone, croscarmellose sodium da magnesium stearate.
Ana amfani da kayan aikin don maganin baka a matsayin magani na hypoglycemic. Ana haɗuwa da wannan magani, tunda yana haɗa da ƙwayoyin mahaɗan da ke da alaƙa da biguanides da sulfonylureas.
Pharmacokinetics na samfurin magani
Ana amfani da miyagun ƙwayoyi ta kasancewar kasancewar cututtukan cututtukan cututtukan cututtukan fata da cututtukan cututtukan fata.
Gliclazide yana ƙarfafa samuwar insulin ta hanyar ƙwayoyin beta na pancreas kuma yana ƙaruwa ji daɗin ƙwayoyin insulin-dogara da ƙwayoyin sel zuwa insulin na hormone. Bugu da ƙari, fili yana taimakawa haɓaka ƙwayar enzyme - ƙwayar glycogen synthetase. Yin amfani da gliclazide yana taimakawa wajen dawo da farkon farkon kwayar insulin kuma yana rage hypglycemia na postpradial.
Bugu da ƙari ga tasirin ayyukan tafiyar carbohydrate metabolism, yin amfani da wannan fili yana shafar microcirculation na jini, yana rage matakin adhesion da haɗuwar platelet, yana rage jinkirin ci gaban ƙwaƙwalwar ƙwayar cuta na fitsari, ya dawo da martabar ganuwar tsokoki na jijiyoyin jiki, rage martanin bangon jijiyoyin bugun jini zuwa adrenaline idan akwai microangiopathy.
Amfani da gliclazide yana taimakawa rage jinkirin ciwan cututtukan ƙwayar cuta, kuma a gaban nephropathy, ana lura da raguwar proteinuria.
Metformin shine mahaɗan sunadarai mallakar ƙungiyar biguanide. Wannan fili yana taimakawa rage abun cikin sukari a cikin jini. Ana samun tasirin ne ta hanyar hana aiwatar da gluconeogenesis a cikin kwayoyin hanta, haka kuma ta hanyar rage girman yadda sinadarin glucose din ke gudana a cikin jijiyoyin mahaifa, haka kuma ta hanyar inganta shakar glucose ta kwayoyin jikin jikin. Amfani da metformin yana taimakawa rage ƙwayar ƙwayar cuta, ƙwayar cholesterol da ƙarancin lipoproteins mai yawa. Gabatar da metformin a cikin jiki yana samar da raguwa da kwantar da nauyin jiki.
Yin amfani da metformin a cikin rashin insulin a cikin jini ba ya haifar da bayyanar da sakamako na warkewa kuma abin da ya faru na hypoglycemic halayen ba a lura. Yin amfani da metformin yana haɓaka ƙirar fibrinolytic na jini.
Ana samun wannan ta hanyar dakatar da nau'in mai hana nau'in motsa nama.
Manuniya da contraindications don amfani da miyagun ƙwayoyi
Abubuwan da ke nuna alamun amfani da Glimecomb sune nau'in ciwon sukari na 2 a cikin rashin ingancin amfanin yin amfani da maganin warkewar abinci da motsa jiki, kazalika da rashin sakamakon tasirin warkewa da aka gudanar tare da taimakon metaformine da glycazide.
Ana amfani da Glimecomb don maye gurbin maganin da aka gudanar a baya tare da magunguna biyu na Metformin da Glycoside, idan har matakan sukari na jini sun tabbata kuma suna da kyau.
Glimecomb yana da cikakkun hanyoyin contraindications don yin amfani da miyagun ƙwayoyi.
Babban daga cikin contraindications sune kamar haka:
- Rashin hankali na jikin mai haƙuri zuwa sakamakon metformin, gliclazide ko wasu sulfonylureas. Bugu da kari, bai kamata a yi amfani da miyagun ƙwayoyi a gaban bayyanarwar rashin lafiya ga ƙarin abubuwan haɗin magungunan ba.
- Kasancewar nau'in ciwon sukari na 1.
- Kasancewar cutar ketoacidosis na masu ciwon sukari, yawan ciwon sukari da kuma abubuwan da suka faru na cutar mahaifa.
- A ci gaba da mai girma na koda rashin ƙarfi.
- Haɓaka mummunan yanayin da zai iya haifar da canji a cikin aikin kodan, haɓaka rashin ruwa a jiki, kamuwa da cuta da rawar jiki.
- Samuwar cututtukan cututtukan cututtukan fata da kuma m, tare da abin da ya faru na hypoxia.
- Aukuwa na renal gazawar.
- Ciwon ciki.
- Lokacin haihuwar da lokacin shayarwa.
- Gudanar da miconazole lokaci guda.
- Cututtukan da ke tattare da cutarwa da hanyoyin tiyata, ƙonewa da yawa da manyan raunin da ya faru, waɗanda yayin aikin jiyya suna buƙatar yin amfani da maganin insulin.
- Kasancewar rashin shan giya da matsanancin maye.
- Ci gaban lactic acidosis.
- Biye da karancin abincin carb.
Baya ga waɗannan lamuran, an hana miyagun ƙwayoyi yin amfani da shi lokacin da ake amfani da shi don bincika sinadarin iodine-mai ɗauke da abubuwan kwatankwacin fili.
Kada kuyi amfani da magani don maganin ciwon sukari a cikin marasa lafiya waɗanda suka kai shekaru 60, suna fuskantar wahala ta jiki. Wannan ya faru ne saboda tsananin yiwuwar haɓakar lactic acidosis a cikin irin waɗannan marasa lafiya.
Ya kamata a kula da kulawa ta musamman yayin ɗaukar miyagun ƙwayoyi idan mai haƙuri yana da alamar febrile, ƙarancin aiki a cikin glandon adrenal, kasancewar hauhawar jijiyoyin tsoka, cututtukan thyroid, wanda ke haifar da ƙetarewar aikinta.
Amfani da magani
Umarnin don amfani da Glimecomba yana tsarawa da kuma bayyana dalla-dalla ga kowane yanayi inda aka bada shawarar shan miyagun ƙwayoyi da lokacin da aka haramta amfani da miyagun ƙwayoyi. Jagororin suna ba da cikakken bayani game da tasirin sakamako wanda zai faru lokacin amfani da samfurin da shawarar shawarar don amfani.
Ana amfani da maganin a baki lokacin abinci ko kuma bayansa. Matsayin da ake buƙata don ƙaddamarwa shine ƙwararren likita mai halartar ya dace da sakamakon binciken da kuma halayen mutum na jikin mai haƙuri. An ƙaddara yawan maganin yana daidai da matakin glucose a jikin mai haƙuri.
Mafi sau da yawa, kashi na farko na maganin da likitan ya ba da shawarar ga mai haƙuri shine allunan 1-3 a kowace rana tare da zaɓin hankali na kashi don tabbatar da sakamako mai ƙarfi don ciwon sukari mellitus. Idan ba ku bi shawarwarin ba, to cutar zazzabin cizon sauro zata haɓaka.
Mafi sau da yawa, ya kamata a sha miyagun ƙwayoyi sau biyu a rana da safe da maraice. Kuma matsakaicin adadin maganin zai iya zama allunan 5.
Akwai wasu umarnai na musamman waɗanda dole ne a bi su lokacin aiwatar da aikin Glimecomb:
- ya kamata a gudanar da magani kawai a hade tare da abinci mai kalori mai ɗauke da ƙananan adadin carbohydrates;
- Ya kamata marasa lafiya su sami abinci mai kyau na yau da kullun, wanda ya haɗa da karin kumallo;
- Domin guje wa ci gaban bayyanar cututtuka na cututtukan cututtukan jini, ya kamata a zaɓi zaɓi guda ɗaya na mutum;
- lokacin da aka matsa lamba ta jiki da tausayawa a jiki, ana buƙatar daidaita sashi na maganin da za a sha;
Lokacin gudanar da aikin jiyya tare da magani irin su Glimecomb, ya kamata ka ƙi shan giya da abinci wanda ke ɗauke da ethanol.
Dole ne a yi taka tsantsan musamman a yayin amfani da miyagun ƙwayoyi yayin shiga cikin waɗancan nau'ikan aikin waɗanda ke buƙatar karuwar hankali da saurin halayen.
M sakamako masu illa
Lokacin shan magani, mai haƙuri na iya fuskantar yawan adadin sakamako masu illa.
A cikin tafiyar matakai na rayuwa, sabawa sashi ko yayin amfani da abincin da bai dace ba, rikice-rikice na iya haɓaka wanda ke haifar da hauhawar jini. Wannan halin na jiki yana tattare da ciwon kai, bayyanar da jin gajiya, da karfin ji, yunwar, karuwa a cikin zuciya, bayyanar tsananin farin ciki, da nakasa daidaituwa da motsawa.
Bugu da ƙari, idan akwai lamuran ƙetarori a cikin haƙuri, yanayin lactic acidosis na iya haɓaka, wanda aka nuna ta hanyar rauni myalgia, ƙara yawan nutsuwa, jin zafi a ciki da raguwar hauhawar jini.
Wadannan rikice-rikice masu zuwa na iya faruwa a cikin tsarin narkewa:
- bayyanar ji na tashin zuciya;
- ci gaban zawo;
- bayyanar ji na nauyi a cikin epigastrium;
- bayyanar da dandano na karfe a bakin;
- rage cin abinci;
- a cikin lokuta mafi ƙaranci, lalacewar hanta kamar hepatitis, cholestatic jaundice da wasu mutane ke haɓaka.
Idan akwai mahaukaci a cikin hanta, yakamata a dakatar da maganin nan da nan.
A take hakkin sashi da ka'idodi na far, ci gaban hanawa na hematopoietic aiki mai yiwuwa ne.
A matsayin sakamako masu illa, mai haƙuri na iya haɓaka rashin lafiyan, wanda aka nuna a cikin yanayin itching, urticaria da maculopapular fatar.
Idan mai haƙuri yana haɓaka sakamako masu illa daga shan miyagun ƙwayoyi, ya kamata ku hanzarta rage sashi ko dakatar da amfani da magani.
Tsarin saki, yanayin ajiya da sharuɗɗa, analogues da farashi
Ana samun magungunan a cikin nau'ikan allunan a cikin kwalaben filastik. Kwalba ɗaya ta ƙunshi, gwargwadon ɗakunan, 30,60 ko Allunan 120. Bugu da kari, ana samun magungunan a cikin nau'ikan allunan da aka rufe cikin kunshin firinji. Tare da wannan nau'in sakin, kowane kunshin ya ƙunshi Allunan 10 ko 20.
Kowane kwalban an cushe a cikin kwali na kwali, a ciki an sanya umarnin don amfani da miyagun ƙwayoyi. Har ila yau ana tattara abubuwan sutturar salula a cikin fakiti. Dogaro da Allunan da suke a cikin kunshin salula, adadin ƙarshe a cikin fakiti ya bambanta. Jimlar allunan alluna 60 ko 100.
Magungunan yana cikin jerin B. Samfurin ya kamata a adana shi a cikin wuri mai bushe da duhu a zazzabi da bai wuce 25 digiri Celsius ba.
Umarnin Glimecomb yana buƙatar ajiya a cikin wurin da ba a iya kaiwa ga yara. Rayuwar shiryayye na miyagun ƙwayoyi shine shekaru 2.
Ana bayar da maganin a kantin magani sosai gwargwadon abin da aka tsara.
Kamfanin da ya kirkira shi a yankin Tarayyar Rasha shine JSC Chemical and Pharmaceutical Combine AKRIKHIN.
Analogues na gida na miyagun ƙwayoyi sune Glidiab, Glidiab MV, Gliclazide MV, Gliformin, Gliformin Prolong da Diabefarm da wasu.
Farashin Glimecomb a cikin kantin magunguna daban-daban sun tashi daga 232 zuwa 600 rubles, ya danganta da yankin Tarayyar Rasha da mai ba da kaya. Farashin analogues na miyagun ƙwayoyi da aka samar a cikin Tarayyar Rasha, dangane da yankin, ya tashi daga 158 zuwa 300 rubles. A cewar marasa lafiya, analolera na miyagun ƙwayoyi ba su da ƙanƙanta da shi a cikin tasirin haɗuwa ga mai haƙuri da ciwon sukari. Bidiyo a cikin wannan labarin zai mayar da hankali kan lura da ciwon sukari.
