Lovastatin (kwamfutar hannu ta lovastatin) magani ce ta farko-ta rage rage kiba. Halinsa na musamman shine ikon ingantaccen tasiri ga ƙananan ƙananan ƙwayoyin cholesterol da dalilai na haɓaka matakin abu.
Likitocin sunyi la'akari da miyagun ƙwayoyi ɗayan ɓoyayyen mutummutumai, abubuwan da ke aiki sune na halitta ga jikin mutum. A cikin kananan allurai, suna nan a wasu abinci, alal misali, a cikin namomin kaza na namomin kaza.
Maganin yana cikin nau'i na allunan wanda aka lullube shi da murfin kariya. Launi ya bambanta daga fari zuwa launin rawaya, yana haɗa da alli lovastatin, sitaci masara, silicon dioxide, lactose monohydrate, magnesium stearate. A cikin kantin magunguna, ana iya siyan allunan Lovastatin cikin magunguna daban-daban: 20, 20 ko 40 mg.
Aikin magunguna
Bayan shiga cikin narkewar narkewar mutum, allunan suna iya yin illa ga enzymes, sannu a hankali suka rushe kuma suka karye ta ganuwar gabobin ciki. Yawan sha kai tsaye ya danganta da yadda ake amfani da miyagun ƙwayoyi, gwargwadon hakan, da sauri abubuwan da ke motsa jiki su shiga cikin jini.
A cikin jini, samfurin yana haɓaka ƙawance mai ƙarfi tare da sunadarai, wanda ke ba da gudummawa ga saurin shigar cikin jijiyoyin jiki, tasirin warkewa. Jiyya yana faruwa a cikin kwatance guda biyu lokaci guda, wanda ke sa magani ya zama mafi shahara tsakanin statins.
Da farko, Lovastatin ya lalata aikin samarda cholesterol, baya bada izinin ragewa ya canza zuwa mevalonate. A mataki na gaba, ana kara haɓakar catabolism na abubuwa masu ƙarancin ƙarfi, triglycerides, da kuma ƙwayar cholesterol masu yawa.
Saboda haka, miyagun ƙwayoyi suna da tasirin warkewa nan take kuma ya zama ma'auni na rigakafin ci gaban cholesterol mai zuwa. Sakamakon hanzari metabolism:
- tarawa ba fiye da kashi ɗaya ba;
- rabin rayuwa awowi uku ne;
- tasirin yana ɗaukar tsawon sa'o'i 14.
Cire kayan aiki yana faruwa ne ta hanjin hanji, sauran kuwa ta hanjin kodan tare da fitsari.
An bayyana tasirin warkewar cutar bayan makonni biyu da amfani da magani na yau da kullun, sinadarin ya kai matsayin mafi kololuwa bayan wata daya da rabi na jiyya.
Tare da amfani da tsawan lokaci, tasiri na Lovastatin baya raguwa.
Umarnin don amfani da miyagun ƙwayoyi
Ana bada shawarar Lovastatin na miyagun ƙwayoyi don lura da nau'in hypercholesterolemia na farko. Hakanan ana amfani dashi azaman hanyar kawai a haɗe tare da hanyoyin kwantar da hankali marasa amfani (motsa jiki, abinci).
Allunan an wajabta su don magance cututtukan hyperlipoproteinemia, haɓakar hypercholesterolemia, atherosclerosis na tasoshin jini. Tare da miyagun ƙwayoyi, yin amfani da mayuka mai ɗacin rai, ana nuna hanya da bitamin da ma'adanai.
Ana ba da shawarar rage cin abinci da daidaitaccen aiki na jiki tare da magani. Amfani da maganin yana ba da ɗan haɗari na canji na nau'in 1 da nau'in ciwon sukari na 2 a cikin siffofin mafi rikitarwa.
Ana iya haɓaka Lovastatin tare da amfani da magunguna masu rage sukari, an nuna shi don rigakafin cututtuka na tsarin zuciya. Yin amfani da miyagun ƙwayoyi tare da yiwuwar dawowa baratacce ne:
- bugun jini;
- karancin lalacewa;
- thrombosis.
An ɗauke shi ta hanyar masu ciwon sukari tare da haɗarin farfadowa na jijiyoyin zuciya, cututtukan angina pectoris, rashin lafiya na jijiya.
Sun fara shan kwayoyin lokacin da hanyoyin da ba magunguna ba ba su ba da sakamakon da aka yi niyya. Ba kamar yawancin gumakan da ake amfani da su sau ɗaya a rana ba, ana iya amfani da lovastatin a ma'auni iri ɗaya tare da tazara na awanni 12.
Kashi na farko na miyagun ƙwayoyi bai kamata ya wuce 10 MG ba, a nan gaba (dangane da ilimin halayyar cuta da rikitarwa), adadin ƙwayar yana karuwa a kowane makonni 2-4. Ana iya ɗaukar nauyin 80 MG a cikin rana.
Decreasearin raguwa a cikin aikin mai-kamar abubuwa masu ƙima da ƙima yana buƙatar raguwa a cikin yawan ƙwayoyi. Kowane mako, ana rage adadin maganin a cikin 10 MG. Hakanan, za a iya rage sashi da rabi, amma wannan zai iya zama kawai idan:
- yawan amfani da giya;
- wucewa ta hanyar immunosuppressants;
- na kullum hanya na hanta cututtuka na kowane etiology.
Ana aiwatar da raguwar sashi ne yayin jiyya tare da wakilai na antifungal, maganin rigakafi, da magunguna waɗanda ke dauke da maganin rashin ƙarfi.
Ba za ku iya haɗa Lovastatin tare da cyclosporins ba, saboda a wannan yanayin zai zama da wuya a bi sawun abubuwan da ke aiki a cikin jinin mai haƙuri.
Contraindications, m halayen, overdose
Tare da ciwon sukari, ƙwayar da keɓaɓɓiyar cholesterol bai dace da duk marasa lafiya ba. Don haka, contraindications ya haɗa da rashin haƙuri na mutum zuwa ga abubuwan aiki masu aiki ko mai taimako na miyagun ƙwayoyi, babban aikin transaminases a cikin hanta, da gazawar hanta.
Likitocin ba sa yin amfani da Lovastatin a lokacin daukar ciki na kowane zamani da kuma lokacin shayarwa, ga yara 'yan ƙasa da shekaru 18. Ba a tabbatar da amincin amfani da allunan ga marasa lafiya na wannan rukunin ba, ba a yi nazarin tasirin magani ba.
Sau da yawa, miyagun ƙwayoyi kuma yana ba da halayen m. Ofayansu shine cutar maimaitawa. Idan akwai raɗaɗin ciwo da rauni a cikin tsokoki na baya, ya kamata ka nemi likita don shawara. Bayan tabbatar da cutar myopathy, an dakatar da hanya, ana ba da maganin analogues.
Tsarin haifuwa baya ware raguwa a cikin libido, lalatawar mahaifa, gynecomastia. A wani sashin gabobin hangen nesa, jan ido na idanu, hangen nesa, da ruwan tabarau mai haske.
Sauran sakamakon da ba a ke so na magani, canje-canje ne na cututtukan hanta. A saboda wannan dalili, tare da tsinkayar cutar cututtukan kwayoyin, ana buƙatar nazarin ƙwayar halittar hanta a kowane watanni uku.
Tare da karuwa a cikin ayyukan transaminases zuwa matakan mahimmanci, wajibi ne a daina ɗaukar allunan. Hakanan, janyewar maganin yana buƙatar kowane sakamako masu illa:
- tashin zuciya
- amai
- zawo
- fata fatar jiki;
- itching
A cewar likitoci, Lovastatin magani ne mai inganci kuma mai lafiya wanda ya dace sosai don jiyya da rigakafin atherosclerosis na hanyoyin jini. Sau da yawa, koda tare da amfani na tsawan lokaci, yana da kyau ta yarda da shi, yana da wuya a ruwaito shi a cikin cigaban illolin da ba a so.
Koyaya, a cikin 2012, binciken da aka gudanar wanda ya nuna wasu sakamako masu illa. Daga cikin su akwai asarar ƙwaƙwalwar ajiya, mantawa da ɓangare, damuwa da juyawar yanayi.
Idan mai ciwon sukari ya dauki ƙarin ƙwayoyi na ƙwayar cuta, an wajabta masa magani na alama. Ya zama dole a sha ruwa mai tsabta yadda zai yiwu, don ɗaukar enterosorbents da absorbents a baki. Hakanan an nuna gabatarwar diuretics. Cututtukan zuciya ba ya ba da wani takamaiman sakamako, amma akwai barata a cikin mawuyacin yanayi na yawan yawan shan ruwa.
Bayan an wuce gona da iri, hanya ta biyu ta farawa ba ta wuce ba bayan watanni 6 kuma koyaushe ƙarƙashin kulawar likita.
Lovastatin analogues
| Take | Farashi a cikin rubles |
| Medostatin | 550 |
| Mevacor | 220 |
| Cardiostatin | 240 |
| Rovacor | 390 |
| Holartar | 190 |
| Lovacor | 280 |
| Lovasterol | 200 |
Yaushe, saboda wasu dalilai, Lovastatin bai dace da masu ciwon sukari ba, bai samo maganin ba a cikin kantin magani mafi kusa, kuna buƙatar ɗaukar ma'anar magungunan. Irin waɗannan magunguna daidai suke a cikin kayan aiki, na iya maye gurbin maganin na asali.
Don Lovastatin, farashin ya tashi daga 180 zuwa 300 rubles. A cikin wasu halaye, magunguna sun fi sauki fiye da analogues. Kuna iya siyan sa a cikin cibiyar sadarwar magunguna ba tare da takardar izini daga likita ba.
Nazarin game da kwayoyin a cikin mafi yawan suna da inganci.
Hulɗa da ƙwayoyi
Yin amfani da magani a lokaci ɗaya tare da wakilai na antifungal yana tsokani ci gaban myopathy, lalata ƙwayar tsoka. Har ila yau, haɗarin cutar ta mahaifa yana da alaƙa da amfani da adadin ruwan 'ya'yan innabi a lokaci guda.
Idan mai ciwon sukari ya dauki Lovastatin tare da Warfarin, yana cikin barazanar zubar jini. Lokacin yin magani tare da Colestiramin, bioavailability na miyagun ƙwayoyi yana raguwa, saboda wannan dalili yana da mahimmanci don kula da tazara tsakanin sa'o'i 2-4 tsakanin magungunan.
Lokacin da aka haɗu da maganin tare da maganin anticoagulants, abubuwan da aka samo daga coumarin, zubar jini yana ƙaruwa kuma lokacin prothrombin yana ƙaruwa. Magani ya san lokuta idan mai ciwon sukari ya kamu da matsanancin rashin lafiya.
Magungunan yana rage haɗarin cututtukan cututtukan zuciya. Idan an riga an gano waɗancan, maganin zai taimaka:
- ƙarfafa ganuwar bugun jini;
- ƙananan ƙwayoyin cuta mai ƙananan ƙarfi;
- inganta kyautatawa mai haƙuri.
Game da gazawar koda, ana ɗaukar allunan a gwargwadon ƙarfin 20 na MG. Lokacin amfani dashi tare da kwayoyi don lalata rigakafi, babu abin da ya wuce 20 MG na abu a rana kuma.
Yayin aikin, mai ciwon sukari dole ya bi abinci tare da rage kwalagin kwala. An bada shawara daga lokaci zuwa lokaci don bincika taro na abu mai kama da jini, gudanar da gwajin hanta. Hakan yana da muhimmanci a lura da yanayin majinyacin. Alamar game da buƙatar soke ma'ana zai zama zaƙi da zafin tsoka.
Masana za su yi magana game da mutummutumai a cikin bidiyo a cikin wannan labarin.
