Siofor don asarar nauyi, lura da ciwon sukari na 2 da rigakafin ta

Siofor shine mafi mashahuri magani a cikin duniya don yin rigakafi da magani na ciwon sukari na 2. Siofor shine sunan kasuwanci don magani wanda sinadarin aikinsa metformin yake aiki. Wannan magani yana ƙara ji daɗin ƙwayoyin sel zuwa aikin insulin, i.e., yana rage juriya na insulin.

Wannan magani yana inganta cholesterol da triglycerides a cikin jini, yana rage haɗarin cutar zuciya, kuma mafi mahimmanci - yana taimakawa rage nauyi.

Miliyoyin marasa lafiya da ke fama da ciwon sukari na 2 a duniya ke ɗaukar Siofor. Wannan yana taimaka musu su kula da lafiyar jini mai kyau, ban da bin abinci. Idan aka fara magance cututtukan type 2 na kan lokaci, Siofor (Glucophage) na iya taimakawa ba tare da allurar insulin ba da kuma shan wasu kwayoyin da ke rage sukarin jini.

Umarnin don maganin Siofor (metformin)

Wannan labarin ya ƙunshi '' cakuda '' umarnin hukuma don Siofor, bayani daga mujallolin likita da sake dubawa game da marasa lafiya da ke shan maganin. Idan kuna neman umarnin Siofor, zaku sami duk mahimman bayanan da ke tare da mu. Muna fatan cewa mun sami damar gabatar da bayani game da waɗannan allunan sanannu sanannu a cikin hanyar da ta fi dacewa a gare ku.

Siofor, Glucofage da kwatankwacinsu

Glucophage magani ne na asali. Wani kamfani ne ya ƙirƙira metformin a matsayin magani don maganin ciwon sukari na 2. Siofor sigar analog ce ta kamfanin kasar Jamus Menarini-Berlin Chemie. Waɗannan su ne mafi mashahuri allunan metformin a cikin ƙasashen masu magana da Rashanci da Turai. Suna da arha kuma suna da kyakkyawan aiki. Glucophage - magani ne mai dadewa. Yana haifar da rikicewar narkewa sau biyu kasa da metformin na yau da kullun. Glucophage shima ana jin zai iya rage sukari mafi kyau a cikin masu ciwon suga. Amma wannan magani ya fi tsada sosai. Duk sauran zabin kwamfutar hannu metformin da aka lissafa a saman tebur ba su da amfani. Babu isasshen bayanai kan ingancinsu.

Alamu don amfani

Nau'in ciwon siga na 2 na ciwon sukari (wanda ba shi da insulin) ba, don magani da rigakafin. Musamman a hade tare da kiba, idan ilimin abinci da ilimin ilimin jiki ba tare da kwayoyin magani ba su da tasiri.

Don lura da ciwon sukari, za'a iya amfani da Siofor azaman monotherapy (magani ɗaya kawai), kamar yadda kuma a hade tare da wasu allunan da ke rage sukari ko insulin.

Contraindications

Contraindications wa alƙawarin siofor:

• iri na 1 ciwon sukari mellitus (*** ban da lokuta masu kiba.Idan kana da nau'in ciwon sukari guda 1 da ƙari masu yawa - shan Siofor na iya zama da amfani, ka shawarci likitan ka);
• cikakken katsewar insulinwar kansa ta hanji a cikin nau'in ciwon sukari guda 2;
• mai cutar kansa, mai fama da cutar kansa;
• gazawar renal tare da matakan halittar jini sama da 136 μmol / l a cikin maza kuma sama da 110 μmol / l a cikin mata ko darajar filtering glomerular (GFR) ƙasa da 60 ml / min;
• aikin lalata hanta
• kasawar zuciya, rashin iya aiki;
• gazawar numfashi;
• anemia
• yanayin m wanda zai iya taimakawa aikin keɓaɓɓen aiki (rashin ruwa, ƙwararrun cututtuka, rawar jiki, gabatarwar abubuwa na aidin);
• Nazarin X-ray tare da bambancin aidin - wanda ke buƙatar sokewa na wucin gadi na siophore;
• aiki, raunin da ya faru;
• Yanayin catabolic (yanayi tare da ingantattun hanyoyin lalata, alal misali, idan akwai cututtukan tumo);
• na kullum mai shan giya;
• lactic acidosis (wanda ya haɗa da canjawa wuri);
• ciki da shayarwa (shayarwa) - kar a dauki Siofor yayin daukar ciki;
• rage cin abinci tare da rage iyakancewar yawan caloric (kasa da 1000 kcal / day);
• shekarun yara;
• rashin hankali ga abubuwan da ke cikin miyagun ƙwayoyi.

Umarnan yana ba da shawarar cewa allunan metformin an tsara su tare da taka tsantsan ga mutanen da shekarunsu suka wuce 60 idan suna cikin aiki na zahiri. Domin wannan rukuni na marasa lafiya yana da haɓakar haɗarin lactic acidosis. A aikace, da alama wannan rikicewar a cikin mutane tare da hanta mai lafiya yana kusa da sifili.

Siofor don asarar nauyi

A yanar gizo, zaku iya samun rayayyun ra'ayoyi masu kyau daga mutanen da suke ɗaukar Siofor don asarar nauyi. Umarni na hukuma game da wannan magani bai ambaci cewa za a iya amfani da maganin ba kawai don rigakafin ko lura da ciwon sukari ba, kawai don rasa nauyi.

Koyaya, waɗannan kwayoyin suna rage ci abinci da haɓaka metabolism wanda yasa yawancin mutane ke gudanar da "asarar" poundsan fam. Tasirin Siofor don asarar nauyi ya ci gaba har sai mutum ya ɗauke shi, amma sai kitse ya ajiye da sauri.

Tabbas, Siofor don asarar nauyi shine ɗayan mafi aminci a cikin dukkanin kwayoyin don asarar nauyi. Abubuwan sakamako masu illa (banda bloating, zawo da ƙarancin ƙwayar cuta) suna da wuya sosai. Bugu da kari, shima magani ne mai araha.

Siofor don asarar nauyi - kwaya mai tasiri don asarar nauyi, mai aminci

Idan kana son yin amfani da Siofor don asarar nauyi, da farko saika karanta sashen “Contraindications” da farko. Hakanan zai zama daidai don tuntuɓar likita. Idan ba tare da endocrinologist ba, to tare da likitan ilimin mahaifa - suna ba da wannan magani sau da yawa don cututtukan cututtukan ƙwayoyin cuta na polycystic. Testsauki gwajin jini da fitsari don bincika aikin koda da yadda hanjin ku yake aiki.

Lokacin da kuke shan kwayoyin don rage nauyin jiki - a lokaci guda kuna buƙatar biye da tsarin abinci. A hukumance, a irin waɗannan halayen, ana bada shawarar “mai fama da yunwa” mai ƙarancin kalori. Amma shafin yanar gizon masu ciwon sukari -Med.Com don kyakkyawan sakamako yana ba da shawarar yin amfani da Siofor don asarar nauyi tare da rage cin abinci tare da ƙuntata carbohydrates a cikin abincin. Wannan na iya kasancewa abincin Duk, Atkins ne ko kuma abincin da yake da karancin carbohydrate na masu ciwon suga. Duk waɗannan abubuwan rage cin abinci suna da abinci mai gina jiki, masu lafiya da inganci don asarar nauyi.

Da fatan za a ƙetare shawarar da aka ba da shawarar don kada acidosisis ya inganta. Wannan baƙon rikitarwa ba ne, amma mai mutuwa. Idan kuka wuce shawarar da aka ba da shawarar, ba zaku yi nauyi da sauri ba, kuma zaku ji sakamako masu illa na jijiyoyin jini a cikakke. Ka tuna cewa shan Siofor yana ƙaruwa da yiwuwar samun juna biyu cikin shiryawa.

A cikin Intanet na harshen Rashanci, zaku iya samun sake dubawa da yawa na matan da suka dauki Siofor don asarar nauyi. Fim ɗin wannan magani ya sha bamban sosai - daga mai daɗi zuwa mummunan aiki mara kyau.

Kowane mutum yana da nasa metabolism, ba daidai yake da kowa ba. Wannan yana nufin cewa amsawar jiki ga Siofor zai kasance daban-daban. Idan baku shirya shan kwaya a lokaci guda a matsayin mai karancin abinci mai narkewa ba, to kada kuyi tsammanin rasa nauyi kamar yadda marubucin bita a sama. Mai da hankali kan debe 2-4 kilogiram.

Wataƙila, Natalia ta bi tsarin rage kalori, wanda ba ya taimaka wajen rasa nauyi, amma a maimakon haka yana hana rage nauyi. Idan ta yi amfani da karancin carbohydrate, sakamakon zai bambanta sosai. Abincin furotin na Siofor + shine rage nauyi mai sauƙi kuma mai sauƙi, tare da yanayi mai kyau kuma ba tare da matsananciyar yunwar ba.

Wataƙila Valentina na haifar da ciwon haɗin gwiwa shine yanayin rayuwa, kuma ciwon sukari bashi da alaƙa da shi. An haifi mutum ne don motsawa. Yin aiki na jiki yana da mahimmanci a gare mu. Idan kun jagoranci salon tsinkaye, to bayan shekaru 40, cututtukan haɗin gwiwa, ciki har da amosanin gabbai da osteochondrosis, ba makawa suna faruwa. Hanya guda daya ta rage su ita ce koyon yadda ake motsa jiki tare da nishadi, kuma a fara yi. Ba tare da motsi ba, babu kwayayen da zasu taimaka, gami da glucosamine da chondroitin. Kuma Siofor bashi da abin zargi. Da aminci yana yin aikinsa, yana taimakawa rage nauyi da sarrafa ciwon sukari.

Wani wanda aka azabtar da karancin kalori, mai narkewa mai yawa wanda likitoci ke wajabta wa masu cutar siga. Amma Elena har yanzu ya sauka cikin sauƙi. Ita ma tana kula da rasa nauyi. Amma saboda tsarin abincin da ba daidai ba, da babu ma'anar komai daga shan Siofor, ko don rasa nauyi, ko don daidaita sukari na jini.

Natalya taka rawa sosai ƙara yawan kashi da kuma godiya ga wannan ta sami damar kauce wa sakamako masu illa. Ku ci abinci mai ƙayyadaddun carbohydrate - kuma nauyin ku ba zai narke ba, amma ya tashi ƙasa, ya rushe.

Siofor don rigakafin kamuwa da ciwon sukari na 2

Hanya mafi kyau don hana kamuwa da ciwon sukari na 2 shine canzawa zuwa yanayin rayuwa. Musamman, ƙara yawan aiki na jiki da canji a salon cin abinci. Abin takaici, mafi yawan marasa lafiya a rayuwar yau da kullun ba sa bin shawarwarin sauya rayuwar su.

Saboda haka, tambayar ta hanzari ta tashi dabarun dabarun rigakafin kamuwa da ciwon sukari na 2 ta amfani da magani. Tun daga 2007, ƙungiyar ƙwararrun cututtukan ta Americanasar Amurika ke ba da hukuma bisa hukuma game da amfani da Siofor don rigakafin cutar sankara.

Nazarin da ya shafe shekaru 3 ya nuna cewa yin amfani da Siofor ko Glucofage yana rage haɗarin kamuwa da ciwon sukari da kashi 31%. Don kwatantawa: idan kun canza zuwa rayuwa mai kyau, to wannan haɗarin zai ragu da kashi 58%.

Ana ba da shawarar yin amfani da allunan metformin don rigakafin a cikin marasa lafiya kawai da ke da haɗarin kamuwa da cutar sankara. Wannan rukunin ya haɗa da mutane underan shekaru 60 da kiba waɗanda ƙari kuma suna da ɗaya ko sama daga cikin abubuwan haɗari masu zuwa:

• glycated matakin haemoglobin - sama da 6%:
• hauhawar jini;
• ƙananan matakan “mai kyau” cholesterol (babban yawa) a cikin jini;
• dagagge jini triglycerides;
• akwai masu cutar sukari iri biyu a cikin dangi.
• bayanin jikin mutum ya fi ko daidai yake da 35.

A cikin irin waɗannan marasa lafiya, ana iya tattauna batun Siofor don rigakafin ciwon sukari a cikin sashi na 250-850 mg sau 2 a rana. A yau, Siofor ko nau'ikansa na Glucophage shine kawai magani wanda aka yi la'akari da shi azaman hanyar hana ciwon sukari.

Umarni na musamman

Kuna buƙatar saka idanu akan aikin hanta da koda kafin a rubuta allunann metformin sannan kuma kowane watanni 6. Yakamata a duba matakan lactate a cikin jini sau 2 a shekara ko fiye da haka.

A cikin lura da ciwon sukari, haɗuwa da siofor tare da abubuwan da ake amfani da su na sulfonylurea babbar haɗarin hypoglycemia. Sabili da haka, ana buƙatar saka idanu akan matakan glucose na jini sau da yawa a rana.

Sakamakon haɗarin hypoglycemia, marasa lafiya waɗanda ke shan siofor ko glucophage ba a ba da shawarar su shiga cikin ayyukan da ke buƙatar hankali da saurin psychomotor ba.

Side effects

10-25% na marasa lafiya da ke shan Siofor suna da gunaguni na sakamako masu illa daga tsarin narkewa, musamman a farkon farawa. Wannan dandano ne "ƙarfe" a cikin bakin, asarar ci, zawo, amai da gas, zafin ciki, tashin zuciya har ma da amai.

Don rage mita da kuma ƙarfin waɗannan tasirin sakamako, kuna buƙatar shan siofor yayin ko bayan abincin, kuma ku ƙara yawan ƙwayar a hankali. Abubuwan da ke tattare da jijiyoyi daga jijiyar ciki ba dalili bane na soke maganin Siofor. Saboda bayan lokaci kadan yawanci yakan tafi, koda da sashi guda ne.

Rashin ƙwayar cuta ta wucin gadi: abu ne mai ɗanɗano (tare da yawan shan ƙwayoyi, a gaban cututtukan haɗuwa, wanda ake amfani da Siofor, tare da barasa), lactate acidosis na iya haɓaka. Wannan yana buƙatar dakatar da magani nan da nan.

Daga tsarin haiatopoietic: a wasu halaye - megaloblastic anemia. Tare da jiyya mai tsawo tare da siophore, haɓakar B12 hypovitaminosis mai yiwuwa ne (ƙwaƙwalwar nakasa). Da wuya akwai halayen rashin lafiyan - fatar fata.

Daga tsarin endocrine: hypoglycemia (tare da yawan yawan maganin).

Pharmacokinetics

Bayan gudanarwar bakin, mafi girman haɗarin metformin (wannan shine sinadarin aiki na Siofor) a cikin jini na jini bayan an kusan awa 2.5. Idan kun sha kwayoyin hana daukar ciki da abinci, to shan shayarwa yayi saurin raguwa kuma yana raguwa. Matsakaicin metformin a cikin ƙwayar plasma, koda a gwargwadon ƙarfin, bai wuce 4 μg / ml ba.

Umarnin ya ce cikakkiyar ilimin halittarta a cikin marasa lafiya yana da kusan kashi 50-60%. Magungunan a zahiri ba a ɗaura su ga ƙwayoyin plasma. Abubuwan da ke aiki an cire su cikin fitsari gaba daya (100%) ba su canzawa. Abin da ya sa ba a ba da magunguna don marasa lafiya wanda adadin ƙirar su na gloalular filtration kasa da 60 ml / min.

Tabbatar da dan kuɗi na metformin ya fi 400 ml / min. Ya wuce ƙimar tacewar duniya. Wannan yana nufin cewa an cire siofor daga jiki ba wai kawai ta hanyar murƙushe dunƙule ba, har ma ta hanyar ɓoyayyen aiki a cikin tubules na proximal na koda.

Bayan gudanarwar baka, rabin rai yakai awoyi 6.5. Tare da gazawar koda, yawan fitowar siofor yana raguwa gwargwadon raguwa a cikin warwarewar ta hanyar creatinine. Don haka, rabin rayuwa yana tsawan rai kuma maida hankali na metformin a cikin jini yana tashi.

Shin Siofor yana cire alli da magnesium daga jiki?

Shin shan Siofor yana haifar da raunin magnesium, alli, zinc da jan ƙarfe a cikin jiki? Masana na Romania sun yanke shawarar ganowa. Nazarinsu ya shafi mutane 30 masu shekaru 30-60, waɗanda suka kamu da cutar sankarau ta 2 kuma waɗanda ba a yi musu magani ba a da. Anyi musu allurai Siofor 500 mg sau 2 a rana. Siofor kawai aka wajabta daga allunan don bin tasirin sa. Likitocin sun tabbatar da cewa kayayyakin da kowane mahalarta ya ci yana da kwayar magnesium guda 320 a rana. Allunan Magnesium-B6 ba a basu umarnin kowa ba.

Hakanan an kafa rukuni na sarrafawa daga mutane masu lafiya, ba tare da ciwon sukari ba. Sun yi gwaje-gwaje iri ɗaya don kwatanta sakamakon su da na masu ciwon sukari.
Marasa lafiya marasa lafiya na nau'in ciwon sukari na 2 wanda ke da gajiya koda, cirrhosis na hanta, psychosis, ciki, zawo na kullum, ko wanda ya ɗauki magungunan diuretic ba a yarda su shiga cikin binciken ba.

Yankin magnesium a cikin jinin marasa lafiya da ke dauke da ciwon sukari na 2 ya yi karanci, idan aka kwatanta da mutane masu lafiya. Rashin Magnesium a cikin jiki shine ɗayan abubuwan da ke haifar da ciwon sukari. Lokacin da ciwon sukari ya riga ya inganta, kodan suna cire sukari mai yawa a cikin fitsari, kuma saboda wannan, asarar magnesium yana ƙaruwa. Daga cikin masu ciwon sukari da suka ci gaba da rikice-rikice, akwai ƙarancin ƙwayar magnesium fiye da waɗanda ke da ciwon sukari ba tare da rikitarwa ba. Magnesium wani ɓangare ne na enzymes fiye da 300 waɗanda ke tsara yanayin metabolism, fats da carbohydrates. An tabbatar da cewa ƙarancin magnesium yana haɓaka juriya a cikin marasa lafiya da ke fama da cututtukan metabolism ko ciwon sukari. Kuma ɗaukar kari na magnesium, albeit dan kadan, amma har yanzu yana ƙaruwa da ƙwaƙwalwar sel zuwa insulin. Kodayake hanya mafi mahimmanci don magance juriya na insulin shine rage cin abinci na carbohydrate, duk wasu sun rage daga baya ta gefen nesa.

Zinc yana daya daga cikin mahimman abubuwan gano jikin mutum. Ana buƙatar fiye da matakai daban-daban 300 a cikin sel - aikin enzyme, ƙwayar furotin, alama. Zinc ya zama dole don tsarin garkuwar jiki yayi aiki, ya daidaita ma'aunin kwayoyin, ya kawar da radicals, rage jinkirin tsufa da hana cutar kansa.

Bakin karfe mahimmin abu ne mai ganowa, wani ɓangare na enzymes da yawa. Koyaya, ion jan karfe suna haɗuwa da haɓakar ƙwayoyin oxygen masu haɗari (masu tsattsauran ra'ayi), sabili da haka, sun kasance masu shayarwa. Dukkanin rashi da ƙarfe mara nauyi a jiki suna haifar da cututtuka iri iri. A wannan yanayin, wuce haddi ya fi yawa. Ciwon sukari na 2 wani cuta ne na rayuwa wanda ke haifar da juzu'ai masu yawa, wanda ke haifar da damuwa da iskar shaka domin lalata sel da jijiyoyin jini. Binciken da aka gudanar ya nuna cewa jikin masu ciwon suga yana yawan cika ta da jan karfe.

Akwai magunguna daban-daban da aka wajabta masu ciwon sukari na 2. Mafi mashahurin magunguna shine metformin, wanda aka sayar a ƙarƙashin sunayen Siofor da Glucofage. An tabbatar da cewa ba ya haifar da hauhawar nauyi, a'a yana taimakawa rage nauyi, inganta cholesterol jini, kuma duk wannan ba tare da cutarwa mai illa ba. Ana ba da shawarar Siofor ko mika glucophage don a tsara shi nan da nan, da zaran an gano mai haƙuri da ciwon sukari na 2 ko cutar sikari.

Likitocin Romania sun yanke shawarar amsa waɗannan tambayoyin:

• Menene matakin al'ada na ma'adanai da abubuwan abubuwan ganowa a jikin marasa lafiyar da aka gano kamuwa da cutar sukari ta 2? Babban, low ko al'ada?
• Ta yaya amfani da metformin zai shafi magnesium, alli, zinc da matakan ƙarfe?

Don yin wannan, sun auna a cikin masu ciwon sukari:

• maida hankali ne magnesium, alli, zinc da jan ƙarfe a cikin jini na jini;
• abun ciki na magnesium, alli, zinc da jan karfe a cikin awa 24 na fitsari;
• matakin magnesium a cikin sel jini (!);
• kazalika da "mai kyau" da kuma mummunan "cholesterol, triglycerides, azumi jini jini, glycated haemoglobin HbA1C.

Nau'in masu ciwon sukari na 2 da suka yi gwajin jini da fitsari:

• a farkon binciken;
• sannan kuma - bayan watanni 3 na shan metformin.

Abun da ke tattare da abubuwan ganowa a jikin mai haƙuri tare da nau'in ciwon sukari na 2 da kuma cikin mutane masu lafiya

Mun ga cewa a cikin marasa lafiya da ciwon sukari ana rage yawan sinadarin magnesium da zinc a cikin jini, idan aka kwatanta da mutane masu lafiya. Akwai kasidu da dama a cikin mujallolin likitanci na Ingilishi wadanda ke tabbatar da cewa karancin magnesium da zinc sune daya daga cikin sanadin cututtukan type 2. Copperarfe jan ƙarfe iri ɗaya ne. Don bayanin ku, idan kun dauki zinc a cikin allunan ko kifin, yana cike jiki da zinc kuma a lokaci guda yana fitar da ƙarfe mai yawa daga gare ta. Mutane kalilan sun san cewa sinadarin zinc yana da irin wannan tasirin. Amma ba kwa buƙatar kwashe ku sosai don babu ƙarancin jan ƙarfe. Zinauki zinc a cikin darussan sau 2-4 a shekara.

Sakamakon bincike ya nuna cewa shan metformin baya kara rashi abubuwan gano abubuwa da ma'adanai a cikin jiki. Saboda haɓakar magnesium, zinc, jan ƙarfe da alli a cikin fitsari a cikin marasa lafiya da ke da nau'in ciwon sukari na 2 bai karu ba bayan watanni 3. A gefen asalin magani tare da allunan Siofor, masu ciwon sukari suna ƙaruwa da sinadarin magnesium a cikin jiki. Marubutan binciken sun danganta wannan da aikin Siofor. Na gamsu da cewa kwayoyin hana daukar ciki ba su da wata alaƙa da ita, sai dai kawai mahalarta binciken sun ci abinci mafi ƙoshin lafiya yayin da likitocin suke dubansu.

Akwai yawancin jan ƙarfe a cikin jinin masu ciwon sukari fiye da mutanen da ke da lafiya, amma bambanci tare da ƙungiyar kulawa ba ta ƙididdiga ba. Koyaya, likitocin Romaniyan sun lura cewa yayin da aka samu ƙarfe a cikin jini na jini, to yakan sa ciwon ya kamu da wahala. Ka tuna cewa binciken ya ƙunshi marasa lafiya 30 masu fama da ciwon sukari na 2. Bayan watanni 3 na aikin likita, sun yanke shawarar barin 22 daga cikinsu a kan Siofor, kuma an ƙara ƙarin allunan 8 - Kalaman sulfonylurea. Saboda Siofor bai rage sukarinsu sosai ba. Wadanda suka ci gaba da kula da su tare da Siofor suna da 103.85 ± 12.43 mg / dl na tagulla a cikin jini, kuma waɗanda dole ne su tsara magunguna na sulfonylurea sun sami 127.22 ± 22.64 mg / dl.

Marubutan binciken sun tsayar kuma bisa kididdiga suka tabbatar da wadannan alamu:

• Shan Siofor a 1000 MG kowace rana baya kara fitar da sinadarin calcium, magnesium, zinc da jan karfe daga jiki.
• Yawancin magnesium a cikin jini, shine mafi kyawun karatun karatun glucose.
• A mafi yawan magnesium a cikin sel jini, mafi kyau aikin sukari da glycated haemoglobin.
• Copperarin yawan jan ƙarfe, mafi muni da aikin sukari, glycated haemoglobin, cholesterol da triglycerides.
• A sama da matakin glycated haemoglobin, da yawan zinc an kebe shi a cikin fitsari.
• Matsayi alli a cikin jini bai bambanta a cikin marasa lafiya da ke dauke da ciwon sukari na 2 da mutane masu lafiya.

Ina jawo hankalinku cewa gwajin jini don maganin magnesium bashi da amintacce, baya nuna rashi wannan ma'adinai. Tabbatar yin bincike kan abubuwan da magnesium yake a cikin sel jini. Idan wannan ba zai yiwu ba, kuma kuna jin alamun raunin magnesium a cikin jiki, to, kawai ɗauki allunan magnesium tare da bitamin B6. Babu lafiya sai dai idan kana da cutar koda. A lokaci guda, alli bashi da wani tasiri game da ciwon sukari. Tabletsaukar allunan magnesium tare da bitamin B6 da ƙwayoyin zinc sune lokuta da yawa da mahimmanci fiye da kalsiyam.

Aikin magunguna

Siofor - Allunan don rage sukarin jini daga rukunin biguanide. Magungunan yana ba da raguwa a cikin taro na glucose a cikin jini duka a kan komai a ciki da kuma bayan cin abinci. Ba ya haifar da ƙwancin ƙwayar cuta, saboda ba ya motsa ƙwayar insulin. Tabbatar da aikin metformin tabbas yana dogara ne akan hanyoyin da za'a bi:

• hana zubar da glucose mai yawa a cikin hanta ta hanyar hana gluconeogenesis da glycogenolysis, watau siofor yana hana hadawar glucose daga amino acid da sauran "albarkatun kasa", sannan kuma yana hana hakar shi daga shagunan glycogen;
• inganta tasirin glucose zuwa kasusuwa na ciki da kuma amfaninsa a wurin ta hanyar rage juriya daga kwayar halitta, wato, kashin jikin mutum ya zama mai hankali ga ayyukan insulin, sabili da haka sel suna “mamaye” glucose a jikin kansu;
• rage jinkirin shan glucose a cikin hanjin.

Ko da kuwa tasirin tasirin glucose a cikin jini, sinadarin siofor da sinadarin sa mai aiki suna inganta haɓakar lipid, yana rage abun cikin triglycerides a cikin jini, yana haɓaka sinadarin "kyakkyawan" cholesterol (babban yawa) kuma yana rage yawan kumburi mara kyau "mara kyau" a cikin jini.

Kwayar metformin ta kasance mai sauƙin hade cikin lipid bilayer na membranes cell. Siofor yana shafar membranes cell, gami da:

• hanawa na sarkar mitochondrial;
• increasedara yawan aikin tyrosine kinase na mai samun insulin;
• motsawa daga cikin jigilar mahaukacin glucose GLUT-4 zuwa membrane na jini;
• kunnawa na gina jiki protein na AMP.

Aikin kimiyyar halittar sel membrane ya dogara da iyawar abubuwan da suke cikin furotin don motsawa cikin yardar rai ba tare da lasa ba. Increaseara yawan ƙwaƙwalwar ƙwayar membrane shine sananniyar hanyar sankarar mellitus, wanda zai haifar da rikitarwa na cutar.

Nazarin ya nuna cewa metformin yana ƙaruwa da yawan ƙwayoyin plasma na sel jikin mutum. Muhimmiyar mahimmanci shine tasirin maganin a kan membranes na mitochondrial.

Siofor da Glucofage suna ƙaruwa da ƙwayar insulin mafi yawa daga sel tsokoki, kuma zuwa ƙarancin ƙarfi - nama mai daɗaɗa. Umarni a hukumance ya bayyana cewa maganin yana rage yawan shan glucose a cikin hanji da kashi 12%. Miliyoyin marasa lafiya sun tabbata cewa wannan magani yana rage ci. A bangon shan kwayoyin, jinin ba ya da kauri, yiwuwar samuwar cututtukan jini dake raguwa.

Glucophage ko siofor: me zaba?

Glucophage tsawo shine sabon tsarin sashi na metformin. Ya bambanta da siofor saboda yana da tasiri na tsawan lokaci. Magungunan daga kwamfutar hannu ba a tunawa da shi nan da nan, amma a hankali. A cikin Siofor na al'ada, an saki 90% na metformin daga kwamfutar hannu a cikin minti 30, kuma cikin glucophage mai tsawo - a hankali, sama da awanni 10.

Glucophage daidai yake da siophore, amma na tsawan aiki. Sidearancin sakamako masu illa kuma mafi dacewa don ɗauka, amma farashin yafi.

Idan mara lafiyar bai dauki siofor ba, amma glucophage mai tsawo, to ya isa ga matakin koli na metformin a cikin jini yana da hankali sosai.

Abvantbuwan amfãni na glucophage tsawon akan “saba” siofor:

• Ya isa ya ɗauke ta sau ɗaya a rana;
• sakamako masu illa daga cututtukan gastrointestinal tare da sashi guda na metformin ya inganta sau 2 sau da yawa;
• mafi kyau yana sarrafa sukari na jini yayin dare da safe akan komai a ciki;
• Sakamakon ragewan matakan glucose na jini ba ya yin muni da na siofor “na al'ada”.

Abin da za a zabi - siofor ko glucophage tsawon? Amsa: idan ba ku yi haƙuri da siofor ba saboda kumburi, ƙanƙara ko gudawa, gwada glucophage. Idan komai yayi kyau tare da Siofor, ci gaba da ɗaukar shi, saboda allunan tsayi na glucophage sun fi tsada tsada. Bernstein ya yi imanin cewa glucophage yana da inganci fiye da magungunan hanzari na metformin. Amma daruruwan dubban marasa lafiya sun gamsu da cewa siofor na al'ada suna aiki da ƙarfi. Sabili da haka, biyan ƙarin don glucophage yana da ma'ana, kawai don rage haushi da narkewa.

Sashi na allunan Siofor

An saita kashi na miyagun ƙwayoyi kowane lokaci daban-daban, gwargwadon matakin glucose a cikin jini da kuma yadda haƙuri ke haƙuri da magani. Yawancin marasa lafiya suna dakatar da maganin Siofor saboda rashin lafiya, zawo, da ciwon ciki. Sau da yawa, waɗannan sakamako masu illa ana haifar da su ta hanyar zaɓin marasa amfani kawai.

Hanya mafi kyau don ɗaukar Siofor ita ce tare da karuwa a kashi-kashi. Kuna buƙatar farawa da ƙarancin kashi - ba fiye da 0.5-1 g kowace rana ba. Waɗannan sune allunan 1-2 na miyagun ƙwayoyi na 500 MG ko kwamfutar hannu guda na Siofor 850. Idan babu tasirin sakamako daga jijiyoyin ciki, to bayan kwanaki 4-7 zaka iya ƙara yawan kashi daga 500 zuwa 1000 MG ko daga 850 MG zuwa 1700 MG kowace rana, i.e. tare da kwamfutar hannu guda ɗaya kowace rana zuwa biyu.

Idan a wannan matakin akwai sakamako masu illa daga hanji, to ya kamata “sake jujjuya” kashi zuwa na baya, daga baya kuma a sake kokarin kara shi. Daga umarnin don Siofor, zaku iya gano cewa ingantaccen maganin shine 2 MG a kowace rana, 1000 MG kowane. Amma sau da yawa ya isa ya sha 850 MG 2 a rana. Ga marasa lafiya na babban jijiya, mafi kyawun kashi na iya zama 2500 MG / rana.

Matsakaicin adadin kullun na Siofor 500 shine 3 g (Allunan 6), Siofor 850 shine 2.55 g (Allunan 3). Matsakaicin kullun na Siofor® 1000 shine 2 g (Allunan 2). Maximumarancin sa na yau da kullun shine 3 g (Allunan 3).

Ya kamata a ɗaukar allunan Metformin a kowane sashi tare da abinci, ba tare da taunawa ba, tare da isasshen adadin ruwa. Idan maganin da aka tsara yau da kullun ya fi kwamfutar hannu 1, raba shi zuwa allurai 2-3. Idan ka rasa shan kwayoyin, to bai kamata ka rama wannan ba ta hanyar ɗaukar ƙarin allunan sau ɗaya a gaba.

Tsawon lokacin da za a ɗauka Siofor - an ƙaddara wannan ta likita.

Yawan damuwa

Tare da yawan yawan maganin Siofor, acidosis lactate na iya haɓaka. Alamar ta: rauni mai ƙarfi, gazawar numfashi, amai, tashin zuciya, amai, gudawa, ciwon ciki, ƙarshen sanyi, rage karfin jini, raguwar bradyarrhythmia.

Ana iya samun koke-koke mai haƙuri na raɗaɗin tsoka, rikicewa da asarar hankali, saurin numfashi. Jiyya na lactic acidosis alama ce ta alama. Wannan rikitarwa ne mai haɗari wanda zai iya haifar da mutuwa. Amma idan bakayi girman maganin ba kuma tare da kodan naku komai yayi kyau, to yuwuwar sa kusan babu komai bane.

Hulɗa da ƙwayoyi

Wannan magani yana da dukiya na musamman. Wannan wata dama ce da za mu haɗu da ita tare da kowane sauran hanyoyi don rage taro na glucose a cikin jini. Ana iya yin maganin Siofor a haɗaka tare da kowane nau'in kwayar cutar sukari guda 2 ko insulin.

Ana iya amfani da Siofor a hade tare da magunguna masu zuwa:

• bayanan sirri (abubuwan da suka samo asali na sulfonylurea, meglitinides);
• thiazolinediones (glitazones);
• magungunan gargajiya (analogues / agonists na GLP-1, masu hana DPP-4);
• kwayoyi waɗanda ke rage shaye-shaye na carbohydrates (acarbose);
• insulin da kwayar ta.

Akwai ƙungiyoyi na kwayoyi waɗanda zasu iya inganta tasirin metformin akan rage sukarin jini, idan akayi amfani dasu lokaci guda. Waɗannan sune abubuwan da ake amfani da su na sulfonylurea, acarbose, insulin, NSAIDs, MAO inhibitors, oxygentetracycline, ACE inhibitors, Clofibrate Kalam, cyclophosphamide, beta-blockers.

Umarnin don Siofor ya ce wasu rukunin magunguna na iya rage tasirin sa ga ragewar sukari idan ana amfani da magunguna lokaci guda. Waɗannan su ne GCS, maganin hana haihuwa, epinephrine, sympathomimetics, glucagon, hormones thyroid, abubuwan asalin kwayoyin halittar phenothiazine, abubuwan nicotinic acid.

Siofor na iya raunana tasirin maganin ci gaban kai tsaye. Cimetidine yana rage jinkirin kawar da metformin, wanda ke kara haɗarin lactic acidosis.

Kada ku sha giya yayin da kuke shan Siofor! Tare da yin amfani da lokaci ɗaya tare da ethanol (barasa), haɗarin haɓaka rikitarwa mai haɗari - lactic acidosis yana ƙaruwa.

Furosemide yana ƙara yawan haɗarin metformin a cikin jini na jini. A wannan yanayin, metformin yana rage mafi girman taro na furosemide a cikin jini na jini da rabin rayuwarsa.

Nifedipine yana haɓaka ɗaukar matsakaicin ƙwayar metformin a cikin jini, yana jinkirta fitarwar.

Magungunan cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, vancomycin), waɗanda ke ɓoye a cikin tubules, gasa don tsarin jigilar tubular. Saboda haka, tare da tsawan magani, suna iya ƙara yawan haɗarin metformin a cikin jini.

A cikin labarin, mun tattauna daki-daki batutuwa masu zuwa:

• Siofor don asarar nauyi;
• Allunan da ke cikin allunan Metformin don rigakafi da magani na ciwon sukari na 2;
• A cikin waɗanne lokuta yana da kyau a sha wannan maganin don cutar guda 1;
• Yadda za a zabi sashi don babu damuwa narkewa.

Don nau'in ciwon sukari na 2, kada ku iyakance kanku ga shan Siofor da sauran magungunan, amma ku bi shirin na 2 na ciwon suga. Mutuwa da sauri daga bugun zuciya ko bugun jini shine rabin matsalar. Kuma zama mutum mai gado mai rauni a sanadiyyar cutar sankara yana da ban tsoro sosai. Koya daga gare mu yadda za a sarrafa ciwon sukari ba tare da abinci mai “fama da yunwa ba”, da karancin ilimin jiki da kuma a cikin kashi 90 zuwa 90 na lokuta ba tare da allurar insulin ba.

Idan kuna da tambayoyi game da maganin Siofor (Glucofage), to kuna iya tambayarsu a cikin maganganun, ginin yanar gizon yana amsawa da sauri.