Ofloxin 200 magani ne daga rukunin fluoroquinolones, babban wakilin maganin rigakafi. Wannan shi ne ɗayan magungunan rigakafi da aka saba amfani dasu da kuma amfani da su.
Sunan kasa da kasa mai zaman kansa
INN - Ofloxacin.
ATX
J01MA01.
Saki siffofin da abun da ke ciki
Akwai shi a cikin nau'ikan sashi daban-daban - mai kauri, ruwa, mai taushi. Yana da hanyoyi daban-daban na aikace-aikace. Aiki mai aiki na kowane nau'i shine ofloxacin, quinolone na ƙarni na II.
Ofloxin 200 magani ne daga rukunin fluoroquinolones, babban wakilin maganin rigakafi.
Kwayoyi
An rufe da kuma dauke da wani daban-daban adadin aiki manufa. Ofloxin Allunan, ban da aiki na kwayan kwayoyi na ofloxacin (200 da 400 MG kowannensu), sunada irin wannan ƙarin kayan aikin:
- sukari madara;
- sitaci masara;
- talc;
- hypromellose 2910/5.
Allunan an rufe su kuma suna dauke da wani daban-daban adadin aiki aiki.
Allunan sun bambanta a cikin sifa da ɗab'i suna nuna adadin babban abu (200 da 400 MG kowane). Kowane akwati yana dauke da tabar wiwi 1 dauke da Allunan 10
Saukad da kai
Hannun kunne da na ido ana samun su. 1 ml na ingantaccen bayani ya ƙunshi:
- 3 MG naloxacin;
- bayani mai gishiri;
- benzalkonium chloride;
- hydrogen chloride;
- ruwa mai shirya.
Sanya cikin kwalban filastik tare da dropper.
Ofloxin 200 yana samuwa a cikin nau'in kunne da faɗuwar ido.
Foda
Ba shi da wannan nau'in sakin.
Magani
Maganin don jiko na launuka masu launin shuɗi-kore ana cakuda su cikin 100 ml vials. Kwalban ya ƙunshi 200 MG na babban abu da kuma tsofaffi:
- bayani mai gishiri;
- Trilon B;
- hydrogen chloride;
- ruwa mai shirya.
Kafurai
Rawaya gelatin kwalliya mai launin shuɗi mai launin ruwan kasa ya ƙunshi:
- ofloxacin - 200 MG;
- hypromellose;
- sodium lauryl sulfate;
- sukari madara;
- alli phosphate bisubstituted anhydrous;
- foda talcum.
Rawaya gelatin capsules an cakuɗe a cikin blister of 10 guda.
Ana cakuda capsules a cikin blister of 10 guda.
Maganin shafawa
Ana amfani da maganin a cikin nau'i mai laushi - maganin shafawa don magance raunuka (Oflokain) da kuma maganin shafawa ido don kwanciya a cikin jaka mai sanyi. Maganin shafawa an cakuda a cikin shambura na 15 ko 30 a cikin g 1 na samfurin ya ƙunshi:
- 1 mg ofloxacin;
- 30 mg lidocaine hydrochloride;
- prolylene glycol;
- poloxamer;
- macrogol 400, 1500, 6000.
Ana samar da maganin shafawa a cikin shambura na 3 da 5, wanda ya ƙunshi:
- ofloxacin - 0.3 g;
- nipagin;
- nipazole;
- man fetur na jelly.
Ana amfani da maganin a cikin nau'i mai laushi - maganin shafawa don magance raunuka da maganin shafawa ido don kwanciya a cikin jakar jigilar jaka.
Kyandirori
Akwai magungunan ƙwayoyin cuta a ƙarƙashin sunayen iri daban-daban.
Aikin magunguna
Abubuwan da ke tattare da kwayoyin cuta na Ofloxin 200 sune saboda hanawar kwayar halitta ta DNA-gyrase - enzymes da ke da alhakin hada kwayar halittar DNA a sel na kwayan cuta da kuma haifuwar su. Wadannan tsoffin enzymes suna da hannu cikin matakai biyu masu mahimmanci - karkacewa da tabbatar da kwanciyar hankali. Fluoroquinolone yana ba da gudummawa ga lalata ƙwayar ƙwayar cuta, don haka haɗarin nau'ikan da ke da tsayayya suna da ƙasa.
Magungunan da suka fi aiki da ƙwayoyin cuta na gram. Ofloxin 200 manufa idan aka fallasa su topoisomerase II ne. Daga cikin rukuni na fluoroquinolones, miyagun ƙwayoyi sun shahara ga aikinta na musamman a kan cocci na gram. Manufarta ita ce topoisomerase IV.
Magungunan da suka fi aiki da ƙwayoyin cuta na gram-korau.
Magungunan magunguna na abu shine tushen lalata haɗin tsakanin helices na DNA (lalata shi), wanda ke haifar da mutuwar kwayar ƙwayar cuta. Irin wannan zaɓin ya haifar da shahararren ofloxacin da sauran fluoroquinolones - yawancin nau'ikan ƙwayoyin cuta masu tsayayya da sauran nau'ikan maganin rigakafi da sulfonamides suna ba da tasirin lalacewarsu.
Magungunan suna da ƙarancin adadin guba, as yana aiki ne kawai da kwayoyin halittar kwayar kwayar cuta, ba tare da lalata tsarin DNA na mutum ba. Sabili da haka, ana amfani da maganin a cikin aikin ilimin yara.
Pharmacokinetics
Magungunan suna cikin hanzari kuma ya ƙoshi cikin hanjinsa, har ya kai matakin da ya fi girma a cikin jini bayan sa'o'i 1-3. Abinci dan kadan yana hana tsarin sha, amma ba ya shafar cikar shi. Magungunan yana da ɗayan digiri mafi girma na digestibility tsakanin fluoroquinolones - kusan 100%.
Magungunan suna cikin hanzari kuma ya ƙoshi cikin hanjinsa, har ya kai matakin da ya fi girma a cikin jini bayan sa'o'i 1-3.
Rabin rayuwarsa shine awanni 5 zuwa 10, don haka ana iya shan miyagun ƙwayoyi sau 1-2 a rana. Mayar da hankali abu a cikin kyallen takarda daidai yake ko sama da tsinkaye. Idan ana gudanar da babban magani na magungunnan, to kayan sun tara a cikin:
- Tsarin juyayi na tsakiya;
- bututu na tagulla;
- jakar articular;
- tsarin urogenital;
- a cikin sel na rigakafi.
Saboda waɗannan kaddarorin, miyagun ƙwayoyi suna da tasiri a cikin maganin kamuwa da cuta cikin jijiya. Ofloxacin yana yin karancin canji a jikin mutum - kashi 75 - 90% na kayan an cire su ba a cikin fitsari ba, wanda yake da muhimmanci a lura da cututtukan da ya shafi kodan da hanjin karshin.
Abubuwan da ke gudana cikin jini na jini ba a ɗaure su da sunadarai ba kuma suna iya shiga cikin yardar rai daga gado na jijiyoyin jiki zuwa kyallen takarda.
Abubuwan da ke gudana cikin jini na jini ba a ɗaure su da sunadarai ba kuma suna iya shiga cikin yardar rai daga gado na jijiyoyin jiki zuwa kyallen takarda. Magungunan sun bambanta:
- tasiri a kowane pH;
- rashin tasiri a kan magunguna na methylxanthines;
- kasancewar aikin postantibiotic;
- ƙananan abin da ya faru na dysbiosis;
- ingantaccen bayanin martaba.
Abin da ke ciki baya tasiri cikin jijiyar ciki da tayi bayan tayi.
Alamu don amfani
An nuna don maganin cututtukan cututtuka:
- tsarin urinary;
- gabobin mace da na namiji;
- STI
- hanjin ciki;
- tsarin biliary;
- nosocomial da postoperative;
- na numfashi;
- septicemia da bacteremia;
- Tsarin juyayi na tsakiya;
- tarin fuka, kuturta.
Ana amfani da maganin shafawa don magance cututtukan fata, cututtukan hakori, da kuma kula da cututtukan da suka kamu.
Contraindications
Umarni a matsayin contraindication zuwa ga Ofloxin 200 yana nuna:
- rashin ƙarfi;
- ciki da lactation;
- far ga yara 'yan kasa da shekaru 18;
- amai da jijiyoyin wuya;
- kasancewar lalacewar jijiya saboda amfani da fluoroquinolones;
- cytosolic rashi enzyme (G6FD).
Tare da kulawa
A takaice dai an wajabta:
- cerebral arteriosclerosis;
- raunin jijiyoyin jini a cikin kwakwalwa;
- rashi mai aiki;
- ƙarancin ci gaba da yanayin tsarin juyayi na tsakiya;
- bugun kirji na zuciya tare da tsawaitawa tsakanin tsatstsauran QT.
An sake nazarin yawancin contraindications.
Yadda ake ɗaukar Ofloxin 200
An wajabta wa marasa lafiya manya 200-600 mg. Wannan tsawon lokacin shine 7-10 kwana. Za'a iya ɗaukar magani a cikin sashi na 400 MG sau ɗaya, zai fi dacewa da safe don rabin sa'a ko awa daya kafin cin abinci, an rarraba babban kashi zuwa kashi 2. An ba da shawarar haɗiye allunan gaba ɗaya da ruwa. A cikin cututtukan ƙwayar cuta mai ƙura da kiba, ana ba da izinin ƙaruwa har zuwa 800 MG / rana.
Idan cututtukan kumburi na ƙananan ƙwayar urinary (prostatitis, cystitis, urethritis) ba su da rikitarwa, to ya isa ya ɗauki 200 MG 1 sau ɗaya kowace rana don kwanaki 3-5. Don maganin cututtukan ƙwayar cuta, ana bada shawarar guda ɗaya na 400 MG.
Jigilar da tsarin kulawa a cikin marasa lafiya da gazawar koda ya dogara ne da tsaftacewar mahaɗan:
| Cl creatine (ml / min.) | Yawan abu (mg) | Swing (sau ɗaya a rana) |
| 50-20 | 200 | 2 |
| 400 | 1 | |
| < 20 | 200 - na farko | 1 |
| 100 | Kowane kwana 2 | |
| Hemodialysis, peritoneal dialysis | 100 | 2 |
Jiyya yana farawa ta hanyar gudanarwar cikin ciki kuma, bayan inganta yanayin, an wajabta kulawa ta baka a cikin sashi guda.
Game da tsallakewar kashi
Idan mara lafiyar ya manta shan maganin, to an yarda ya sha shi da zaran mai haƙuri ya tuna da shi.
Ana iya ɗaukar magani a cikin sashi na 400 MG sau ɗaya, zai fi dacewa da safe, rabin sa'a ko awa daya kafin cin abinci.
Shan maganin don ciwon sukari
Marasa lafiya da ke fama da cutar sankarau yayin gudanar da su tare da Ofloxin 200 suna buƙatar sarrafa glucose, saboda magani na lokaci daya tare da magunguna masu rage sukari, insulin da fluoroquinolones na iya tayar da hawan jini ko hyperglycemia.
Sakamakon sakamako na ofloxine 200
An yarda da maganin sosai - halayen da ba su dace ba sun zama kashi 0,5% na lokuta. Koyaya, ana lura da sakamako masu illa a wasu lokuta.
Marasa lafiya da ke fama da cutar sankarau yayin karatun tare da Ofloxin 200 suna buƙatar sarrafa glucose.
Gastrointestinal fili
Ciwo da rashin ciki, rashin lafiyar dyspeptik. M sosai:
- gastralgia;
- rashin cin abinci;
- hyperbilirubinemia;
- hepatitis.
Hematopoietic gabobin
Ana lura da amosanin ciki, leukopenia, pancytopenia, thrombocytopenia.
Tsarin juyayi na tsakiya
A cikin nau'in rashin jin daɗi, damuwa, rashin bacci. Da wuya bayyana:
- halin fidda rai ko tashin hankali;
- psychosis da phobias;
- pressureara yawan matsa lamba na intracranial;
- hallucinations;
- bacin rai
Daga tsarin musculoskeletal
Matsaloli da ka iya:
- tendonitis;
- rushewar tsoka;
- kumburi daga haɗin gwiwa da kayan aiki na ligamentous;
- rauni na tsoka da ciwo.
Daga tsarin numfashi
Ba alama.
A ɓangaren fata
A cikin nau'in petychia, rashes, dermatitis.
Daga tsarin kare jini
Da wuya a cikin hanyar:
- hypercreatininemia;
- fitar;
- kara urea.
Daga tsarin zuciya
Tsarin zuciya ya karye, saukar karfin jini yake raguwa, tasoshin jini ya yi zafi, rushewa yake yi.
Tsarin Endocrin
Ba'a gano shi ba.
Cutar Al'aura
Fatar jiki, ƙaiƙayi, gajeriyar numfashi, rashin lafiyar nephritis, kumburi fuska ko wuya, ƙwanƙwaran huhun ciki, huhun Quincke, girgiza ƙwayar cuta.
Tasiri kan ikon sarrafa abubuwan inji
Haramun ne a fitar da motocin kuma a yi aiki tare da hadaddun hanyoyin da ke buƙatar taro.
Bayan shan maganin, haramun ne a fitar da motocin.
Umarni na musamman
M ga pathologies lalacewa ta hanyar pneumococci ko mycoplasmas - mashako na kullum, ciwon huhu, mashako.
Idan akwai alamun rashin lafiyan, halayen da ba su dace ba daga tsarin juyayi na tsakiya, kuna buƙatar soke maganin.
A lokacin da ake amfani da farji, insolation, watsawar UV a cikin solarium da physiotherapy ya kamata a cire su.
Yi amfani da lokacin daukar ciki da lactation
Contraindicated saboda barazanar ci gaban pathologies na gidajen abinci da jijiyoyin cikin tayin. Lokacin shayarwa, yana da mahimmanci don canja wurin jariri zuwa tsarin jarirai.
Adana Ofloxin ga yara 200
Yara ba sa yin magani har sai girma da samuwar tsarin musculoskeletal ya cika. Koyaya, saboda dalilai na kiwon lafiya kuma a cikin rashin sakamako mai kyau ga sauran magungunan rigakafi, ana iya bi da Ofloxin 200 a sikelin na 7.5 a kowace kilo 1 na nauyin jiki. Matsakaicin izini shine 15 MG / kg.
Yara ba sa yin magani har sai girma da samuwar tsarin musculoskeletal ya cika.
Yi amfani da tsufa
An tsara shi a hankali saboda canje-canjen da suka danganci shekaru da haɗarin mummunan halayen.
Aikace-aikacen aiki mara kyau
Wajibi ne don daidaita sashi a ƙarƙashin kulawa da matakan ƙirar.
Amfani don aikin hanta mai rauni
Ana amfani da kayan aiki bisa kulawa ta yau da kullun game da adadin bilirubin, tare da karuwa a cikin kashi, ana daidaita wannan magani ko sokewa.
Idan akwai aiki na hanta mai rauni, ana amfani da maganin ta hanyar saka idanu akai-akai na adadin bilirubin.
Yawan abin da ya faru na Ofloxin 200
An lura da alamun cututtukan maye:
- bayyanuwar dyspepti;
- rashin haihuwa;
- rikicewa.
An soke maganin, an yi lavage na ciki. Tare da maye mai guba, hemodialysis mai yiwuwa ne.
Yin hulɗa tare da wasu kwayoyi
Yana hulɗa daban da kungiyoyi daban-daban na kwayoyi.
Abubuwan haɗin gwiwa
Kada ayi amfani da lokaci ɗaya tare da:
- NSAIDs - mai yiwuwa rage ƙarancin mashigar hanji;
- quinolones da kwayoyi tare da metabolism na koda - karuwa a cikin taro na ofloxin da tsawanta tsawon lokacin hutun nasa;
- jami'in antihypertensive, barbiturates - raguwa mai yawa a cikin karfin jini yana yiwuwa;
- glucocorticoids - haɗarin haɗarin tendonitis;
- anthocyanins - rage narkewar ƙwayar cuta;
- yana nufin cewa canza pH na fitsari zuwa gefen alkaline - tasirin nephrotoxic mai yiwuwa ne.
Ba da shawarar haɗuwa ba
Haramun ne a hada shi da:
- masu cutar bitamin K - masu yiwuwar karuwar coagulation na jini;
- Glibenkamide - na iya haɓaka taro na glibenclamide a cikin ƙwayar jini;
- yayin bincike, ƙwayar na iya ba da tabbatacciyar amsawa ga opiates da porphyrins a cikin fitsari.
Haɗuwa yana buƙatar taka tsantsan
An bayar da rahoton lokuta na ƙara yawan aiki na maganin anticoagulants na baki tare da lura na lokaci daya tare da fluoroquinolones.
Tare da gudanar da sabis na lokaci guda na kwayoyi waɗanda ke karya sinus, ana buƙatar sarrafa ECG.
Ofloxin 200 bai dace da ethylate ba.
Amfani da barasa
Amincewa da ethylate.
Analogs
Wadanda suka maye gurbin sun hada da: Ofaxin, Oflo, Floksan ,xtyagel, Ofor.
Magunguna kan bar sharuɗan
Saiti.
Zan iya saya ba tare da takardar sayan magani ba?
A'a.
Farashin Ofloxin 200
A cikin Ukraine - 133.38-188 UAH. A kan yankin Tarayyar Rasha - 160-180 rubles.
Magungunan magani ne.
Yanayin ajiya na miyagun ƙwayoyi
A cikin duhu, wuri mai sanyi, ba tare da danshi ba.
Ranar karewa
Bai wuce shekaru 3 ba.
Mai masana'anta
Jamhuriyar Czech.
Nazarin Ofloxin 200
Ya samu kyakkyawan bita daga likitoci da kuma marasa lafiya.
Likitoci
Maxim Alexandrovich, masanin ilimin uro, Minsk: "Duk cikin aikina na likita na kasance ina amfani da fluoroquinolones a cikin lura da marassa lafiya. Ina ganin Ofloxin 200 yana da tasiri. Yana bada sakamako mai kyau kuma ana jure shi ba tare da wata illa ba."
Galina Sergeevna, likitan ilimin mahaifa, Kiev: "A sau da yawa nakan sanya Ofloxin 200 ga marasa lafiya na da cututtukan urogenital. Kyakkyawan tsari ne, yana da kyau ku sarrafa da kuma kiyaye sashi. Yana da kyau ku kawai amfani da shi sau 1-2 a rana."
Marasa lafiya
Olga, mai shekaru 32, Kaluga: "An sha maganin ne yayin lura da cystitis. Na yi yawa. Bayan kwanaki da yawa na shan Ofloxin 200, alamu sun ɓace. Amma babu wasu sakamako masu illa, har ma da na yau da kullun bayan murkushe ƙwayoyin cuta."
Mikhail, ɗan shekara 22, Omsk: "Na kamu da sanyi a wurin aiki, an gano matsalolin ilimin urology.Likita ya ba da allunan magungunan Ofloxin 200 - sun yi aiki cikin sauri. An taimaka sosai. "
Tamara, mai shekara 40, Gorlovka: "Na sami mummunan gwaji don cututtukan bacci. A bisa shawarar likita, na dauki hanyar Ofloxin. Kwanan nan na sake komawa dakin gwaje-gwaje - sakamakon sakamako mara kyau ne. Komai na tafiya da sauri kuma ba tare da rikitarwa ba."
