Za'a iya amfani da miyagun ƙwayoyi azaman babban ma'aunin magani ko, tare da wasu hanyoyi don rikicewar zuciya. Wannan magani ne na antihypertensive, amma a lokaci guda an cire sauran yanayin cututtukan tare da taimakonsa. An samar dashi ta hanyar Allunan. Ana amfani da miyagun ƙwayoyi ta hanyar kunkuntar yanki na amfani.
Sunan kasa da kasa mai zaman kansa
Losartan.
ATX
Losartan C09CA01.
Za'a iya amfani da miyagun ƙwayoyi azaman babban ma'aunin magani ko, tare da wasu hanyoyi don rikicewar zuciya.
Saki siffofin da abun da ke ciki
Ana yin magungunan a cikin tsari mai ƙarfi. Potsafa losartan tana aiki azaman babban bangaren aiki. Mayar da hankali a cikin kwamfutar hannu 1 shine 50 MG. Sauran abubuwa marasa aiki:
- lactose monohydrate;
- microcrystalline cellulose;
- dankalin dankalin turawa;
- povidone;
- magnesium stearate;
- sitaci carboxymethyl sitaci;
- silicon dioxide colloidal.
Ana yin magungunan a cikin tsari mai ƙarfi.
Aikin magunguna
Babban aikin miyagun ƙwayoyi shine ikon daidaita matakin hawan jini. Ana bayar da wannan damar ne ta hanyar hana faruwar abubuwan tasirin ilimin halittar jiki wanda ke jawo ta hanyar ɗaurewar agonists da angiotensin II masu karɓa. Abubuwan da ke aiki a cikin abubuwan da ke tattare da Blocktran ba su tasiri enzyme kinase II, wanda ke ba da gudummawa ga halakar bradykinin (peptide saboda abin da tasoshin ke faɗaɗawa, raguwar hauhawar jini yana faruwa).
Bugu da kari, wannan bangaren ba ya shafar adadin masu karba (kwayoyin halittar jiki, tashoshin tashoshi) wadanda ke taimakawa ci gaban kumburi da sauran tasirin. A ƙarƙashin tasirin losartan, an lura da canji a cikin adrenaline, aldosterone a cikin jini. Bugu da kari, wannan sinadarin yana wakiltar gungun diuretics - yana inganta rashin ruwa a jiki. Godiya ga ƙwayoyi, an rage yiwuwar haɓaka hauhawar jini na mahaifa, marasa lafiya da ƙarancin aiki na zuciya sun fi haƙuri haƙuri da aiki na jiki.
Babban aikin miyagun ƙwayoyi shine ikon daidaita matakin hawan jini.
Pharmacokinetics
Amfanin wannan kayan aikin ya hada da sha da sauri. Koyaya, yadda ake amfani da shi ba ya ragu - 33%. Ana samun matsakaicin matakin tasiri bayan awa 1. A lokacin canji babban abu mai aiki, an saki metabolite mai aiki. Ana samun mafi girman tasirin magani bayan sa'o'i 3-4. Magungunan yana shiga cikin jini na jini, mai nuna alamun garkuwar furotin - 99%.
Losartan ba shi canzawa bayan sa'o'i 1-2. Metabolite yana barin jiki bayan awa 6-9. Mafi yawan magungunan (60%) ne hanjinsu ke kwance, sauran - tare da urination. Ta hanyar binciken asibiti, an gano cewa yawan haɗuwa a cikin babban abin da ke cikin plasma a hankali yana ƙaruwa. Ana samar da mafi girman sakamako mai guba bayan makonni 3-6.
Bayan kashi ɗaya, ana samun sakamakon da ake so yayin maganin bayan hoursan awanni. Hankalin losartan yana raguwa a hankali. Cire wannan kayan yana ɗaukar kwana 1. Don wannan, don samun sakamako mai warkewa, ana buƙatar ɗaukar miyagun ƙwayoyi a kai a kai, bin tsarin.
Mafi yawan magungunan (60%) ne hanjinsu ke kwance, sauran - tare da urination.
Alamu don amfani
An wajabta wakili don hauhawar jini. Sauran alamomi don amfani da Blocktran:
- rashin isasshen aikin zuciya cikin tsari na rashin lafiya, idan aka ba da cewa magani na baya tare da masu hana ACE ba su bayar da sakamakon da ake so ba, haka kuma a lokuta inda masu hana ACE ke bayar da gudummawa ga ci gaban halayen da ba su dace ba kuma ba zai yiwu a sha su ba;
- ci gaba da aiki da aikin na koda a cikin nau'in ciwon sukari na nau'in 2 na ciwon sukari, yana rage yawan ci gaban karancin wannan sashin.
Godiya ga miyagun ƙwayoyi, akwai raguwa a cikin yiwuwar ƙirƙirar dangantaka tsakanin cututtukan cututtukan zuciya da mace-mace.
Contraindications
Taƙaitawa kan amfani da Blocktran:
- rashin hankali ga kowane ɓangare na magungunan;
- da yawa yanayin yanayin cututtukan dabi'a: rashin haƙuri na lactose, cutar glucose-galactose malabsorption, rashi lactase.
An wajabta wakili don hauhawar jini.
Tare da kulawa
Idan cutar cututtukan zuciya, koda, bugun zuciya ko gazawar hanta (stenosis na arteries na kodan, hyperkalemia, da dai sauransu) sun kamu da cutar, lallai ne a yi amfani da maganin a karkashin kulawar likita, a hankali lura da jikin. Idan mummunan halayen ya faru, za a iya dakatar da hanyar neman lafiya. Waɗannan shawarwarin sun shafi lamuranda inda angioedema ta bunkasa ko rage karfin jini.
Yadda ake ɗaukar Blocktran
Girman yau da kullun shine kwamfutar hannu 1 tare da maida hankali akan abu mai aiki na 50 MG. Tare da hauhawar jini ba tare da kulawa ba, yana halatta a kara wannan adadin zuwa 100 MG kowace rana. An kasu kashi biyu ko kuma a sha sau ɗaya a rana. A cikin yanayi daban-daban na cututtukan cuta, kashi na farko na yau da kullun na iya ƙasa da haka:
- raunin zuciya - 0.0125 g;
- tare da magani na lokaci daya tare da diuretics, an wajabta magunguna a cikin sashi wanda ba ya wuce 0.025 g.
A cikin irin waɗannan adadi, ana ɗaukar magungunan har sati guda, sannan an ƙara ƙarancin ƙaramin. Wannan yakamata a ci gaba har sai an sami iyakar matsakaici na 50 MG.
Girman yau da kullun shine kwamfutar hannu 1 tare da maida hankali akan abu mai aiki na 50 MG.
Shan maganin don ciwon sukari
An ba da shawarar farawa tare da 0.05 g kowace rana. A hankali, kashi yana ƙaruwa zuwa 0.1 g, amma ya kamata koyaushe kula da matakin hawan jini.
Sakamakon sakamako na Blocktran
A mafi yawan halayen, ana ba da haƙuri ga wannan magani. Idan bayyanar cututtuka mara kyau sun bayyana, yawanci suna ɓacewa da kansu, yayin da babu buƙatar soke maganin. Sakamakon sakamako daga gabobin jijiya na iya haɓakawa: aiki mara kyau na gani, tinnitus, idanu masu ƙonewa, vertigo.
Gastrointestinal fili
Jin zafi a cikin ciki, matsi mai wahala, matattarar ruwa, canje-canje a narkewa, tashin zuciya da amai, haɓakar iskar gas, abubuwan lalacewa a ciki, bushewar baki.
Hematopoietic gabobin
Cutar ƙanƙanin ciki, ecchymosis, Shenplein-Genoch purple.
Tsarin juyayi na tsakiya
Ciwon kai, tsananin zafin zuciya, tashin hankali, tare da raunin fushwa. Tingling, karkacewar tunani (rashin kwanciyar hankali, fargabar tashin hankali da damuwa), hargitsi na bacci (rashin bacci ko rashin bacci), kasala, rawar jiki, rashi raguwa, rashi kwakwalwa, rashin tabin hankali da kuma rashi damuwa.
Bayan shan magungunan, ana iya jin zafi a ciki.
Daga tsarin urinary
Tabarbarewar Jima'i a cikin maza, wahalar urinating, da ƙarfi a cikin mutane masu lafiya, mai saurin kamuwa da ci gaban cututtuka.
Daga tsarin numfashi
Haushi, rhinitis, hanci, ambaliyar jini. Hakanan an lura da yawan cututtukan da ke kumburi: mashako, hanji, laryngitis.
A ɓangaren fata
Yawan bushewar fata, ƙoshi, erythema, fitsari, matsananciyar gashi, yana haifar da aski. Hyperhidrosis, rashes, dermatitis, da kuma ƙara yawan ji na haske suma an lura dasu.
Daga tsarin musculoskeletal
Myalgia, jin zafi a cikin gabobin, baya, kumburi hadin gwiwa, rauni na tsoka, arthritis, arthralgia, fibromyalgia.
Daga tsarin zuciya
AV toshe (digiri na 2), infarction na myocardial, hypotension na wata halitta daban (tsoka ko orthostatic), jin zafi a cikin kirji da vasculitis. Yawancin yanayin cututtukan cuta an lura dasu, tare da keta alfarmar zuciya: angina pectoris, tachycardia, bradycardia.
Daga tsarin zuciya, ana iya samun infarction na zuciya (myocardial infarction).
Cutar Al'aura
Cutar mahaifa, gajeriyar numfashi sakamakon haɓakar kumburin mahaifa, halayen anaphylactic.
Tasiri kan ikon sarrafa abubuwan inji
Babu ingantattun hani akan tuki. Koyaya, an bada taka tsantsan a wannan yanayin saboda yiwuwar haɓaka alamomin masu haɗari (ƙarancin sani, rashi, infarction na zuciya, da sauransu).
Umarni na musamman
Kafin fara magani, ana nuna marasa lafiya a bushewa. Yana da mahimmanci don kimanta yawan ƙwayoyin potassium.
Idan kun sha miyagun ƙwayoyi a lokacin daukar ciki (a cikin watanni na 2 da na 3), haɗarin mace-mace na mahaifa da jarirai suna ƙaruwa. Kwayar cuta mai saurin faruwa koyaushe tana faruwa a cikin yara.
Idan ma'aunin ruwa-mai rikicewar damuwa ya rikice, da alama yawan hypotension yana ƙaruwa.
Idan kun sha miyagun ƙwayoyi lokacin daukar ciki (a cikin kashi na biyu da na uku), hadarin mace tayi tayi yawa.
Tare da nau'in ciwon sukari na 2, hyperkalemia na iya faruwa.
Idan an gano mara lafiyar a cikin hyperaldosteronism na farko, ba a sanya magani a cikin tambaya ba, saboda a wannan yanayin ba za a iya samun sakamako mai kyau ba.
Yi amfani da lokacin daukar ciki da lactation
An haramta amfani da miyagun ƙwayoyi don amfani.
Taukar hoto na Blocktran don Yara
Ganin cewa ba a tabbatar da ingancin Blocktran ba, kuma ba a tabbatar da amincinsa ba, ya kamata ka guji shan wannan magani a cikin jiyya ga marasa lafiyar da ba su balaga ba.
Yi amfani da tsufa
A wannan yanayin, ba lallai ba ne a rage adadin maganin.
A cikin tsufa, ba lallai ba ne don rage yawan ƙwayoyi.
Aikace-aikacen aiki mara kyau
Ba a sake nazarin adadin ba, saboda sashin aiki mai aiki a cikin marasa lafiya da ke fama da cututtukan cututtukan wannan sashin lafiyar mutanen da ke cikin lafiyar mutane yana cikin jini a cikin adadin.
Amfani don aikin hanta mai rauni
Idan akwai tarihin likita na wannan sashin, ya kamata a sha miyagun ƙwayoyi a cikin adadi kaɗan, saboda yana da mallakin tarawa, wanda ke nufin ƙarfin aiki zai karu. Tare da ciwo mai tsanani, babu gwaninta tare da amfani, don haka ya fi kyau ka guji shan maganin.
Tarshen Babbar Jagora
Bayyanar cututtuka na faruwa:
- raguwa mai ƙarfi a cikin karfin jini;
- tachycardia;
- bradycardia.
Doarfewar yawa na Blocktran yana haifar da tachycardia.
Matakan da aka ba da shawarar jiyya: diuresis, far da nufin rage ƙarfi ko kuma cikakkiyar kawar da abubuwa marasa kyau. Cututtukan jiki a wannan yanayin ba shi da tasiri.
Yin hulɗa tare da wasu kwayoyi
Haramun ne a sha maganin a lokaci guda tare da sinadarin aliskiren da jami'ai dangane da shi, idan an gano mara lafiyar na dauke da cutar sankarar hanji ko kuma gazawar koda.
Haramun ne a dauki shirye-shiryen dauke da sinadarin potassium yayin jiyya tare da Blocktran.
Babu wasu maganganu mara kyau da amfani da maganin a lokaci daya tare da tambaya tare da hydrochlorothiazide, warfarin, digoxin, cimetidine, phenobarbital.
A ƙarƙashin rinjayar Rifampicin, an lura da raguwa a cikin yawan abubuwan aiki a cikin abun da ke ciki na Blocktran. Fluconazole yana aiki akan ka'idar iri ɗaya.
Haramun ne a dauki shirye-shiryen dauke da sinadarin potassium yayin jiyya tare da Blocktran.
Losartan yana rage yawan narkar da lithium.
Karkashin tasirin NSAIDs, tasiri na miyagun ƙwayoyi a cikin tambaya yana raguwa.
Tare da bayyanar cututtuka na ciwon sukari mellitus da gazawar koda, an hana yin amfani da aliskiren da magunguna dangane da shi yayin maganin tare da Blocktran.
Amfani da barasa
Abubuwan da ke aiki a cikin abun da ke cikin miyagun ƙwayoyi a cikin tambaya suna haifar da rikice-rikice masu rikitarwa idan aka yi amfani da su lokaci guda tare da abubuwan da ke tattare da giya.
Analogs
Sakonni:
- Losartan;
- Losartan Canon;
- Lorista
- Lozarel;
- Presartan;
- Blocktran GT.
Abin yarda ne idan aka yi la’akari da magungunan Rasha (Losartan da Losartan Canon) da kuma analogues na kasashen waje. Yawancin masu sayen sun fi son magunguna a cikin allunan, saboda sun dace don amfani: babu buƙatar bin ka'idodin tsabta don gudanar da maganin, babu buƙatar yanayi na musamman don gudanarwa, kamar yadda yake game da mafita. Allunan za'a iya ɗauka tare da ku, amma ana sake karanta sigar lokacin idan aka yi amfani da samfurin a wani fasalin.
Magunguna kan bar sharuɗan
Ana bayar da magani.
Zan iya siye ba tare da takardar sayan magani ba
Babu irin wannan damar.
Batun Blocktran
Kudin ya kai 110 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Shawarar yanayi na yanayi da aka ba da shawarar ya wuce + 30 ° С.
Ana bayar da magani.
Ranar karewa
An haramta amfani da wannan kayan aikin bayan shekaru 3 daga ranar samarwa.
Mai masana'anta
Pharmstandard-Leksredstva, Rasha.
Batun sake dubawa
Assessmentimar ƙwararrun masana da masu sayen kayayyaki muhimmin ma'auni ne yayin zaɓin magani. Anyi la'akari dashi tare da kaddarorin maganin.
Likitoci
Ivan Andreevich, likitan zuciya, Kirov
Magungunan suna hana wasu masu karɓar magani ne kawai, kuma ba ya shafar tsarin nazarin halittun da ke tabbatar da aiki na jiki na yau da kullun. Lokacin yin nadawa, ana yin la’akari da yanayin mai haƙuri da kuma kasancewar cututtukan haɗin gwiwa, tunda Blocktran yana da magungunan dangi da yawa.
Marasa lafiya
Anna, 39 years, Barnaul
Ina da hawan jini a rayuwata. Ina adana kaina da wannan kayan aiki. Kuma a cikin yanayi mai mahimmanci, wannan magani kawai yana taimakawa. Bayan kawar da bayyanuwar alamun bayyanar cutar hauhawar jini, Na ci gaba da shan magunguna don kula da matsin lamba a matakin al'ada. Sakamakon wannan magani yana da kyau kwarai.
Victor, mai shekara 51, Khabarovsk
Ina da ciwon sukari, don haka a hankali nake amfani da wannan maganin. Allunan zasu iya rage karfin jini idan kun sha wani abu wanda ya zarce wanda aka bada shawara. Amma har yanzu ban sami wani zaɓi a tsakanin kwayoyi tare da irin wannan babban matakin tasiri ba, Ina amfani da Blocktran. Na kuma gwada kayan abinci, amma ba sa ba da sakamako kwata-kwata.
