Actovegin 200 magani ne na asalin dabbobi. An dauki jinin matasa shanun a matsayin tushen maganin yayin ayyukan samarwa. Magungunan yana cikin rukunin magunguna na rayuwa waɗanda ke dacewa da amfani da sukari da ƙwayar oxygen. Shan miyagun ƙwayoyi yana rage haɗarin haɓakar yunwar oxygen da ke cikin ƙwayoyin sel kuma yana taimakawa wajen daidaita matakan rayuwa a cikin jiki.
Sunan kasa da kasa mai zaman kansa
Actovegin. A cikin Latin - Actovegin.
Actovegin 200 magani ne na asalin dabbobi.
ATX
B06AB.
Saki siffofin da abun da ke ciki
Actovegin yana samuwa a cikin sashi na maganin allura kuma a cikin nau'ikan allunan.
Kwayoyi
Fuska a jikin allunan ya kunshi fim na kayan jikin mai dauke da launi mai launin shuɗi, mai dauke da:
- cacacam gum;
- sucrose;
- povidone;
- titanium dioxide;
- kudan zuma glycol wax;
- talc;
- macrogol 6000;
- hytromellose phthalate da dibasic ethyl phthalate.
Rinar launin rawaya Quinoline da varnish na aluminihu suna ba da takamaiman inuwa da haske. Tushen kwamfutar hannu ya ƙunshi 200 MG na kayan aiki mai aiki dangane da jinin maraƙi, kazalika da microcrystalline cellulose, talc, magnesium stearate da povidone azaman ƙarin mahadi. Unitsungiyoyi na miyagun ƙwayoyi suna da siffar zagaye.
Daya daga cikin nau'ikan sakin Actovegin shine Allunan.
Magani
Maganin yana kunshe da ampoules gilashin milimita 5 wanda ya ƙunshi 200 MG na fili mai aiki - Actovegin maida hankali, wanda aka samo daga jinin haiato na jinin maraƙi, an warware shi daga ƙwayoyin furotin. Ruwan baƙin ciki don yin allura azaman ƙarin kayan abinci.
Aikin magunguna
Actovegin yana cikin hanyar hana ci gaban haipoxia. Samun magungunan ya ƙunshi dialysis na jinin shanu da karɓar hemoderivat. Abubuwan da aka zubar da hankali a matakin masana'antar suna haifar da hadadden kwayoyi masu nauyin kilogram 5000. Irin wannan kayan aiki mai guba ne kuma yana da tasirin sakamako 3 akan jiki kwatancen:
- na rayuwa
- inganta microcirculation;
- neuroprotective.
Yin amfani da miyagun ƙwayoyi yana shafar safarar ruwa da sikari na sukari saboda aikin phosphoric cyclohexane oligosaccharides, waɗanda suke ɓangare na Actovegin. Saurin amfani da glucose yana taimakawa haɓaka ayyukan mitochondrial na sel, yana haifar da raguwa a cikin kira na lactic acid a kan asalin ischemia kuma yana ƙara haɓaka metabolism.
Actovegin yana cikin hanyar hana ci gaban haipoxia.
Tasirin neuroprotective na miyagun ƙwayoyi shine saboda hanawar apoptosis na ƙwayoyin jijiya a cikin yanayin damuwa. Don rage haɗarin mutuwar neuronal, miyagun ƙwayoyi suna hana ayyukan beta-amyloid da fassarar kappa-bi, suna haifar da apoptosis da kuma daidaita tsarin kumburi a cikin jijiyoyin jijiyoyin jijiyoyin jiki.
Magungunan suna da tasiri sosai akan tasirin tasirin tasoshin jijiyoyin, yana daidaita tsari na microcirculation a cikin kyallen.
Pharmacokinetics
Sakamakon binciken magunguna, kwararru sun kasa tantance lokacin da za a kai ga mafi yawan abubuwan da ke aiki a cikin jini, rabin rayuwa da kuma hanyar shakatawa. Wannan shi ne saboda tsarin hemoderivative. Tunda abu ya ƙunshi ƙananan ƙwayoyin halittun da ake gabatarwa a cikin jikin mutum, ba shi yiwuwa a tantance ainihin ma'aunin magunguna. Tasirin warkewa yana bayyana rabin sa'a bayan gudanar da maganin baka kuma ya kai matsakaici bayan awanni 2-6, gwargwadon halayen mutum na haƙuri.
A cikin aiwatar da tallan bayan-bayan, ba a sami lokuta na rage tasirin miyagun ƙwayoyi a cikin marasa lafiya da gazawar renal.
A cikin aiwatar da tallan bayan-bayan, ba a sami wani lokuta na rage tasirin miyagun ƙwayoyi a cikin marasa lafiya da keɓaɓɓiyar renal ko rashin hepatic.
Abin da aka wajabta
An tsara miyagun ƙwayoyi a matsayin wani ɓangare na hadaddun farji a cikin waɗannan lambobin:
- haɗarin mahaifa;
- cutar waƙa
- rikicewar wurare na gefe;
- post-traumatic jijiyoyin cuta cuta a cikin kwakwalwa;
- raguwa bayan bugun jini a cikin ayyukan fahimta;
- ciwon sukari polyneuropathy.
Ana amfani da miyagun ƙwayoyi don lalacewar tashoshi na jijiya da jijiyoyi kuma ga rikice-rikice (haɓakar cututtukan trophic, vasopathy).
Contraindications
Magungunan yana contraindicated a cikin mutane tare da ƙara mai saukin kamuwa zuwa aiki da ƙarin abubuwa Actovegin da sauran kwayoyi na rayuwa. Wajibi ne a tuna da abun ciki na sucrose a cikin kwasfa na jikin allunan, wanda ke hana gudanarwar Actovegin ga mutane masu shan gulukor-galactose sha ko tare da rashin jituwa na fructose. Ba'a bada shawarar miyagun ƙwayoyi don rashi na sucrose da isomaltase.
Tare da kulawa
Wajibi ne a kula da yanayin jijiyoyin bugun jini ga mutanen da ke da rauni na zuciya ko rauni ko guda biyu ko uku. Yakamata a yi taka tsantsan idan akwai cututtukan huhun ciki, cututtukan fata da oliguria. Sakamakon warkewa na iya raguwa tare da hauhawar jini.
Wajibi ne a kula da yanayin jijiyoyin bugun jini ga mutanen da ke da rauni na zuciya ko rauni ko guda biyu ko uku.
Yadda ake ɗaukar Actovegin 200
Allunan ana daukar su a baki kafin abinci. Karka tauna maganin. An saita sashi gwargwadon nau'in cutar sankara.
Ana magance maganin a cikin / a ko / m.
| Cutar | Tsarin warkewa |
| Damuwa | Ana shan allunan 2 sau 3 a rana don watanni 5. |
| Cututtuka na wurare dabam dabam na jini, gami da cututtukan cuta tare da rikitarwa | Adadin yau da kullun shine daga 600 zuwa 1200 MG don gudanarwa sau 3 a rana. Farjin yana wuce makonni 4-6. |
| Hadarin Cerebrovascular | 5-25 ml iv bayani na kwanaki 14, tare da ɗaukar allunan tare da sashi gwargwadon halayen mutum na haƙuri. |
| Matsanancin rauni na bugun jini na ischemic. An wajabta magungunan don kwanakin 5-7 na maganin. | Ruwa na ciki na 2000 MG kowace rana. Ana aiwatar da aikin har zuwa 20 infusions, tare da sauyawa zuwa shan Allunan (raka'a 2 sau 3 a rana). Jimlar magani shine makonni 24. |
| Yankakken angiopathy | 20-30 ml na miyagun ƙwayoyi an narke shi tare da maganin isotonic 0.9%. An gabatar da iv har tsawon wata daya. |
| Ischemic bugun jini | 20-50 ml na Actovegin an narke su da 200-350 ml na ilimin kimiya na jiki 0.9% sodium chloride bayani ko 5% glucose. Ana sanya droppers har sati guda, bayan haka an rage yawan maganin Actovegin zuwa 10-20 ml kuma an sanya shi azaman jiko na makonni 2. Bayan ƙarshen magani tare da mafita, sun canza zuwa ɗaukar hanyar kwamfutar hannu. |
| Radiation cystitis | Ana sarrafa 10 ml na maganin a cikin transurethrally a hade tare da maganin rigakafi a cikin kudi na 2 ml / min. |
| Sabuntawa cikin sauri | 10 ml na maganin yana cikin allura ko allura tare da 5 ml na Actovegin. Dogaro da dawo da nama, ana iya gudanar da maganin a kowace rana ko kuma lokaci-lokaci sau 3-4 a mako. |
| Jiyya da rigakafin cututtukan farji (na fata da ƙwayoyin mucous) | 5 ml iv. |
Shan maganin don ciwon sukari
Game da ciwon sukari na polyneuropathy, ana bayar da shawarar shigar da jijiyoyin ƙwayar cuta na ƙwayar cuta ta yau da kullun na 2000 mg. Bayan masu digiri 20, miƙa mulki ga bakin magana na kwamfutar hannu na Actovegin ya zama dole. An wajabta 1800 MG kowace rana tare da yawan sarrafawa sau 3 a rana don allunan 3. Tsawan lokacin magani yana bambanta daga watanni 4 zuwa 5.
Game da ciwon sukari na polyneuropathy, ana bayar da shawarar shigar da jijiyoyin ƙwayar cuta na ƙwayar cuta ta yau da kullun na 2000 mg.
Side effects
Abubuwan da ba su dace ba game da miyagun ƙwayoyi na iya haɓaka sakamakon yawan zaɓin da aka zaɓa ba daidai ba ko kuma tare da cin zarafin miyagun ƙwayoyi.
Daga tsarin musculoskeletal
Wakili na rayuwa na yau da kullun na iya shafan metabolism, wanda ke rikicewa tare da ɗaukar ions na alli. A cikin marasa lafiyar da aka riga aka ƙaddara, haɗarin bunkasa gout yana ƙaruwa. A wasu halaye, bayyanar rauni rauni da jin zafi.
A ɓangaren fata
Tare da gabatarwar miyagun ƙwayoyi a cikin murfin tsoka ko cikin jijiya, redness, phlebitis (kawai tare da jiko na iv), tashin zuciya da kumburi a wurin da aka sanya allura na iya faruwa. Tare da ƙara yawan ji na Actovegin, urticaria ya bayyana.
Daga tsarin rigakafi
Lokacin ɗaukar wakili na rayuwa, amsar rigakafi da adadin leukocytes a cikin jiki na iya raguwa yayin kamuwa da cuta mai yaduwa.
Cutar Al'aura
A cikin marasa lafiya tare da tashin hankali na nama, cututtukan fata da zazzabi na ƙwayoyin cuta na iya haɓaka. A cikin lokuta mafi saukin yanayi, angioedema da tashin hankali anaphylactic na iya faruwa.
Umarni na musamman
Lokacin yin allurar cikin ciki, kana buƙatar sannu a hankali shigar da mafita zuwa cikin ƙwayar tsoka mai zurfi. Yawan maganin ba zai wuce 5 ml ba. Marasa lafiya sun ƙaddara aukuwar halayen anaphylactic, ya zama dole a saka gwaje-gwajen ƙura tare da gabatarwar 2 ml / m don gano haƙuri ga miyagun ƙwayoyi.
Iya warware matsalar yana da launin toka mai launin shuɗi. Ynamarfin ƙarfi gamut mai launi na iya bambanta dangane da tsari da aka saki da adadin abubuwan haɗin ginin da suke ciki. Waɗannan fasalulluka basa cutar da ƙwayoyin jikin mutum kuma basu rage haƙuri da ƙwayoyi ba. Sabili da haka, lokacin sayen, babu buƙatar mayar da hankali kan launi na mafita, amma baza ku iya amfani da wani ruwa mai dauke da barbashi mai kauri ba.
Ampoule budewa ba batun ajiya bane.
Amfani da barasa
Yayin magani tare da Actovegin an hana shi amfani da barasa. Ethanol ya sami damar rage tasirin metabolism da neuroprotective saboda hanawa da tsarin juyayi na tsakiya.
Tasiri kan ikon sarrafa abubuwan inji
Magungunan ba ya shafar aikin neuromuscular na aiki. A kan tushen aikin yau da kullun na tsarin juyayi na tsakiya da tsokoki na kasusuwa, ba a hana mai haƙuri yayin tuki tare da Actovegin daga tuki ba, shiga cikin ayyukan da ke buƙatar babban ƙarfin hali da maida hankali, da kuma sarrafa kayan haɗin kayan aiki.
Lokacin da ake jiyya tare da Actovegin, ba a hana mota ba.
Yi amfani da lokacin daukar ciki da lactation
Ba a haramta amfani da miyagun ƙwayoyi don amfani da mata masu juna biyu ba. Abubuwan da ke aiki ba zai shiga cikin hanawar haiatoplacental ba, wannan shine dalilin da yasa baya haifar da wata barazana ga cigaban tayin mahaifa. Za'a iya haɗa magungunan a cikin haɗuwa don maganin cututtukan ƙwayar cuta na preeclampsia ko babban yiwuwar ashara.
Ba a kwance damarar jinin haila ta hanyar glandar mammary ba, saboda haka, yayin maganin shayarwa, ana iya shayar da nono.
Sashi Actovegin 200 yara
An hana jarirai da jarirai su ba Allunan Actovegin saboda karuwar haɗarin kamuwa da jini. Injewa yana ba ka damar shiga miyagun ƙwayoyi cikin jikin yara da ƙara haɓaka abubuwan aiki. An saita sashi ne ta likitan halartar gwargwadon nauyin jikin yaron. An ba da shawarar cewa ana kulawa da jarirai da jarirai Actovegin sau ɗaya a rana a cikin kashi / in ko a / m a cikin nauyin 0.4-0.5 a kowace kilo 1 na nauyi.
Don yara daga shekara 1 zuwa 3, ana iya ƙara yawan sashi na miyagun ƙwayoyi zuwa 0.6 ml / kilogiram na jiki a jiki, yayin da ga yaro daga shekaru 4 zuwa 6, ana amfani da maganin baka ko gudanar da 0.25-0.4 ml / kg intramuscularly ko intravenously an yarda kowace rana. Lokacin shan magani a ciki, kuna buƙatar ba wa ¼ allunan kwamfutar hannu. Sakamakon rabuwar nau'in sashi, ana rage tasirin maganin.
Yi amfani da tsufa
Actovegin baya buƙatar canje-canje a cikin tsarin sashi lokacin da aka wajabta shi ga mutanen da suka wuce shekaru 60.
Actovegin baya buƙatar canje-canje a cikin tsarin sashi lokacin da aka wajabta shi ga mutanen da suka wuce shekaru 60.
Yawan damuwa
A yayin binciken bincike na yau da kullun, an gano cewa Actovegin, lokacin da ya wuce shawarar da aka bayar da shawarar ta hanyar sau 30-40, ba shi da tasiri mai guba kan tsarin gabobin jikin mutum da ƙirar jikin mutum. A lokacin cinikin bayan-farashi a cikin aikin asibiti, ba a sami adadin cutar da aka yi yawa ba.
Yin hulɗa tare da wasu kwayoyi
Tare da kulawar cikin ciki na Mildronate da Actovegin, yana da mahimmanci a lura da tazara tsakanin injections na sa'o'i da yawa, saboda ba a bayar da rahoton ko magungunan suna hulɗa da juna ba.
Wakili na rayuwa yana tafiya da kyau tare da Curantil don maganin gestosis (cuta na jijiyoyin zuciya) a cikin mata masu juna biyu waɗanda ke da haɗarin haihuwa.
Haɗuwa yana buƙatar taka tsantsan
Tare da amfani da layi daya na amfani da Actovegin da ACE inhibitors (Captopril, Lisinopril), ana bada shawara don saka idanu akan yanayin haƙuri. An ƙulla maganin hana ƙwayoyin enzyme mai canzawa tare da wakili na rayuwa don inganta wurare dabam dabam na jini a cikin isyomic myocardium.
Yakamata a yi taka tsantsan yayin alƙawarin Actovegin tare da daskararren ƙwayoyin potassium.
Analogs
Sauya miyagun ƙwayoyi in babu tasirin warkewa zai iya zama magunguna tare da kaddarorin magunguna iri ɗaya, gami da:
- Vero-Trimetazidine;
- Cortexin;
- Cerebrolysin;
- Makasantanta.
Wadannan kwayoyi suna da rahusa a cikin farashin farashin.
Yanayin hutu Actovegin 200 daga kantin magani
Ba a sayar da magani ba tare da takardar sayen magani ba.
Zan iya siye ba tare da takardar sayan magani ba
An tsara maganin ne kawai don dalilai na likita kai tsaye, saboda ba shi yiwuwa a ƙayyade tasirin Actovegin akan mutum mai lafiya.
Farashi
Kudin a cikin kantin magunguna a Rasha ya bambanta daga 627 zuwa 1525 rubles. A cikin Ukraine, ƙwayar ta kashe kimanin 365 UAH.
Yanayin ajiya na miyagun ƙwayoyi
Wajibi ne don adana maganin a zazzabi wanda bai wuce + 25 ° C ba.
Ranar karewa
Watanni 36.
Mai ƙera Actovegin 200
Takeda Austria GmbH, Austria.
An hana jarirai da jarirai su ba Allunan Actovegin saboda karuwar haɗarin kamuwa da jini.
Nazarin likitoci da marasa lafiya akan Actovegin 200
Mikhail Birin, Likita, Nema, Vladivostok
Ba a sanya magani ba azaman maganin monotherapy, saboda haka yana da wahala magana game da tasiri. Abubuwan da ke aiki shine maganin hemoderivative, wanda shine dalilin da ya sa ya zama dole a lura da yanayin mai haƙuri: ba a bayyana yadda aka tsabtace maganin ba yayin samarwa, menene sakamakon zai kasance daga amfani. Marasa lafiya suna haƙuri da maganin sosai, amma na fi so in amince da samfuran roba. A lokuta da wuya, ciwon kai na iya faruwa.
Alexandra Malinovka, dan shekara 34, Irkutsk
Mahaifina ya bayyana thrombophlebitis a cikin kafafu. Gangrene ya fara, kuma dole ne a yanke qafar. Halin da ake ciki ya rikitar da ciwon sukari mellitus: salon mai warkarwa ya warkar da talauci kuma yana narkarda kullun tsawon watanni 6. Nemi taimako a asibiti, inda ake gudanar da Actovegin cikin hanzari. Yanayin ya fara inganta.Bayan fitowar, mahaifin ya dauki allunan Actovegin da allurar ciki na 5 ml a hankali bisa ga umarnin don amfani. Raunin a hankali ya warke har tsawon wata daya. Duk da babban farashin, Ina tsammanin magungunan suna da tasiri.
