Ciprolet 500 shine ɗayan ingantattun magungunan fluoroquinolone tare da aikace-aikace masu yawa. Ana iya amfani dashi don magani da rigakafin cututtuka daban-daban da cututtuka, amma kafin fara magani, ana ba da shawarar tabbatar da yiwuwar ƙwayoyin ƙwayoyin cuta zuwa wannan ƙwayar cuta.
ATX
Magungunan yana cikin rukunin magunguna na quinolones kuma yana da lambar ATX na J01MA02.
Ciprolet 500 shine ɗayan ingantattun magungunan fluoroquinolone tare da aikace-aikace masu yawa.
Saki siffofin da abun da ke ciki
Cyprolet an yi shi ne a siffofin sashi mai zuwa:
- kwamfutar hannu mai rufi;
- jiko bayani;
- ido ya sauke.
Kamar yadda abu mai aiki, ana amfani da ciprofloxacin a cikinsu.
Magani na 500 MG yana da nau'in kwamfutar hannu kawai na maganin. Allunan suna da fari, zagaye, convex a garesu. Abun da ke aiki mai aiki a cikin hanyar hydrochloride yana nan a cikin adadin 0.25 ko 0.5 g. Babban ma ya hada da:
- croscarmellose sodium;
- microcellulose;
- magnesium stearate;
- silicon dioxide;
- magungunan talc;
- sitaci masara.
Ana yin murfin fim ɗin ne daga cakuda hypromellose, dimethicone, titanium dioxide, macrogol, talc, sorbic acid da polysorbate.
Allunan 10 rarraba a cikin blisters. Kayan katako na waje. An saka farantin furen 1 da umarnin yin amfani da shi.
Ana amfani da Ciprolet azaman ƙwayar ƙwayar cuta.
Aikin magunguna
Ana amfani da Ciprolet azaman ƙwayar ƙwayar cuta. Abubuwan da ke aiki da su shine ciprofloxacin, kwayar roba ta jerin kwayoyin fluoroquinolone. Hanyar aiwatar da wannan kwayar shine hanawar topoisomerases na nau'in II da IV, wanda ke da alhakin samar da kwayoyin halittar DNA.
Kwayoyin rigakafi suna nuna kaddarorin kwayoyin. A ƙarƙashin tasirin sa, an toshe halittar DNA, ci gaba da haɓaka ƙwayoyin cuta, an lalata membranes da membranes cell, wanda ke haifar da mutuwar ƙwayoyin cuta. Wannan yana ba ku damar lalata cututtukan gram-korau waɗanda ke cikin aiki da kuma hutawa. Magungunan kuma suna aiki akan cututtukan gram-tabbatacce, amma kawai lokacin da suke kan matakin haifuwa.
Ciprofloxacin baya nuna juriya-kwayar kwayoyi tare da penicillins, aminoglycosides, tetracyclines, cephalosporins da sauran maganin rigakafi waɗanda basa toshe kwayar halittar DNA. Saboda haka, yana aiki yadda yakamata a inda waɗannan kwayoyi suka kasa. Yana aiki a kan cututtukan ƙwayoyin cuta da yawa, gami da:
- Moraxella catarrhalis;
- Salmonella
- Shigella
- neiseries;
- Klebsiella;
- Kare
- listeria;
- brucella;
- entero da cytobacteria;
- tsawa;
- hanjin ciki, hawan jini, Pseudomonas aeruginosa;
- chlamydia
- wasu staph da streptococci.
Fecal enterococcus da Mycobacterium avium suna buƙatar yin amfani da miyagun ƙwayoyi a allurai masu yawa. Ba shi da inganci a kan cututtukan ƙwayar cuta, ƙwararrun ƙwayoyin cuta, ureaplasma, mycoplasma, bacteroids, flavobacteria, Pseudomonas maltophilia, Clostridium difficile, Nocardia asteroides, yawancin anaerobes, ba sa cinikin hanji na halitta da microflora na farji.
Resistance na iya bambanta tsawon lokaci kuma ya dogara da yanayin ƙasa. Samun juriya yana haɓaka a hankali.
Pharmacokinetics
Kwayar mai aiki tana karɓar daga ƙananan hanji, har zuwa mafi girman taro a cikin jini 1-2 sa'o'i bayan ɗaukar allunan. Abinci yana rage ƙimar sha, amma ba ya shafar bioavailability, wanda zai iya kaiwa 80%. Kwayar rigakafi ta shiga cikin ruwa mai yawa (peritoneal, ophthalmic, bile, fitsari, yau, lemun tsinkaye, synovia, sputum, plasma seminal), an rarraba shi sosai cikin kyallen:
- hanta
- mafitsara;
- gabobin haihuwa;
- hanji;
- peritoneum;
- a cikin prostate;
- huhu da pleura;
- koda da urinary fili;
- gidajen abinci;
- Tsarin tsoka da fata.
A lokaci guda, tarawar nama sau da yawa (har zuwa 12) ya fi wanda ke jini.
Magungunan zai shiga cikin madarar nono, ya ketare mahaifa da katangar jini. Abinda ke ciki na ciprofloxacin a cikin ƙwayar cerebrospinal in babu wani tsari mai kumburi ya kai kimanin 8% a cikin jini, kuma tare da ɓoyewar meninges zai iya kaiwa 37%. Sadarwa tare da kariyar jini - 20-40%.
Yankan aiki da magungunan Ciprolet 500 an yi shi ta hanta, metabolites yana nuna wasu aiki.
Sashi na aiki da miyagun ƙwayoyi ana gudanar da shi ta hanta, metabolites yana nuna wasu aiki. Har zuwa 70% na kashi da aka ɗauka an nuna shi ta asali. Babban nauyin cirewa ya fadi akan kodan. Cutar da rabin rayuwar shine awa 3-6. A cikin gazawar koda kodayaushe, wannan manuniya na iya ninka biyu, amma magani ba ya tarawa, tunda an inganta haɓakar kansa ta hanji. Tare da aikin koda na al'ada, ana kwashe filaye 1% na ƙarar farko.
Abinda ya taimaka
Magungunan da ke cikin tambaya an yi niyya don yaƙar microflora na pathogenic, wanda ke kula da ciprofloxacin. Alamu don alƙawarin Cyprolet:
- Ciwon ƙwayar cuta na ƙwayar cuta: matsanancin ƙwaƙwalwar ƙwayar cuta, mashako, bronchiectasis, ƙwayar ƙwayar ƙwayar cuta, idan ba a haifar da ita ba ta hanyar cututtukan ƙwayar cuta, rikicewar ƙwayar cystic fibrosis, legionellosis, empyema da ƙurawar huhu.
- Cututtuka na Otolaryngological: sinusitis, otitis media, mastoiditis, pharyngitis, agranulocytic tonsillitis.
- Cutar mahaifa: pyelonephritis, cystitis, tubulointerstitial nephritis, oophoritis, endometritis, salpingitis, orchitis, epididymitis, prostatitis, balanoposthitis, gonorrhea.
- Peritonitis da sauran raunuka na ciki-na ciki. Anan, ana amfani da maganin rigakafi azaman wani ɓangaren hadadden magani.
- Cholecystitis, wanda ya hada da ba'a bayyana ba, cholangitis, empyema na ƙwayar ƙwayar cuta.
- Cututtukan narkewar abinci, gami da shigellosis, zazzabi, zazzabin ƙwayoyin cuta.
- Kamuwa da cuta daga cikin mahaɗan ciki da ƙananan yadudduka: ƙurji, furucin, furunlera, raunuka, raunuka, ƙonewa tare da alamun kamuwa da cuta na sakandare.
- Kwayar cuta ta mahaifa: myositis, bursitis, tendosynovitis, osteomyelitis, cututtukan cututtukan fata.
- Sepsis, bacteremia, cututtukan huhu, cututtukan cikin marasa lafiya da ke da rauni mai rauni (tare da magungunan hana ƙwayoyin cuta).
- Yin rigakafin kamuwa da cuta, gami da Neisseria meningitidis da kuma ƙwayoyin cuta na Bacillus anthracis.
Ba za a iya amfani da Tsiprolet 500 ba yayin ɗaukar yaro.
Contraindications
Bai kamata a yi amfani da maganin ba idan abun da ke ciki ya kasance mai haƙuri ko tare da tarihin rashin hankali ga magungunan fluoroquinolone. Sauran cututtukan contraindications sun haɗa da:
- enterocolitis na pseudomembranous;
- shan tizanidine saboda hadarin matsanancin rashin ƙarfi;
- ƙuruciya da balaga (an ba shi damar amfani da Ciprolet ga yara daga 5 shekara don murƙushe ayyukan Pseudomonas aeruginosa a gaban ƙwayar cystic fibrosis, kazalika don kawar da hana kamuwa da cuta tare da ƙwayar cuta ta Bacillus);
- haihuwar ɗa;
- lactation.
Tare da kulawa
Ana buƙatar kulawa ta musamman a cikin tsofaffi marasa lafiya, marasa lafiya tare da raunin hepatic-renal, insubiciency na cerebrovascular, a gaban cututtukan fata.
Yadda ake ɗaukar Ziprolet 500
Ana amfani da maganin na musamman kamar yadda likita ya umarce shi. Ana iya shan kwayoyin cutar ba tare da la'akari da abincin ba. Idan kun sha a kan komai a ciki, to za su yi sauri. An haɗiye su duka an bushe da ruwa. Yin amfani da wannan magani a lokaci daya yana tare dashi tare da ruwan 'ya'yan itace wanda aka wadatar da ma'adinai tare da samfuran kiwo (gami da yogurt a cikin capsules a matsayin mai hanawa).
Ana amfani da maganin Ciprolet na musamman kamar yadda likita ya umurce shi.
Ana yin allurai dabam-dabam gwargwadon abubuwan da ke nuni, da raunin ƙwayar cuta, da tsananin rauni da kuma ciwon rauni. Manya suna ɗaukar allunan MG 500 sau biyu a rana. Idan ya cancanta, ana ƙaruwa da kashi ɗaya. Yawan maganin yau da kullun kada ya wuce 1.5 g. Idan an buƙata, ana gudanar da maganin ne tare da canzawa zuwa maganin kulawa ta baka. Abubuwan da ke cikin jijiyar ciki ba su yi ba.
Sakamakon farko da tabbatarwa ana bada shawarar ne ga marassa lafiyar da ke fama da rauni aiki. Tare da sharewar creatinine da ke ƙasa 30 ml / min, tazara tsakanin allurai yana ƙaruwa zuwa awanni 24. Ga yara da matasa, an wajabta maganin rigakafi lokacin da ya zama tilas, saboda zai iya haifar da arthropathy. Ana lasafta allurai gwargwadon nauyin yaron.
Wasu cututtukan cututtukan da ke haifar da kumburi (kamuwa da abubuwa na kasusuwa-gishirin, gabobin ciki, da ƙashin ƙugu) suna buƙatar amfani da wasu magungunan ƙwayoyin cuta a layi daya. Matsakaicin tsawon magani shine makonni 1-2. Wani lokacin aikin warkewa yana buɗewa tsawon watanni.
Shin zai yiwu a sha maganin don ciwon sukari
Babu contraindications don amfanin Ciprolet ta masu ciwon sukari. Ikon ƙwayar zai haifar da hawa da sauka a matakan sukari a cikin shugabanci ɗaya ko wani ya kamata a la'akari.
Lokacin ɗaukar Ciprolet, hanawar aiki na aikin hematopoietic da kuma canji a cikin ƙwayoyin salula na jini mai yiwuwa ne.
Side effects
An yarda da maganin rigakafi da kyau, amma a wasu halaye zai iya haifar da adadin masu illa.
Gastrointestinal fili
Marasa lafiya suna koka da tashin zuciya, amai, haɓakar gudawa, zafin ciki, rashin jin daɗi. Da wuya, candidiasis na mucosa na bakin, laryngeal edema, kumburi, kumburi hanta (ciki har da gazawar hanta), hepatitis, necrosis nama, cholestasis, ƙara yawan aiki na enzymes hanta, pseudomembranous enterocolitis.
Hematopoietic gabobin
Haramcin aikin hematopoietic da kuma canji a cikin tsarin salula na jini, gami da leukocytosis da pancytopenia, na iya yiwuwa.
Tsarin juyayi na tsakiya
Dizziness, migraines, gajiya mai tsanani, asthenia, tashin hankali, rashin bacci, damuwa, psychotic halayen, matsaloli tare da daidaituwa na motsi, tashin hankali, bayyanar m, paresthesia, neuropathy, dandano da ƙanshi, ringing a cikin kunnuwa, reversable ji rashi, diplopia da sauran mahaukaci na gani.
Daga tsarin urinary
Shan maganin rigakafi na iya haifar da rudani a cikin aikin kodan, bayyanar jini a cikin fitsari, haɓakar ƙwayar cuta, da haɓakawa cikin haɗakar creatinine.
Lokacin ɗaukar Cyprolet 500, farji, migraine, da gajiya na iya faruwa.
Daga tsarin zuciya
Zai yiwu tachycardia, hauhawar jini, filasha mai zafi, launin ja, fuska, tsawaita tazara ta QT a cikin zuciya, pirouette arrhythmia, vasculitis.
Cutar Al'aura
Mafi sau da yawa, halayen fata suna faruwa: rashes, busa, hyperemia, itching, urticaria. Wani lokaci fitsari ya bayyana. Hoto mai ɗaukar hoto, mummunan erythema, necrolysis na integuments, bronchospasm, gigicewar anaphylactic, zazzabi, jin zafi a cikin tsokoki da gidajen abinci mai yiwuwa.
Umarni na musamman
A cikin mummunan rauni, cututtukan streptococcal, cututtukan da ke haifar da cututtukan ƙwayar cuta na anaerobic, magani tare da Tsiprolet ya kamata a haɗe tare da sauran wakilai na rigakafi.
Zazzabin cizon sauro sakamakon shan ƙwayoyin cuta ba zai iya kawar da shi ba tare da taimakon magungunan da ke hana aikin motsi na hanji ba.
Ciprofloxacin na iya haifar da katsewar jijiyon, sanyin jiji, da haɓakawar superinfection.
Amfani da barasa
Yayin shan magungunan rigakafi, abubuwan sha giya da magunguna masu ɗauke da giya kada su sha.
Tasiri kan ikon sarrafa abubuwan inji
Abunda ya faru daga tsarin mai juyayi da gabobin jijiya na iya yiwuwa, saboda haka, lokacin tuki mota da sarrafa abubuwa masu haɗari, dole ne a kula.
Yi amfani da lokacin daukar ciki da lactation
Mata masu juna biyu da uwaye masu shayarwa ba tare da sunyen jariri ba daga nono, shan maganin yana dauke da cutar.
Adana kalmomin Cyprolet ga yara 500
Iyakar shekarun shine shekaru 18. Za'a iya amfani da miyagun ƙwayoyi a lokacin ƙuruciya don magani da rigakafin cutar huhu ko don magance Pseudomonas aeruginosa a cikin marasa lafiya tare da ƙwayar cystic fibrosis. Amma a cikin waɗannan halayen, ya fi dacewa don amfani da sashi na 250 MG, maimakon 500 MG.
Yawan damuwa
Bayyanar cututtuka na yawan abin sama da ya kamata:
- ciwon kai
- vertigo;
- katsewa
- rawar jiki
- jin zafi a ciki;
- hallucinations;
- na koda hepatic rashi;
- yawan kuka;
- jini a cikin fitsari.
Wajibi ne a wofin ciki kuma a gudanar da aikin tiyata. Yana da mahimmanci a kula da aikin kodan tare da bin tsarin ingantaccen sha. Rashin daidaituwa ba shi da tasiri.
Mata masu juna biyu da uwaye masu shayarwa ba tare da yayen da ke shayar da jariri daga nono ba, shan ciprolet din yana daukar ciki.
Yin hulɗa tare da wasu kwayoyi
Ciprolet yana haɓaka abun ciki na Theophylline a cikin jini na jini, yana rage jinkirin kawar da wakilai na maganin antidiabetic, xanthines da NSAIDs (ban da Aspirin), haɓaka nephrotoxicity na Cyclosporin da kuma tasiri na Warfarin. Shirye-shiryen magnesium, baƙin ƙarfe, aluminum da zinc yana rage jinkirin ciprofloxacin, don haka kuna buƙatar amfani da su tazara na 4.
Magungunan da ake tambaya sun dace da sauran magungunan kashe ƙwayoyin cuta:
- Metronidazole;
- Vancomycin;
- ceflosporins;
- penicillins;
- aminoglycosides;
- karafarini.
Eazantawarta yana raguwa a gaban Probenecid, kuma a haɗe tare da NSAIDs, haɗarin bayyanar bayyanar yana ƙaruwa.
Analogs na Tsiprolet 500
Tsarin analogues na miyagun ƙwayoyi:
- Ciprofloxacin.
- Kirkira.
- Afenoksim.
- Tsiprosan.
- Tsiproksin.
- Karatu.
- Ciprinol.
- Quintor et al.
Hadin magunguna tare da wata kwayoyi a cikin abun da ke ciki, alal misali, Ciprolet A tare da tinidazole, za'a iya tsara shi.
Magunguna kan bar sharuɗan
An sake shi ta hanyar takardar sayan magani.
Farashi
Kudin allunan 500 MG shine daga 54 rubles. kowace kunshin (10 inji mai kwakwalwa.).
Yanayin ajiya na Tsiprolet 500
An adana maganin a cikin ɓoye a yanayin zafi har zuwa + 25 ° C a wuri mara amfani ga yara.
Ranar karewa
Shekaru 3
An adana maganin a cikin ɓoye a yanayin zafi har zuwa + 25 ° C a wuri mara amfani ga yara.
Nunawa game da Tsiprolet 500
Magungunan yana karɓar dubun dubbai masu kyau game da likitoci da marasa lafiya.
Likitoci
Kartsin N.S., Urologist, Tver
Wannan ƙwayoyin rigakafin ƙwayar cuta ta fluoroquinolone yana da tasiri musamman ga mummunan kumburi na ƙwayar ƙwayar cuta. A bu mai kyau pre-shuka.
Turimova O. N., therapist, Krasnodar
A miyagun ƙwayoyi yana da m wide bakan aikin. Yana aiki da sauri. Abubuwan sakamako suna da wuya.
Marasa lafiya
Lyudmila, shekara 41, garin Kerch
Na sha kwayoyin hana daukar ciki don angina. A kwanakin farko yana da wahalar hadiye. Amma sakamakon ya gamsu: ciwon makogwaro kuma babu sakamako masu illa.
Anatoly, 37 years old, Ryazan
Ina shan wannan maganin tare da fashewar cututtukan fata na kwanaki 5, kodayake alamun sun ɓace tuni don kwanaki 3-4. Da zarar likita ya ba da wani maganin rigakafi, saboda abin da zawo ya fara. Don haka kawai za a bi da ni tare da Cyprolet. Jikinsa yaji dadin abunda yafi kyau.
