Protafan NM Penfill wakili ne na warkewa wanda aikinsa yana da nasaba da kula da masu ciwon sukari. Magungunan, lokacin da aka yi amfani da shi daidai, yana ba ku damar bin matakin da ake buƙata na glucose a cikin jini, ba tare da cutar da lafiyar mai haƙuri ba.
Sunan kasa da kasa mai zaman kansa
Jinin ɗan adam.
ATX
A.10.A.C - insulins da kwatankwacinsu tare da matsakaicin lokacin aiki.
Saki siffofin da abun da ke ciki
Dakatarwa don subcutaneous management na 100 IU ml ana samun su ta hanyar: kwalba (10 ml), kabad (3 ml).
Tsarin 1 ml na miyagun ƙwayoyi ya ƙunshi:
- Abubuwan da ke aiki: insulin-isophan 100 IU (3.5 mg).
- Abubuwa masu taimako: glycerol (16 mg), zinc chloride (33 μg), phenol (0.65 mg), sinadarin hydrogen phosphate dihydrate (2.4 mg), protamine sulfate (0.35 mg), sodium hydroxide (0.4 mg) ), metacresol (1.5 MG), ruwa don yin allura (1 ml).
Dakatarwa don subcutaneous management na 100 IU ml ana samun su ta hanyar: kwalba (10 ml), kabad (3 ml).
Aikin magunguna
Yana nufin jami'in hypoglycemic yana da matsakaicin tsawon lokacin aiki. An samar dashi ta hanyar fasahar DNA ta sake amfani da fasaha ta amfani da Saccharomyces cerevisiae. Yana hulɗa tare da masu karɓar membrane, samar da hadaddun insulin-receptor wanda ke inganta haɓakar enzymes da ke rayuwa (hexokinases, glycogen synthetases).
Magungunan yana motsa jigilar sunadarai ta hanyar sel. Sakamakon haka, haɓaka glucose yana inganta, ana inganta lipo- da glycogenesis, kuma haɓakar glucose ta hanta yana raguwa. Bugu da ƙari, an kunna aikin furotin.
Pharmacokinetics
Ingantaccen ƙwayar da saurin tsabarta yana ƙaddara ta sashi, wurin allurar, hanyar allura (subcutaneous, intramuscular), abun cikin insulin a cikin magani. Matsakaicin abun ciki na abubuwanda aka sanya cikin jini ana kai shi ne bayan sa'o'i 3 zuwa 16 bayan allura.
Alamu don amfani
Ciwon sukari
Protafan NM Penfill wakili ne na warkewa wanda aikinsa yana da nasaba da kula da masu ciwon sukari.
Contraindications
Tare da hypersensitivity ga insulin na mutum ko abubuwan da ke sanya magungunan, an haramta hypoglycemia.
Tare da kulawa
Hankali wajabta shi idan ba kiyaye farfahanin abincin da aka saba ko yawan aiki na jiki, kamar hypoglycemia na iya faruwa. Hakanan yin taka tsantsa shima ya zama dole yayin juyawa daga wani nau'in insulin zuwa wani.
Yadda ake ɗaukar Protafan NM Penfill?
Yi allurar ciki ko subcutaneous allura. An zaɓi sashi yana la'akari da ƙayyadaddu da halayen cutar. Yawan halatta na insulin ya bambanta tsakanin 0.3-1 IU / kg / rana.
A saka allurar ta yin amfani da pen. Mutanen da ke da juriya na insulin suna ƙaruwa da buƙatar insulin (a lokacin haɓaka jima'i, nauyin jikin mutum ya wuce kima), don haka an umurce su da matsakaicin adadin.
Don rage haɗarin lipodystrophy, ya wajaba don maye gurbin wurin gudanar da maganin. Dakatarwa, bisa ga umarnin, an hana shi sosai shiga ciki.
Tare da ciwon sukari
Ana amfani da Protafan ga kowane nau'in ciwon sukari. Aikin warkewa yana farawa ne da nau'in ciwon suga guda 1. An tsara nau'in magani na 2 idan babu wani sakamako daga abubuwan da suka samo asali na sulfonylurea, a lokacin daukar ciki, lokacin da bayan tiyata, tare da rakiyar cututtukan da ke da tasirin gaske game da cutar sankara.
Sakamakon sakamako na Protafan NI Penfill
Abubuwan da ke faruwa mara kyau da aka lura a cikin marasa lafiya a lokacin warkewa hanya suna faruwa ne ta hanyar jaraba kuma suna da alaƙa da aikin magunguna na miyagun ƙwayoyi. Daga cikin mawuyacin halayen da ake fama da su, ana lura da cutar hypoglycemia. Yana bayyana sakamakon rashin bin ka'idojin insulin.
A cikin tsananin rashin ƙarfi, asarar hankali, rashi, aikin kwakwalwa, da kuma wani lokacin mutuwa, mai yiwuwa ne. A wasu halaye, akwai take hakkin metabolism na metabolism.
A wani ɓangare na rigakafi na iya yiwuwa: kurji, urticaria, haɓaka mai ɗaci, ƙaiƙayi, ƙarancin numfashi, tashin zuciya, rugujewar hawan jini, raunin hauka.
A wani ɓangare na rigakafi, mummunan sakamako mai yiwuwa ne: kurji, urticaria, itching.
Tsarin juyayi shima yana cikin haɗari. A cikin lokuta masu wuya, neuropathy na baya yana faruwa.
Umarni na musamman
Selectedaran da aka zaɓa ba bisa ƙa'ida ba ko katsewa cikin jijiyoyin jiki suna haifar da cutar hauka. Alamar farko fara bayyana ne a cikin 'yan awanni ko kwanaki. Idan ba a ba da taimako akan lokaci ba, hadarin kamuwa da cutar ketoacidosis, wanda ke cutar da rayuwar mutum yana ƙaruwa.
Tare da cututtukan concomitant pathologies waɗanda ke nuna zazzabi ko kamuwa da cuta, buƙatar insulin a cikin marasa lafiya yana ƙaruwa. Idan ya cancanta, canza sashi za'a iya gyara shi a lokacin allurar farko ko tare da ƙarin magani.
Yi amfani da tsufa
Marasa lafiya har zuwa shekara 65 ba su da ƙuntatawa kan shan maganin. Bayan sun kai wannan zamani, marassa lafiya yakamata su kasance karkashin kulawar likita kuma suyi la’akari da abubuwan da suka danganci su.
Adana Protafan NM Penfill ga yara
Za'a iya amfani dashi ga yara 'yan ƙasa da shekara 18. An kafa sashi ne daban-daban kan binciken. Mafi sau da yawa ana amfani dashi a cikin nau'in diluted.
Yi amfani da lokacin daukar ciki da lactation
Anyi amfani dashi yayin daukar ciki, as bai ƙetare mahaifa ba. Idan ba a kula da cutar sankara ba a lokacin lokacin haihuwa, hadarin zuwa tayi yana ƙaruwa.
Rikicewar ƙwayar cuta yana faruwa tare da hanyar da ba a zaɓa ba ta hanyar magani, wanda ke kara haɗarin lahani ga yaro kuma ya yi masa barazanar mutuwar ciki. A cikin watanni na farko, buƙatar insulin ya ragu, kuma a cikin 2 da 3 yana ƙaruwa. Bayan bayarwa, buƙatar insulin ya zama iri ɗaya.
Magungunan ba shi da haɗari lokacin shayarwa. A wasu yanayi, ana buƙatar yin gyare-gyare ga tsarin allura ko abinci.
Doaukar hoto na Protafan NI Penfill
Ba a gano allurai da suke haifar da wucewar jini ba. Ga kowane mai haƙuri, yin la'akari da ƙayyadaddun hanyoyin cutar, akwai babban adadin, wanda ke haifar da bayyanar cututtukan hyperglycemia. Tare da yanayi mai laushi na hypoglycemia, mai haƙuri zai iya jure shi da kansa ta hanyar cin abinci mai daɗi da abinci mai ɗauke da ƙwayoyin carbohydrates mai yawa. Ba shi da rauni a koyaushe a kan kayan lefe na hannu, kukis, ruwan 'ya'yan itace ko kuma sukari kawai.
A cikin siffofin masu tsanani (rashin sani), maganin glucose (40%) an allura a cikin jijiya, 0.5-1 mg na glucagon karkashin fata ko tsoka. Lokacin da aka kawo mutum hankali, don guje wa hadarin sake dawowa, sukan ba da abinci mai-carb.
Yin hulɗa tare da wasu kwayoyi
Magungunan hypoglycemic suna ƙaruwa sakamakon insulin. Masu hana monoamine oxidase, carbonhy anhydrase da angiotensin-canza enzyme, Bromocriptine, Pyridoxine, Fenfluramine, Theophylline, magungunan ethanol, Cyclophosphamide yana haɓaka tasiri insulin.
Yin amfani da maganin hana haihuwa, kwayoyin hodar iblis, Heparin, Phenytoin, Clonidine, Diazoxide, morphine da nicotine, glucocorticosteroids suna haifar da tasirin rauni na miyagun ƙwayoyi. Reserpine da salicylates, Lanreotide da Octreotide sun sami damar haɓakawa da rage tasirin kayan aikin.
Beta-blockers suna ɓoye alamun farko na hypoglycemia kuma suna wahalar da ƙarshen kawar dashi.
Amfani da barasa
Alkahol yana haɓakawa kuma yana ƙaruwa da tasirin maganin.
Analogs
Magungunan maye gurbi waɗanda ke da irin wannan sakamako: Gaggawar gaggawa ta protamine-insulin, Gensulin N, Humulin NPH, Insuman Bazag GT.
Magunguna kan bar sharuɗan
Da takardar sayan magani.
Zan iya saya ba tare da takardar sayan magani ba?
A'a.
Farashi
Kudin kwalban 10 ml shine 400-500 rubles, katun katako shine 800-900 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Dole ne a adana magungunan a cikin sanyi da wuri mai duhu a zazzabi na + 2 ... + 8 ° C (ana iya sanya shi a cikin firiji, amma ba firiji). Ba batun daskarewa bane. Dole ne a ajiye katun a cikin kayan aikin domin kare ta daga hasken rana.
Ana ajiye akwati mai buɗewa a cikin 30 ° C bai wuce kwanaki 7 ba. Kada a ajiye a firiji. Hana yara damar shiga.
Ranar karewa
Shekaru 2.5. Bayan an bada shawarar zubar dashi.
Mai masana'anta
NOVO NORDISK, A / S, Denmark
Nasiha
Svetlana, dan shekara 32, Nizhny Novgorod: "A lokacin daukar ciki na yi amfani da Levemir, amma cutar rashin jini a jiki ta bayyana koyaushe. Likitan da ke halartar ya ba da shawarar canzawa zuwa allurar Protafan NM Penfill. Yankin ya daidaita, ba a lura da cutarwa ba a duk cikin ciki da bayanta."
Konstantin, ɗan shekara 47, Voronezh: "Na kamu da ciwon sukari na tsawon shekaru 10. Ban iya zaɓar maganin da ya dace don riƙe glucose na jini ba koyaushe. Na sayi allurar Protafan NM Penfill watanni shida da suka gabata kuma na yi farin ciki da sakamakon. matsaloli da rikice-rikice da suka bayyana a baya ba sa sake jin kansu. Farashi mai araha ne. "
Valeria, dan shekara 25, St. Petersburg: “Na kamu da ciwon sukari tun ina ƙuruciya. Na gwada magunguna sama da 7, kuma babu ɗayansu da ke cike da ƙoshin magunguna na ƙarshe da na saya akan umarnin likita na dakatar da Protafan NM Penfill. Har zuwa ƙarshe, na yi shakkarsa Ban yi fatan gaske cewa yanayin zai canza ba. Amma na lura cewa bayyanar cututtukan jini ba ta da wata damuwa, lafiyar ta gaba ɗaya ta al'ada ce. Na saya a cikin kwalabe. Magungunan sun dace da amfani kuma ba su da tsada. "
