Ultrashort insulin Glulizin - halaye da fasali na aikace-aikace

A cikin nau'in 1 na ciwon sukari, mai haƙuri zai iya amfani da insulin-sauri (mai sauri), gajere, matsakaici, tsawanta da pre-hade insulin.

Wanne zaka iya rubuto don ingantaccen tsarin kulawa ya dogara da halaye na jiki. Idan ana buƙatar insulin matsananci-gajere, ana amfani da Glulisin.

A takaice game da insulin Glulizin

Kwayar insulin

Insulin Glulisine kwatankwacin insulin ne na ɗan adam, wanda yayi kama da ƙa'idar wannan hormone. Amma ta yanayin, yana aiki da sauri kuma yana da gajarta sakamako.

An gabatar da Glulisin azaman mafita don gudanar da aikin ƙarƙashin ƙasa. Yana kama da daskararren ruwa ba tare da ƙazanta ba.

Sunayen kasuwanci don magunguna tare da kasancewarsa: Apidra, Epidera, Apidra Solostar. Babban burin maganin shine daidaita tsarin metabolism.

Dangane da kwarewar amfani, za a iya bambanta waɗannan ab advantagesbuwan amfãni da rashin amfani:

• yana aiki da sauri fiye da ƙwayar mutum (+);
• yana biyan bukatun abinci cikin insulin (+);
• yiwuwar rashin tabbas game da tasirin kwayoyi akan matakan glucose (-);
• babban iko - rukunin yana rage sukari fiye da sauran insulins (+).

Pharmacology da pharmacokinetics

Bayan subcutaneous አስተዳደር, akwai raguwa a cikin glucose saboda taɓarɓare amfani dashi a cikin kyallen takarda da kuma dakatar da waɗannan hanyoyin a cikin hanta. Wannan aikin yana farawa minti 10 bayan allura.

Tare da gabatarwar Glulisin da insulin na yau da kullun 'yan mintoci kaɗan kafin cin abinci, tsohon yana sarrafa mafi kyawun kulawar glycemic bayan cin abinci. A bioavailability na abu ne kusan 70%.

Sadarwa tare da sunadaran plasma sakaci ne. Yana da sauri kadan fiye da sirinjin ɗan adam na yau da kullun. Rabin rayuwar mintuna 13.5.

Umarnin don amfani

Ana gudanar da miyagun ƙwayoyi nan da nan kafin abinci (na mintoci 10-15) ko kuma nan da nan bayan cin abinci, la'akari da tsarin kulawa na gaba ɗaya tare da sauran insulins (ta hanyar aiki ko ta asali). Hanyar gudanarwa: subcutaneously a cinya, kafada. Don guje wa raunin da ya faru, an sanya wurin da allura ta yi sanyi. Ana amfani da maganin a wurare daban-daban, amma a cikin yanki ɗaya.

An haɗu da glulisin tare da abubuwan insulins da masu zuwa:

• tare da analog na hormone na basal;
• tare da matsakaici;
• tare da dogon;
• tare da tableted hypoglycemic kwayoyi.

Darfafawar glycemia tare da ƙari na insulin Glulizin zuwa far tare da insulin basal

Idan mafita ana nufin gudanar dashi ta amfani da almarar sirinji, ana yin allura gwargwadon umarnin wannan aikin. An zabi sashi na magungunan daban daban, la'akari da yanayin mai haƙuri da matakin diyya.

Kafin amfani da Glulizin, wanda aka cika a cikin kicin, ana gudanar da bincike - maganin laka tare da inclusions bai dace da amfani ba.

Umarni na bidiyo akan amfani da alkairin sirinji:

Alamu, sakamako masu illa, yawan shan ruwa

An wajabta magani a cikin waɗannan abubuwan:

• Nau'in cuta guda 1;
• Nau'in cuta guda 2;
• Ciwon sukari a cikin yara daga shekaru 6.

Contraindications zuwa alƙawarin miyagun ƙwayoyi sune kamar haka:

• hypoglycemia;
• rashin kwanciyar hankali ga glulisin;
• rashin hankali ga abubuwan taimako na miyagun ƙwayoyi.

A yayin aiwatar da magani tare da miyagun ƙwayoyi, mummunan halayen na iya faruwa.

Mitar haɗari a cikin lambobi, inda 4 ya zama ruwan dare gama gari, 3 sau da yawa, 2 ba wuya, 1 yana da wuya sosai:

A yayin yawan zubar da jini, ana lura da cutar rashin ƙarfi da damuwa dabam dabam. Zai iya faruwa kusan nan da nan ko kuma a hankali a hankali.

Dangane da tsananin aikin insulin, tsawon lokacin da tsananin cutar, alamu na iya haifar da karin haske. Yakamata mai haƙuri yayi la’akari da wannan bayanin domin hana yanayin cikin ƙimar lokaci. Don yin wannan, dole ne ku sami sukari (alewa, cakulan, ƙwal sukari mai tsabta) tare da ku.

Tare da matsakaiciyar matsakaiciyar matsakaici da matsakaici, ana ɗaukar samfuran sukari da ke ɗauke da sukari. A cikin yanayi mai tsanani, wanda ke tattare da asarar hankali, za a buƙaci allura.

Dakatar da hypoglycemia yana faruwa ne tare da taimakon glucagon (s / c ko i / m), maganin glucose (i / v). A cikin kwanaki 3, ana kula da yanayin haƙuri. Don hana haɓakar haɓakar hypoglycemia, wajibi ne don ɗaukar carbohydrates bayan ɗan lokaci.

Hulɗa da ƙwayoyi

A farkon farawa tare da insulin ultrashort, hulɗarta da sauran magunguna ana la'akari da ita.

Yawancin kwayoyi na iya shafan metabolism, haɓaka ko rage tasirin insulin ultrashort. Kafin jiyya, ya kamata a sanar da mara lafiyar don hana rigakafin sakamako.

Magunguna masu zuwa suna inganta tasirin Glulisin: Fluoxetine, wakilin hypoglycemic a cikin allunan, musamman, sulfonylureas, sulfonamides, salicylates, fibrates, ACE inhibitors, Disopyramide, MAO inhibitors, Pentoxifylline, Propoxifen.

Magunguna masu zuwa suna rage tasirin insulin farfajiya: magungunan rigakafin ƙwayar cuta na yau da kullun, abubuwan juyayi, rigakafi na baka, hormones thyroid, glucagon, hormones na mata, thiodiphenylamine, somatropin, diuretics, glucocorticosteroid kwayoyi (GCS), protein inhibitors,

Ana magana da Pentamidine, beta-blockers, clonidine zuwa magungunan da ba a iya tsammani ba zasu iya tasiri da ƙarfin tasirin Glulisin da matakin glucose (raguwa da haɓaka). Barasa yana da abubuwa iri ɗaya.

Ana lura da taka tsantsan yayin kulawa da Pioglitazone ga marasa lafiya da cututtukan zuciya. Lokacin da aka haɗu, an bayar da rahoton maganganun ci gaban bugun zuciya a cikin marasa lafiya tare da tsinkayar wannan cutar.

Idan magani tare da Pioglitazone ba za a iya soke shi ba, wajibi ne a kula da yanayin. Idan an bayyanar da duk wata alama ta zuciya (karin nauyi, kumburi), sai an soke amfani da maganin.

Umarni na musamman

Yakamata mai haƙuri yayi la'akari da waɗannan:

1. Tare da dysfunction koda ko wani abin ƙeta a cikin aikinsu, buƙatar insulin na iya raguwa.
2. Tare da lalata hanta, buƙatun kuma yana raguwa.
3. Saboda ƙarancin bayanai, ba a ba da magani ga yara 'yan ƙasa da shekara shida.
4. Yi amfani da taka tsantsan a cikin mata masu juna biyu tare da saka idanu akai-akai na alamu.
5. Yayin lactation, ana buƙatar sashi da daidaitawar abinci.
6. Lokacin canzawa zuwa Glulisin daga wani ƙwayar cuta saboda yawan shakatawa, ya kamata a yi gwajin alerji don ware ƙaiƙayi.

Daidaitawar sashi

Ana aiwatar da gyaran fuska yayin juyawa daga wani nau'in allurar ƙwayar ciki. Lokacin canzawa daga insulin dabbobi zuwa Glulisin, ana daidaita sashin sau da yawa a cikin shugabanci na rage ƙarshen. Buƙatar magungunan na iya canzawa tare da yawan damuwa / damuwa na damuwa, a lokacin cutar cuta.

An tsara wannan tsarin ta hanyar taimakon magungunan ƙwayoyin cuta na ƙwaƙwalwar ƙwayar cuta. Idan ka canza kowane bangare na makircin, zaku buƙaci daidaita sashin Glulisin.

A lokuta da yawa na cututtukan hyperglycemia / hypoglycemia, waɗannan abubuwan da suka dogara da kashi-kashi ana fara tantance su kafin canza sashi na maganin:

• dabara da wurin sarrafa magunguna;
• tsananin riko da tsarin kulawa;
• amfani da wasu magunguna;
• jihar-psycho rai.

Informationarin Bayani

Kyau - shekaru 2

Rayuwar shelf bayan budewa - watan

Adana - a t daga +2 zuwa + 8ºC. Kar a daskare!

Hutu ne ta hanyar sayan magani.

Glulisin kwatankwacin insulin mutum ne:

• Insuman Rapid;
• Humulin;
• Humodar;
• Gensulin P;
• Vosulin P;
• Aiki

Glulisin shine hormone na ultrashort don daidaita tsarin metabolism. An tsara shi tare da sauran insulins, yin la'akari da tsarin da aka zaɓa na gaba ɗaya. Kafin amfani, yana da muhimmanci a bincika takamaiman umarnin da hulɗa tare da wasu magunguna.