Sabbin magunguna don maganin cututtukan type 2

Nau'in ciwon sukari na 2 (T2DM) wata cuta ce wacce ake samun raguwar halayyar sel zuwa insulin, a sanadiyyar wanda glucose ya daina shiga cikinsu ya zauna cikin jini. Idan ba a dauki matakan ba, to nau'in ciwon sukari na 1 ya fara, wanda ke nuna halakar lalata ƙwayoyin beta da ke haifar da insulin. Kuma bayan haka dole ne ku dauki shirye-shiryen insulin don rayuwa, wanda zai tallafawa jiki a cikin yanayin al'ada.

A saboda wannan dalili, ana bada shawarar yin magani don farawa daga ranar farko ta haɓakar T2DM. Don yin wannan, ɗauki magunguna na musamman waɗanda suke ƙara haɓaka hankalin ƙwayoyin zuwa insulin. Yanzu zamuyi la'akari da jerin allunan sabon ƙarni na mellitus na sukari na 2, wanda aka fi amfani dashi azaman maganin ƙwayar cuta ga wannan cuta. Amma! An bayar dashi don dalilai na bayanai kawai. Ba za ku iya shan kwayoyi ba tare da takardar sayan likita!

Tsarin magunguna

Tare da haɓaka nau'in ciwon sukari na 2, marasa lafiya ba a rubuta musu magani kai tsaye. Don masu farawa, ingantaccen tsarin abinci da matsakaici na jiki sun isa don samar da iko akan sukari na jini. Koyaya, irin waɗannan abubuwan ba koyaushe suna ba da sakamako mai kyau ba. Kuma idan ba a lura dasu tsakanin watanni 2-3 ba, nemi taimakon magunguna.

Duk magunguna don maganin ciwon sukari sun kasu zuwa kungiyoyi da yawa:

• asirin, inganta haɓakar insulin ta hanyar ƙwayoyin beta na pancreas, sun kasu kashi biyu na sulfonylureas da megoitinides;
• masu hankali, wanda ke kara azama da jijiyoyin jikin mutum zuwa insulin, suna da rukunoni biyu - biguanides da thiazolidinediones;
• alpha glucosidase inhibitors wanda ke haɓaka tsarin rushewa, ɗaukar ciki da fitowar carbohydrates daga jiki;
• incretins, waxanda suke da sababbin sababbin magunguna waɗanda ke da tasirin gaske a jiki.

Sulfonylureas

An yi amfani da magunguna na wannan rukunin magungunan a matsayin maganin warkewa don kamuwa da cutar sankara fiye da shekaru 50. A cikin abubuwan haɗin su sun ƙunshi abubuwa waɗanda ke tabbatar da daidaituwa na sukari na jini sakamakon kunna ƙwayoyin beta waɗanda ke da hannu a cikin samar da insulin. A sakamakon haka, maida hankali a cikin jini yana ƙaruwa kuma ƙwaƙwalwar sel kai tsaye zuwa glucose yana ƙaruwa.

Bugu da kari, abubuwanda ke haifar da sinadarin na sulfonylurea suna samar da sabuntawar sel din yara kuma suna kara sautin ganuwar jijiyoyin jiki, ta haka hakan zai iya haifar da hadarin ire-iren yanayin cutar ta T2DM.

Jerin abubuwan samo asali na sulfonylurea

Koyaya, waɗannan kwayoyi suna da ɗan gajeren sakamako na warkarwa. Amfani da na dogon lokaci a cikin nau'in 2 na ciwon sukari a hankali yana yanke ƙwayoyin cututtukan cututtukan cututtukan hanji, ta hakan ne suke haifar da ci gaban ciwon sukari na 1. Bugu da kari, yawanci suna haifar da halayen rashin lafiyan mutum, rikicewar ƙwayar jijiyoyin ciki da cutar mahaifa.

Babban contraindications ga shan kwayoyi na rukunin abubuwan samo asali na sulfonylurea sune halaye da cututtuka masu zuwa:

• ciki
• lactation
• yara ‘yan kasa da shekara 12;
• cututtukan fitsari.

Daga cikin abubuwan da suka samo asali na sulfonylurea, wadanda suka shahara sune:

• Glycidone. Ana amfani dashi galibi don magance cututtukan type 2 na tsofaffi. Yana da ƙananan adadin contraindications kuma da wuya ya tsokani bayyanar sakamako masu illa. Wani mahimmin fasalin wannan magani shine cewa ana iya ɗauka har a gaban cuta irin su rashin aikin koda.
• Maninil. Wannan magani shine ɗayan mafi kyau, saboda yana da ikon adana sukari na jini a cikin iyakoki na yau da kullun na kusan kwana ɗaya. Akwai shi cikin magunguna daban-daban kuma ana iya amfani dashi duka don maganin T1DM da T2DM.
• Mai ciwon sukari. Yana haɓaka ƙwayar insulin kuma yana ƙarfafa tsarin jijiyoyin jini. Ana amfani dashi a cikin ciwon sukari azaman maganin alaƙa.
• Amaril. Magungunan sau da yawa ana umurce su da ciwon sukari na nau'in farko da na biyu, musamman ga tsoffi. Pe pe is Its Its Its is

Amaril

Wadannan magungunan don ciwon sukari na 2 sune suka fi yawa a cikin aikin likita, saboda da wuya suna tsokanar da karuwar jiki da kuma kiba, wanda hakan ke kara tsananta cutar.

Meglitinides

Magunguna daga wannan rukunin magunguna suna ba da haɓakar haɓakar insulin. Komawa ga sabon ƙarni na magunguna don ciwon sukari, tasirin sa wanda ya dogara da narkar da glucose a cikin jini. Duk yadda yake, da yawan aiki zai zama kwayar insulin.

Wannan rukunin magungunan sun hada da Novonorm da Starlix. Halinsu shine cewa suna aiki da sauri kuma suna hana faruwar rikicin haɓaka tare da haɓaka sukari na jini. Koyaya, tasirin su ya ci gaba na ɗan gajeren lokaci.

Wadannan kwayoyi don nau'in ciwon sukari na 2 na sabon zamani suna da sakamako masu yawa. Mafi sau da yawa, suna tsokani bayyanar:

Jerin Magunguna don Ciwon 2

• halayen rashin lafiyan kamar urticaria;
• ciwon ciki
• zawo
• bloating;
• tashin zuciya

An zabi sashi na Novonorm da Starlix daban daban. Ana ɗaukar magani na farko sau 3-4 a rana, kai tsaye kafin cin abinci, na biyu - rabin sa'a kafin abinci.

Biguanides

Hakanan ana samun magunguna daga wannan rukuni ga mutanen da ke fama da ciwon sukari na 2. A cikin abubuwan da suke ciki sun ƙunshi abubuwa masu taimakawa wajen ƙaddamar da glucose daga hanta, haɓaka sha da shiga cikin sel jikin. Koyaya, suna da babban rashi ɗaya - ba za'a iya ɗaukarsu tare da cututtukan da ƙodan da zuciya ba. Amma daidai suke su waɗanda galibi ana gano su a cikin masu ciwon sukari.

Biguanides: cikakken jerin magunguna

Biguanides da sauri yana rage glucose jini kuma zai iya kiyaye shi a cikin iyakoki na al'ada na kimanin sa'o'i 16. A lokaci guda, suna tsoma baki tare da shan kitsen da hanjin ke ciki, ta hakan kan hana faruwar abubuwanda ke faruwa a tasoshin.

Wadannan kwayoyi suna cikin wannan rukunin magungunan:

• Siofor. Yana bayarda daidaituwa na tafiyar matakai na rayuwa da asarar nauyi, sabili da haka mafi yawan lokuta ana wajabta shi ga mutanen da ke da nauyin jiki da yawa. Sashi aka zaɓi akayi daban-daban.
• Metformin. Ana amfani dashi a hade tare da shirye-shiryen insulin kuma a gaban kiba. Aka haɓaka shi cikin cututtukan koda da na ketoacidosis.

Sawarshan

Daga cikin duk magungunan da aka tsara don T2DM, thiazolidinediones sune mafi kyau. Suna bayar da haɓakawa kan aiwatarwa da rarrabuwa da gllu a cikin jiki, kuma suna ba da gudummawa ga daidaituwar hanta. Amma, idan aka kwatanta da sauran magunguna, sun fi tsada kuma suna da jerin kyawawan sakamako masu illa. Daga cikinsu akwai:

• saurin nauyi;
• rage sautin zuciya na zuciya;
• kumburi;
• ƙanshi na ƙasusuwa;
• rashin lafiyan rashes.

Sawarshankar

A yau, waɗannan sababbin magunguna masu zuwa daga rukunin thiazolidinediones galibi ana amfani dasu don maganin T2DM:

• Aktos. Allunan ana amfani dasu azaman monotherapy don T2DM. Bayar da raguwa a cikin tsarin samar da sukari a cikin hanta, kare matakan jini daga lalacewa, inganta wurare dabam dabam na jini, sarrafa matakin glucose a cikin jini. Amma suna da abubuwan ɓarke ​​kansu - suna ba da gudummawa ga haɓaka ci, saboda haka lokacin da aka ɗauke su cikin marasa lafiya, yawanci ana saurin saurin nauyi.
• Avandiya Yana daidaita hanyoyin rayuwa a jiki kuma yana kara karfin jijiyoyin jiki ga insulin. Yana da tasirin hypoglycemic. Yana da magunguna da yawa da ke haifar da sakamako, wanda tabbas za ku fahimci kanku sosai kafin fara jiyya.

Alfa Glucosidase Inhibitors

Daga cikin sababbin magunguna da aka dauka a cikin T2DM, waɗannan sune kawai nau'ikansa da ke hana toshewar wani sinadarin enzyme a cikin hanji wanda ke sauƙaƙe aikin sarrafa hadaddun carbohydrates. Sakamakon wannan, an rage matakin ɗaukar ƙwayar polysaccharides da rage yawan glucose jini.

Mafi shahararrun alfa glucosidase inhibitors har zuwa yau sune:

• Glucobay. An wajabta wa marasa lafiya waɗanda ke lura da tsalle tsalle cikin sukarin jini bayan sun ci abinci. An yarda da shi sosai kuma baya haifar da ƙima mai nauyi. Ana amfani da Glucobai azaman maganin adjuvant kuma dole ne a ƙara haɗarinsa tare da abincin mai-carb.
• Miglitol. Ana amfani dashi don nau'in ciwon sukari na 2, lokacin da abinci da kayan aiki na zahiri basu yarda su sami kyakkyawan sakamako. Ana shan miyagun ƙwayoyi sau 1 a rana, a kan komai a ciki. An zabi sashi ne daban daban. Miglitol yana da contraindications da yawa, daga cikinsu akwai hernias, cututtukan hanji na ciki, ciki, rashin jituwa ga abubuwan, da ƙuruciya.

Glucobay - magani ne mai inganci don T2DM

Incretins

A cikin 'yan shekarun nan, an ƙara yin amfani da incretins, wanda ke cikin ƙungiyar dipeptidyl peptylade inhibitors, a cikin aikin likita. Suna samar da karin insulin da kuma daidaita matakan sukari na jini. Koyaya, basu da mummunar illa a hanta da kodan.

Daga cikin magabata, shahararrun sune:

• Januvius. Wannan magani na T2DM yana da sakamako mai ɗorewa, saboda haka ana ɗaukar lokaci 1 kawai kowace rana. Sashi aka zaɓi akayi daban-daban. Magungunan ba ya haifar da sakamako masu illa kuma yana hana ci gaba da rikice-rikice game da ciwon sukari.
• Galvus. Mayar da ƙwayar ƙwayar ƙwayar cuta mai lalacewa da inganta aikinta. Ana ɗaukar magani kawai a hade tare da abinci da matsakaiciyar motsa jiki. Idan ba su bayar da sakamako mai kyau ba, an haɗa Galvus tare da magunguna masu rage sukari.

Ba za a iya ɗaukar magungunan da aka bayyana a sama ba tare da sanin likita ba. Abubuwan da suke ci suna ba da tallafi ga jiki da rigakafin haɓakar ciwon sukari na 1. Amma, idan mutum da kansa bai bi tsarin makircin su ba, sashi, abinci da motsa jiki a kai a kai, to kuwa babu wani sakamako daga yawan shan su.

Idan an dauki magunguna daidai, amma akwai ƙaruwa na yau da kullun a cikin sukari na jini fiye da 9 mmol / l, lokaci yayi da za a yi tunani game da amfani da samfuran insulin.