Da yake magana game da rikice-rikice masu haɗari da ciwon sukari na iya haifar, mutum ba zai iya kasa ambaci lactic acidosis ba. Wannan cuta tana faruwa da wuya, yiwuwar haɗuwa da ita a cikin shekaru 20 na rayuwa tare da ciwon sukari shine kawai 0.06%.
Rabin rabin marasa lafiyar da suke "sa'a" su fada cikin wannan gutsuttsuran kashi, lactic acidosis mai mutuwa ne. Ana yin bayanin irin wannan babbar mace-mace ta saurin ci gaba da cutar da kuma rashin bayyanannun takamaiman alamun cutar a farkon matakan. Sanin abin da zai iya haifar da lactic acidosis a cikin ciwon sukari, yadda yake bayyana kanta, da abin da za ku yi idan kuna zargin wannan yanayin, zai iya ceci ku ko waɗanda kuke ƙauna.
Lactic acidosis - menene
Lactic acidosis wani cin zarafi ne na glucose metabolism, wanda ke haifar da karuwa a cikin acidity na jini, kuma a sakamakon haka, lalata tasoshin jini, ilimin cututtukan ƙwaƙwalwar ƙwaƙwalwa, haɓakar ƙwaƙwalwar ƙwayar cuta.
A yadda aka saba, glucose da ke shiga jini ya shiga sel kuma ya karye zuwa ruwa da carbon dioxide. A wannan yanayin, ana fitar da makamashi, wanda ke ba da duk ayyukan jikin mutum. A cikin canji tare da carbohydrates, fiye da dozin sunadarai halayen sun faru, kowannensu yana buƙatar yanayi. Mabuɗan enzymes waɗanda ke ba da wannan tsari suna kunna insulin. Idan, saboda ciwon sukari, bai isa ba, ana hana lalacewar glucose a matakin samuwar pyruvate, an canza shi zuwa lactate a adadi mai yawa.
Ciwon sukari da hauhawar jini zai zama abin da ya wuce
- Normalization na sukari -95%
- Cirewa kan jijiyoyin mara wuya - 70%
- Cire zuciyar mai karfin zuciya -90%
- Rabu da cutar hawan jini - 92%
- Increasearuwar kuzarin rana, inganta bacci da dare -97%
A cikin mutane masu lafiya, yanayin lactate a cikin jini bai wuce 1 mmol / l ba, hancinsa da hanta na amfani dashi. Idan ci na lactic acid a cikin jini ya wuce ikon gabobin don cire shi, juyawa cikin ma'aunin acid-tushe na jini zuwa gefen acid yana faruwa, wanda ke haifar da ci gaban lactic acidosis.
Lokacin da lactate a cikin jini ya tara fiye da 4 mmol / l, ƙara yawan hankali a cikin acidity ya zama spasmodic. Halin da ake ciki yana tsananta ta hanyar karuwar jure insulin a cikin yanayin acidic. Rashin haɗarin furotin da mai mai yana haɓakawa da rikice-rikice na metabolism metabolism, matakin ƙwayar mai a cikin jini ya tashi, samfuran metabolism suna tarawa, kuma maye yana faruwa. Jikin ba zai iya sake fita daga wannan da'irar ba da kansa.
Koda likitoci ba koyaushe ba zasu iya tsayar da wannan yanayin ba, kuma ba tare da taimakon likita ba, mummunan lactic acidosis koyaushe yana ƙare da mutuwa.
Dalilin bayyanar
Ciwon sukari mellitus ya yi nisa da dalili guda ɗaya na haɓakar lactic acidosis, a cikin rabin lokuta yana faruwa sakamakon wasu cututtuka masu tsanani.
| Abubuwan haɗari | Sakamakon Cutar Glucose metabolism |
| cutar hanta | na yau da kullun na lalacewar tsarkakewar jini daga lactic acid |
| barasa | |
| lalataccen aikin na koda | gazawa na ɗan lokaci a cikin aikin excretion na lactate |
| sarrafawa na kwatankwacinsa na wakilai na gwaji don gwaje-gwajen x-ray | |
| bugun zuciya | oxygen abinci na kyallen takarda da karuwar samuwar lactic acid |
| cututtuka na numfashi | |
| cuta na jijiyoyin jiki | |
| karancin haemoglobin | |
| haɗuwa da cututtuka da yawa waɗanda ke lalata jiki | jari na lactate saboda dalilai iri daban-daban - duka sunadarai sun karu da karbuwa na lactic acid |
| yana aiki sosai saboda tsufa | |
| da yawa rikitarwa na ciwon sukari | |
| mummunan rauni | |
| mummunan cututtuka | |
| karancin bitamin B1 | m tarewa na carbohydrate metabolism |
Babban haɗarin lactic acidosis a cikin ciwon sukari ya taso idan an haɗa wannan cutar tare da abubuwan haɗari da ke sama.
Metformin, ɗayan magungunan da aka tsara sau da yawa don nau'in ciwon sukari na 2, shima zai iya haifar da rikicewar metabolism. Mafi sau da yawa, lactic acidosis yana haɓaka tare da yawan ƙwayar ƙwayar cuta, amsawar mutum ko tare da tarawa a cikin jiki saboda lalata hanta ko aikin koda.
Alamomin lactic acidosis a cikin nau'ikan 1 da 2 na ciwon sukari
Lactic acidosis yawanci yakan gudana a cikin mummunan tsari. Lokaci daga alamun farko zuwa canje-canje canje-canje a cikin jiki yana ɗaukar sama da yini ɗaya. Daga cikin bayyanar farko na lactic acidosis, ɗaya ne takamaiman - myalgia. Wannan shine ciwon tsoka wanda lalacewa ta haifar. Kowannenmu ya ji sakamakon lactic acid lokacin da muka sake fara motsa jiki bayan dogon hutu. Wadannan abubuwan jin daɗi suna al'ada, na ilimin mutum. Bambanci tsakanin jin zafi tare da lactic acidosis shine cewa ba shi da wata alaƙa da nauyin tsoka.
Tabbatar yin nazarin: >> Metabolic acidosis - me yasa zaka ji tsoron shi?
Sauran alamun cututtukan lactic acidosis ana iya danganta su ga bayyanar wasu cututtuka.
Zai yiwu a lura:
- ciwon kirji
- karancin numfashi
- numfashi akai-akai
- bakin lebe, yatsun, ko hannaye.
- jin cikakken ciki a ciki;
- rikicewar hanji;
- amai
- apathy
- tashin hankalin bacci.
Yayinda matakan lactate ke ƙaruwa, alamu sun tashi waɗanda ke halayyar kawai don rashin lafiyar acidity:
- Kokarin da jiki yayi na inganta iskar oxygen shine yake haifar da tsawa, numfashi mai zurfi.
- Sakamakon bugun zuciya, raguwar matsin lamba da arrhythmia ke faruwa.
- Yawan yawaitar lactate yana tsoratar da jijiyar wuya.
- Rashin wadataccen abinci mai kwakwalwa yana haifar da maye gurbin zafin zuciya tare da barcin ciki, da ɓacin rai da ɓangaren raunin ƙwayoyin mutum zai iya faruwa.
- Samuwar ƙwayar jini, mafi yawan lokuta a cikin gabar jiki.
Idan ba za a iya dakatar da lactic acidosis ba a wannan matakin, mai haƙuri tare da ciwon sukari yana tasowa da rashin lafiya.
Ciplesa'idojin magance cuta
Lokacin da ya sami mai ciwon sukari tare da wani wanda ake zargi da keɓaɓɓen lactic acidosis a cikin cibiyar likitanci, ya yi gwaje-gwaje iri-iri:
- Koma cikin jini. Ana yin bincike idan matakinsa ya wuce 2.2 mol / L.
- Bicarbonates na jini. Aimar da ke ƙasa 22 mmol / L ta tabbatar da lait acidosis.
- Acetone a cikin fitsari an ƙaddara rarrabe acidity saboda lactic acid daga ketoacidosis.
- Halittar jini na ba da izinin bambanta uremic acidosis.
Babban makasudin jiyya shine daidaituwa na yawan zubar jini da kuma kawar da yunwar oxygen.
| Jagorar jiyya | Hanyar | Siffofin |
| Rage zafin jiki | Drip na sodium bicarbonate | An lasafta sashi tare da babban daidaito, ana kulawa da tsarin gudanarwa koyaushe. Ana yin katako da ma'aunin jini a kai a kai, kuma ana yin gwaji na lantarki. |
| Trisamine cikin kayan ciki | Ana amfani dashi maimakon bicarbonate tare da karuwa mai yawa a cikin acidity da kuma haɗarin bugun zuciya, yana da sakamako mai sauri na alkhay. | |
| Katsewa da juyawar pyruvate zuwa lactate | Methylene shuɗi | Abun yana da kaddarorin redox kuma yana iya oxidize enzymes da ke aiki a cikin metabolism metabolism. |
| Hypoxia kawar | Oxygen far | Anyi amfani da iska ta wucin gadi ko kuma isashshen huhun iska. |
| Kammalawa na adadin wuce haddi na metformin | Jin dadi, amfani da sihirin | Ana aiwatar da shi da farko. |
| Tsaya wani mummunan yanayi | Yawaitar Zuciya | Ana amfani da dialysate-free dialysate. |
Yin rigakafin
Don hana lactic acidosis, kuna buƙatar saka idanu akan lafiyar ku koyaushe:
- Bayan shekaru 40, kowane shekaru 3, gudummawar jini ya zama dole don ƙayyade matakin glucose. Lactic acidosis yakan faru ne lokacin da ba'a gano nau'in ciwon sukari na 2 ba, wanda ke nufin cewa babu magani.
- Tare da kamuwa da ciwon sukari, kuna buƙatar bin duk shawarar likita, kuyi binciken likita don gano ainihin abubuwan haɗari don lactic acidosis.
- Idan kuna shan metformin, karanta jerin abubuwan contraindications a cikin umarnin. Idan ɗaya daga cikin cututtukan da aka lissafa a ciki ya faru, kai tsaye tuntuɓi endocrinologist don soke ko daidaita sashi na maganin.
- Kar ku wuce yadda aka ƙayyade maganin Metformin ba tare da izinin likita ba, koda kuwa biyan diyyar cutar sankaran bai isa ba.
Idan kuna fuskantar alamu masu kama da alamun lactic acidosis, kuna buƙatar kiran motar asibiti. Tafiya mai zaman kanta ga likitan halartar ko ƙoƙarin shawo kan cutar da kanku zai iya kawo ƙarshen baƙin ciki.
