Dangane da sabon binciken, estrogen yana taimakawa wajen sarrafa matakin glucose a cikin jiki, har ma da kariya daga nau'in ciwon sukari na 2 a cikin postmenopausal.
Yin nazarin kwayoyin halittar dan adam da beraye a cikin mata masu haihuwa, Jacques Philippe, kwararren masanin cutar sankarau a Jami'ar Geneva a Switzerland, da abokan aikinsa sun fahimci cewa estrogen yana aiki ne a takamaiman sel a cikin cututtukan hanji da hanji, inganta hawan glucose a jiki.
A baya an gano cewa bayan menopause, mata suna da haɗarin kamuwa da cututtukan type 2, wanda canje-canje na hormonal ke haifar dashi, gami da rage haɓakar haɓakar estrogen. Dangane da waɗannan bayanan, masana kimiyya sun yanke shawarar gano ko maganin maye gurbin estrogen zai iya taimakawa hana wannan ci gaban abubuwan, kuma sun sami kyakkyawar amsa.
Estrogen da hanji
A cikin binciken, Filibus da abokan aiki sun allurar isrogen a cikin mice postmenopausal. Abubuwan da suka gabata sun ba da hankali ga yadda estrogen yake aiki akan ƙwayoyin insulin-sel waɗanda suke samar da insulin. Yanzu, masana kimiyya sun mai da hankali kan yadda estrogen ke hulɗa tare da sel waɗanda ke haifar da glucagon, hormone wanda ke haɓaka matakan glucose na jini.
Dangane da sabon binciken, sel alcer pant na samar da glucagon suna da matukar damuwa ga estrogen. Yana sa waɗannan sel su saki ƙasa da glucagon, amma ƙarin hormone da ake kira glucagon-like peptide 1 (HLP1).
GLP1 yana haɓaka samar da insulin, yana toshe asirin glucagon, yana haifar da jin daɗin satiety, kuma ana samarwa cikin hanji.
“Tabbas, akwai sel na L a cikin hanjin da ke da kama da na sikila, kuma babban aikinsu shi ne samar da GP1,” in ji Sandra Handgraaf, daya daga cikin marubutan binciken. "Gaskiyar cewa mun lura da gagarumin ci gaba a cikin samar da GLP1 a cikin hanji yana nuna yadda wannan sashin jiki yake taka rawa wajen sarrafa daidaituwar carbohydrate kuma yaya girman tasirin estrogen yake a kan tsarin rayuwa gaba daya," in ji Sandra.
A jikin sel, an tabbatar da sakamakon binciken.
Sauya jijiya a matsayin kayan aiki akan cutar siga
A da canjin magani na huhu an riga an danganta shi da haɗari iri iri ga lafiyar mata masu haihuwa, alal misali, ci gaban cututtukan zuciya.
"Idan kun dauki kwayoyin homoni sama da shekaru 10 bayan haila, lalle wannan hadarin yana ƙaruwa sosai," in ji Philip. Ya kara da cewa, "idan aka dauki magani na hormone na wasu 'yan shekaru nan da nan bayan farawar menopause, babu wata illa da zazzabi ga tsarin zuciya, kuma ana iya hana nau'in ciwon sukari na 2. Don haka, ingantaccen tsarin isrogen din zai kawo babban fa'idodi ga lafiyar mata, musamman dangane da hana kamuwa da cutar siga, "in ji masanin.
