Alpha lipoic acid, wanda kuma aka sani da thioctic acid, ya kasance farkon ware daga hanta a cikin 1950. Ta hanyar tsarinta mai guba, mai ce mai kitse mai dauke da sinadarin sulfur. Ana iya samunsa a cikin kowane sel a jikin mu, inda yake taimakawa samar da makamashi. Alpha lipoic acid shine maɓalli na tsarin metabolic, wanda ke canza glucose zuwa makamashi don bukatun jiki. Acio acid acid shima antioxidant ne - yana magance sinadarai masu cutarwa da aka sani da tsattsauran ra'ayi.
Bayar da muhimmiyar rawar da ta taka a cikin tsarin kwayoyin halitta, alpha-lipoic acid ya kasance asali an haɗa shi cikin hadaddun bitamin na rukunin B. Duk da haka, a halin yanzu ba a ɗaukar bitamin. An yi imanin shine mafi kyawun maganin antioxidant wanda aka siyar dashi azaman kari.
Amfanin tsarin na zuciya daga shan alpha-lipoic acid ya yi daidai da fa'idodin da kifin mai ke da shi. Masana cututtukan zuciya a Yammacin Turai, waɗanda a baya sun ɗauki bitamin E a matsayin maganin antioxidant kuma don rigakafin cututtukan zuciya, yanzu suna jujjuya su zuwa acid na thioctic.
A cikin wane allurai ne ake shan wannan magani
Don rigakafi da magani na rikice-rikice na nau'in 1 ko 2 na ciwon sukari, ana sanya wani magani alpha-lipoic acid a wasu lokuta a cikin allunan ko maganin kwalliya a cikin sashi na 100-200 mg sau uku a rana. Dos na 600 MG sun fi yawa, kuma irin waɗannan kwayoyi suna buƙatar ɗaukar sau ɗaya kawai a rana, wanda yafi dacewa. Idan kun zaɓi kari na zamani na R-lipoic acid, to lallai suna buƙatar ɗauka a cikin ƙananan allurai - 100 mg 1-2 sau a rana. Wannan ya shafi musamman shirye-shiryen da suka ƙunshi Ac-Enhanced® R-Lipoic Acid na GeroNova. Karanta ƙarin game da su a ƙasa.
An ba da rahoton cin abinci don rage bioavailability na alpha lipoic acid. Don haka, ana buƙatar ɗaukar wannan ƙarin akan komai a ciki, awa 1 kafin ko sa'o'i 2 bayan cin abinci.
Idan don kula da cututtukan cututtukan ƙwayar cutar hanji kuna son karɓar thioctic acid a cikin ciki, to, likita zai ba da umarnin sashi. Don rigakafin gabaɗaya, alpha-lipoic acid yawanci ana ɗauka azaman ɓangare na hadaddun multivitamin, a cikin sashi na 20-50 MG kowace rana. Zuwa yau, babu wani tabbataccen shaida da ke nuna cewa ɗaukar wannan maganin ta hanyar wannan hanyar yana ba da duk fa'idodin kiwon lafiya.
Me yasa ake buƙatar maganin antioxidants
An yi imanin cewa rashin lafiya da tsufa suna da alaƙa a cikin ɓangaren ƙananan abubuwa ta hanyar iska mai lalacewa, wanda ke faruwa azaman samfurori ta abubuwa lokacin iskar shaka (“ƙonewa”) halayen da ke cikin jiki. Sakamakon gaskiyar cewa alpha lipoic acid yana narkewa a cikin ruwa da mai, yana aiki azaman maganin antioxidant a matakai daban-daban na metabolism kuma yana iya kare sel daga lalacewa ta hanyar tsattsauran ra'ayi. Ba kamar sauran magungunan antioxidants ba, waɗanda suke narkewa kawai a ruwa ko mai, alpha lipoic acid ayyuka a ruwa da mai. Wannan shine mallakinta na musamman. A kwatankwacin, bitamin E yana aiki ne a cikin mai, da kuma bitamin C kawai cikin ruwa. Sinadarin Thioctic acid yana da tsaka-tsakin bakan duniya na tasirin kariya.
Antioxidants suna kama da matukan jirgi kamikaze. Sun sadaukar da kansu don kawar da tsattsauran ra'ayi. Ofaya daga cikin abubuwan da ke da ban sha'awa na alpha lipoic acid shine cewa yana taimakawa wajen sake dawo da sauran magungunan ƙwayoyin cuta bayan an yi amfani dasu don manufar da aka nufa. Bugu da kari, zai iya yin aikin sauran maganin maye idan jiki ya gaza a cikinsu.
Alfa Lipoic Acid - Cikakken Antioxidant
Tabbataccen maganin warkewa yakamata ya cika sharuɗan da yawa. Waɗannan sharuɗɗan sun haɗa da:
- Tsotsa daga abinci.
- Canji a cikin sel da kyallen takarda ya zama mai amfani.
- Yawancin ayyuka na kariya, ciki har da hulɗa tare da sauran antioxidants a cikin membranes cell da sarari intercellular.
- Toarancin guba.
Alpha lipoic acid na musamman ne tsakanin antioxidants na halitta saboda yana biyan duk waɗannan buƙatu. Wannan yana sanya shi mai yuwuwar ingantacciyar wakili na warkarwa don magance matsalolin kiwon lafiya waɗanda ke haifar, a tsakanin wasu, ta hanyar lalacewa ta hanyar lalacewa.
Acid na Thioctic yana aiwatar da ayyukan kariya masu zuwa:
- Kai tsaye neutralizes kawo hadari mai dauke oxygen abubuwa (free radicals).
- Yana maido da antioxidant na antioxidants, kamar su glutathione, bitamin E da C, don sake amfani da shi.
- Yana ɗaure (cukulan) karafa mai guba a cikin jikin mutum, wanda ke haifar da raguwa a cikin samarwa masu tsattsauran ra'ayi kyauta.
Wannan kayan yana taka muhimmiyar rawa wajen kiyaye daidaiton abubuwan da ke maganin antioxidant - tsarin da ake kira cibiyar tsaro ta hanayar iska. Acioctic acid kai tsaye yana mayar da bitamin C, glutathione da coenzyme Q10, yana ba su damar shiga cikin metabolism na jiki ya fi tsayi. Hakanan yana mayar da bitamin E. kai tsaye, an ba da rahoton ƙara yawan kwayar glutathione a cikin jikin tsofaffin dabbobi. Wannan saboda tasirin salula na cysteine, amino acid wanda ya cancanta don haɗuwar glutathione, yana ƙaruwa. Koyaya, har yanzu ba a tabbatar dashi ba ko a zahiri alpha lipoic acid yana taka muhimmiyar rawa wajen sarrafa ayyukan sake fasalin a cikin sel.
Matsayi a jikin mutum
A cikin jikin mutum, alpha-lipoic acid (a zahiri, kawai shine R-form, karanta ƙari a ƙasa) an haɗa shi a cikin hanta da sauran kyallen takarda, sannan kuma ya fito ne daga abincin dabbobi da shuka. R-lipoic acid a cikin abinci yana cikin nau'in da ke hade da amino acid lysine a cikin sunadarai. Ana samun babban haɗuwa da wannan antioxidant a cikin kyallen dabbobi, waɗanda ke da babban aiki na rayuwa. Wannan ita ce zuciya, hanta da kodan. Babban tushen tsire-tsire sune alayyafo, broccoli, tumatir, Peas lambu, fure na Brussels, da kuma shinkafa.
Ba kamar R-lipoic acid ba, wanda aka samo a abinci, maganin alpha-lipoic acid a cikin kwayoyi yana kunshe ne da tsari na kyauta, i.e., ba a ɗaure shi da sunadarai ba. Kari akan haka, allurai da suke cikin allunan da injections na ciki (200-600 mg) sunfi 1000 girma fiye da wadanda mutane ke samu daga abincinsu. A Jamus, maganin thioctic acid shine izini wanda aka yarda da shi don maganin cututtukan cututtukan cututtukan daji, kuma yana nan azaman takardar sayan magani. A cikin Amurka da ƙasashen masu magana da Rasha, zaku iya siyan sayo a kantin magani kamar yadda likita ya umarta ko azaman karin abinci.
Acid na Alpo Lipoic Acid na R-ALA
Alpha-lipoic acid yana cikin nau'ikan kwayoyin halitta guda biyu - dama (R) da hagu (ana kiran shi L, wani lokacin kuma a rubuce S). Tun daga 1980s, magunguna da kayan abinci masu guba sun kasance cakuda waɗannan siffofin guda biyu cikin rabo 50/50. Sannan masana kimiyya sun gano cewa tsarin aiki mai adalci ne kawai (R). A jikin mutum da sauran dabbobi a vivo kawai aka samar da kuma amfani. An tsara shi azaman R-lipoic acid, cikin Turanci R-ALA.
Har yanzu akwai tarin fuka-fukan na alpha lipoic acid, wanda shine cakuda “dama” da “hagu,” kowane daidai. Amma sannu a hankali ana matse shi daga kasuwa ta abubuwa masu ƙara waɗanda suke ɗauke da guda “daidai”. Dr. Bernstein da kansa yana ɗaukar R-ALA kuma yana tsara marasa lafiya kawai ga masu haƙuri. Nazarin abokin ciniki a cikin shagunan kan layi na Ingilishi yana tabbatar da cewa R-lipoic acid ya fi tasiri. Biye da Dr. Bernstein, muna ba da shawarar zabar R-ALA maimakon maganin gargajiya na alpha lipoic acid.
R-lipoic acid (R-ALA) wani nau'in halitta ne na alpha-lipoic acid wanda tsirrai da dabbobi ke haɗawa da amfani da shi ƙarƙashin yanayin halitta. L-lipoic acid - wucin gadi, roba. Maganin gargajiya na gargajiya na alpha-lipoic acid cakuda magani ne na L- da R-bambance-bambancen, a cikin rabo na 50/50. Sabbin abubuwan itiveara abubuwa sun ƙunshi R-lipoic acid kawai, R-ALA ko R-LA an rubuta akan su.
Abin takaici, kwatancen kai tsaye na tasirin bambance-bambance masu hade da R-ALA har yanzu ba a sanya su ba kuma aka buga su. Bayan ɗaukar allunan "gauraye", mafi girman ƙwayar plasma na R-lipoic acid shine 40-50% sama da nau'in L-form. Wannan yana nuna cewa R-lipoic acid ya fi dacewa da shaye-shaye na L. Duk da haka, dukkanin waɗannan nau'ikan acid na thioctic acid suna da sauri kuma an cire su. Kusan duk nazarin da aka wallafa game da tasirin alpha-lipoic acid akan jikin ɗan adam an yi shi har zuwa 2008 kuma kawai an yi amfani da ƙarin kayan maye.
Nazarin abokin ciniki, wanda ya haɗa da masu ciwon sukari, ya tabbatar da cewa R-lipoic acid (R-ALA) ya fi tasiri a cikin gargajiya na cakuda alpha-lipoic acid. Amma a hukumance ba a tabbatar da hakan ba tukuna. R-lipoic acid wata dabi'a ce ta jiki - jikinta ne yake samarwa kuma yake amfani. R-lipoic acid yafi ƙarfin acid na yau da kullun, saboda jiki "ya gane" shi kuma nan da nan yasan yadda ake amfani dashi. Masana'antu suna da'awar cewa jikin ɗan adam yana iya ɗaukar nau'in nau'in L-na halitta, kuma yana iya kawo cikas ga aiki mai kyau na R-lipoic acid.
A cikin 'yan shekarun nan, kamfanin GeroNova, wanda ke samar da "tsayayyen" R-lipoic acid, shine ya jagoranci a duniyar Turanci. Ana cewa shi Bio-Enhanced® R-Lipoic Acid, watau an inganta shi akan R-ALA na al'ada. Pleararrakin abinci zaku iya yin umarni don magance cututtukan cututtukan zuciya wanda ke amfani da gishirin sodium da ake kira BioEnhanced® Na-RALA. Ta shiga wani yanayi na musamman na ingantawa, wanda GeroNova har ma ya yi tallafi. Saboda wannan, narkewar acid-Enhanced® R-lipoic acid ya karu sau 40.
A yayin daidaitawa, ana amfani da karafa mai guba da sauran abubuwan hutu a cikin abinci. GeroNova's Bio-Enhanced® R-Lipoic Acid shine mafi ingancin alpha lipoic acid. Ana tsammanin cewa ɗaukar wannan ƙarin a cikin capsules yana da tasirin sakamako mara kyau fiye da gudanarwar maganin ƙwayoyin cuta na thioctic acid tare da masu amfani da ruwa.
GeroNova shine masana'antar samar da acid alfa lipoic acid. Kuma sauran kamfanoni: Mafi kyawun Likita, Tsawan Rayuwa, Jarrow Formulas da sauransu, suna tattarawa suna siyarwa ga mai siye na ƙarshe. A shafin yanar gizon GeroNova an rubuta cewa mafi yawan mutane bayan sati biyu na lura da cewa sun karu da karfi da ingantaccen tunani. Koda yake, an bada shawarar shan R-lipoic acid na tsawon watanni biyu, sannan kuma yanke shawara ta ƙarshe yadda amfanin wannan ƙarin aikin ya zama muku.
- Mafi kyawun kwayoyin Biotin R-Lipoic na Dr;
- R-lipoic acid - karuwar sashi na Tsawan rayuwa;
- Allunan Jarwaƙwalwar rowwayar Jarrow.
A matsayinka na mai mulkin, mutane suna iya hada isasshen alpha lipoic acid don gamsar da bukatun jikinsu da hakan. Koyaya, haɗin wannan abu yana raguwa tare da shekaru, da kuma a cikin mutanen da ke da matsalolin kiwon lafiya, ciki har da ciwon sukari da rikitarwarsa, irin su neuropathy. A cikin waɗannan halayen, ƙarin thioctic acid, yana iya zama kyawawa don samun daga kafofin waje - daga kayan abinci a cikin capsules ko injections na ciki.
Gudanar da ciwon sukari: Cikakkun bayanai
Alpha lipoic acid yana da sakamako mai amfani a cikin yanayi mai raɗaɗi - ciwon sukari, sclerosis da yawa, rage ƙwaƙwalwar hankali da ƙarancin ciki. Tunda muna da shafi game da lura da ciwon sukari, a ƙasa zamuyi nazarin yadda tasirin thioctic acid yake a cikin nau'in 1 da nau'in ciwon sukari na 2 don rigakafi da magani na rikitarwa. Kawai lura cewa wannan antioxidant yana da damar magance yawancin matsalolin kiwon lafiyar da cutar sankara ke haifar. Ka tuna cewa tare da nau'in ciwon sukari na 1, ragewar insulin yana raguwa sosai saboda lalata sel. A nau'in ciwon sukari na 2, babbar matsalar ba ita ce karancin insulin ba, amma juriya ne na tsageran nama.
An tabbatar da cewa rikice-rikice na ciwon sukari ana haifar da lalacewa ta hanyar ƙwayar cuta saboda damuwa na damuwa. Wannan na iya zama saboda haɓaka aikin samar da tsattsauran ra'ayi ko raguwa a cikin kariyar maganin kariya. Akwai shaidu masu ƙarfi cewa damuwa na iskar shaye shaye yana taka muhimmiyar rawa a haɓakar rikice-rikicen ciwon sukari. Takaitaccen sukari na jini yana haifar da karuwa a cikin haɗarin nau'in oxygen mai haɗari. Damuwa na Oxidative ba kawai yana haifar da rikicewar ciwon sukari ba, amma ana iya haɗa shi da juriya na insulin. Alpha lipoic acid na iya samun sakamako mai illa da warkewa akan fannoni daban-daban na nau'in 1 da nau'in ciwon sukari na 2.
Nau'in nau'in 1 an kamu da shi ta wucin gadi a cikin ɗakin gwaje-gwaje ta amfani da cyclophosphamide. A lokaci guda, an allura dasu da maganin alpha-lipoic a 10 MG a kilogiram 1 na nauyin jiki na kwana 10. Ya juya cewa yawan mice da suka kamu da ciwon sukari ya ragu da 50%. Masana ilimin kimiyya kuma sun gano cewa wannan kayan aiki yana ƙara yawan amfani da glucose a cikin kyallen bera - diaphragm, zuciya da tsokoki.
Yawancin rikice-rikicen da ke haifar da ciwon sukari, ciki har da neuropathy da cataract, suna fitowa ne sakamakon karuwar samar da nau'ikan oxygen masu aiki a cikin jiki. Bugu da kari, ana tunanin cewa matsalar damuwa na shaye shaye na iya zama farkon abin da ya faru a cikin ilimin cututtukan cututtukan cututtukan siga, kuma daga baya ya shafi abin da ya faru da ci gaban rikice-rikice. Binciken marasa lafiya na 107 da ke da nau'in 1 da nau'in ciwon sukari 2 ya nuna cewa waɗanda suka dauki alpha-lipoic acid a cikin 600 MG a kowace rana don watanni 3 sun rage damuwa da iskar shaye shaye idan aka kwatanta da waɗanda ke fama da cutar sankara waɗanda ba a sanya musu maganin antioxidant ba. An bayyana wannan sakamakon ne koda kuwa yawan karfin sukari na jini bai yi kyau ba kuma isowar furotin a cikin fitsari tayi yawa.
Sensara ƙwaƙwalwar insulin
Theaukar insulin ga masu karɓar sa, waɗanda ke kan saman membranes, suna haifar da motsin masu kai gulukos (GLUT-4) daga ciki zuwa ƙwayoyin sel kuma yana ƙaruwa da haɓaka glucose ta sel daga magudanar jini. An samo Alpha-lipoic acid don kunna GLUT-4 kuma ƙara haɓaka glucose ta hanyar adipose da ƙwayoyin tsoka. Ya juya cewa yana da tasiri guda ɗaya kamar insulin, kodayake sau da yawa rauni. Gashin tsokoki sune babban tsoratarwar glucose. Acid na Thioctic yana kara yawan ƙwayar tsoka mai narkewa. Yana da yuwuwar amfani a cikin jiyya na dogon lokaci na nau'in ciwon sukari na 2.
Koyaya, bincike ya nuna cewa, sabanin gudanarwar cikin jijiya, bayan shan allunan a bakin, kawai an sami ci gaba kaɗan cikin hankalin jijiyoyin ga insulin (<20%). Ba zai yiwu ba a sami gagarumin ƙaruwa a cikin ƙwayar insulin har ma da babban allurai, har zuwa 1800 MG kowace rana, kuma tare da tsawon lokacin magani, kwanaki 30 na ɗaukar allunan a ranar 10 na jijiyoyin jini. Ka tuna cewa duk wannan bayanai ne daga tsoffin binciken na 1990s, lokacin da babu wani ƙari na R-lipoic acid, har ma ƙari don haka aka ba da izini na GeroNova Bio-Enhanced® R-Lipoic Acid. Sabbin nau'ikan acid na alpha-lipoic a cikin capsules da allunan suna ba da sakamako kwatankwacin wanda aka samu daga injections na ciki.
Ciwon mara mai cutar kansa
A nau'in 1 da nau'in 2 na ciwon sukari, neuropathy yana faruwa saboda guduwar jini yana da damuwa kuma hanyar motsa jijiyoyi ta lalace. Nazarin dabbobi masu gwaji sun gano cewa magani tare da alpha lipoic acid yana inganta hawan jini da jijiyoyin jijiyoyi.Wadannan sakamako masu kyau sun karawa masana kimiyya kwarin gwiwar gudanar da gwaji na asibiti a cikin mutanen da ke dauke da cutar siga. An fara amfani da maganin Thioctic acid don magance cututtukan cututtukan zuciya a cikin Jamus fiye da shekaru 30 da suka gabata. An yarda da shi azaman magani, duk da cewa a wancan lokacin har yanzu babu isasshen bayani game da abubuwan da ke haifar da cutar sankara. An yi imani cewa wannan kayan aiki yana ƙaruwa da amfani da glucose a cikin jijiyoyin gefe.
A cikin ciwon sukari mai ciwon sukari, mai haƙuri yana jin ƙarancin magana, jin zafi da sauran alamu mara kyau. Ana zaton cewa matsalar damuwa da iskar shaka da kuma tsattsauran ra'ayi na taka rawa sosai ga ci gaban wannan rikitarwa. Idan haka ne, to sai a magance cutar da magungunan kashe kwayoyin cuta. Kamar yadda muka bayyana a sama a cikin labarin, alpha lipoic acid shine maganin antioxidant mai ƙarfi. Koyaya, an samo tabbatacciyar shaidar ingancinsa ne kawai a cikin karatun da aka gudanar da wannan magani ga masu ciwon sukari cikin hanji, kuma ba a cikin allunan da baki ba.
An gudanar da manyan karatun har zuwa 2007. Daga baya, kayan abinci na gaba wanda ke dauke da kawai R-lipoic acid ya fara bayyana a kasuwa, wannan shine isomer na alpha-lipoic acid. Irin waɗannan abubuwan ƙari ba su da acid-lipoic acid mara amfani, yayin da shirye-shiryen gargajiya suka ƙunshi nau'in R-da L na 50% kowannensu. Ana tsammanin allunan zamani da capsules na alpha-lipoic acid suna da tasiri sosai, kwatankwacin masu zubar da ciki, yayin guje wa allura. Koyaya, wannan zato ya samo asali ne kawai daga bayanan da masana masana'antu, Dr. Bernstein, da yawaitar kwastomomi masu yawa na shagunan Ingilishi kan layi. Ba a gudanar da nazarin tsari na sababbin magunguna na R-lipoic acid ba.
Tare da ciwon sukari, sauran jijiyoyi a jikin mutum kuma sun lalace, wato jijiyoyi masu ƙoshin ƙarfi wanda ke kula da gabobin ciki. Idan wannan ya faru a cikin zuciya, to, ciwon neuropathy yana haɓaka, wanda ke haifar da arrhythmias na zuciya. Autonomic neuropathy cuta ce mai haɗarin kamuwa da cutar sankara, tare da babban haɗarin mutuwa kwatsam. Akwai wasu hujjoji cewa alpha lipoic acid supplements na iya taimakawa wajen rage ci gaba da kuma magance wannan cutar.
Bayanan farko da kuma rikice-rikice sun ba da shawarar cewa shan alpha-lipoic acid na iya inganta ba kawai hanyar neuropathy ba, har ma da sauran fannoni na ciwon sukari. Acioctic acid dan kadan yana inganta kula da sukari na jini kuma yana taimakawa ci gaban rikicewar jijiyoyin jiki - cututtukan zuciya, kodan da ƙananan jijiyoyin jini. Muna tunatar da ku cewa babbar hanyar hanawa da magance rikice-rikice na nau'in 1 da nau'in ciwon sukari na 2 shine rage cin abinci mai-carbohydrate. Yi amfani da kari kawai ban da shi.
A cikin 1995-2006, an gudanar da gwaje-gwaje na asibiti da yawa don kimanta tasiri na alpha lipoic acid don magance cututtukan cututtukan cututtukan zuciya.
Taken Nazari | Yawan marasa lafiya masu ciwon sukari | Sashi na alpha lipoic acid, mg | Tsawon Lokaci |
---|---|---|---|
Aladin | 328 | 100/600/1200 / placebo | Makonni 3 cikin ciki |
ALADIN II | 65 | 600/1200 / placebo | Shekaru 2 - Allunan, alli |
ALADIN III | 508 | 600 intravenously / 1800 ta bakin / placebo | Makonni 3 a ciki, to, magungunan watanni 6 |
DEKAN | 73 | 800 / placebo | 4 kwaya |
KOYA | 24 | 1800 / placebo | Kwayoyin makonni 3 |
Duk waɗannan sun kasance makafi-biyu, nazarin sarrafa-sarrafa mutum, i.e., wanda aka gudanar zuwa mafi girman matsayin. Abin takaici, masana kimiyya basu sami wata hujja ba cewa shan kwayoyi a kalla dan kadan yana inganta sarrafa sukari na jini a cikin ciwon sukari. Bayan haka, an tabbatar da cewa amfani da glucose da kwayoyin halitta yayi yawa. Don haka, duk da wasu bambance-bambance na ra'ayi tsakanin masana kimiyya, akwai hujja na asibiti cewa alpha lipoic acid yana inganta hanya ta ciwon suga. Musamman sakamako mai kyau, idan ka shigar dashi ciki, har ma a babban allurai kuma na dogon lokaci.
Kayan ruwan R-lipoic acid na zamani, gami da GeroNova na Bio-Enhanced® R-Lipoic Acid, ya fara bayyana ne bayan shekarar 2008. A cikin karatun da muka ambata a sama, ba su shiga ba. An yi imanin suyi kyau sosai fiye da shirye-shiryen alpha-lipoic acid na baya, waɗanda sune cakuda isomers R-da L- (S-). Zai yuwu koda shan magungunan na iya samun sakamako kwatankwacin wanda aka bayar ta allura ta hanji. Abin baƙin ciki, a lokacin wannan rubutun (Yuli 2014), ƙarin gwajin asibiti na kwanan nan ba tukuna har yanzu.
Idan kuna shirin ɗaukar allurar ciki ta alpha lipoic acid, to a maimakon haka sai a ɗauki allurai Bio-Enhanced® R-Lipoic Acid capsules daga GeroNova, wanda Kwakwarar Likita yake, Yaɗaitar Rayuwa, ko kuma Jarrow Formulas sustain-kani kwaya maimakon.
- Mafi kyawun kwayoyin Biotin R-Lipoic na Dr;
- R-lipoic acid - karuwar sashi na Tsawan rayuwa;
- Allunan Jarwaƙwalwar rowwayar Jarrow.
Wataƙila zai yi aiki sosai cewa ba'a buƙatar masu sauke farashi. A lokaci guda, muna tuna cewa babban magani ga masu ciwon sukari shine rage cin abinci mai-carbohydrate. Ciwon sukari mai narkewa cuta ce gaba daya ta rikicewa. Idan ka saba da sukarin jininka tare da tsarin karancin carbohydrate, to dukkan alamu zasu tafi daga 'yan watanni zuwa shekaru 3. Wataƙila shan alpha lipoic acid zai taimaka saurin wannan. Amma babu kwayoyin hana daukar ciki da injections da gaske suke aiki har sai abincinku ya cika sosai da abubuwan carbohydrates masu cutarwa.
Side effects
Jiyya tare da alpha lipoic acid yawanci ana haƙuri da kyau, kuma mummunan sakamako masu illa ne. A tunani, tashin zuciya ko ciwon ciki, da yawan kumburi, gajiya, ko rashin bacci na iya faruwa, amma a aikace yuwuwar hakan yana zartar. Babban allurai na miyagun ƙwayoyi na iya rage ƙarin jini. Wannan yana da amfani yawanci ga marasa lafiya da ciwon sukari, amma yana buƙatar saka idanu sosai game da matakan glucose. Hadarin hypoglycemia yana ƙaruwa idan mai ciwon sukari ya riga ya fara ɗaukar hanyoyin maganin sulfonylurea ko ɗaukar alluran insulin, kuma yanzu yana ƙara alpha-lipoic acid a cikin wannan.
600 MG kowace rana shine amintaccen magani kuma ana bada shawara ga masu ciwon sukari. A mafi yawan matakai, marasa lafiya da wuya suna da alamun cututtukan gastrointestinal: zafin ciki, tashin zuciya, amai, kazalika da zawo da zazzabin cizon sauro, ciki har da laryngospasm. Bugu da kari, an bayar da rahoton halayen rashin lafiyan, wadanda suka hada da fuka, urtikaria, da itching na fata. Mutanen da suke shan allunan acid na sitio a wani kashi na 1200 a kowace rana na iya samun warin fitsari mara dadi.
Shan alpha-lipoic acid a cikin allunan ko ruwan 'dusoshin yana lalata biotin a jiki. Biotin yana daya daga cikin bitamin-mai narkewa na ruwa na rukunin B. Wani bangare ne na enzymes wanda ke tsara yanayin metabolism da kitsen. Tare da alpha lipoic acid, ana kuma bada shawara don ɗaukar biotin a cikin adadin 1%. Lura cewa kayan abincin R-lipoic acid na zamani muna bada shawarar suma suna da sinadarin biotin.
- Mafi kyawun kwayoyin Biotin R-Lipoic na Dr;
- R-lipoic acid - karuwar sashi na Tsawan rayuwa;
- Allunan Jarwaƙwalwar rowwayar Jarrow.
Babban matsalar ita ce kusan kudin da ake kashewa game da wannan cutar ta sukari. Kashi na yau da kullun zai cinye ku aƙalla $ 0.3. Kuma babu wanda zai iya bada tabbacin a gaba cewa zaku sami babban tasiri na wannan kudin. Har yanzu, babbar hanyar da za a bi don magance cututtukan cututtukan cututtukan zuciya da sauran rikice-rikice na nau'in 1 da nau'in ciwon sukari na 2 kyauta ne, mai gamsarwa da jin dadi maras-carbohydrate. Alpha lipoic acid kawai ya cika shi. Ana ba da shawarar cewa zai hanzarta inganta sauƙi daga alamun neuropathy. Idan abincin mai ciwon sukari ya kasance yana cike da carbohydrates, to shan kayan abinci haramun ne.
Kwayoyin ko digo-wanne ne mafi kyau?
Me yasa maganin gargajiya “gauraye” alpha lipoic acid bashi da tasirin gaske idan aka ɗauke shi a allunan ko kuma capsules? Yana dan ƙara haɓakar jiɓuwar sel zuwa insulin kuma kusan ba shi da tasiri ga matakan sukari na jini. Me yasa hakan ke faruwa? Ayan bayani mai yiwuwa na iya kasancewa cewa babban maganin warkewar ƙwayoyi a cikin jini an kiyaye shi na ɗan gajeren lokaci. Acid na Thioctic yana da ɗan gajeren rabin rai a jiki, kimanin minti 30. Mafi girman abincinta a cikin jini ana lura da mintuna 30-60 bayan fitowar. Ana saukeshi cikin hanzari zuwa cikin jini, amma sannan kuma ana aiwatar dashi da sauri kuma cire shi daga jiki.
Bayan kashi ɗaya na 200 MG, bioavailability na miyagun ƙwayoyi ya kusan 30%. Koda bayan kwanakin da yawa na ci gaba da cin Allunan, tarawar abu mai aiki a cikin jini baya faruwa. An fi mayar da hankali a cikin plasma cikin sauri, amma bayan haka ya faɗi kamar sauri, zuwa matakin da bai isa ba don shafan hankalin ƙwayoyin sel zuwa insulin ko sarrafa glucose. Me yasa gudanarwar maganin ƙwayoyin cuta na thioctic acid yayi aiki sosai fiye da allunan? Wataƙila saboda kashi na miyagun ƙwayoyi ba ya shiga jiki nan da nan, amma a hankali, a cikin mintuna 30 zuwa 40, yayin da mutum yake kwance a ƙarƙashin maƙogwaro.
Wani labarin Turanci na 2008 ya ambaci cewa masana kimiyya sun tattara kashi na alpha lipoic acid a cikin kwamfutar hannu da aka saki mai dacewa. Wannan yana ba ku damar kula da ƙwayar cutar a cikin jini na awa 12. Abin baƙin ciki, ƙarin labarai na kwanan nan game da yadda tasirin wannan hanyar ya zama ba za a iya samu ba. Kuna iya gwada Jarrow Formulas ci gaba da sakin alpha lipoic acid. Nazarin abokin ciniki ya tabbatar da babban ingancinsa, amma babu cikakken bayani game da haka. Idan cututtukan cututtukan zuciyarku suna nunawa ta hanyar gastroparesis, i.e., saki mai saukar da ciki, to tabbas wannan magani ba shi da amfani. Karanta karin bayani kan labarin “Ciwon koda.”.
Shin ya cancanci siyan alpha lipoic acid a cikin kantin magani?
A cikin ƙasashen da ke magana da Rasha akwai dubun dubatar mutane waɗanda ke fama da ciwon sukari na cutar sankara. Dukkansu suna matukar bukatar kawar da alamun su, kuma yana da kyau a murmure gaba daya. Alpha-lipoic acid (aka thioctic acid) shine kawai magani wanda za'a iya amfani dashi don neuropathy ban da hanyoyin sarrafa cututtukan fata na gaba ɗaya. Ba abin mamaki bane cewa shirye-shiryenta suna cikin babbar buƙata a tsakanin marasa lafiya, duk da babban farashinta.
Magungunan gargajiya na alpha-lipoic acid da aka sayar a cikin magunguna:
- Lirƙirari;
- Lipamide;
- Lipothioxone;
- Neuroleipone;
- Oktolipen;
- Thiogamma;
- Thioctacid;
- Tiolepta;
- Thiolipone;
- Espa Lipon.
Masana'antu suna tallata waɗannan allunan da kuma mafita don gudanar da jijiyoyin jini a tsakanin marasa lafiya da masu ciwon sukari da kuma tsakanin likitoci. Koyaya, muna ba da shawarar cewa kar ku sayi alpha lipoic acid a cikin kantin magani, amma kuyi oda ta kan layi daga Amurka (karanta yadda ake yin hakan). Ta wannan hanyar, zaku sami fa'idodin gaske don kuɗin ku. Masu ciwon sukari waɗanda ke shan magani a lokaci-lokaci tare da ƙwayoyin alpha-lipoic acid na iya canzawa zuwa zamani, ingantattun maganin kafe da allunan. Babu shakka, wannan yafi dacewa, har ma da araha.
'Yan ƙwararrun likitocin Rasha da ke fama da cutar sankara sun san cewa alpha-lipoic acid ya wanzu a cikin kwayoyin halitta guda biyu (isomers) - dama (R) da hagu, wanda L- ko S- suka musanta. Ana amfani da shirye-shiryen acid na Thioctic don magance cututtukan cututtukan cututtukan zuciya tun daga shekarun 1970. Waɗannan na iya zama magunguna ko kuma magunguna waɗanda ake samu kyauta a kan mai sayar da kaya. Har kwanan nan, duk sun ƙunshi cakuda R-da L-isomers a cikin rabo 1: 1. Sannan masana kimiyya sun gano cewa kawai R-nau'i na alpha lipoic acid yana da amfani don dalilai na likita. Don ƙarin game da wannan, karanta labarin Wikipedia a Turanci.
Shirye-shiryen acid na Thioctic acid, wanda aka haɗa a cikin rabin nau'ikan R da L, har yanzu suna yaɗu. A cikin kantin magunguna na ƙasashen da ke magana da Rasha, kawai ana sayar da su. Koyaya, a cikin Yammacin Turai ana maye gurbinsu da ƙari ta hanyar ƙarawa waɗanda ke ɗauke da kawai acid-lipoic acid. Nazarin marasa lafiya na masu magana da harshen Rashanci tare da ciwon sukari sun nuna cewa shan allunan acid na alpha-lipoic ba shi da amfani, amma gudanar da jiyya kawai yana taimakawa sosai. A lokaci guda, a cikin ƙasashe masu wayewa, masu ciwon sukari suna ɗaukar kayan abinci na zamani na R-lipoic acid kuma suna tabbatar da fa'idodi masu mahimmanci. Slow-saki alpha-lipoic acid Allunan kuma suna taimakawa, wanda ke taimakawa wajen kula da ƙwayar magunguna a cikin jini na dogon lokaci.
- Mafi kyawun kwayoyin Biotin R-Lipoic na Dr;
- R-lipoic acid - karuwar sashi na Tsawan rayuwa;
- Allunan Jarwaƙwalwar rowwayar Jarrow.
-Arin maganin alpha-lipoic acid na Americanan Amurka na ƙarshe shine ainihin madadin waɗanda aka yanke wa waɗanda yawancin masu magana da harshen Rashanci ke fama da ciwon sukari a halin yanzu suna kulawa. Koyaya, tuna cewa abincin low-carbohydrate shine ainihin ingantaccen magani don maganin ciwon sukari da sauran rikitarwa. Duk wasu kwayoyin suna taka rawar sakandare idan aka kwatanta da abinci mai dacewa. Normalize your sugar with a low-carbohydrate rage cin abinci - kuma duk alamun neuropathy za sannu a hankali bace. Ana ba da shawarar cewa alpha lipoic acid na iya hanzarta wannan aikin, amma ba ya maye gurbin abincin.
Yadda za a yi oda alpha lipoic acid daga Amurka akan iHerb - sauke cikakken umarnin a cikin Kalmar ko tsarin PDF. Koyarwa cikin Rashanci.
Don haka, mun gano dalilin da ya sa abincin alpha-lipoic acid na Amurka ya zama mafi inganci da dacewa fiye da magunguna waɗanda zaku iya siyayya a kantin magani. Yanzu bari mu kwatanta farashin.
Jiyya tare da ingantattun magunguna na Amurka na alpha-lipoic acid zai biya ku $ 0.3- $ 0.6 kowace rana, gwargwadon sashi. Babu shakka, wannan ya fi arha fiye da sayen allunan acid na thioctic a cikin kantin magani, kuma tare da raguwa bambanci a farashin gaba ɗaya cosmic ne. Yin odar kayan abinci daga Amurka akan layi na iya zama mafi wahala fiye da zuwa kantin magani, musamman ga tsofaffi. Amma zai biya diyya, saboda zaku sami fa'idodi na ainihi a ƙananan farashin.
Shaida daga likitoci da kuma masu fama da cutar sankara
Teburin da ke ƙasa ya ƙunshi kasidu game da lura da cututtukan cututtukan cututtukan zuciya tare da alpha lipoic acid. Kayan aiki kan wannan batun kai tsaye suna fitowa a cikin littattafan likita. Kuna iya samun masaniya da su dalla-dalla, saboda ƙwararrun ƙwararrun wallafa litattafan labaransu kan yanar gizo kyauta.
No. p / p | Taken labarin | Magazine |
---|---|---|
1 | Alpha-lipoic acid: sakamako mai yawa da ma'ana don amfani da ciwon sukari | Labaran lafiya, A'a 3/2011 |
2 | Masu tsinkaya game da tasirin magani na cututtukan cututtukan ƙwayar cuta na ƙananan ƙarshen tare da alpha lipoic acid | Therapeutic Archive, No. 10/2005 |
3 | Matsayi na damuwa na oxidative a cikin pathogenesis na neuropathy na ciwon sukari da kuma yiwuwar gyarawa tare da shirye-shiryen acid na lipoic acid | Matsalar Endocrinology, A'a. 3/2005 |
4 | Yin amfani da acid na lipoic acid da vitagmal a cikin mata masu ciki tare da nau'in ciwon sukari na I don maganin damuwar oxidative | Journal of Kwayar cuta da Cutar mata, A'a. 4/2010 |
5 | Thioctic (alpha-lipoic) acid - kewayon aikace-aikacen asibiti | Journal of Neurology da ilimin halin dan Adam mai suna bayan S. S. Korsakov, No. 10/2011 |
6 | Sakamakon dogon lokaci bayan 3-mako hanya na ciki na alfa-lipoic acid a cikin ciwon sukari polyneuropathy tare da bayyanar asibiti | Therapeutic Archive, No. 12/2010 |
7 | Sakamakon alpha-lipoic acid da mexidol a kan neuro- da kuma tasiri mai tasiri na marasa lafiya tare da farkon matakan cutar ciwon sukari. | Clinical Medicine, No. 10/2008 |
8 | Clinical da dalilan ƙwaƙwalwar ƙwayar cuta da kuma tasiri na amfani da alpha-lipoic acid a cikin cututtukan gastritis a cikin yara da matasa tare da masu ciwon sukari na sukari | Bulletin na Rashanci na ilimin tsinkaye da ilimin yara, A'a 4/2009 |
Koyaya, sake dubawar likitocin da ke magana da harshen Rashanci game da shirye-shiryen alpha-lipoic acid alal misali ne na ƙauna ta sayarwa da karya. Dukkanin labaran da aka buga tallafin su ne daga masana'antun magunguna ɗaya ko wani magani. Mafi yawan lokuta, ana tallata Berilition, Thioctacid da Thiogamm ta wannan hanyar, amma sauran masana'antun ma suna ƙoƙarin inganta magunguna da kayan abinci.
Babu shakka, likitoci suna da sha'awar rubuta kawai eulogies game da kwayoyi. Dogaro a kansu game da marasa lafiya da ciwon sukari ya kamata ya zama bai wuce ƙa'idodin ƙauna ba, lokacin da suka tabbatar da cewa ba su da lafiya tare da cututtukan da ke ɗaukar jima'i. A cikin sake duba su, likitocin sun nuna matukar damuwa game da tasiri na magungunan da aka sayar a cikin kantin magunguna. Amma idan kun karanta bayanan masu haƙuri, nan da nan za ku ga cewa hoton ba shi da ƙarfin fata.
Binciken da marasa lafiyar da ke magana da ciwon sukari na Rasha game da alpha lipoic acid, wanda za'a iya samu ta yanar gizo, ya tabbatar da haka:
- Kwayoyin hana daukar ciki ba sa taimakawa.
- Droppers tare da thioctic acid haƙiƙa suna inganta ci gaban lafiya a cikin masu ciwon sukari, amma ba daɗewa ba.
- Haske na daji, tatsuniyoyi game da haɗarin wannan magani sun zama ruwan dare a tsakanin marasa lafiya.
Cutar hypoglycemic na iya haɓaka ne kawai idan an riga an kula da haƙuri tare da masu ciwon sukari tare da insulin ko allunan da keɓaɓɓun abubuwan ƙira na sulfonylurea. Haɗin maganin thioctic acid kuma waɗannan wakilai na iya rage yawan sukari jini sosai, har ma zuwa asarar farkawa. Idan kayi nazarin labarinmu game da magunguna masu ciwon sukari na 2 da kuma watsi da kwayoyin cutar da ba su da amfani, to babu abin da zai damu.
Lura cewa babban kayan aiki don ingantaccen magani na neuropathy da sauran rikice-rikice na ciwon sukari shine rage cin abinci mai-carbohydrate. Alpha lipoic acid zai iya inganta shi kawai, yana hanzarta maido da yanayin jijiyoyin al'ada. Amma muddin abincin mai ciwon sukari ya kasance yana cika da carbohydrates, za a sami ma'ana sosai daga shan kayan abinci, ko da a cikin ɗigon ruwa na ciki.
Abin takaici, marasa lafiya marasa magana da Rashanci har yanzu suna da masaniya game da tasiri na rage cin abinci mai ƙirar carbohydrate don nau'in 1 da nau'in ciwon sukari na 2. Wannan juyin juya hali ne na gaske a magani, amma kuma a hankali yana ratsa yawancin marasa lafiya da likitoci. Masu ciwon sukari da ba su da masaniya game da karancin abincin carbohydrate kuma ba sa kiyaye shi sun rasa kyakkyawar damar rayuwa don tsufa ba tare da rikitarwa ba, kamar mutane masu lafiya. Haka kuma, likitoci suna yin tsayayya da canje-canje, domin idan duk masu cutar da masu ciwon sukari na 2 za a kula dasu da kansu, to za a bar endocrinologists ba tare da aiki ba.
Tun daga shekarar 2008, sabon kayan abinci na alfa-lipoic acid suka bayyana a kasashen da ke magana da Ingilishi, wadanda ke dauke da sigar “cigaba” - R-lipoic acid. Wadannan capsules an yi imanin suna da tasiri sosai a cikin cututtukan cututtukan cututtukan daji, masu kama da na gudanarwar jijiyoyin jini. Kuna iya karanta sharhi game da sababbin magunguna a kan rukunin kasashen waje idan kun san Turanci. Babu sake dubawa a cikin Rashanci tukuna, saboda kwanan nan mun fara sanar da masu ciwon sukari na gida game da wannan maganin. R-lipoic acid kari, har da ci gaba mai saki alpha-lipoic acid Allunan, su ne mai kyau wanda zai maye gurbin masu ɗorawa masu tsada mara nauyi.
- Mafi kyawun kwayoyin Biotin R-Lipoic na Dr;
- R-lipoic acid - karuwar sashi na Tsawan rayuwa;
- Allunan Jarwaƙwalwar rowwayar Jarrow.
Muna sake jaddada cewa rage cin abinci a cikin carbohydrate shine babban magani ga masu ciwon suga da sauran rikice-rikice, kuma alpha lipoic acid da sauran kari suna taka rawa ta sakandare. Muna samar da duk bayanai game da abincin low-carbohydrate don nau'in 1 da nau'in ciwon sukari na 2 kyauta.
Karshe
Alpha lipoic acid na iya zama babbar fa'ida a cikin rigakafi da lura da ciwon sukari. Yana da tasirin warkewa lokaci guda a hanyoyi da dama:
- Yana kare cututtukan beta na pancreatic, yana hana lalacewarsu, watau, kawar da dalilin cutar sankara 1.
- Yana haɓaka ƙwayar glucose nama a cikin nau'in 2 na ciwon sukari, yana ƙaruwa da hankalin insulin.
- Yana aiki azaman antioxidant, wanda yake mahimmanci musamman don rage ci gaban cututtukan cututtukan cututtukan zuciya, kuma yana kula da matakan al'ada na ƙwayoyin ciki na ciki na C.
Gudanar da maganin alpha-lipoic acid ta amfani da masu ɗorewa na cikin jiki yana ƙara haɓaka insulin a cikin marasa lafiya masu fama da ciwon sukari na 2. A lokaci guda, nazarin asibitoci da aka gudanar kafin 2007 ya nuna cewa shan wannan kwayar cutar ta antioxidant ba ta da tasiri. Wannan mai yiwuwa ne saboda Allunan ba za su iya kula da maida hankali kan magani a cikin jini ba har tsawon lokaci. An warware wannan matsalar ta hanyar haɗuwa da sabbin magungunan R-lipoic acid, wanda ya haɗa da Bio-Enhanced® R-Lipoic Acid, wanda GeroNova ke ƙirƙira shi kuma yana siyarwa kuma ana siyar dashi a Rana ta Mafi Kyawun Likita da Rayuwa Mai Ruwa. Hakanan zaka iya gwada maganin alpha lipoic acid a cikin Jarrow Formulas an ci gaba da allunan sakin.
- Mafi kyawun kwayoyin Biotin R-Lipoic na Dr;
- R-lipoic acid - karuwar sashi na Tsawan rayuwa;
- Allunan Jarwaƙwalwar rowwayar Jarrow.
Har yanzu, muna tunatar da ku cewa babban magani ga masu ciwon sukari ba kwayoyin hana haihuwa bane, ganye, addu'o'i, da dai sauransu, amma da farko shine rage cin abinci mai-carbohydrate. Yi nazari a hankali kuma ka bi tsarin shirin 1 na maganin cututtukan ƙwaƙwalwar mu ko shirin kula da masu ciwon sukari na 2. Idan kuna damuwa da ciwon sukari mai cutar ciwon sukari, to za ku ji daɗin sanin cewa cuta ce da za ta iya canzawa gaba ɗaya. Bayan kun daidaita sukari na jini tare da rage cin abinci mai-carbohydrate, duk alamomin neuropathy zai tafi daga 'yan watanni zuwa shekaru 3. Wataƙila shan alpha lipoic acid zai taimaka saurin wannan. Koyaya, kashi 80-90% na magani shine abincin da ya dace, kuma duk sauran magunguna kawai suna dace da shi. Kwayoyin kwayoyi da sauran ayyukan zasu iya taimakawa sosai bayan kun cire carbohydrates mai yawa daga abincinku.