Glidiab wani magani ne da ake nemansa da yawa wanda aikinsa da nufin inganta yanayin marasa lafiya tare da kamuwa da cutar sukari na 2. Abubuwan da ke aiki na abun da ke ciki suna taimakawa rage yawan glucose da kuma tabbatar da sarrafa glycemic.
Sunan kasa da kasa mai zaman kansa
INN Gliclazide (gliclazide).
A cikin Latin - Glidiab.
Wasanni
A cikin lissafin atomic-warkewa-sunadarai, an sanya magungunan lambar A10BB09.
Glidiab wani magani ne da ake nemansa da yawa wanda aikinsa da nufin inganta yanayin marasa lafiya tare da kamuwa da cutar sukari na 2.
Saki siffofin da abun da ke ciki
Ana samun Glidiab a cikin nau'ikan allunan da ke da nau'i mai zagaye da kirim mai tsami (ko ɗan rawaya kaɗan). Kunshin ya ƙunshi allunan 60.
Babban sashi mai aiki a cikin abun da ke ciki shine gliclazide. Volumeararsa a cikin kowane kwamfutar hannu ya kai 80 MG.
Glidiab MV ya ƙunshi 30 MG na abu mai aiki.
Abubuwan da ke cikin taimakon abubuwan sun hada da: magnesium stearate, sukari madara, talc, hypromellose, glycolate sitaci, MCC.
Glidiab yana samuwa a cikin nau'ikan allunan da aka zagaye da siffar.
Aikin magunguna
Allunan magani ne na ƙungiyar masu haɓaka haɓaka haɓaka. Tasirin magungunan an yi shi ne da nufin daidaita matakai da yawa:
- Kwayoyin Pancreatic B suna fara aiki da insulin aiki sosai;
- Kwayoyin na gefe suna karuwa da haɓakar hankali ga insulin;
- aikin glucose ya sami kayan aikin insulin wanda aka inganta;
- tazara daga lokacin cin abinci har zuwa farkon fitar insulin.
- reducedara yawan postprandial a matakan glucose ya ragu;
- farkon farfadowa daga samar da insulin.
Maganin yana da tasiri mai kyau akan microcirculation:
- vascular permeability an dawo dasu;
- tarawar platelet da adhesion suna raguwa;
- fibrinolysis na physiological parietal al'ada ne;
- haɗarin haɓakar atherosclerosis da microthrombosis an rage su;
- yana rage yawan hankalin masu karɓar bugun jini zuwa ga adrenaline.
A peculiarity wannan magani shi ne cewa kai tsaye rinjayar farkon matakin insulin insulin. Wannan halayyar ta bambanta ta da sauran hanyoyi, kamar yadda marasa lafiya ba sa ƙaruwa da nauyin jiki. Karkashin maganin warkewa wanda likitan ya ba da shawarar, waɗancan marasa lafiyar da suka wuce kiba suna iya dawo da lafiyar jiki daidai.
Pharmacokinetics
Bayan shan magungunan, matsakaicin matakin sashi na aiki a cikin jini yana isa bayan awa 4. A cikin hanta, biotransformation na metabolites yana faruwa: suna oxidized, akwai aiki glucuronidation da hydroxylation. Sakamakon tsari, an kirkiro metabolites 8 waɗanda ba su cikin glucose.
An cire kayan daga jikin ta cikin kodan (kusan kashi 70%) kuma ta cikin hanji (kusan 12%). Cire rabin rayuwa yana sanya awa 8-11.
Alamu don amfani
An tsara wannan magani ga marasa lafiya da nau'in ciwon sukari na 2 na matsanancin rauni. Ya dace lokacin da rikitarwa ya bayyana (microangiopathy). A cikin waɗannan halayen, ana iya amfani da maganin azaman monotherapy ko azaman magani mai wahala tare da magungunan hypoglycemic.
An tsara wannan magani ga marasa lafiya da nau'in ciwon sukari na 2 na matsanancin rauni.
A matsayin prophylactic, ana ba da shawarar allunan don toshe ci gaban cututtukan cututtukan cututtukan jini a cikin ciwon sukari.
Contraindications
Jerin contraindications ga wannan magani ya haɗa da cututtukan da ke biyo baya da cututtuka:
- nau'in ciwon sukari na 1;
- labile na nau'in ciwon sukari na 2;
- kasancewar insuloma a cikin mara lafiya;
- ketoacidosis;
- na koda da kuma hanta gazawar;
- mummunan microangiopathy;
- rashin ƙarfi ga sulfonylurea;
- ciki da lactation;
- cututtuka;
- lokacin ayyukan tiyata kafin da bayansu (48 hours);
- yara ‘yan kasa da shekara 18.
Tare da kulawa
Dangane da umarnin, akwai wasu cututtuka da yanayi wanda takardar sayan magani ya buƙaci daidaita sashi da mita na gudanarwa. Wannan shi ne:
- ilimin cututtukan thyroid;
- zazzabi
- shan barasa (giya);
- kasa aiki adrenal gland shine yake;
- gabancin cutar sankara mai rashin lafiya.
A gaban ɗaya ko fiye na abubuwan da aka ambata a sama, likita ya kamata ya zaɓi hanya na kiwon lafiya daban-daban. Ana ganin yiwuwar daidaita Glidiab.
Yadda ake ɗaukar Glidiab
Don saukakawa, al'ada ce a rarrabe magungunan yau da kullun:
- daidaitattun - 80 MG / rana .;
- matsakaici - 160 MG / rana .;
- matsakaicin shine 320 MG / rana.
An kasu kashi na yau da kullun zuwa kashi biyu daidai kuma ana ɗauka da safe da maraice mintuna 30 kafin abinci. Sha maganin tare da ruwa mai yawa.
Shan maganin don ciwon sukari
Ba'a ba da shawarar shiga cikin maganin kai ba, tunda an haramta maganin don nau'in cutar sukari na 1 da nau'in 2 don haɓaka labile. Kafin rubuta magani, likita yayi nazarin shekarun mai haƙuri, matakin cutar, alamomin glycemia, da kuma yiwuwar amfani da wasu kwayoyi.
Kafin rubuta magani, likita yayi nazarin shekarun mai haƙuri, matakin cutar, alamomin glycemia, da kuma yiwuwar amfani da wasu kwayoyi.
Sakamakon sakamako na Glidaba
Sakamakon sakamako daga shan magani yana da ɗan wuya. A mafi yawan lokuta, allunan suna jurewa da kyau.
Marasa lafiya na iya yin gunaguni na:
- Dizziness
- ciwon kai
- gajiya;
- halayen rashin lafiyan (itching da urticaria);
- haɓakar ƙwayar disulfiram-kamar ciwo (tashin zuciya, zawo, ko maƙarƙashiya);
- asthenia;
- daukar hoto.
Kadan an lura sosai:
- paresis;
- hypoglycemia;
- thrombocytopenia;
- agranclocytosis;
- leukopenia;
- anemia
Tasiri kan ikon sarrafa abubuwan inji
Lokacin shan wannan magani, ya kamata marasa lafiya su yi hankali don tuki, sarrafa injin, da kuma shiga cikin wasanni masu haɗari.
Umarni na musamman
Don rage haɗarin sakamako masu illa, yakamata a tsaida miyagun ƙwayoyi don cin abinci. Mahimman bukatun sune rashin matsananciyar yunwa da kuma cikakken kewar giya.
Ana aiwatar da hanya ta hanyar haɗuwa tare da abinci mai ɗauke da ƙananan adadin carbohydrates. A lokaci guda, kuna buƙatar kulawa da abun ciki na glucose a cikin jini koyaushe a cikin komai a ciki da kuma bayan cin abinci.
Don rage haɗarin sakamako masu illa, yakamata a tsaida miyagun ƙwayoyi don cin abinci.
A cikin yanayin inda mai haƙuri yana da matsanancin motsa rai ko damuwa na jiki, sashi na miyagun ƙwayoyi ya kamata a daidaita shi.
Yi amfani da lokacin daukar ciki da lactation
Ba a sanya magani ba.
Adanar Glidiab ga Yara
Sakamakon cewa babu bayanai game da haɗari da fa'idodi na magani ga yara, ba a ba da umarnin ga marasa lafiya waɗanda shekarunsu ba su wuce 18 ba.
Yi amfani da tsufa
Tsofaffi marasa lafiya ba sa buƙatar gyaran sashi. Banda sune wadancan mutanen da ke da cututtukan da ke bukatar kara kulawa.
Tsofaffi marasa lafiya ba sa buƙatar gyaran sashi.
Yawan abin shafawa na Glidab
Wucewa wadannan hanyoyin warkewa yana haifar da raguwar yawan sukari cikin jini. Irin waɗannan canje-canjen na iya haifar da cutar rashin ruwa na hypoglycemic coma, ciwon suga.
Matsakaici yana raguwa ga gabatarwar glucose, sucrose ko dextrose a cikin jiki. Akwai hanyoyi da yawa don yin wannan:
- a baki (idan mutum zai iya hadiye shi);
- cikin jijiyoyin ciki (idan mai haƙuri bai sane ba) - Ana gudanar da maganin 40% na dextrose.
Bugu da ƙari, 1-2 mg na glucagon ana gudanar dashi intramuscularly. Bayan mutum ya sake samun nutsuwa, ana nuna shi yana cin abinci mai narkewa cikin sauki.
Wucewa wadannan hanyoyin warkewa yana haifar da raguwar yawan sukari cikin jini.
Yin hulɗa tare da wasu kwayoyi
Don zaɓar sashi, dole ne a la'akari da dacewa da miyagun ƙwayoyi tare da wasu kwayoyi amfani da magani.
Wannan magani bai dace da shirye-shiryen miconazole ba.
Ayyukan gliclazide mai aiki yana haɓaka ta hanyar magungunan masu zuwa:
- fibrates;
- ACE masu hanawa;
- beta-blockers;
- biguanides (metformin);
- magungunan anabolic steroids;
- salicylates;
- MAO masu hanawa;
- hanyoyin tetracyclines;
- maganin rigakafi
- phosphamides;
- coumarins.
Tasirin miyagun ƙwayoyi ya raunana ta kwayoyi masu zuwa daga cikin jerin:
- glucocorticoids;
- barbiturates;
- m
- kwayoyin hodar iblis;
- salama;
- salts na lithium;
- Rifampicin;
- Chlorpromazine;
- Glucagon.
Babban allurai na estrogen, maganin hana haihuwa, nicotinic acid na iya raunana sakamako.
Amfani da barasa
Yayin magani tare da Glidiab, yakamata a bar giya gaba daya. Idan aka haɗu, ingancin maganin yana da ƙasa. Bugu da kari, kasancewar ethanol yana kara hadarin sakamako masu illa.
Analogs
Magungunan asali na wannan rukunin sune Gliclazide (yana ƙunshe da kayan aiki mai sunan guda ɗaya). Duk sauran magunguna tare da wannan abun ana ɗaukarsu kwayoyin halitta ne. Ana amfani da magungunan masu zuwa ga wakilan maganin maganin ƙwayoyin cuta wanda ke ɗauke da gliclazide:
- Diatics;
- Diagnizide;
- Diabefarm;
- Diabinax;
- Yarda;
- Diabresid;
- Gliklada;
- Diabetalong;
- Glucose;
- Yarda;
- Glioral;
- Diabresid;
- Glucostabil;
- Medoclazide.
Akwai magunguna da yawa waɗanda suka zo daidai da manufa (nau'in ciwon sukari na 2). Daga cikinsu akwai kadan daga cikin wadanda ake nema:
- Januvius;
- Glucobay;
- Bagomet;
- Baeta;
- Lymphomyozot;
- Avandiya
- Methamine;
- Multisorb;
- Kayan tsari.
Magunguna kan bar sharuɗan
Zaka iya siyan wannan magani a cikin kantin magani kawai kawai takardar sayan magani.
Farashin Glidiab
Kudin maganin yana bambanta dan kadan dangane da farashin farashin kantin magani. A cikin Moscow, farashin ya tashi daga 120 zuwa 160 rubles.
Zaka iya siyan wannan magani a cikin kantin magani kawai kawai takardar sayan magani.
Yanayin ajiya na miyagun ƙwayoyi
An sanya maganin a matsayin B. Ya kamata a adana shi a cikin duhu daga nesa da yara a zazzabi da bai wuce + 25 ° C ba.
Ranar karewa
Adadin ajiya shine shekaru 4. Bayan wannan lokacin, an haramta shan maganin.
Mai masana'anta
Kamfanin da kamfanin ke yin kayayyakin shine kamfanin Russia na Akhirin Chemical Farm OJSC. Ofishin kamfanin da kuma samarwarsa suna cikin yankin Moscow, kauyen Staraya Kupavna.
Glidiab sake dubawa
Irina, ɗan shekara 49, Tyumen
Na ɗan sha Glidiab tsawon shekara ɗaya yanzu, halin da nake ciki ya zama ingantacce. M: kuna shan kwaya da safe kuma kuna iya zuwa aiki lafiya kuma kar ku damu da sukari. Abinda bai kamata a manta da shi ba shine maganin warkewa. In ba haka ba, maganin ya kusan zama mara amfani.
Natalia, shekara 35, Izhevsk
Na ɗanɗana wani lokacin kuma na sha wani magani mai kama da wannan. Bayan 'yan watanni da suka gabata, likita ya koma Glidiab. Da farko, ya haifar da rashin jin daɗi a cikin ciki. Bayan wasu 'yan makonni, illolin cutar sun lalace. Na ci gaba da shan magungunan. Ya zuwa yanzu, komai yayi kyau.
