Ana amfani da inhibitors na ACE don hauhawar jini, gazawar zuciya da kuma rigakafin cututtukan cututtukan zuciya. Magunguna kamar enalapril ko captopril suna hana sinadarai wanda ke inganta vasoconstriction da haɓaka matsin lamba. Ana amfani dasu azaman kayan aiki mai zaman kansa don daidaita jinin jini, kazalika a cikin haɗin gwiwa tare da wasu magunguna.
Halayen Enalapril
Enalapril yana rage karfin jini, nauyin a kan myocardium, yana ba da izinin numfashi da zagayawa cikin jini a cikin karamin da'ira, yana haɓaka jini sosai cikin tasoshin kodan.
Enalapril ko Captopril yana hana sinadaran da ke inganta vasoconstriction da haɓaka matsin lamba
Babban sinadaran aiki shine enalapril, wanda, bayan sha, yana da ruwa sosai ga enalaprilat, mai hana ACE, peptide dipeptidase wanda ke haɓaka juyar da angiotensin. Godiya ga toshewar ACE, ƙirƙirar abubuwan vasoconstrictor an rage shi kuma an samar da haɗin dangi da prostacyclin, waɗanda ke da vasodilating dukiya, suna aiki. Enalapril yana da tasirin diuretic wanda ke da alaƙa da ɓoyewar ƙirar aldosterone.
Decreasearancin raguwa a cikin ayyukan ACE yana faruwa awanni 3 bayan shan miyagun ƙwayoyi, ana lura da ganiya a cikin saukar karfin jini bayan sa'o'i 5. Tsawancin sakamakon yana da alaƙa tare da sashi, a mafi yawan lokuta tasirin maganin yana ci gaba cikin kullun. Wasu marasa lafiya suna buƙatar makonni da yawa na jiyya don cimma daidaitaccen karfin jini.
Bayan an shiga jiki, an sha magani cikin hanzari a cikin hanji, bayan wannan abu yana sanya ruwa cikin jiki ya zama enalaprilat, wanda kodan ya fi karba, haka kuma ta cikin hanji.
Alamu don amfani:
- hauhawar jini;
- babban rauni na zuciya;
- cututtukan zuciya da na jijiyoyin jini;
- yanayi na zuciya;
- rigakafin ci gaban ciwan zuciya mai rauni.
Enalapril yana rage karfin jini da inganta haɓakar jini a cikin tasoshin kodan.
Yardajewa:
- rashin haƙuri a cikin abubuwan da ke cikin miyagun ƙwayoyi;
- ciki, lokacin shayarwa;
- stenosis na aortic orifice;
- na koda na fitsari;
- bayan sakewan koda;
- hyperkalemia
- haɗin gwiwa tare da Aliskiren a cikin marasa lafiya tare da ciwon sukari mellitus, aiki mai rauni na koda.
Ba a wajabta magunguna ga yara 'yan ƙasa da shekaru 18 ba.
A lokacin maganin enalapril, jijiyoyin tsoka, tashin zuciya, ciwon kai, zawo, halayen fata na rashin lafiyar jiki, orthostatic hypotension zai yiwu.
Ana shan maganin a baka, ba tare da la'akari da abincin ba.
Tare da hauhawar jini, daidaitaccen matakin guda ɗaya na manya shine 0.01-0.02 g in s
ducks. Matsakaicin na yau da kullun shine 0.04 g .. Mafi kyawun maganin za a iya zaɓar ta likita mai halarta daban-daban ga kowane mara lafiya. Tsawon lokacin karatun warkewa ya dogara da tasirin magani.
Halayen Kafa
ACE inhibitor yana rage karfin jini kuma ana amfani dashi don hauhawar jini, nephropathy, ciwon sukari etiology, gazawar zuciya. Yana da tasirin vasodilating, yana haɓaka fitowar zuciya da juriya ga damuwa, ba tare da cutar metabolism na lipid ba.
Babban kayan aiki shine captopril, wanda shine farkon roba ACE mai hanawa a cikin aikin likita. Yana toshe chanji na angiotensin I zuwa angiotensin II, yana taimakawa rage karfin jini, rage girman tashin jijiyoyin jini na hagu, yana hana haɓakar bugun zuciya, da inganta haɓakar hemodynamics a cikin kodan, da kuma hana haɓakar cutar sankarar hanta.
Captopril yana dafe cikin hanzari, yana daidaita shi a cikin hanta, an keɓe shi zuwa mafi girma daga kodan. Rabin rayuwar kusan minti 120 ne.
Ana yin rikodin mafi girman sakamako bayan sa'o'i 1-1.5. Tsawon lokacin aikin ya dogara da yawan ƙwayoyi.
Captopril shine bu mai kyau ga irin waɗannan cututtukan:
- hauhawar jini;
- bugun zuciya;
- karancin lalacewa;
- mai ciwon sukari nephropathy.
Babban kayan aiki shine captopril, wanda shine farkon roba ACE mai hanawa a cikin aikin likita.
Ana amfani da miyagun ƙwayoyi don hana gazawar cututtukan zuciya a cikin marasa lafiya da asymptomatic hagu ventricular dysfunction a cikin yanayin kwanciyar hankali na asibiti.
Yardajewa:
- hypersensitivity ga abubuwan da ke cikin miyagun ƙwayoyi;
- mummunan cutar koda;
- hyperkalemia
- na koda na fitsari;
- stenosis na aortic orifice da sauran canje-canje da suka karya zubar da jini na al'ada daga ventricle hagu;
- yanayin bayan sakewar koda;
- 2 da 3 watanni uku na ciki;
- lokacin shayarwa.
Ba a tsara wa yara underan ƙasa da shekara 14 ba.
Allergic rashes, canjin canji, rashin ƙarfi, leukopenia, proteinuria, agranulocytosis, rashi, rashin daidaituwa na motsi mai yiwuwa azaman sakamako masu illa yayin ɗaukar ƙwayoyi.
Mafi kyawun kashi na Captopril an kafa shi ne ta ƙwararrun masani daban kuma ya bambanta daga 0.025 g zuwa 0.15 g kowace rana. Game da haɓakawa mai sauri da haɓaka a cikin karfin jini, ana bada shawara don ɗaukar mafi ƙarancin kashi, yana ɗaukar kwamfutar hannu a ƙarƙashin harshe. A cikin lura da yara, mafi kyawun kashi ana lasafta yana la'akari da nauyin jikin mutum, yawanci shawarar shine 0.001-0,002 g da 1 kg.
Kwatanta Miyagun Kwayoyi
Kama
Magungunan suna cikin rukuni na ACE inhibitor, suna da irin wannan hanyar aiki kuma ana amfani dasu don magance cutar hawan jini, cututtuka na tsarin zuciya. Suna da kusan iri ɗaya contraindications. Tasirin warkewa shine maganin dogaro.
Mene ne bambanci
Babban bambanci shine a cikin abun da ke ciki. Dukkanin magungunan an samo asali ne daga tsararren amino acid wanda aka samo asali. Amma enalapril ya bambanta da yanayin kwatankwacinsa a hadadden tsarin kemikal ɗin: lokacin da ya shiga jiki, babban abu mai aiki yana ɗaukar ruwa zuwa enalaprilat, wanda ke hana ACE.
Magungunan sun sha banban da shawarar da aka ba da shawarar gudanarwa. Tare da hauhawar jini, ana daukar enalapril sau 1 a rana. Captopril yana da sakamako mai ƙarewa, don kiyayewa wanda ya wajaba don shan miyagun ƙwayoyi sau da yawa a rana.
Captopril ya fi kyau tare da diuretics. Lokacin da ake bi da shi tare da analog ɗin shi, ana bada shawara don rage yawan magungunan diuretic ko watsi da su na ɗan lokaci.
Wanne ne mai rahusa
Magunguna suna da ƙananan farashi kuma suna samuwa ga masu amfani. Matsakaicin matsakaici shine 60-130 rubles.
Menene mafi kyawu enalapril ko captopril
Enalapril ya dace sosai don tsawan amfani idan ya cancanta don kula da karfin jini a cikin kewayon da ake so, amma ba a amfani dashi azaman motar asibiti. Captopril yana da tasiri don daidaitawa na aiki na episodic na ƙara yawan matsa lamba. Har ila yau, maganin yana da tasiri mai amfani ga aikin zuciya, yana ƙara ƙarfin hali tare da ɗauka na yau da kullun, wanda ya sa yin amfani da shi ya dace a gaban cututtukan cututtukan zuciya.
Yadda za a canza daga captopril zuwa enalapril
Magungunan suna cikin rukunin magunguna iri ɗaya kuma ana alaƙar su da ma'amala mara ma'ana, wanda ke da haɗari ga lafiya kuma yana iya haifar da raguwa sosai a cikin hawan jini. A cikin lura da hauhawar jini, ana amfani da kwayoyi daban-daban. Don canzawa daga wannan magani zuwa wani, kuna buƙatar tuntuɓi ƙwararrun masani waɗanda zasu zaɓa mafi kyawun kashi, nau'in fitarwa da tsarin kulawa da la'akari da tarihin likita, shekaru da sauran halayen mutum na mai haƙuri.
Neman Masu haƙuri
Marianna P. "Daga lokaci zuwa lokaci matsin lamba yakan tashi, amma na yi ƙoƙarin gujewa shan magunguna don rage nauyin magunguna. A shekara daya da ta gabata na kasance a asibiti sakamakon tafiye-tafiye da akai-akai da canjin yanayi .. Hadaddun matakai na likita ba zai iya kawar da matsanancin ba, har ma allurar ba ta inganta yanayin sosai "Na tuna cewa da zarar abokina ya ba da shawarar Captopril. Na sa allunan 2 a karkashin harshen na, kuma bayan mintuna 30 matsin lamba ya fara raguwa. Kashegari ya koma gaba ɗaya. Yanzu koyaushe koyaushe ina sa wannan maganin a cikin jakata."
Vika A: "Ban dauki Captopril a matsayin motar asibiti ba. Mamar suruwar matar suruka tayi tsalle sosai, ta sanya 2 a karkashin harshenta, 3 da 'yan' yan sa'o'i kadan bayan haka, kusa da safiya sake 2. Kuma kawai da safe bai canza kyau ba. a rage. Idan an sanya magani a matsayin motar asibiti, to yakamata a yi amfani da miyagun ƙwayoyi cikin sauri. Matsin lambar suruka ta dawo ta al'ada ne kawai bayan da likitan ya shigar da wasu miyagun ƙwayoyi tare da maganin diuretic. "
Elena R. "Lokacin da aka fitar da shi daga asibiti, an sanya mahaifiyar Enalapril. Nan da nan ta lura da tari wanda ba ta kasance a can. Na karanta umarnin don miyagun ƙwayoyi, ya zama cewa ba ya aiki ga kowa. Ya kamata a sha shi da hankali, amma ya fi kyau a sami wanda zai musanya shi."
Magungunan sun sha banban da shawarar da aka ba da shawarar gudanarwa.
Likitoci sun bita da enalapril da captopril
Tsukanova A. A., mai ilimin hanyoyin kwantar da hankali tare da shekaru 5 na kwarewa: "Amfanin kawai na Enalapril shine farashi mai araha. Ba shi da amfani a cikin ƙananan allurai, yawancin yana sha shi gwargwadon ƙaddara mai yarda. Yana yawan haifar da mummunan sakamako a cikin yanayin busassun tari, don haka bai dace da asthmatics ba. Ina ba da shawarar wannan magani ga marasa lafiya, akwai magunguna masu inganci da na zamani. ”
Zafiraki V.K., likitan zuciya tare da shekaru 17 na kwarewa, Ph.D. abu ne, amma kamfani na farko da kamfanin da ya kera shi ya kirkiro shi, na biyu kuma kwafin na asali ne wanda aka kirkira shi kuma kamfanoni daban-daban ne ke samarwa. Ina ba da shawarar siyan magungunan biyu da kwatanta wanne yafi karfi. "
