Lorista 12.5 magani ne na zuciya wanda ke rage karfin jini, ba tare da la'akari da jinsi da shekarun marasa lafiya ba. Yana aiki ta hanyar toshewar angiotensin hormone oligopeptide, wanda ke haifar da vasoconstriction.
Sunan kasa da kasa mai zaman kansa
Losartan.
ATX
Lambar ATX ita ce C09CA01.
Lorista 12.5 magani ne na zuciya wanda ke rage karfin jini, ba tare da la'akari da jinsi da shekarun marasa lafiya ba.
Saki siffofin da abun da ke ciki
An samar dashi ne da nau'ikan allunan da aka shirya fim wadanda ke dauke da abubuwa masu aiki da kayan taimako a cikin kayan sa.
Kunshin na iya dauke da allunan 30, 60 ko 90 a cikin blister of 10 guda. Akwai sashi na 12.5 MG, 25 MG, 50 MG da 100 MG.
Lorista 12.5 ya ƙunshi 12.5 mg na abu mai aiki.
Abunda yake aiki shine potassium losartan.
Abubuwan da ya samo asali na lactose don latsawa kai tsaye an haɗu da su tare da taurari, enterosorbent, thickener, da sauransu Abun ciki ya haɗa da kayan aikin fim ɗin samfurin.
Aikin magunguna
Losartan mai adawa ne na angiotensin 2. Yana toshe masu karban wannan kwayar cutar ta musamman a cikin jijiyoyin jini na zuciya, kodan da adrenal gland, don haka yana haifar da tasirin sakamako.
Yana rage juriya a tasoshin kewaye, matsa lamba a cikin jijiyoyin huhun ciki; yana da tasirin diuretic, yana kara juriya ga aikin jiki a cikin raunin zuciya.
A cikin marasa lafiya tare da hauhawar jijiyoyin jini, losartan a cikin shawarar da aka ba da shawarar ba ya shafar adadin azumi triglycerides, ƙwaƙwalwar cholesterol, matakin glucose.
Ana amfani da miyagun ƙwayoyi a cikin nau'i na allunan a cikin kwasfa na fim, wanda ke ƙunshe a cikin kayan aikinsa da kuma tsofaffi.
Pharmacokinetics
Kasancewa cikin abu mai aiki yana faruwa da sauri kuma bayan minti 60-70 mafi girman maida hankali ga jini plasma kuma raguwar angiotensin an riga an cimma. Yana yadawa ta hanyar daurawa garkuwar jini na jini. An canza shi a cikin hanta zuwa carbonxylic acid.
Nishadi yakan faru ne tsakanin awanni 6 zuwa 9 ta hanjin kodan tare da fitsari kuma ta cikin hanji da bile.
Abinda ya taimaka
Wannan magani ne mai inganci don haɗakarwa da jijiyoyin jini da tashin zuciya.
An nada a cikin wadannan lamura:
- hawan jini na farko a cikin girma;
- a cikin lura da cutar koda a cikin tsofaffi marasa lafiya tare da hauhawar jini da kuma nau'in ciwon sukari na 2 na sukari da proteinuria;
- wani nau'in rashin lafiyan bugun zuciya, lokacin da ba zai yiwu a yi amfani da takamaiman wakilai ba saboda rashin haƙuri;
- rigakafin bugun jini tare da hauhawar jini da tabbatar da hauhawar jini ventricular hagu.
A wani matsin lamba don ɗauka
An wajabta shi lokacin da hauhawar jini ke ƙaruwa, ba tare da la'akari da shekaru ba, ban da yara 'yan ƙasa da shekaru 6.
Contraindications
Kayan kai tsaye sune:
- karancin jini;
- mummunar amsawa ga abu mai aiki ko wasu abubuwan da ke cikin miyagun ƙwayoyi;
- shekaru har zuwa shekaru 6;
- ƙara yawan ƙwayoyin jini a cikin marasa lafiya;
- matsanancin ƙwayar glucose;
- rashin daidaituwa tsakanin lactose;
- rashin ruwa a jiki;
- lokacin haihuwa da shayarwa.
Tare da kulawa
Ya kamata a kula da kulawa ta musamman yayin rubuta magunguna ga yara da matasa masu shekaru 18 saboda ƙarancin ilimin tasirin da ke tattare da jikin yaran da ci gabanta.
A hankali kuma a karkashin kulawar ma’aikatan asibiti, ana karbar kudi yayin takaitaccen kwararan hanji, bayan jujjuyawar koda, yayin kunkuntar aorta ko mitral valve, toshewar bango na hagu ko dama, zuciya, gurgunta ayyukan koda a cikin gazawar zuciya, cututtukan zuciya, cututtukan tasoshin jini na kwakwalwa, karuwar samar da aldosterone, shan allurai da yawa na magungunan diuretic.
Yadda ake ɗaukar Lorista 12.5
Oauki baki sau ɗaya a rana, ba a mai da hankali kan cin abinci ba (a gabanin, bayan, lokacin cin abincin).
Gudanarwa mai yiwuwa a haɗuwa tare da sauran magungunan antihypertensive.
Tare da cutar hawan jini, an fara yin allurar 50 a farko, sannan, a cewar wasu masu cutar, an kara adadin zuwa 100 MG kowace rana.
A cikin cututtukan hanta, ya danganta da tsananin ƙarfin su da kuma hanya, yawan lokuta magani yana rage zuwa 25 MG kowace rana.
A cikin rauni na zuciya, da farko ba 12.5 MG kowace rana, sannan sannu a hankali ƙara zuwa 150 MG kowace rana, kowane lokaci yana ƙaruwa da kashi sau biyu tare da tazara tsakanin mako guda. Ana ba da shawarar yin wannan irin tsarin gudanarwa a hade tare da diuretics da glycosides na zuciya.
Oauki baki sau ɗaya a rana, ba a mai da hankali kan cin abinci ba (a gabanin, bayan, lokacin cin abincin).
Tare da ciwon sukari
Idan mai haƙuri yana da ciwon sukari na mellitus na digiri na biyu tare da haɓakar furotin a cikin fitsari, don hana buƙatar dialysis da sakamako mai kisa, farkon maganin zai zama al'ada 50 mg tare da karuwa a nan gaba har zuwa 100 MG a kowace rana, dangane da sakamako akan rage karfin jini. Amincewa da insulin da kwayoyi waɗanda suke rage matakin sukari (glitazone, da sauransu). An ba shi izinin ɗaukar diuretics da sauran magungunan antihypertensive.
Side effects
Smallarancin adadin sakamako masu illa yana da asali a cikin magani, amma akwai maganganun da ke cikin raunin rashin isasshen amsawar jiki daga ɓangarori da tsarin daban-daban. Don haka, tsarin zuciya zai iya amsawa tare da kara karfin zuciya, bugun zuciya, da sauransu.
Matsalar hanci, kumburi da ƙwanƙolin ciki, ƙwanƙwasawa, jin zafi na baya, wata gabar jiki da tsokoki, da kuma keta daidaituwar ƙwaƙwalwar ruwa. Amma galibi, halayen suna da rauni da kuma jinkirin da za a canza canji ko kuma canjin magani.
Gastrointestinal fili
Tsarin narkewa na iya amsawa ga kasancewar losartan ta hanyar tashin zuciya, matattarar damuwa, dyspepsia, da zafin ciki.
Hematopoietic gabobin
Da wuya, amma ana iya samun bayyanuwa ta hanyar anemia da purpura na Shenlein-Genoch.
Tsarin juyayi na tsakiya
Gefen da tsarin juyayi na tsakiya na iya samun irin wannan sakamako kamar suwar ciki, rauni gaba ɗaya, ciwon kai, gajiya, hargitsi na bacci.
Cutar Al'aura
An rikodin maganganun da keɓaɓɓiyar halayen anaphylactic da halayen ƙwayar cuta na gida.
Tasiri kan ikon sarrafa abubuwan inji
Lokacin sarrafa hanyoyin da yayin tuki, ana buƙatar taka tsantsan, kamar yadda tsananin damuwa da nutsuwa mai yiwuwa ne. Irin wannan halayen shine halayyar matakan farko na magani ko tare da babban kashi.
Umarni na musamman
Marasa lafiya waɗanda suka taɓa fuskantar edema, hanta ko cutar koda ya kamata su sami magani tare da magani kawai a ƙarƙashin kulawar likita da dalilai na kiwon lafiya.
Kada a yi amfani da maganin ta hanyar haƙuri tare da aliskiren ko aliskiren da ke ƙunshe da magunguna don ciwon sukari.
Yi amfani da tsufa
A cikin tsufa, sashi ba ya bambanta da samari.
Yi amfani da lokacin daukar ciki da lactation
Lokacin haihuwar da shayarwa, ba a sanya magani ba, kuma idan aka tabbatar da juna biyu, an soke shi nan da nan, tunda akwai hadari ga tayin (hypoplasia na huhu da kwanyar, lalata nakasa, kwarangwal koda na tayin, da dai sauransu). Ba a yi nazarin tasirin jarirai na maganin ba a madarar nono, saboda haka, bai kamata a yi amfani da shi ba saboda rashin tabbas game da halayen jikin yaron.
Yayin shayarwa, ba a sanya magani ba.
Alkawarin Lorista yara 12.5
Ba a ba da umarnin ƙananan yara 'yan ƙasa da shekara shida. A lokacin tsufa kuma har zuwa shekaru 18, ba a bayar da shawarar amfani da shi ba kuma yana yiwuwa ne kawai in babu wani madadin, tunda babu karatu a cikin ilimin yara game da amfani da kwayoyi tare da losartan a cikin abun da ke ciki.
Yawan damuwa
A cikin batun yayin da aka ɗauki ƙwaƙƙwaran ƙarfin ƙwayar cuta mai ƙarfi, yanayin jijiyoyin jini da ajiyar zuciya na iya faruwa, waɗanda aka kawar da su akan alamu.
Yin hulɗa tare da wasu kwayoyi
Yana da daidaituwa mai kyau tare da hydrochlorothiazide, digoxin, warfarin, cimetidine, phenobarbital da wasu mutane. Magungunan da ke dauke da sinadarai na daskarewa da kuma karuwar potassium (Triamteren, Amiloride, da sauransu) na iya haifar da karuwa a wannan kashi a cikin jini. Haɗuwa tare da magungunan anti-inflammatory marasa steroidal na iya rage tasirin maganin da aka bayyana.
Thiazive diuretics tare da losartan zai haifar da raguwa cikin matsin lamba a cikin jijiya.
Kudin shiga tare da sauran magungunan rigakafi na iya rage hawan jini.
Magunguna waɗanda ke da tasiri kan RAAS (Captopril, Lisinopril, da dai sauransu) na iya lalata aikin renal da haɓaka abubuwan urea da creatinine bisa ga ma'aunin dakin gwaje-gwaje.
Amfani da barasa
Don hana tasirin da ba'a so a kan tsarin zuciya da jijiyoyin jini ba za a haɗe shi da abubuwan da ke sa maye ba. Yin amfani da lokaci ɗaya zai iya haifar da raguwa mai yawa a cikin karfin jini, cin zarafin ayyukan ciki, hanta, da kodan.
Analogs
- Angizar (Indiya).
- Gizaar (Amurka).
- Cardomin-Sanovel (Turkey).
- Losartan (Isra'ila).
- Lozarel (Switzerland).
- Lorista ND (Slovenia).
- Lozap da (Czech Republic).
- Erinorm (Serbia).
Yanayin hutu Lorista 12.5 daga kantin magani
Zan iya siye ba tare da takardar sayan magani ba
Ba a ba da magani ba tare da takardar sayan likita ba.
Farashin Lorista 12.5
Farashin ya bambanta dangane da masana'anta, yawan Allunan a cikin kunshin da kuma wurin siyarwa. Matsakaicin farashin - daga 180 zuwa 160 rubles kowace kunshin.
Yanayin ajiya na miyagun ƙwayoyi
A cikin bushe, wuri mai duhu a zazzabi wanda bai wuce 30ºС ba. Ka nisanta daga yara da dabbobi.
Ranar karewa
Adana sama da shekaru 2 daga ranar da aka ƙera.
Mai gabatarwa Lorista 12.5
Kamfanin sarrafa magunguna JSC Krka, ne, Novo mesto ya samar da shi a Slovenia. A Rasha, ana aiwatar da samarwa ta hanyar KRKA-RUS LLC a cikin garin Istra, Yankin Moscow.
Nazarin Lorista 12.5
Likitocin zuciya
Arina Ivanovna, likitan zuciya, Omsk
Lokacin ɗaukar wannan magani, yana da mahimmanci la'akari da duk contraindications da nuances na shan shi. Musamman ma a hankali don yin alƙawura ga mutanen da ke fama da matsalar kumburi, tare da rashin haƙuri ga babban ɓangaren, tare da cututtukan zuciya da na jijiyoyin ciki, ciki da shayarwa. Yana da mahimmanci a gargaɗi cewa kafin ƙarshen hanyar ya zama dole a guji shan giya don duk tsawon lokacin jiyya tare da kwanciyar hankali na kwanaki 5-7 bayan ƙarshen shan Allunan don cire kayan daga jikin.
Pavel Anatolyevich, likitan zuciya, Samara
Ana amfani dashi da yawa a hade tare da wasu kwayoyi, kuma kamar yadda monopreching ba ya nuna babban tasiri. Kyakkyawan inganci Na yi la'akari da ikon kare kodan a cikin marasa lafiya da ke fama da nau'in sukari na 2 na sukari da proteinuria. Farashin yana da matsakaici, wanda ke sa maganin ya zama araha ga kusan dukkanin rukunin marasa lafiya.
Rashin kyau shine babban tayi, wanda yasa ba zai yiwu ayi amfani dashi ba yayin daukar ciki.
Alexey Stepanovich, likitan zuciya, Norilsk
Dangane da sake duba marasa lafiya, an yarda da shi sosai, matsin lamba yana raguwa a hankali kuma a hankali, ya dace da matasa da tsofaffi.
Na lura da sakamako masu illa sau ɗaya kawai - wani mutum yana da shekara 49 ya fara jin zafi, a sakamakon wanda ya kasa hawa mota. A wannan yanayin, an maye gurbin maganin.
Marasa lafiya
Andrey, 30 years old, Kursk
Ya sha kwayoyin magani kamar yadda likitan kwalliyar ya tsara. Maganin farko shine 50 MG, sannan a hankali ya kara zuwa 150 MG. Yana aiki da kyau, babu wasu sakamako masu illa. Kuma farashin bai yi yawa ba.
Olga, mai shekara 25, Aktyubinsk
An sanya shi ga inna don kare kodan, saboda tana da ciwon sukari da furotin. Dangane da abubuwan lura, inna ta ji daɗi: matsin lambar ya tsaya. Kuma kuna yin hukunci ta hanyar binciken, adadin furotin a cikin fitsari ya ragu. Magungunan sun tafi daidai kuma babu alamun sakamako game da shan shi.
