A cikin nau'in allunan, babu Novostat, wannan ba irin nau'in magani ba ne. Ana samar da shi kawai a cikin nau'in capsules. Magungunan yana da tasirin sakamako na hypoliplera, ana amfani dashi a magani don daidaita matakan cholesterol kuma azaman wakili na anti-sclerotic.
Akwai abubuwan da aka saki da kuma abubuwan da aka tsara
Ana samun magungunan a cikin capsules, abu mai aiki a cikinsu shine atorvastatin alli trihydrate.
Jikin capsules farar fata ne, mai kauri, murfi yana da launin m-launin launi. Babban abin ƙunshi yana cikin adadin 10, 20, 40 ko 80 MG. Additionalarin ƙarin abun da ke ciki ana wakiltar shi da lactose monohydrate, sodium lauryl sulfate, cellulose, carbon dadinin kalma, povidone da magnesium stearate. Maganin kwalin kanta an yi shi ne da gelatin tare da ƙari da dioxide titanium da kuma rushewar E172.
Fayilolin salula suna dauke da capsules 10 kuma ana rarraba su a cikin kwalaye a cikin adadin blister 3.
Fayilolin salula suna dauke da capsules 10 kuma ana rarraba su a cikin kwalaye a cikin adadin blister 3. Ana iya sayar da capsules a cikin kwalba na filastik na 10, 20, 30, 40, 50, 60 ko 100 inji mai kwakwalwa. A cikin wani kwali mai kunshe sanya irin wannan 1.
Sunan kasa da kasa mai zaman kansa
INN na maganin shine Atorvastatin.
ATX
Magungunan suna da lambar ATX na C10AA05.
Aikin magunguna
An bayar da sakamakon warkarwa na Novostat saboda sashin aiki mai aiki - atorvastatin. Wannan fili ya kasance na mutum-mutumi kuma yana nuna kaddarorin hypocholesterolemic. Yana hana ayyukan HMG-CoA reductase, yin aiki azaman mai inhibitor m tare da zaɓin aiki. Ingantaccen enzyme shine farkon hanyar mevalonate na biosynthesis na steroids, ɗayan abubuwan da ke haifar da shine cholesterol.
An bayar da sakamakon warkarwa na Novostat saboda sashin aiki mai aiki - atorvastatin.
Atorvastatin kuma yana ƙaruwa da takamaiman maganin hepatoreceptors, wanda ke haifar da karɓar ƙwayar lipoproteins mai yawa (LDL). Godiya ga aikin miyagun ƙwayoyi, maida hankali ya faɗi:
- jimlar cholesterol - by 40% (a kan matsakaici);
- apoB - ta hanyar 51%;
- LDL - ta hanyar 42%;
- triglycerides - da kashi 24%.
A lokaci guda, an lura da haɓakar ƙwayoyin cholesterol-lipoproteins (HDL) da apoA.
Hakanan wannan magani yana da tasiri ga marasa lafiya waɗanda suke da nau'in homozygous na familial hypercholesterolemia, wanda ke da ƙima ga aikin wasu magunguna masu rage kiba. Sakamakon shan, yiwuwar haɓaka bugun jini, sauran cututtukan zuciya, ischemia tare da angina pectoris da ciwon zuciya, mutuwar zuciya da jijiyoyin jini yana raguwa. Ba a sami sakamako mai illa da illa ba.
Pharmacokinetics
Atorvastatin yana saurin narkewa a cikin narkewa, yana zuwa matsakaicin ƙwayar plasma 1-2 sa'o'i bayan gudanarwa, amma bioavailability ɗin sa bai wuce 14% ba saboda cutar malabsorption da kuma “sabon-wucewa”. Kimanin kashi 98% yana daure wa garkuwar jini, saboda haka hemodialysis bashi da amfani. A gaban abinci, rarar shigar da magunguna a cikin jini yayi saurin sauka.
Tare da lalacewar hanta, taro na atorvastatin yana ƙaruwa sosai.
Magunguna na kwayoyi suna faruwa ne musamman a hanta. Dangane da aikin kimiyyar magunguna, wasu daga cikin metabolites dinsu ba su da ƙarancin kayan farawa - suna lissafin kusan kashi 70% na abubuwan hana ƙonewa akan HMG-CoA reductase. Tare da fitsari, ba fiye da 2% na kashi da aka dauka ana keɓe shi ba.
Tare da lalacewar hanta, taro na atorvastatin yana ƙaruwa sosai. Rabin rayuwar miyagun ƙwayoyi shine sa'o'i 14, amma tasirin warkewa ya wuce har zuwa sa'o'i 30 bayan shan 1 na Novostat.
Alamu don amfani
A haɗe tare da maganin rage cin abinci da aikin motsa jiki, an wajabta magungunan don samun sakamakon hypoliplera na statins - rage ƙwaƙwalwar ƙwayar cuta, LDL, sarrafa ƙara yawan haɗakar apolipoprotein B da mahadi triglyceride. Alamu don amfani:
- hypercholesterolemia (na farko, dangi ko mara gado);
- hyperglyceridemia;
- hadewar hyperlipidemia:
- take hakkin metabolism na lipoprotein;
- nau'in dysproteinemia II (a da b);
- Fredrickson nau'in ƙwayar lipid na IV, yana nuna juriya ga tsarin abincin abinci;
- dysbetalipoproteinemia da cututtukan da suka danganci juna.
An sake yin amfani da wani kayan aiki don rigakafin cututtukan zuciya, ba tare da la'akari da alamomin cholesterol ba:
- masu ciwon sukari;
- masu shan sigari;
- masu cutar hawan jini;
- marasa lafiya tare da ƙarancin HDL;
- mutane tare da yanayin gado ga cututtukan tsarin zuciya.
Hakanan ana amfani da magani ga marasa lafiya da hypercholesterolemia tare da rigakafin sakandare na bugun jini, bugun zuciya, tashin zuciya, ciwon zuciya da kuma rage yiwuwar mutuwa. Hakanan, an wajabta magunguna idan ya cancanta, don aiwatar da matakan dawo da bangon jijiyoyin jiki (farfadowa).
Contraindications
Bai kamata a sha magungunan tare da yawan tashin hankali zuwa atorvastatin, rashin yarda da lactose ko wasu abubuwan maganin ba. Sauran abubuwan contraindications:
- cutar hanta
- haɓaka ayyukan hanta enzymes;
- na kullum mai shan giya;
- matsanancin ciwo na ciki;
- cuta cuta na rayuwa;
- tsananin rauni na jiki;
- ciki da shayarwa;
- shekaru har zuwa shekaru 10.
Novostat an haramta shi da rauni mai rauni a jiki.
Tare da kulawa
Ya kamata a yi taka tsantsan da hankali a gaban rashin daidaituwa na electrolyte, rikicewar endocrine, tarihin rashin lafiyar hepatic. Ba'a ba da shawarar sanya Novostat ga yara da matasa.
Yadda ake ɗauka
Da farko kuna buƙatar yin ƙoƙarin daidaita ƙwayar cholesterol a cikin wasu hanyoyi, kazalika da kulawa da kulawa game da babban maganin cututtukan ƙwayar cuta da kuma rasa nauyi (tare da kiba ko halin da ake ciki).
Capsules sun bugu ko da kuwa lokacin rana ko abinci. Ba a cimma sakamako mai warkewa nan da nan ba - aƙalla makwanni 2 ya kamata tun kafin fara shan Novostat. Kuma bayan makonni 4 sakamakon zai iya zama mafi ƙaranci kuma zai iya kasancewa har zuwa ƙarshen karatun warkewa. Likita ya ba da umarnin sashi kuma ya lura da yanayin haƙuri. Aikin yau da kullun ya dogara da matakin cholesterol, manufofin warkewa da kuma amsawar mutum na magani.
Ana kula da yawan ƙwayar maganin ƙwayar cuta ta plasma a kai a kai kuma ana daidaita magunguna. Don dalilai na hanawa, ana amfani da maganin a mafi ƙarancin kashi.
Tare da ciwon sukari
Statins yana haifar da ƙara ƙarancin haɗuwa a cikin glucose, wanda sauƙin kai tsaye ta hanyar abinci, motsa jiki da magungunan maganin cututtukan da aka saba. Ba a buƙatar gyaran gyaɗa.
Capsules sun bugu ko da kuwa lokacin rana ko abinci.
Side effects
Yawancin m halayen na iya faruwa.
Daga gabobin gabbai
Rashin tsawan sauraro.
Daga tsoka da kashin haɗin kai
Myopathy, myositis, arthralgia, cramps muscle.
Gastrointestinal fili
Dyspepsia, rashin abinci mai narkewa, gudawa, ciwon huhu.
Hematopoietic gabobin
Rage platelet maida hankali ne.
Tsarin juyayi na tsakiya
Migraines, rashin bacci, neuropathy, paresthesia, rauni tsoka, rauni.
Daga urethra, akwai rauni daga tashin hankali.
Daga tsarin numfashi
Bronchospasm.
Daga tsarin kare jini
Ya raunana kaciya, gazawar koda.
Daga tsarin zuciya
Maganin jini na jini.
Daga gefen metabolism
Canja cikin sukari na jini.
A lokuta da dama, allunan na iya haifar da asarar kai.
Cutar Al'aura
Cutar mahaifa, aski, rashin lafiya.
Tasiri kan ikon sarrafa abubuwan inji
Ya kamata ka guji ayyukan da ke buƙatar taro.
Umarni na musamman
Kada kayi amfani don asarar nauyi - miyagun ƙwayoyi ba su da irin waɗannan kaddarorin.
Yi amfani da tsufa
Babu buƙatar canza sashi.
Canje-canje na sashi a cikin tsofaffi ba lallai ba ne.
Aiki yara
Ba za ku iya tsara magunguna ga yara 'yan ƙasa da shekara 10 ba. Ana amfani dashi don hyperlipidemia idan yaro yana cikin haɗari ko yana da tsinkayar ciki don cutar cututtukan zuciya tare da yawan mace-mace. Ana amfani da maganin tare da ƙarancin maganin maganin rage cin abinci. A baya can, ya kamata ka fara tunanin aikin motsa jiki kana kula da cutar da take yi. Hadarin kamuwa da cutar sankarar mahaifa yana da yawa.
Yi amfani da lokacin daukar ciki da lactation
Ba za a iya shan miyagun ƙwayoyi ta hanyar mata masu juna biyu da mata masu haihuwa ba, da yiwuwar samun juna biyu ya yi yawa saboda sakaci da masu hana haihuwa. Iyaye mata masu shayarwa kuma ba sa yin magani har sai an daina shayar da jarirai nono.
Amfani don aikin hanta mai rauni
Kwayar cuta mai zurfi ta tsarin hanta da kuma ƙara yawan aiki na transaminases sune tsauraran matakan ɗaukar Novostat.
Yawan damuwa
Zai yiwu rushewar hanta da rhabdomyolysis. An bada shawara don kurkura ciki kuma ɗauka da sorbent. Jiyya kawai ake yi.
Tare da yawan abin sama da ya kamata, cin zarafin hanta mai yiwuwa ne.
Yin hulɗa tare da wasu kwayoyi
Amfani da Novostat a lokaci guda tare da Erythromycin, Cyclosporin, Niacin, azoles da shirye-shiryen fibroic acid yana kara haɗarin cutar ta zuciya. Babban allurai na ƙwayoyi na iya haifar da tsalle-tsalle a cikin taro na digoxin. Erythromycin, clarithromycin da ruwan 'ya'yan itacen innabi suna haɓaka matakan atorvastatin. Canjin canji a cikin sigogin magunguna na ethinyl estradiol da rigunan mata na northisterone. A gaban colestipol, abubuwan inganta lipid na magungunan biyu suna inganta juna.
Amfani da barasa
An bada shawara a guji shan giya.
Analogs
Abubuwan da ke aiki da Novostat wani ɓangare ne na irin waɗannan kwayoyi:
- Atorvastatin;
- Atoris;
- Torvacard
- Tulip;
- Livostor;
- Atorvacor da sauransu
Abubuwan da ke aiki da Novostat wani ɓangare ne na Tulip.
Yanayin hutu don Novostat daga kantin magani
Babu magani a cikin jama'a.
Zan iya siye ba tare da takardar sayan magani ba
An fito dashi ne kawai akan gabatar da girke-girke.
Farashi
Capsules 10 MG kudin daga 60 rubles. na inji 10.
Yanayin ajiya na Novostat
Ya kamata a adana miyagun ƙwayoyi a yanayin zafi har zuwa + 25 ° C daga hasken rana.
Ranar karewa
Shekaru 3
Mai masana'anta
A cikin Rasha, Novostat an ƙera ta ta ALSI Pharma CJSC da Biocom CJSC.
Ra'ayoyi game da Novostat
Polina, shekara 24, Lipetsk
An yi amfani da maganin ne don kakan saboda ƙwayar cuta mai yawa. Ya sha magani har tsawon lokaci, yanayinsa ya inganta. Abin sani kawai ya zama dole a sanya idanu a kai a kai don kada kakan ya keta abincin. Mun gamsu da sakamakon maganin, babu korafi game da sakamako masu illa.
Olga, mai shekara 54, Vyazemsky
Sakamakon yawan ƙwayoyin cuta, Dole ne in ɗauki waɗannan kalolin capsules, kuma har yanzu a kai a kai zuwa asibiti, sau da yawa ana yin gwaje-gwaje kuma ci gaba da cin abinci. Babu wani mummunan sakamako. Ko watakila sun kasance masu rauni, kuma ban kula ba. Kyautatawa ya fara inganta wani wuri a sati. Tun da na sha duka hanya, a karo na farko cikin dogon lokaci zan iya cewa ina jin dadi.
