Dalilin da ya sa ya kamu da cutar zuciya shi ne hauhawar jini, wanda aka bayyana a cikin hawan jini. Wannan yana rage ingancin rayuwar mutum. Masana sun ba da shawarar yin amfani da magungunan antihypertensive daban-daban waɗanda ke toshe homonin oligopeptide (angiotensins) waɗanda ke haifar da vasoconstriction. Wadannan kwayoyi sun hada da Lorista ko Losartan.
Ta yaya waɗannan kwayoyi suke aiki?
Hawan jini zai iya haifar da canje-canje a cikin bangon jijiyoyin jini a cikin dukkan gabobin. Wannan shine mafi haɗari ga zuciya, kwakwalwa, retina da kodan. Abubuwan da ke aiki na waɗannan magungunan guda biyu (potassium losartan) suna toshe angiotensins, suna haifar da vasoconstriction da haɓaka matsin lamba, wanda ke haifar da sakin sauran kwayoyin halittar (aldosterones) daga tasirin adrenal zuwa cikin jini.
Lorista ko Losartan sune magungunan antihypertensive wanda ke toshe jijiyoyin jini (angiotensins) wadanda ke haifar da vasoconstriction.
A karkashin tasirin aldosterone:
- reabsorption (sha) na sodium yana haɓaka tare da riƙe shi a cikin jiki (Na inganta hydration, yana da hannu a cikin fitowar samfuran samfuran koda, yana ba da ajiyar alkaline na jini plasma);
- yawan N-ion da ammonium an cire su;
- a cikin jiki, ana jigilar chlorides a cikin sel kuma suna taimakawa don guje wa bushewa;
- yawan hawan jini yana ƙaruwa;
- ma'aunin acid-base an daidaita shi.
Lorista
Ana yin magani mai guba a cikin nau'ikan allunan da aka sanya masu ciki, sun hada da potassium losartan, kazalika da ƙarin kayan abinci:
- cellactose;
- silicon dioxide (sorbent);
- magnesium stearate (ƙwanƙwasa);
- micronized gelatinized masara sitaci;
- hydrochlorothiazide (diuretic da aka haɗu don kare aikin koda wanda aka samo a cikin analogues na Lorista, kamar Lorista N da ND).
A wani ɓangare na m kwasfa:
- abu mai kariya mai amfani da jini (tsari mai laushi);
- plasticizer propylene glycol;
- dyes - quinoline (E104 rawaya) da dioxide dioxide (farar E171);
- foda talcum.
Abin da girke-girke na cake za a iya amfani dashi don masu ciwon sukari?
Cardioactive Taurine: alamomi da contraindications ga miyagun ƙwayoyi.
Karanta game da manyan abubuwan da ke haifar da ciwon sukari a wannan labarin.
Abunda yake aiki, yana hana angiotensin, yana sa ƙin jijiyoyin mara wuya. Wannan yana taimakawa wajen daidaita matsin lamba. Losartan an sanya shi:
- tare da alamun farko na hauhawar jini a cikin monotherapy;
- tare da hauhawar hauhawar jini a cikin hadadden tsarin kulawa;
- ciwon sukari cores.
Ana samar da Lorista a 12.5, 25, 50 da 100 MG na babban abu a cikin kwamfutar hannu 1. Sanya cikin 30, 60 da 90 inji mai kwakwalwa. a cikin kwali. A cikin matakan farko na hauhawar jini, an wajabta 12.5 ko 25 MG kowace rana. Tare da haɓaka a cikin matakin hauhawar jini, ƙara yawan amfani yana ƙaruwa. Dole ne a amince da tsawon lokacin hanya da sashi tare da likitan halartar.
Abubuwa masu aiki Lorista yana hana angiotensin aiki yana sa ƙin jijiyoyin mara wuya. Wannan yana taimakawa wajen daidaita matsin lamba.
Losartan
Ana ɗaukar nau'ikan a baka kuma yana dauke da 25, 50 ko 100 MG na babban bangaren da ƙarin abubuwa a cikin kwamfutar hannu 1:
- lactose (polysaccharide);
- cellulose (fiber);
- silikion dioxide (emulsifier da ƙari abinci E551);
- magnesium stearate (emulsifier E572);
- ssumum (croscarmellose sodium);
- povidone (enterosorbent);
- hydrochlorothiazide (a cikin shirye-shiryen Lozartan N Richter da Lozortan Teva).
Shafi fim ya hada da:
- emollient hypromellose;
- dyes (fari titanium dioxide, yellow iron oxide);
- macrogol 4000 (yana ƙara yawan ruwa a jiki);
- foda talcum.
Losartan, yana hana angiotensin, yana taimakawa wajen dawo da aiki na yau da kullun ga kwayoyin halitta:
- ba ya shafar ayyukan ciyayi;
- baya haifar da vasoconstriction (vasoconstriction);
- rage juriyarsu na waje;
- yana daidaita matsin lamba a cikin aorta da a cikin da'irori na karancin jini;
- yana rage hauhawar jini na jini;
- yana sauƙaƙa sautin a cikin tasoshin huhun ciki;
- yana aiki kamar diuretic;
- ya bambanta da tsawon lokacin aiki (fiye da kwana ɗaya).
Magungunan yana sauƙaƙe daga narkewa, narkeolized a cikin ƙwayoyin hanta, mafi girman jini a cikin jini yana faruwa bayan awa daya, yana ɗaukar nauyin protein na 95% na metabolite mai aiki. Losartan yana fitowa ba tare da canzawa tare da fitsari (35%) da bile (60%). Sashin halayen ya haɗu har zuwa 200 MG kowace rana (an kasu kashi biyu).
Losartan, yana hana angiotensin, yana taimakawa wajen dawo da aiki na yau da kullun na gaba ɗaya.
Kwatanta Lorista da Losartan
Aikin magungunan biyu yana da niyya don rage matsin lamba. Yawancin marasa lafiya da ke fama da tashin hankali suna ba da umarni a kansu, tunda an gano sakamako mai amfani duka a cikin rigakafin cututtukan zuciya da na jijiyoyin bugun gini, kuma a matsayin babban maganin cututtukan yanayi. Magunguna ba safai suna haifar da sakamako masu illa ba, suna da alamomi iri daya iri da kuma bambance-bambance.
Kama
An tabbatar da ingancin magungunan ga marasa lafiya da ke fama da cutar hawan jini, tare da abubuwan haɗari kamar:
- tsufa;
- bradycardia;
- canje-canje na jijiyoyin jini a cikin hagu na ventricular myocardium wanda ya haifar da tachycardia;
- bugun zuciya;
- lokaci bayan bugun zuciya.
Magunguna da suka danganci sinadarin losartan sun dace a wannan:
- amfani da 1 sau ɗaya kowace rana (ko fiye da sau da yawa, amma kamar yadda wani kwararre ya umarta);
- liyafar ba ta dogara da abinci ba;
- abu mai aiki yana da sakamako mai tarawa;
- mafi kyawun hanya daga sati zuwa wata daya.
Magungunan suna da iri ɗaya:
- rashin lafiyan abubuwa;
- hypotension;
- ciki (na iya haifar da mutuwar tayi);
- lokacin lactation;
- shekaru har zuwa shekaru 18 (saboda gaskiyar cewa tasirin yara ba shi da cikakkiyar fahimta);
- hepatic dysfunction.
Ga marasa lafiya da matsalar koda, ba a contraindicated da magani da kuma za a iya wajabta idan akwai hydrochlorothiazide a cikin abun da ke ciki, wanda:
- na hanzarta kwararar jini na koda;
- yana haifar da tasirin nephroprotective;
- inganta tashin hankali urea;
- Yana taimaka rage jinkirin farkon gout.
Menene bambanci?
Bambancin da ke akwai tsakanin waɗannan kayan aikin an ƙaddara shi galibi farashi da mai ƙira. Lorista samfuri ne na kamfanin Slovenian KRKA (Lorista N da Lorista ND sune Slovenia suka haɗu tare da Rasha). Godiya ga bincike na ƙwararru, babban kamfanin samar da magunguna tare da suna a kasuwannin duniya yana tabbatar da ingancin maganin.
Losartan an samar da shi a cikin Ukraine ta Vertex (Losartan Richter - Hungary, Losartan Teva - Isra'ila). Wannan analog ne mai rahusa na Lorista, wanda baya nufin halaye masu rauni ko ƙarancin inganci. Istswararrun likitoci waɗanda ke ba da wannan magani ko wannan maganin, sun lura da wasu bambance-bambance, sun haɗa da sakamako masu illa.
Lokacin amfani da Lorista:
- a cikin 1% na lokuta, ana haifar da arrhythmia;
- Ana lura da alamun, yana haifar da tsoratar da hydrochlorothiazide (asarar potassium da sodium salts, anuria, gout, proteinuria).
An yi imani da cewa losartan ya fi sauƙi a ɗauka, amma da wuya ya haifar da:
- a cikin 2% na marasa lafiya - don haɓakar zawo (ƙwayar macrogol shine tsokaci);
- 1% - don myopathy (jin zafi a baya da tsokoki tare da haɓakar murfin tsoka).
A cikin lokuta masu wuya, losartan na iya shafar ci gaban zawo.
Wanne ne mafi arha?
Kudin ya rinjayi dalilai kamar su ƙasar ƙasar, gabatarwa da rangwamen kuɗi, adadi da girma na irin fitowar da aka gabatar.
Farashin Lorista:
- 30 inji mai kwakwalwa 12.5 MG kowane - 113-152 rubles. (Lorista N - 220 rubles.);
- 30 inji mai kwakwalwa 25 MG kowane - 158-211 rubles. (Lorista N - 302 rubles, Lorista ND - 372 rubles);
- 60 inji mai kwakwalwa. 25 MG kowane - 160-245 rubles. (Lorista ND - 570 rubles);
- 30 inji mai kwakwalwa 50 MG kowane - 161-280 rubles. (Lorista N - 330 rubles);
- 60 inji mai kwakwalwa. 50 MG kowane - 284-353 rubles;
- 90 inji mai kwakwalwa 50 MG kowane - 386-491 rubles;
- 30 inji mai kwakwalwa 100 MG kowane - 270-330 rubles;
- Shafin 60. 100 MG - 450-540 rubles;
- 90 inji mai kwakwalwa 100 MG kowane - 593-667 rubles.
Kudin losartan:
- 30 inji mai kwakwalwa 25 MG kowane - 74-80 rubles. (Losartan N Richter) - 310 rubles .;
- 30 inji mai kwakwalwa 50 MG kowane - 87-102 rubles;
- 60 inji mai kwakwalwa. 50 MG kowane - 110-157 rubles;
- 30 inji mai kwakwalwa 100 MG - 120 -138 rubles;
- 90 inji mai kwakwalwa 100 MG kowane - har zuwa 400 rubles.
Daga jerin da ke sama ya bayyana sarai cewa yana da fa'idodi sosai don siyan losartan ko kowane magani, amma tare da adadi mai yawa a cikin kunshin guda ɗaya.
Menene mafi kyawun lorista ko losartan?
Wanne magani ne mafi kyawu, ba shi yiwuwa a faɗi ba tare da matsala ba, tunda sun dogara ne akan abu ɗaya mai aiki. Wannan likitan halartar ya kamata ya zuga wannan, gwargwadon halayen mutum na mai haƙuri. Amma lokacin amfani dashi, sakamakon ƙarin abubuwan haɗin da aka haɗa cikin shirye-shiryen dole ne a la'akari.
Sakamakon gaskiyar cewa Lorista yana faruwa da ƙarancin magani (12.5 mg), an wajabta shi don hana yanayin hauhawar jini, kasancewar bugun zuciya na yau da kullun, a cikin yanayin canje-canje na spasmodic a matakin matsin lamba. Lallai, tare da yawan zubar karfin jini wanda yake rikitarwa zai yiwu, wanda kuma yake kawo hadari ga mara lafiyar, tunda alamomin sa ba su bayyana kai tsaye. Bayyanar hauhawar jini tare da hauhawar tashin hankali da raguwar hauhawar jini za a iya sarrafa shi ta hanyar karamin magani wanda aka sha sau biyu.
Neman Masu haƙuri
Olga, 56 years old, Podolsk
Ba zan iya ɗaukar waɗannan magungunan da mai warkarwa suka umurce ni ba. Na farko na sha maganin yau da kullun na 50 mg na losartan. Wata daya bayan haka, kwayar jini ta bayyana a hannayen (suka karu kuma suka fashe a hannayen). Askorutin ya daina shansa kuma ya fara sha, kamar dai yanayin da tasoshin ke gudana. Amma matsin lambar ya ragu. An koma Lorista mafi tsada. Bayan ɗan lokaci, komai ya maimaita. Na karanta a cikin umarnin - akwai irin wannan sakamako. Yi hankali!
Margarita, shekara 65, garin Tambov
An tsara shi zuwa Lorista, amma ya canza zuwa Losartan. Me yasa ƙarin biyan kuɗi don magani tare da abu guda mai aiki?
Nina, ɗan shekara 40, Murmansk
Hauhawar jini cuta ce ta ƙarni. Matsayi a wurin aiki da a gida a kowane zamani yana ɗaga matsin lamba. Sun shawarci Lorista azaman amintacciyar hanyar, amma a cikin bayani ga maganin akwai magunguna masu yawa. Bayan na karanta umarnin, sai na yanke shawarar sake neman likita.
Cutar ciki ne contraindication zuwa shan duka kwayoyi.
Binciken masana game da lafiyar zuciya akan Lorista da Losartan
M.S. Kolganov, likitan zuciya, Moscow
Wadannan kudade suna da raunin da ya dace na ɗaukacin rukunin masu hana ƙwaƙwalwar angiotensin. Sun ƙunshi gaskiyar cewa tasirin yana faruwa a hankali, saboda haka babu wata hanyar da za a iya warkar da hawan jini na hanzari.
S.K. Sapunov, likitan zuciya, Kimry
A cikin abubuwanda ke tattare da dukkanin hanyoyin hanawa na angiotensin na nau'in na biyu, Losartan ne kawai ya sadu da alamomin hukuma 4 don amfani: hauhawar jini; hauhawar jini sakamakon hawan jini na ventricular hagu; nau'in 2 cututtukan ƙwaƙwalwar ƙwayar cuta guda biyu; na kullum zuciya.
T.V. Mironova, likitan zuciya, Irkutsk
Wadannan kwayoyin hana daukar ciki suna kiyaye yanayin sosai idan suka ci gaba. Tare da maganin warkewar cutar, ana rage raguwar yiwuwar rikice rikice. Amma a cikin m jihar ba su taimaka. Aka saya da takardar sayan magani
