Magungunan Vozulim: umarnin don amfani

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Wannan insulin mutum ne wanda injiniyoyin kwayoyin halitta suka kirkira. Ana amfani dashi don kula da ciwon sukari na 1 ko 2.

Sunan kasa da kasa mai zaman kansa

Inulin na injiniyan ɗan adam.

Vozulim insulin mutum ne wanda injiniyoyin kwayoyin halitta suka kirkira, wadanda ake amfani dasu don magance nau'in 1 ko nau'in ciwon sukari na 2.

ATX

A10AB01.

Saki siffofin da abun da ke ciki

Akwai shi ta hanyar samar da mafita don allura (dakatarwa don gudanar da subcutaneous). 1 ml ya ƙunshi 100 IU na aiki insulin. A cikin kwalban - 10 ml na bayani. A cikin alkalami mai iya diski - 3 ml na mafita a cikin kayan.

Aikin magunguna

Ma'aunin hypoglycemic ne na matsakaici na tsawon lokaci. Ya yi daidai da insulin ɗan adam, duk da cewa injin ne ya ƙirƙira shi. Yana hulɗa tare da masu karɓar membrane na waje kuma yana samar da hadadden hadaddun tare dasu.

Yana haɓaka aikin AMP na cyclic a cikin mai da ƙwayoyin hanta. Zai iya shiga cikin ƙwayar tsoka. Yana haɓaka samuwar pyruvate kinase, hexokinase, glycogen synthetase a matakin ciki.

Sakamakon kunnawa na tafiyar hawainiya na glucose, mai nuna wannan kayan a cikin jini yana raguwa. Yana ƙarfafa samuwar mai, glycogen, furotin. Yana rage yawan samuwar glucose a cikin hanta hanta.

Yawancin metabolites na maganin suna dauke da kodan.

Pharmacokinetics

Abubuwan da aka fara amfani da wannan kayan sun dogara da hanyar (s / c ko IM) da wurin allurar, da kuma gwargwadon ƙwayar sinadarin. An rarraba shi ba daidai ba cikin kyallen takarda, ba ya yaduwar katangar mahaifa kuma zuwa cikin madarar nono.

Metabolism yana faruwa tare da taimakon enzyme insulinase a cikin kodan da hanta. Yawancin metabolites suna dauke da kodan.

Alamu don amfani

An nuna masa magani:

  • nau'in insulin-dependant type 1 ciwon sukari;
  • nau'in ciwon sukari guda 2;
  • m juriya daga jiki zuwa sukari-ragewan na baka kwayoyi, kazalika da m juriya da su, idan har cewa hadaddun far da za'ayi;
  • cutuka.

Contraindications

An sanya maganin a cikin hypoglycemia. Ba'a ba da shawarar don ƙwayar hankalin ƙwayar jiki ga insulin da sauran abubuwan da aka gyara daga maganin.

Yadda ake ɗaukar Vulim?

Bayan haka, kusan rabin awa kafin karin kumallo. Dole ne a canza wurin allurar a koyaushe. A cikin lokuta na musamman, an tsara aikin sarrafa intramuscular. An hana shi sosai don bayar da allura ta ciki na Vozulim.

Ana amfani da Vozulim a ƙarƙashin ƙasa, kusan rabin sa'a kafin karin kumallo.
Canja wurin mara lafiya zuwa wani insulin yana tare da sarrafa adadin glucose a cikin jini.
Mafi yawan tasirin sakamako na aikin insulin shine hypoglycemia.

An zabi sashi ne kawai daban-daban, la'akari da halaye na jiki da bukatun insulin. An gabatar da raka'a 8-24 kowace rana.

Idan kashi ya wuce 0.6 PIECES ta kilogram na nauyi, to kuna buƙatar saka allura 2 a cikin sassan jikin daban daban. Idan marasa lafiya sun karɓi fiye da 100 IU na insulin, to, lokacin da canza shi, kuna buƙatar zuwa asibiti. Canja wuri zuwa wani insulin yana tare da kulawa da hankali na yawan glucose a cikin jini.

Sakamakon sakamako na Vozulima

Mafi yawan tasirin sakamako na aikin insulin shine hypoglycemia. Ba kamar hyperglycemia ba, yana tasowa ba zato ba tsammani, kuma alamunta suna ƙaruwa da sauri. Marasa lafiya damu:

  • karuwar gumi;
  • palpitations
  • pallor na fata;
  • tsananin ciwon kai;
  • rikicewa;
  • zazzabi
  • yatsu masu rawar jiki;
  • jin numbasa a fuska;
  • tsananin jin yunwar;
  • tsalle a cikin karfin jini.

Idan ba a taimaki mai haƙuri ba, to rashin ƙarfi kawai zai haɓaka. Babban tsananin yanayin rashin jini yana haifar da haɓakar ƙima.

Anaphylactoid da sauran halayen rashin lafiyan suna da matukar wahala. Daga cikin halayen gida - zafi da kumburi a wurin allurar, kumburi. Yin amfani da dogon lokaci yana haifar da sabon abu na lipodystrophy.

Sakamakon sakamako na miyagun ƙwayoyi sun hada da tsalle-tsalle a cikin karfin jini.
Vozulim na iya haifar da yawan gumi.
Yayin maganin ƙwayar cuta, an lura da ƙarancin zuciya.
Bayan amfani da miyagun ƙwayoyi, ciwon kai sau da yawa yana bayyana, wanda alama ce ta sakamako na sakamako.
Babban tsananin yanayin rashin jini yana haifar da haɓakar ƙima.
A kan asalin shan miyagun ƙwayoyi, rikice-rikice na iya faruwa.
Shan maganin yana iya kasancewa tare da yatsunsu masu rawar jiki.

Sauran sakamako masu illa sun haɗa da ƙarami da canjin canji a cikin tunani. Wannan ya zama ruwan dare musamman a farkon farawar jiyya.

Tasiri kan ikon sarrafa abubuwan inji

Domin hypoglycemia mai yiwuwa ne, to mutane masu haɗarin ci gaban irin wannan yanayin ya kamata su guji tuƙin mota da kuma aiki tare da keɓaɓɓun hanyoyin.

Umarni na musamman

An zaɓi sashi koyaushe tare da taka tsantsan ga marasa lafiya waɗanda ke da raunin jijiyoyin wuya da cututtukan ƙwayar cuta.

Daidaita gyaran jiki ya zama dole don cututtukan cututtukan cututtukan zuciya, drenfunal adrenal glandon (cutar Addison), dys- ko hypopituitarism, gazawar koda, raunin koda. Tare da irin waɗannan cututtukan, wajibi ne don gudanar da gwaje-gwaje na likita na lokaci-lokaci.

Hypoglycemia yana faruwa tare da yawan yawan insulin, amai, gudawa, haɓaka aiki na jiki. Wani lokacin ma harda canza wurin allurar yakan haifar da raguwar adadin sukari na jini.

Rashin daidaituwa a cikin marasa lafiya da ke dauke da ciwon sukari na 1 shine ke haifar da ci gaba da hauhawar jini. An kwatanta shi da ƙishirwa, tashin zuciya, syncope, asarar abinci, da fatar fata. Daga marasa lafiya sukan zo warin acetone. Hyperglycemia na iya haifar da barazanar kamuwa da cutar ketoacidosis mai haɗari ga rayuwa.

Hyperglycemia na iya haifar da barazanar kamuwa da cutar ketoacidosis mai haɗari ga rayuwa.
Gyara ƙwayar Vozulima ya wajaba don gazawar koda koda.
Amai na iya haifar da raguwar yawan sukarin jini.
A cikin cututtukan glandar thyroid, ya zama dole don daidaita sashi na magani.
Activityara yawan aiki na jiki yana haifar da hauhawar jini.
Marasa lafiya shekaru 65 da haihuwa dole ne a hankali zaɓi sashi na miyagun ƙwayoyi.
Ba a hana yara sanya Wozulim ba.

Yi amfani da tsufa

Marasa lafiya waɗanda suka girmi shekaru 65 yakamata su zaɓi sigar magani a hankali kuma su kula da matsayin lafiyar lokacin magani.

Aiki yara

Ba a hana yara sanya wannan magani ba. Yayin maganin, ana kula da matsayin kiwon lafiya da glycemia koyaushe.

Yi amfani da lokacin daukar ciki da lactation

An yarda da amfani da wannan insulin idan mai haƙuri yana da ciki. Wajibi ne don yin la'akari da canje-canje a cikin bukatun insulin a cikin lokutan daban-daban na lokacin haila: raguwa a cikin farkon farkon da ƙara kaɗan a cikin sauran kwanakin. Bukatar hakan na raguwa kafin haihuwa kanta da kuma bayan haihuwar jariri.

Yayin shayarwa, mace ya kamata a lura da ita tsawon watanni, ya zama dole don a sami kwantar da hankali na bukatar insulin.

Aikace-aikacen aiki mara kyau

Tare da cututtukan koda, buƙatar jikin insulin na iya canzawa.

Amfani don aikin hanta mai rauni

Tare da cututtukan hanta, raguwa a cikin buƙatar jikin mutum don hormone yana yiwuwa. Idan kun ci gaba da sanya shi a cikin allurai iri ɗaya, to mara lafiyar na iya haɓaka ƙoshin kumburi, ya juya ya zama abin wutsi.

Yawan adadin Vozulim

Tare da yawan yawan zubar da jini, haɓakar jini na haɓaka. Saurin haɓaka wannan sabon abu shine halayyar mutum. Wani lokacin mai haƙuri na iya rasa hankali a cikin 'yan mintina kaɗan.

An yarda da amfani da Vozulima idan mai haƙuri yana da ciki.
Yakamata mai haƙuri ya ɗauki sukari idan ya ji alamun farko na raguwar sukari.
Tare da haɓakar ƙwayar cuta na hypoglycemic coma, ana gudanar da maganin dextrose a cikin jiyya ga mara haƙuri.

Ana sanar da duk mai fama da cutar sankara game da hadarin kamuwa da cutar sikari da kuma alamun farko na ci gabanta. Yana buƙatar ɗaukar sukari idan ya ji alamun farko na raguwar sukari.

Ana kula da matsanancin hypoglycemia a cikin asibiti. Idan an kiyaye ilimin mai haƙuri, to, ana sarrafa shi na dextrose (a baka, subcutaneously, intramuscularly ko intravenously). Ana yin allurar Glucagon. Tare da haɓakar ƙwayar cutar tarin ƙwaƙwalwar ƙwayar cuta, an samar da maganin rage ƙwaƙwalwa a cikin jet da cikin ciki. Tsawon lokacin gabatarwar sai mutum ya dawo hayyacin sa.

Yin hulɗa tare da wasu kwayoyi

Rikicin hypoglycemic lokacin da aka haɗu da wasu magunguna na iya ƙaruwa ko rage.

Intensarfafawar matakin ya haifar da:

  • magungunan sulfa;
  • MAO, ACE inhibitors;
  • abubuwanda ake amfani da su na salicylic acid;
  • steroids;
  • Bromocriptine;
  • maganin tetracycline;
  • Ketoconazole;
  • Clofibrate;
  • Fenfluramine;
  • Pyridoxine;
  • Quinidine;
  • Quinine da Chloroquinine;
  • duk shirye-shiryen da ke kunshe da ethanol.
Tare da haɗuwa da Ketoconazole da Vozulima, tasirin hypoglycemic na ƙarshen yana ƙaruwa.
Morphine yana rage tasirin cutar ta Vozulim.
Nicotine ya rage girman tasirin insulin.

Rage sakamakon:

  • Glucagon;
  • Harkar ciki;
  • duk hana daukar ciki;
  • madauki da thiazide diuretics;
  • Bromocriptine;
  • heparin;
  • shirye-shirye - alli masu maganin kazamin tubule;
  • morphine;
  • Diazoxide.

Masu fama da shan sigari suna buƙatar tuna cewa nicotine yana rage tasirin hypoglycemic na insulin. Thiazolidinediones yana ƙaruwa da ƙwaƙwalwar ƙwayoyin zuwa insulin.

Amfani da barasa

Marasa lafiya waɗanda ke karɓar insulin suna da rage haƙuri na ethanol. Barasa yana tsokanar ci gaban haila.

Analogs

  • Biosulin;
  • Gansulin;
  • Gensulin;
  • Insuman;
  • Insuran;
  • Protafan;
  • Rinsulin;
  • Humulin;
  • Pen Royal;
  • Bari mu yi mulki 30 70.
Me yasa kuma yaushe likitoci suka tsara insulin?

Magunguna kan bar sharuɗan

Ana fitar dashi ne kawai ta takardar sayan magani.

Zan iya saya ba tare da takardar sayan magani ba?

A'a.

Farashi

Kudin kwalban kwalba miliyan 10 kusan 600 rubles. Farashin abin da ya shafi alkalami shine kusan 990 rubles.

Yanayin ajiya na miyagun ƙwayoyi

Ya kamata a adana magungunan a wuri mai sanyi (zazzabi - daga +2 zuwa + 8ºC). An ajiye kwalban da aka buɗe ko alkairin sirinji a zazzabi a ɗakin. Dole ne a yi amfani dasu a cikin makonni 4.

Ranar karewa

Magungunan ya dace don amfani a cikin shekaru 2 daga ranar da aka ƙera shi. Haramun ne a sanya bayan wannan lokacin.

Mai masana'anta

An samar da shi a kamfanin Wokhard Towers, Bandra Kurla Complex, Bandra (Gabas), Mumbai.

Humulin yana da tasirin irin wannan a jiki.
Abun da yafi kama dashi shine Biosulin.
Rinsulin magani ne mai kama da wannan.
Kuna iya maye gurbin maganin tare da magani kamar Protafan.

Nasiha

Irina, 35 years old, Moscow: "Wannan shine insulin, wanda ke taimakawa ci gaba da kasancewa da glucose matakan al'ada. Insulins din da ya gabata ya haifar da rashin karfin jini, wani lokacin hangen nesa ya lalace .. Inje na Uzulim baya haifar da illa, yana kumburi a wurin allura .. Tare da wannan insulin da abincin da ya dace sarrafa don sarrafa ƙimar glucose kuma kada ku wuce 6 mmol. "

Pavel, mai shekaru 55, Nizhny Novgorod: "Wannan magani ya rage rage yawan glucose kuma baya bada izinin kwatsam. Magungunan da suka gabata ba su ba da irin wannan tasiri ba. Yanayina na lafiya sun inganta sosai, kuma babu tsalle-tsalle a cikin sukari tsawon watanni. Na lura cewa yanzu na ɗan ɗan ƙara inganta "Ina kuma bin tsarin cin abinci da abubuwan yau da kullun, don haka sukuna baya tsallakewa."

Natalia, ɗan shekara 49, St. Petersburg: "Ina da nau'in ciwon sukari na 1, Ina buƙatar allurar insulin koyaushe. Wasu kwayoyi sun haifar mini da ƙwaƙwalwar ƙwayar cuta, wanda wani lokacin yana da wuya a rushe. Tare da taimakon Vulizim, na sami damar ci gaba da sukari, lafiyar jikina yana inganta. yana yiwuwa a shawo kan cutar sankara kuma a hana ci gaba da rikice-rikice. "

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