Ana amfani da Siofor 500 don rage glucose jini. Hakanan ana amfani dashi a cikin lokuta inda ya zama dole don daidaitawa da rasa nauyi. Babban tasirin maganin yana faruwa ne sakamakon tasirin da ke tattare da shi: da yawa daga cikin hanyoyin nazarin halittu ana daidaita su yayin aikin jiyya.
Sunan kasa da kasa mai zaman kansa
Metformin
Ana amfani da Siofor 500 don rage glucose jini.
ATX
A10BA02
Saki siffofin da abun da ke ciki
A cikin kantin magunguna, zaka iya samun magunguna kawai a cikin nau'ikan allunan. A cikin ƙirar maganin da ake tambaya, sashin babban bangaren (metformin hydrochloride) an ɓoye shi - 500 MG. Akwai wasu nau'ikan magungunan da suka bambanta da adadin wannan sinadarin: 850 da 1000 mg.
Ana samar da miyagun ƙwayoyi a cikin fakitoci na sel waɗanda ke ɗauke da allunan 10 da 15. Jimlar adadin blister a cikin kwali na kwali: 2, 3, 4, 6, 8, 12.
Aikin magunguna
Siofor yana cikin rukunin wakilai na hypoglycemic. Magungunan yana cikin biguanides. Ana amfani dashi sau da yawa a cikin haɗin gwiwa tare da wasu hanyoyi. Haka kuma, ana bayar da maganin ne kawai ga masu fama da cutar rashin insulin. Kai tsaye miyagun ƙwayoyi ba su tasiri da asalin hormonal ba, kawai an lura da sakamako mai kai tsaye. Don haka, yayin jiyya tare da Siofor, ƙarfin samar da insulin ta hanyar ƙwayoyin ƙwayar ƙwayar cuta ba ya ƙaruwa. Koyaya, akwai karuwa a cikin hankalin mutum ga wannan hormone.
Hanyar aiwatar da metformin ta dogara ne akan maido da adadin hanyoyin nazarin halittu:
- ƙimar yin amfani da glucose yana ƙaruwa, a sakamakon haka, glycemia a hankali yana raguwa;
- da karfi na aiwatar da sha na carbohydrates ta gabobin narkewa kamar jini yana raguwa;
- samar da glucose a cikin hanta yana rage gudu;
- ofarfafawar inulin ɗin insulin kuma yana raguwa.
Saboda tasirin da ke tattare da tasirin ayyukan da ke ba da gudummawa ga yin aiki da amfani da glucose, an lura da raguwa a cikin ƙwayar jini. Baya ga wannan, sashin aiki mai aiki na Siofor yana shafar samar da glycogen. A lokaci guda, ƙarfin sufuri na kariya na glucose membrane yana ƙaruwa.
Siofor yana cikin rukunin wakilai na hypoglycemic.
Duk da kasancewar babu tasiri kai tsaye kan yadda ake samar da insulin, an lura cewa an rage raguwa a cikin yaduwar insulin da 'yanci. Tare da wannan, akwai karuwa a cikin rabo na insulin zuwa proinsulin. Godiya ga irin waɗannan matakan, ƙwaƙwalwar kyallen takarda zuwa wannan hormone yana ƙaruwa.
Koyaya, ƙwayar tana da tasiri akan metabolism na lipid. Ta wannan hanyar, samar da mai mai kyauta yana ci gaba kaɗan. Shan iskar shaka yana rage gudu. Sakamakon wannan, ƙaruwar aiwatar da mai metabolism yana raguwa, wanda ke taimakawa wajen daidaita nauyi. Hakanan yana rage yawan tasirin cholesterol (duka duka biyu da LDL), haka kuma triglycerides, kuma yana raguwa. Sakamakon haka, an lalata tsarin ɗerawar kitse. Godiya ga wannan, an rage nauyi akan asalin abincin da kuma kula da isasshen ƙarfin motsa jiki.
Wani fasalin na metformin shine ikon yin tasirin aikin thrombosis. Wannan dukiyar ta nuna rauni sosai. Godiya gareshi, Siofor yana haɓaka ɗaukar hoto na clots.
Pharmacokinetics
Abubuwan da ke aiki suna shiga cikin jinin jini daga narkewa, inda mucosa yake cikin hanzari. Allunan an rufe fim ɗin. Wannan dalilin yana taimakawa wajen sakin abu mai aiki a cikin hanji kawai. Mafi girman ƙwayar plasma na metformin ya kai bayan awa 2.5. Cin abinci yana ba da gudummawa ga rage shan kwayoyi.
Metformin yana ƙoƙarin yadawa cikin jiki. Koyaya, zuwa mafi girma, wannan sashin yana jinkirta ne kawai a wasu gabobin (hanta, kodan), da kuma a cikin ƙwayoyin hancin salivary. Rashin lafiyar kwayar halitta a cikin lafiyar jiki ya kai 60%. Siofor ya bambanta da analogues yayin da babu damar ɗaure wa sunadaran plasma.
Siofor 500 mai aiki da kayan aiki baya canji.
Abubuwan da suke aiki basa canji. Lokacin da aka cire shi daga jiki, kodan sun shiga. Rabin rayuwar shine awoyi 6.5. An lura cewa idan akwai aiki na keɓaɓɓen aiki, tare da raguwa a cikin haɗakar creatinine, ƙimar cire metformin daga jiki yana raguwa. Sakamakon haka, adadin abu mai aiki a cikin plasma nan da nan yana ƙaruwa.
Me aka wajabta masa?
Babban jagorar yin amfani da Siofor tare da maida hankali na metformin 500 MG shine lura da marasa lafiya da ke dauke da ciwon sukari na 2. Alamar amfani da wannan magani shine karuwar glucose na jini. Koyaya, za a iya sanya magani a cikin masu ciwon sukari da basu da insulin. Wannan shi ne saboda gaskiyar cewa Siofor yana ƙaruwa da ƙwaƙwalwar kyallen takarda zuwa insulin. Don haka, haɓaka wucin gadi a cikin abubuwan wannan hormone na iya haifar da rikice-rikice.
Maganin da ke cikin tambaya yana bada shawarar don amfani da kiba, wanda ya haɗu da asalin ciwon sukari. Koyaya, yana da kyau a yi amfani da Siofor tare da maganin rage cin abinci da motsa jiki mai tsayi. An wajabta wannan maganin tare da wasu magunguna. Sau da yawa ba sau da yawa (a cikin 5-10% na lokuta), ana bada shawara don amfani azaman matakan warkewa mai zaman kanta.
Alamar amfani da wannan magani shine karuwar glucose na jini.
Contraindications
Ba daidai ba ne a tsara maganin a irin waɗannan lokuta:
- nau'in ciwon sukari na 1;
- takamaiman yanayin mummunan yanayi ga mai aiki ko mai taimako a cikin tsarin Siofor;
- lalacewa da ƙwayar carbohydrate a cikin tushen ciwon sukari;
- yanayin cututtukan cututtukan fata wanda ya gabata;
- cututtuka da kuma wasu dalilai marasa kyau da ke ba da gudummawa ga aikin hanta mai rauni, waɗannan sun haɗa da mummunan cututtuka, rashin ruwa;
- cututtukan cututtukan da ke haifar da ci gaban hypoxia: aiki mai rauni na zuciya, tsarin numfashi, infarction myocardial, yanayin girgizawa;
- babban haɓaka mai mahimmanci a cikin abubuwan lactate, tare da cin zarafin pH na jini da kuma bayyanar rashin daidaituwa na electrolyte;
- guba na ethanol, shan barasa;
- maganin rage cin abinci, idan har adadin kuzari ya yi daidai ko kasa da 1000.
Tare da kulawa
Ana buƙatar kulawa ta musamman lokacin kula da yara daga 10 zuwa 12 shekara. Bugu da ƙari, dole ne a kula da hankali yayin ɗaukar miyagun ƙwayoyi a cikin tsufa (daga shekaru 60 ko sama da haka), muddin an nuna mara lafiya ga matsanancin ƙoƙarin jiki. A wannan yanayin, da yiwuwar haɓakar lactic acidosis, tare da rashin daidaituwa na electrolyte, karuwa a cikin abubuwan lactate da cin zarafin pH na jini, yana ƙaruwa.
Yadda ake ɗaukar Siofor 500?
An wajabta maganin a lokacin ko bayan abinci. An ƙayyade tsawon lokacin jiyya daban daban. Fara farawa na magani tare da ƙaramin abu. A hankali, adadin metformin yana ƙaruwa. Haka kuma, sashi ya kamata ya karu kowane mako. Godiya ga wannan, jiki yana dacewa da mafi kyawun kayan sunadarai.
An wajabta maganin a lokacin ko bayan abinci.
Ciwon sukari
A matakin farko, ya kamata a dauki 500-1000 MG na miyagun ƙwayoyi. A hankali, ana kaiwa yawan adadin maganin yau da kullun - 3000 MG (ga majinyata na manya). An ƙayyade kashi da kashi uku.
Ana aiwatar da kulawa da yara bisa ga umarnin guda ɗaya, amma tare da ɗan bambanci: a cikin makonni 2 na farko, 500 MG kowace rana ya kamata a sha. Sannan matsakaicin adadin Siofor na yau da kullun ya kai - 2000 mg (ga marasa lafiya daga shekaru 10 zuwa 18).
Don asarar nauyi
Ganin cewa likitan za a iya rubuta shi ne kawai ga mutanen da ke da cutar sankarar mellitus, don rage nauyin jiki, ya halatta a yi amfani da tsarin kulawa na yau da kullun. Haka kuma, dole ne a sanya tsarin rage cin abinci da matsakaitan motsa jiki. Magungunan da ake tambaya ba zai iya maye gurbin waɗannan matakan ba.
Side effects
Lactic acidosis yana haɓaka, shaye-shayen bitamin B12 ya rushe.
Gastrointestinal fili
Akwai asarar ɗanɗano, tashin zuciya yana bayyana, ƙasa da sau da yawa - vomiting. Zawo na iya faruwa. Wani lokacin akwai jin zafi a ciki. Abun ci yana da damuwa, kuma a lokaci guda akwai baƙin ƙarfe a bakin. Wadannan bayyanar cututtuka na iya ɓacewa da kansu idan aka ci gaba da maganin, shan miyagun ƙwayoyi sau 2-3 a rana. Hadarin cutar sakamako masu illa yana ƙaruwa a farkon matakin jiyya. A wannan yanayin, jikin bai riga ya daidaita da metformin ba.
Hematopoietic gabobin
Cutar amai da gudawa
A ɓangaren fata
Itching, hyperemia, kurji.
Cutar Al'aura
Urticaria.
Umarni na musamman
Metformin yana jin daɗin tarawa a cikin jiki yayin jiyya tare da Siofor. Tare da lalata hanta ko aikin koda, wannan tasiri yana da ƙarfi. Sakamakon karuwa a cikin taro na metformin, adadin lactic acid a cikin jini yana ƙaruwa. A sakamakon haka, lactic acidosis yana haɓaka. A wannan yanayin, ana buƙatar dakatar da aikin kai tsaye. Asibiti na mara lafiya ya zama dole.
Haɗin haɗarin metformin da abubuwan sha mai haɗari shine ke haifar da rikitarwa mai wahala.
Don hana haɓakar ci gaban lactic acidosis, duk dalilai masu haɗari an ƙaddara kuma, idan zai yiwu, an cire su yayin magani. Sanadin bayyanar cututtuka na wannan cutar:
- barasa
- gazawar hanta;
- azumi;
- hypoxia.
Kafin ɗaukar Siofor, ya zama dole don tantance matakin ƙirar halitta. Wannan shi ne saboda gaskiyar cewa kodan yana aiki da ƙodan.
Wajibi ne a sami hutu wajen shan maganin a cikin tambaya kafin gudanar da bincike ta amfani da wakilan abubuwan aidin. An katse hanyar aikin lafiya kwanaki 2 kafin ranar da aka sanya kuma ana ci gaba da kwana 2 bayan gwajin.
Amfani da barasa
Haɗin haɗarin metformin da abubuwan sha mai haɗari shine ke haifar da rikitarwa mai wahala.
Tasiri kan ikon sarrafa abubuwan inji
Siofor ba ya ba da gudummawa ga raguwa mai yawa a cikin glycemia, saboda haka, babu ƙuntatawa lokacin tuki motocin yayin jiyya tare da wannan kayan aiki. Koyaya, yakamata a yi taka tsantsan yayin tuki.
Yi amfani da lokacin daukar ciki da lactation
Kada kuyi amfani da magani na marasa lafiya a waɗannan halayen, saboda babu isasshen bayani game da amincin miyagun ƙwayoyi.
Ba da shawarar a ɗauki wannan kayan aiki ga marasa lafiya waɗanda ba su shekara 10 ba.
Nadin Siofor ya yiwa yara 500
Ba da shawarar a ɗauki wannan kayan aiki ga marasa lafiya waɗanda ba su shekara 10 ba.
Yi amfani da tsufa
An yarda da miyagun ƙwayoyi don amfani.
Aikace-aikacen aiki mara kyau
Babban lahani ga wannan ƙwayar cuta shine dalilin dakatar da amfani da Siofor don dawo da matakin glycemia a cikin ciwon sukari mellitus. Determinaddarawar ƙuduri shine raguwa a cikin maida hankali ga creatinine zuwa 60 ml a minti daya.
Amfani don aikin hanta mai rauni
A cikin mummunan cututtuka na wannan sashin, ba a ba da shawarar Siofor ba.
Yawan damuwa
Idan an dauki kashi na metformin 85 g, wasu sakamako masu illa ba sa ci gaba. Lokacin da adadin abu ya ƙaru sosai, haɗarin alamun lactic acidosis yana ƙaruwa. A wannan yanayin, ana buƙatar asibiti. Rage taro na lactic acid da metformin a cikin jini ta amfani da hemodialysis.
Yin hulɗa tare da wasu kwayoyi
Abubuwan haɗin gwiwa
Abun dacewa da aidin-dauke da bambancin wakilai da Siofor ba a yarda da su ba. A wannan yanayin, haɗarin haɓaka gazawar haɓaka yana ƙaruwa, a kan abin da alamun lactic acidosis ya bayyana.
Abun dacewa da aidin-dauke da bambancin wakilai da Siofor ba a yarda da su ba.
Ba da shawarar haɗuwa ba
Kada ku sha barasa yayin magani tare da miyagun ƙwayoyi a tambaya. A lokaci guda, haɗarin haɓaka lactic acidosis shima yana ƙaruwa. Sakamakon makamancin haka yana samar da haɗarin magunguna metformin da ethanol-kwayoyi.
Haɗuwa yana buƙatar taka tsantsan
Danazole yana taimakawa haɓaka ƙwayar cutar glycemia. Idan akwai buƙatar gaggawa don ɗaukar wannan magani, ana buƙatar daidaita sashi na metformin.
Matsayi na glucose shima yana haɓaka tare da haɗuwa da wakilai masu zuwa, abubuwa:
- maganin hana haihuwa;
- kwayoyin hodar iblis;
- Epinephrine;
- nicotinic acid;
- glucagon;
- abubuwan da aka samo asali na phenothiazine.
Hankalin Siofor yana ƙaruwa sosai tare da maganin Nifedipine. Morphine da sauran magungunan cationic suna ba da sakamako iri ɗaya.
Abubuwan da suka samo asali na sulfonylureas, insulin - wadannan kwayoyi suna tsokani karuwa a cikin aikin metformin.
Magungunan da ke cikin tambaya yana taimakawa rage tasirin magungunan anticoagulants na kaika (asfirin, da sauransu).
Analogs
Masu yiwu maye gurbin Siofor:
- Diaformin;
- Glyformin;
- Glucophage Tsayi;
- Formmetin;
- Metformin da sauransu
Yanayin hutu Siofora 500 daga kantin magunguna
Magunguna magani ne.
Zan iya saya ba tare da takardar sayan magani ba?
A'a, zaka iya siyan magungunan kawai kamar yadda likitanka suka umurce ka.
Farashi
Matsakaicin matsakaici shine 250 rubles.
Yanayin ajiya na Siofor 500
Matsakaicin zafin jiki na yanayi shine + 25 ° C.
Ranar karewa
Magungunan sun riƙe kaddarorin na tsawon shekaru 3 daga ranar da aka sake su.
Mai masana'anta
Barcelona - Chemie AG (Jamus).
Nunawa game da Siofor 500
Likitoci
Vorontsova M.A., 45 years old, endocrinologist, Kaluga
Ina wajabta magunguna tare da tabbatar da juriya na insulin. Daga cikin majinyata akwai kuma yara kanana. An yarda da miyagun ƙwayoyi, bayyanar maras kyau yana faruwa akai-akai kuma akasari daga hanji. Bugu da kari, farashin yayi ƙasa, idan aka kwatanta da analogues.
Lisker A.V., 40 years old, therapist, Moscow
Magungunan yana aiki da sauri, yana da matuƙar tasiri. A saboda wannan dalili, ana iya amfani dashi don magance hyperglycemia kuma tare da burin rasa nauyi kawai bayan tuntuɓar likita. Siofor ya bambanta da yawa analogues a cikin hakan yana iya ba da gudummawa ga daidaituwar yanayin tare da kwayar polycystic. A wannan yanayin, mata suna da alamu daban-daban: gashi a jiki da fuska, nauyi yana ƙaruwa. Magungunan yana da tasiri matsakaici akan asalin hormonal, ana lura da cire gashi daga jiki, an rage nauyi.
Marasa lafiya
Veronika, shekara 33, Samara
Ta dauki maganin tare da maganin hawan jini. Siofor yayi aiki da sauri. Kuma ban lura da mummunan tasiri akan kaina ba.
Anna, 45 years, Sochi
Magungunan ba shi da tsada kuma yana da tasiri. An gano ciwon sukari na mellitus na dogon lokaci, a cikin maganata yana da wuya a zaɓi magungunan hypoglycemic, jiki ba ya tsinkaye su. Amma Siofor yana da matukar laushi.
Rage nauyi
Olga, mai shekara 35, garin Kerch
Ban yi asara ba yayin shan wannan maganin. Ina fatan cewa wasu kilo biyu zasu tafi. Weight har yanzu yana tsaye, amma aƙalla bai ƙara ƙaruwa ba, wanda shima yayi kyau.
Marina, shekara 39, Kirov
Ta kasance mai tsunduma cikin wasanni sosai (kamar yadda zai yiwu da ciwon sukari), akwai abinci mai daidaita. Sakamakon yana da rauni - nauyin bai kusan ba. Amma na yi biyayya da tsarin kulawa na dan wani lokaci, watakila wannan shine batun.