Insuman Bazal: umarnin don amfani, analogues, farashi

A yi gyaran sukari da ke cikin jikin mai haƙuri da ciwon sukari yakamata a yi akai-akai. Wannan yana buƙatar gudanarwa na yau da kullun, kuma mafi yawan lokuta injections, na magungunan hypoglycemic. Don saukakawa mafi girma, ana ba wa marasa lafiya damar yin amfani da kwayoyi a cikin alkalannin sirinji na musamman.

Don kyakkyawar fahimta, ya zama dole a san waɗanne magunguna za a iya amfani da su ta wannan hanyar. Ofaya daga cikin magunguna masu rage yawan sukari shine Insuman Bazal GT. Wannan magani yana nunawa ta hanyar asalin kwayar halitta - insulin na mutum.

Insuman Bazal yana da matsakaiciyar lokacin aikin wanda yakan faru bayan sa'a daya bayan an sha maganin. Babban sinadari mai aiki iri guda ga insulin na mutum shine tsaka tsaki na protamine na Harantorn (istinan insulin na isofan).

Masana kimiyya daga Kanada sun ci gaba da wannan maganin a cikin garuruwan. Tsawon lokacin aikin insulin da aka gabatar ya samu ta hanyar ƙara wa kansa takamaiman furotin - protamine. Godiya gareshi, tare da gabatar da wani magani, maganin toshewar jijiyoyin jini da kuma microvessels na jini, wanda ke rage yawan shan magungunan a cikin jini.

Abun ciki da nau'i na saki

Akwai insulin basal a cikin sigogin uku:

1. Cakuda a cikin vials biyar, kowane milliliters biyar;
2. Kwalba ɗaya a kowace millilili goma;
3. Kayan katako guda uku na milliliters, don alkalami na syringe. Kowane katun yana dauke da capsule tare da 1 ml na abu mai aiki.

Maƙeran katako suna da mashahuri sosai, saboda canjin su ba mai wahala bane, kuma amfani da alƙalami mai sassauƙa hanya ce mai dacewa kuma kusan mara wahala.

A cikin kowane kwalba ko kabad, a cikin 1 milliliter na abu shine kusan 100 IU na insulin.

Wannan magani mai rage sukari ya qunshi:

• Insulin mutum - shine babban sinadari mai aiki, ya wajaba a sanya ido sosai akan sashin da ake sarrafawa, domin kauce wa wucewar yawan insulin ko rashin isasshen aikin insulin, wanda hakan zai haifar da sakamako;
• M-cresol - a cikin wannan shirye-shiryen yana kunshe ne da ƙima kaɗan, yana wasa da matattara don ƙarin abubuwa, kuma a matsayin maganin antiseptik mai tasiri;
• Phenol - wannan acid yana aiki a matsayin wakili na antibacterial, ƙaramin adadin yana nan a cikin wannan magani. Tare da m-cresol, yana ba ku damar kula da yanayin ƙarancin ƙwayoyi, wanda zai kare mai haƙuri daga kamuwa da cuta;
• Sulfate na protamine - yana aiki ne a matsayin katangar insulin, wanda ke ba ka damar tsawanta tasirin ta kan jiki. Hakanan, wannan kayan zai iya toshe lumen tasoshin, wanda ke lalata shaye-shayen magungunan allura;
• Sodium dihydrogen phosphate - yana aiki azaman abu mai ƙura, yana ƙara kaddarorin kayan ruwa a cikin abubuwan da aka gabatar. Wajibi ne don tsawaita yawan insulin a cikin jini;
• Hydrochloric acid - yana sarrafa acidity na wannan magani.

Magunguna da magunguna

Wannan magani magani ne na insulin ɗan adam, kawai tare da ƙari da abubuwa waɗanda ke shafar sha da lokacin aiki.

Abun da ke rage yawan sukari na Insuman Bazal ya samu godiya ga:

1. Don haɓaka fitar da sukari daga jiki - yayin da akwai rauni mai rauni yana hana sha da fitsari a cikin ƙwayar mahaifa, tare da haɓaka fitar da sukari da ƙodan;
2. Samun yawan sukari ta hanyar kyallen jiki yana ƙaruwa - saboda wane ne, yawancin glucose yana shiga kyallen da ƙwayoyin jikin mutum, saboda wanda yawan haɗuwarsa a cikin jini yana raguwa;
3. Hanzarta liponeogenesis - wannan dukiya yana haifar da tsarin yawan kitse na jiki, kamar yadda ake canza carbohydrates a cikin jini a cikin gabobin ciki. Kuma sakamakon metabolite an sanya shi cikin ƙwayar subcutaneous, omentum, tsokoki da sauran kyallen takarda kamar mai;
4. Starfafawa na glyconeogenesis - a wannan yanayin, an samar da keɓaɓɓen wuri don glucose, wanda shine hadaddun polysaccharide. Tare da rashin glucose a cikin jini, wannan polysaccharide zai watsar da ƙara matakin a cikin jini;
5. Rage ƙira a cikin hanta da hanta - a cikin hanta akwai ƙwaƙwalwar metabolism, fats har ma da sunadarai, wanda a ƙarƙashin ƙayyadaddun enzymes na iya samar da glucose;
6. Samuwar masu karɓar insulin - wannan hadaddun yana kan mafitsara daga sel na jikin mutum, kuma yana ƙaruwa da haɓakar glucose a cikin jiki, wanda ke rage yawan haɗuwa da jini kuma yana haɓaka haɓakar sel. Ana amfani da wannan sakamako cikin nasara ga masu motsa jiki waɗanda ke son yin kyakkyawan sakamako ta amfani da insulin.

Tare da bin umarnin don amfani, Insuman Bazal, dole ne a gudanar dashi ƙarƙashin abu. Wannan ya zama dole don kauce wa karuwar haɓakar insulin a cikin jini. Sabili da haka, koyaushe ya kamata ku kula da lokacin gudanarwa da ƙididdige sa'ar allura ta gaba, saboda ana samun tasirin cutar a cikin sa'o'i 1-2 bayan gudanarwa, kuma ana lura da tasirin sakamako na tsawon sa'o'i 20 zuwa 20.

Alamu

Ana amfani da wannan magani a cikin ci gaban insulin-dogara da ciwon sukari mellitus na nau'in farko. Tabbas, tare da wannan bambancin cutar, an lura da raguwa a cikin kwayar insulin ta sel langerhans a cikin ƙwayar ƙwayar cuta, wanda ke buƙatar yin amfani da maganin maye.

Ana amfani da wannan magani azaman maganin insulin na tsawon lokaci, ana iya haɗa shi tare da insulin na cikin sauri insulin Rapid.

Sashi

Yi amfani da Insuman Bazal GT a cikin allon alkalami ko tare da sirinji insulin, yana da mahimmanci don haɗa kai tare da likitanka. A wannan yanayin, ya kamata a fara liyafar maraba a cikin asibiti a ƙarƙashin kulawar ƙwararrun masani. Zai taimaka wajen daidaita yawan aikin da ake buƙata na insulin, sarrafa gabatarwar servings na yau da kullun na miyagun ƙwayoyi, da kuma lura da amsawar jikin jikin wannan magani.

Babu takamaiman takamaiman magunguna don amfanin irin waɗannan ƙwayoyi, tunda an zaɓi kashi ɗaya don kowane mai haƙuri. Ana lissafta kashi na yau da kullun gwargwadon nauyin jikin mutum kuma shine 0.4-1.0 U / kg.

Lokacin yin lissafin sashi, ya zama dole muyi la’akari da yadda mai haƙuri yake bi da maganin da aka tsara, wanda ke jagorantar salon rayuwa, ayyukanta a rana. Dole ne a gudanar da wannan magani a ƙarƙashin subcutaneously. Da ake bukata wani canji ne na wurin allurar. Wannan ya zama dole saboda takamaiman aikin da miyagun ƙwayoyi ke ciki, da kuma hana haɓaka halakar nama da jijiyoyin jini tare da gudanar da maganin.

Irin waɗannan ayyuka dole ne a haɗa su tare da likitan halartar. Tun da sassa daban-daban na jiki suna da matsayi daban-daban na haɓakar hanyar haɓaka jini da jijiyoyin jini, saboda wannan, ɓangaren insulin shiga jini zai iya canzawa.

Likita yakamata yayi la'akari da yadda matakan glucose suke canzawa yayin da ake gudanar da insuman a wurare daban-daban na allurar.

Lokacin amfani da Insuman Bazal, yakamata a yi la'akari da abubuwan da ke zuwa:

• Wurin gabatarwa;
• Canje-canje a cikin nauyin jiki - tare da haɓaka, sashi yana ƙaruwa daidai da haka, a wannan yanayin juriya nama zai iya faruwa, haɓaka mai yawa a cikin haɗuwa da glucose da haɓaka yanayin tashar;
• Canji a cikin tsarin abinci da salon rayuwa - rage cin abinci don ciwon sukari yana nufin kiyaye matakan sukari na jini a cikin kullun, idan ana canza yanayin abinci ko canza menu na yau da kullun, dole mahimmancin magungunan dole ne a sake tara su. Dole ne a aiwatar da irin waɗannan ayyuka bayan canza salon rayuwarsu, a wasu yanayi, marasa lafiya suna buƙatar ƙaramin insulin (hoto mai aiki), kuma a wasu, babban kashi (rashin lafiya, aiki na raguwa);
• Sauyawa zuwa insulin ɗan adam daga dabba - irin wannan matakin yana faruwa ne kawai a ƙarƙashin kulawar likitan halartar, kawai dole ne ya daidaita sashi. A cikin masu ciwon sukari, akwai karuwa mai mahimmanci ga insulin mutum, saboda haka mafi yawan lokuta ana rage yawan maganin.

Tare da haɓakar cututtuka tare da lalacewar hanta ko haifar da shi, ya kamata a aiwatar da iko na glucose, kuma yawan sukari na rage magungunan da ake sarrafawa ya kamata a rage. Tunda an rage yawan motsa jiki na insulin, kazalika da tsarin glucose a cikin hanta.

Kariya da aminci

Kafin yin amfani da miyagun ƙwayoyi kai tsaye, kuna buƙatar tabbatar da ingancin ta. Don yin wannan, kana buƙatar ɗaukar kwalba, kuma ka tabbata cewa akwai filastik na filastik wanda ya ce ba a buɗe ba. Sannan tantance yanayin maganin cutar kansa.

Ya kamata fari, opaque, daidaito da daidaito. Idan hazo, kasancewar flakes, ana lura da dakatarwar da kanta, wannan yana nuna yanayin rashin magani.

Kafin bugawa, dakatarwar dole ne a haɗe shi da kyau. A cikin sirinji, zana iska bisa ga adadin da ake so kuma shigar da shi cikin murfin ba tare da taɓa dakatarwa ba. Bayan haka, ba tare da fitar da allurai ba, juya kwalban a tattara kayan da ake so na Insuman.

Game da batun yin amfani da almarar sirinji da katako, shi ma ya wajaba a tantance yanayin dakatarwar da kanta da kuma aikin alkairin sirinji. Kafin gudanarwa, kuna buƙatar juyawa ko girgiza na'urar a hankali sau da yawa don dakatarwar da tayi.

Idan alkalami ya karye kuma babu damar sayan sabo a daidai wannan lokacin, zaku iya amfani da sirinji. Insuman Bazal ya ƙunshi 100 IU / ml, babban sinadaran aiki, don haka kuna buƙatar amfani da sirinji waɗanda aka tsara musamman don wannan maganin.

Side effects

A kan tushen amfani da Insuman, koyaushe ci gaban:

1. Hypoglycemia - a cikin yanayin yawan insulin wanda ya wuce na yau da kullun, ko kuma idan jikin baya buƙatar ɗayan;
2. Hyperglycemia - yana tasowa sau da yawa, yana nuna isasshen kashi na insulin ko raguwa a cikin jijiyar jikin mutum ga ƙwayoyi.

Irin waɗannan halaye suna haɗuwa da tsananin tsananin farin ciki, yiwuwar asarar hankali, fargaba, jin ƙarfi na yunwar. Hakanan akwai ciwon kai mai wahala, damuwa, damuwa, da rikicewar motsi.

Tare da ci gaba da raguwa a cikin matakan sukari, marasa lafiya suna haɓaka tachycardia, raguwar hauhawar jini, da fatar fata.

Yawancin lokaci yana raguwa da haɓaka a cikin glucose na iya barin tasiri wanda ba a ke so ga lafiyar ɗan adam. A irin waɗannan halayen, yanayin ɓarkewar ƙananan jijiyoyin haɓaka tashoshi iri daban-daban. Mafi yawan lokuta, akwai rauni na gani, duhu cikin idanu. Wannan halin da jijiyoyin jini ke haifar da ci gaban makanta.

Tare da gabatarwar insulin akai-akai a wuri guda, atrophy na ƙwayar subcutaneous yana tasowa a can, tabo ya faru. Hakanan, irin waɗannan ayyukan zasu iya haifar da haɓakar ƙurji ko ƙashin ƙarancin nama.

Hankalin rashin hankali zai iya haɓakawa a cikin sassan Insuman, wanda ke tattare da mummunan itching, fitsari a kan fata, tare da raɗaɗi mai raɗaɗi ko baƙar fata, yana nuna alamar ƙwayar jijiyoyin jiki (sabon abu na arthus). Wataƙila bayyanar matsalolin numfashi, yana nuna haɓakar bronchospasm, angioedema, jan launi duka fata.

Yawan damuwa

Tare da gabatarwar babban adadin insulin, wani mummunan yanayin rashin ƙarfi na jiki yana tasowa. Lokacin da alamun farko suka bayyana, ya zama dole a dauki matakan da nufin dakatar da wannan yanayin. Da farko, kuna buƙatar yin gwajin bayyani don matakin sukari na jini. Idan alamu ba su da ƙasa, kana buƙatar ɗaukar ɗan sukari kaɗan a ciki.

Idan aka rasa asara, ana ba da ragamar yaduwar glucose ga wanda aka azabtar, a cikin ciki, sannan a haɗa daskararre tare da maganin gurza na glucose. Bayan haka ana sanya mara lafiya a cikin kallo kuma ana auna matakan sukarin jini akai-akai.

Yin hulɗa tare da wasu kwayoyi

Amfani guda daya na bambance-bambancen magunguna masu rage yawan sukari zai haifar da ci gaban cututtukan cututtukan jini, ya wajaba don daidaita ciwan magunguna tare da likitanka.

Hakanan haramun ne don ɗaukar Insuman tare da kwayoyi waɗanda zasu iya rage tasirin maganin antidiabetic, sun haɗa da: emtrogens, sympathomimetics, hormones thyroid, diuretics, somatotropin da analogues, magungunan antipsychotic.

Idan mai haƙuri yana buƙatar shan irin waɗannan ƙwayoyi, irin waɗannan lokacin dole ne a yarda da likitan halartar.

Analogs da kimanin farashin

Farashin insuman tushe a kan ƙasar Rasha ya tashi daga 765,00 rubles zuwa 1,585 rubles.

Idan ya cancanta, zamu iya daidaitawa tare da amfani da makomar sauran maganganun insuman Bazal. Kusan daidai suke a cikin abubuwan da aka tsara da kuma tsawon lokacin aiki. Suna kuma ƙunshe da dan asalin insulin na ɗan adam, tare da ƙari da sauran magabata.

Analogs na Insuman Bazal sune:

1. Protafan TM, samarwa - Denmark. Ana iya siyan wannan hypoglycemic akan farashin 850 rubles zuwa 985 rubles.
2. Rinsulin NPH, samarwa - Rasha. Ana samun wannan kayan aiki a cikin kwalabe da katako, zaku iya siyarwa a farashin 400 rubles zuwa 990 rubles.
3. Humulin NPH, Production - Amurka. A cikin kantin magunguna za'a iya samun su a farashin 150-400 rubles.