Type 2 diabetes mellitus (T2DM) cuta ce ta tsari, a yayin haɓaka wanda ƙwayoyin jikin mutum ke rasa hankalinsu ga insulin kuma su daina shan glucose, a sakamakon hakan ne ya fara zama cikin jini. Don hana tara sukari mai yawa a cikin jini, likitoci sun ba da shawarar masu ciwon sukari a koyaushe su kan rage karancin abinci da motsa jiki. Koyaya, waɗannan matakan ba koyaushe suna ba da sakamako mai kyau ba, kuma cutar ta fara ci gaba, wanda ke tilasta mutum ya matsa zuwa mafi munanan al'amuran - don yin karatun likita. Amma akwai wani sabon abu a cikin lura da ciwon sukari na 2, wanda za'a tattauna yanzu.
Bayan 'yan kalmomi game da cutar
Ba kamar nau'in ciwon sukari na 1 ba, T2DM yana da lafiya sosai idan an fara shi akan lokaci. Tare da wannan cutar, an kiyaye aikin ƙwayar ƙwayar cuta, wato, babu rashi insulin a cikin jiki, kamar yadda a farkon yanayin. Saboda haka, ba a da bukatar warkewar magani anan ba.
Koyaya, ba da gaskiya cewa tare da haɓaka T2DM matakan sukari na jini ya wuce na yau da kullun, ƙwaƙwalwar "tayi imani" cewa ba ta aiki cikakke kuma yana haɓaka samar da insulin. A sakamakon wannan, ƙwayar cuta tana fuskantar mummunan damuwa a koyaushe, wanda ke haifar da lalacewar hankali akan ƙwayoyinta da canzawar T2DM zuwa T1DM.
Sabili da haka, likitoci suna ba da shawarar cewa marasa lafiyarsu a kai a kai suna lura da matakin sukari a cikin jini kuma, idan ya haɓaka, nan da nan suna ɗaukar matakan da za su ba da damar rage shi ga iyakoki na al'ada. Tare da T2DM, ya isa kawai bin tsarin abinci da motsa jiki matsakaici. Idan wannan bai taimaka ba, zaku iya neman taimakon magunguna masu rage sukari.
Amma duk waɗannan hanyoyin maganin cututtukan ƙwayar cuta suna daɗaɗawa. Kuma yin la’akari da gaskiyar cewa yawan mutanen da ke fama da wannan cuta na karuwa a kowace shekara, likitoci suna kara yin amfani da sabon nau'in cutar sankarar mellitus da masana kimiyya da kamfanoni daban-daban na magunguna ke bayarwa. Shin suna baka damar kayar da wannan cutar, ko kuma aƙalla hana ta ci gaba? Za a tattauna wannan da abubuwa da yawa yanzu.
Gzitazones
Sabbin hanyoyin magance T2DM suna ba da shawarar amfani da kwayoyi na sababbin mutanen, waɗanda suka haɗa da abin da ake kira glitazones. An kasu kashi biyu - pioglitazones da rosiglitazones. Waɗannan abubuwa masu aiki suna ba da gudummawa ga haɓakar masu karɓar mahaɗan da ke cikin nuclei na adipose da ƙwayoyin tsoka. Lokacin da aka kunna waɗannan girke-girke, akwai canji a cikin fassarar kwayoyin halittar da ke da alhakin kayyade glucose da ƙwayoyin tsoka, sakamakon abin da ƙwayoyin jikin mutum ke fara hulɗa tare da insulin, kwashe glucose da hana shi daidaitawa cikin jini.
Hanyar aikin glitazones
Wadannan kwayoyi suna cikin rukunin pioglitazones:
- Aktos
- Diab-na yau da kullun
- Piroglar.
Ana yin wannan shan magunguna ne sau 1 kawai a rana, ba tare da la’akari da lokacin cin abinci ba. A farkon farawar magani, sashinsu shine 15-30 mg. A cikin abin da ya faru da cewa pioglitazone ba ya ba da sakamako mai kyau a cikin irin waɗannan adadi, an ƙara adadin sa zuwa 45 MG. Idan an sha maganin a hade tare da wasu magunguna don maganin T2DM, to matsakaicin matakin da ya kamata ya wuce 30 MG kowace rana.
Amma game da rosiglitazones, waɗannan magunguna masu zuwa na rukunin su ne:
- Avandiya
- Roglit.
Ana ɗaukar waɗannan magungunan kwanan nan ta baki sau da yawa a rana, kuma ba tare da la'akari da lokacin cin abinci ba. A matakan farko na maganin, maganin yau da kullun na rosinlitazone shine 4 MG (2 MG a lokaci guda). Idan ba'a lura da tasirin ba, ana iya karuwa zuwa 8 MG. Lokacin gudanar da aikin haɗin gwiwa, ana ɗaukar waɗannan magunguna a cikin ƙananan allurai - ba fiye da 4 MG kowace rana.
Magungunan "Actos" yana nufin sabon aji na kwayoyi
Kwanan nan, ana ƙara yin amfani da waɗannan magunguna a magani don magance cututtukan type 2. Dukansu rosiglitizans da pioglitazones suna da fa'idodi masu yawa. Bikin liyafar nasu ya tanadi:
- raguwa a cikin juriya na insulin;
- toshewar lipolysis, yana haifar da raguwa a cikin yawan kitse mai kitse a cikin jini, wanda hakan ke cutar da sake fasalin sinadarin adipose;
- raguwa a cikin triglycerides;
- levelsara yawan matakan jini na HDL (yawan ƙwayoyin lipoproteins mai yawa).
Godiya ga duk waɗannan ayyuka, lokacin ɗaukar waɗannan magunguna, an sami sakamako mai ƙarko don ciwon sukari mellitus - matakin sukari na jini kusan kusan koyaushe yana cikin iyakoki na al'ada kuma yanayin yanayin haƙuri yana inganta.
Koyaya, waɗannan kwayoyi ma suna da rashin nasara:
- glitazones ba su da ƙarfi a cikin '' yan uwansu ", waɗanda ke da alaƙa da ƙungiyoyin sulfonylurea da metformins;
- rosiglitazones suna contraindicated idan akwai matsaloli daga tsarin zuciya, saboda suna iya haifar da bugun zuciya ko bugun jini (kuma tsarin zuciya da jijiyoyin jini ya shafi farko);
- glitazones yana haɓaka ci da kuma ƙara yawan nauyin jiki, wanda ba a buƙaci shi a cikin ci gaban nau'in ciwon sukari na 2, saboda wannan na iya haifar da sauran matsalolin kiwon lafiya da canzawar T2DM zuwa T1DM.
Saboda kasancewar yawan sakamako masu illa da contraindications a cikin wadannan kwayoyi, ba shi yiwuwa a sha su ba tare da sanin likita ba
Manuniya da contraindications
Ana iya amfani da Pioglitazones da rosiglitazones duka biyu azaman magunguna masu tsayawa kawai don maganin T2DM, kuma a hade tare da sulfonylurea da metformin (ana amfani da maganin haɗin gwiwa don rashin lafiya mai tsanani). A matsayinka na mai mulkin, ana rubutasu ne kawai idan maganin rage cin abinci da matsakaiciyar motsa jiki ba su bayar da sakamako mai kyau.
Babban contraindications ga yin amfani da pioglitazones da rosiglitazones sune abubuwa masu zuwa na ilimin halayyar jiki da yanayin:
- ciki da lactation;
- shekaru har zuwa shekaru 18;
- nau'in ciwon sukari na 1 da sauran yanayin da ake buƙatar insulin farji;
- wuce matakin ALT ta fiye da sau 2,5;
- hepatic cututtuka a cikin m lokaci.
Dole ne likita ya wajabta maganin "Avandia"
Baya ga gaskiyar cewa waɗannan sababbin magunguna suna da contraindications, suna kuma da sakamako masu illa. Mafi yawan lokuta, lokacin da aka dauke su a cikin marasa lafiya, ana lura da masu zuwa:
Sabbin Magungunan Ciwon Cutar 2- Edema, bayyanar wanda shine lalacewa ta hanyar ƙarfin abubuwan aiki na waɗannan kwayoyi don riƙe ruwa a cikin jiki. Kuma wannan na iya yin illa ga aikin ƙwaƙwalwar zuciya, da haɓaka haɗarin haɓaka bugun zuciya, lalatawar zuciya da sauran yanayin barazanar rayuwa na haƙuri.
- Raguwar matakin hawan jini a cikin jini (anaemia), wanda ya cika da faruwar matsaloli a ɓangaren kwakwalwa, yayin da ya fara fuskantar matsananciyar yunwar oxygen. A mafi yawancin halayen, saboda matsalar cutar sankara, akwai take hakkin wurare dabam dabam, rage ƙwaƙwalwar ƙwayar cuta, rashin dacewar CNS, da sauransu. Duk waɗannan yanayin ba su da tasiri ga yanayin mai haƙuri.
- Keta ayyukan enzymes hanta (ALT da AST), wanda ke haifar da ci gaban faduwar hanta da sauran yanayin cututtukan. Saboda haka, lokacin shan pioglitazones da resiglitazones, dole ne a kai a kai gwajin jini na biochemical. Kuma a cikin wancan
idan matakin waɗannan enzymes ya wuce na yau da kullun ta hanyar fiye da sau 2,5, ana buƙatar soke wannan magungunan nan da nan.
Baranzaman
Wani sabon rukuni na kwayoyi da aka fara amfani da su kwanan nan don magance cututtukan type 2. Daga cikin waɗannan, mafi mashahuri sune Exenatide da Sitagliptin. A matsayinka na mai mulkin, ana amfani da waɗannan magunguna a hade tare da Metformin.
Incretinomimetics suna taimakawa ga:
- ƙarancin ɓoye insulin;
- tsari na samar da ruwan 'ya'yan itace na ciki;
- rage gudu da narkewar abinci da kuma narke abinci, wanda ke tabbatar da hana yunwa da asarar nauyi.
Lokacin shan ingretinomimetics, tashin zuciya da zawo na iya faruwa. Koyaya, a cewar likitocin, waɗannan cututtukan suna faruwa ne kawai a farkon farfaɗo. Da zaran jiki ya saba da miyagun ƙwayoyi, sai suka ɓace (yana ɗaukar kimanin kwanaki 3-7).
Incretinomimetics suna da kwayoyi masu iko sosai, kuma idan akayi amfani dasu ba da kyau ba, zasu iya haifar da mummunar matsalar kiwon lafiya.
Wadannan kwayoyi suna ba da haɓaka matakin insulin a cikin jini kuma suna toshe tsarin haɗin glucagon, wanda ke daidaita matakin sukari a cikin jini kuma yana inganta yanayin mai haƙuri gaba ɗaya. Ingretinomimetics suna da sakamako mai ɗorewa, sabili da haka, don samun sakamako mai ɗorewa, ya isa ya ɗauka su sau 1 kawai a rana.
Kara sel
Kulawa da nau'in ciwon sukari na 2 na ƙwayar cuta tare da ƙwayoyin kara yana da tsada amma hanya mafi inganci. Ana amfani dashi a cikin matsanancin yanayi, lokacin da magani ba ya ba da sakamako.
Yin amfani da kwayoyin halitta a cikin lura da ciwon sukari na iya cimma sakamako mai zuwa:
- cikakken maido da ayyukan cututtukan farji da karuwar insulin;
- normalization na rayuwa tafiyar matakai;
- kawar da cututtukan endocrine.
Godiya ga amfani da ƙwayoyin kara, yana iya yiwuwa don kawar da ciwon sukari gabaɗaya, wanda a baya abin da ba daidai bane a cimma. Koyaya, irin wannan magani yana da matsala. Baya ga gaskiyar cewa wannan hanyar tana da tsada sosai, kuma ba a fahimta sosai, kuma yin amfani da ƙwayoyin kara a cikin mara haƙuri na iya haifar da halayen da ba a zata na jiki.
Magnetotherapy
Babban dalilan ci gaban nau'in ciwon sukari na 2 shine yawan damuwa da damuwa, wanda ke tsokane samar da kwayoyin halittar a jikin mutum kamar thyroxine da adrenaline. Don aiwatar da waɗannan kwayoyin halittar, jikin yana buƙatar isashshen sunadarin oxygen, wanda zaku iya samun dama daidai ta hanyar tsananin motsa jiki.
Magnetorepy yana samar da sabunta tsarin juyayi na tsakiya da haɓaka haƙuri
Amma tun da yawancin mutane ba su da lokacin yin wasanni, waɗannan kwayoyin halittar suna tarawa a cikin jiki, suna tsoratar da matakai iri daban-daban na ciki. Kuma nau'in ciwon sukari na 2 ya fara haɓaka. A wannan yanayin, yin amfani da magnetotherapy yana da tasiri sosai, wanda ke kunna aikin dukkanin gabobin ciki kuma yana inganta aiki na thyroxine da adrenoline, ta hakan yana hana ci gaba da cutar da kuma daidaita matakan sukari na jini.
Koyaya, yin amfani da magnetotherapy koyaushe ba zai yiwu ba. Tana da maganin ta, wadanda suka hada da:
- tarin fuka
- ciki
- hypotension;
- zazzabi mai zafi;
- cututtukan oncological
Duk da cewa hanyoyin da yawa na kamuwa da ciwon sukari na 2 sun bayyana a cikin magani, ya kamata a fahimci cewa an fahimci su duka. Amfani da su na iya haifar da mummunan sakamako. Sabili da haka, idan ka yanke shawarar gwada sababbin hanyoyin magance wannan cutar, yin tunani a hankali kuma tattauna dukkan rashin lafiyar tare da likitan ku.
